{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:21:55Z","timestamp":1791127315631,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology International"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.parint.2005.11.007","type":"journal-article","created":{"date-parts":[[2005,12,20]],"date-time":"2005-12-20T14:05:58Z","timestamp":1135087558000},"page":"S51-S55","source":"Crossref","is-referenced-by-count":105,"special_numbering":"S","title":["Survival strategy of Echinococcus multilocularis in the human host"],"prefix":"10.1016","volume":"55","author":[{"given":"Dominique Ang\u00e8le","family":"Vuitton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao Ling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yurong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Godot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Beurton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Mantion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange","family":"Bresson-Hadni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.parint.2005.11.007_bib1","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1017\/S0031182003004153","article-title":"Epidemiology of alveolar echinococcosis with particular reference to China and Europe","volume":"127","author":"Vuitton","year":"2003","journal-title":"Parasitology"},{"key":"10.1016\/j.parint.2005.11.007_bib2","doi-asserted-by":"crossref","first-page":"576","DOI":"10.4269\/ajtmh.1987.36.576","article-title":"Spontaneous death of Echinococcus multilocularis: case diagnosed serologically (by Em2-Elisa) and clinical significance","volume":"36","author":"Rausch","year":"1987","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.parint.2005.11.007_bib3","doi-asserted-by":"crossref","first-page":"837","DOI":"10.4269\/ajtmh.1994.51.837","article-title":"Seroepidemiologic screening of Echinococcus multilocularis infection in a European area endemic for alveolar echinococcosis","volume":"51","author":"Bresson-Hadni","year":"1994","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.parint.2005.11.007_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4269\/ajtmh.2002.66.23","article-title":"Combined ultrasonographic and serological screening of hepatic alveolar echinococcosis in central China","volume":"66","author":"Bartholomot","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.parint.2005.11.007_bib5","doi-asserted-by":"crossref","first-page":"408","DOI":"10.3201\/eid0703.017307","article-title":"Is high prevalence of Echinococcus multilocularis in wild and domestic animals associated with disease incidence in humans?","volume":"7","author":"Gottstein","year":"2001","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.parint.2005.11.007_bib6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0020-7519(76)90008-4","article-title":"The effect of immunosuppression on secondary Echinococcus multilocularis infections in mice","volume":"6","author":"Baron","year":"1976","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.parint.2005.11.007_bib7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0020-7519(92)90075-V","article-title":"Effects of cyclosporin A on the course of murine alveolar echinococcosis and on specific cellular and humoral immune responses against Echinococcus multilocularis","volume":"22","author":"Liance","year":"1992","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.parint.2005.11.007_bib8","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/hep.510300426","article-title":"Primary disease recurrence after liver transplantation for alveolar echinococcosis: long term evaluation in 15 patients","volume":"30","author":"Bresson-Hadni","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.parint.2005.11.007_bib9","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0022-3476(97)70364-0","article-title":"Alveolar echinococcosis of the liver in a six-year-old girl with acquired immunodeficiency syndrome","volume":"130","author":"Sailer","year":"1997","journal-title":"J Pediatr"},{"key":"10.1016\/j.parint.2005.11.007_bib10","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3201\/eid0903.020341","article-title":"European echinococcosis registry: human alveolar echinococcosis, Europe, 1982\u20132000","volume":"9","author":"Kern","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.parint.2005.11.007_bib11","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.trstmh.2005.04.020","article-title":"Brain metastasis of alveolar echinococcosis in a hyperendemic focus of Echinococcus multilocularis infection","volume":"99","author":"Yang","year":"2005","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.parint.2005.11.007_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0001-706X(02)00230-9","article-title":"The ambiguous role of immunity in echinococcosis: protection of the host or of the parasite?","volume":"85","author":"Vuitton","year":"2002","journal-title":"Acta Trop"},{"key":"10.1016\/j.parint.2005.11.007_bib13","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1128\/IAI.70.3.1168-1174.2002","article-title":"Increased activation and oligoclonality of peripheral CD8(+) T cells in the chronic human helminth infection alveolar echinococcosis","volume":"70","author":"Manfras","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.parint.2005.11.007_bib14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/intimm\/dxh005","article-title":"Impeded Th1 CD4 memory T cell generation in chronic-persisting liver infection with Echinococcus multilocularis","volume":"16","author":"Manfras","year":"2004","journal-title":"Int Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s12016-004-0004-2","article-title":"Echinococcosis and allergy","volume":"26","author":"Vuitton","year":"2004","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib16","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1046\/j.1365-2249.2000.01308.x","article-title":"Resistance\/susceptibility to Echinococcus multilocularis infection and cytokine profile in humans: I. Comparisons of patients with progressive and abortive lesions","volume":"121","author":"Godot","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1046\/j.1365-3024.2001.00374.x","article-title":"Dendritic cells pulsed with unfractionated helminthic proteins to generate antiparasitic cytotoxic T lymphocyte","volume":"23","author":"Jenne","year":"2001","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.1365-2567.1999.00723.x","article-title":"Nitric oxide-mediated immunosuppression following murine Echinococcus multilocularis infection","volume":"97","author":"Dai","year":"1999","journal-title":"Immunology"},{"key":"10.1016\/j.parint.2005.11.007_bib19","unstructured":"Zhang SL, 2004. Genes and molecules relating to human Major Histocompatibility Complex in inflammatory diseases. Study of TAP polymorphism and MICA molecules expression. PhD thesis (Universit\u00e9 de Franche-Comt\u00e9, France, and Sun Yat Sen University, PR China)."},{"key":"10.1016\/j.parint.2005.11.007_bib20","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0168-8278(01)00135-0","article-title":"Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis","volume":"35","author":"Grenard","year":"2001","journal-title":"J Hepatol"},{"key":"10.1016\/j.parint.2005.11.007_bib21","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1046\/j.1365-2249.2000.01309.x","article-title":"Resistance\/susceptibility to Echinococcus multilocularis infection and cytokine profile in humans: II. Influence of the HLA B8, DR3, DQ2 haplotype","volume":"121","author":"Godot","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib22","unstructured":"Yang YR, 2005. Epidemiological, clinical and molecular studies on echinococcosis in Ningxia Hui Autonomous Region, The People's Republic of China. PhD Thesis (University of Queensland, Australia)."},{"key":"10.1016\/j.parint.2005.11.007_bib23","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/256318a0","article-title":"BCG suppresses growth and metastasis of hydatid infections","volume":"256","author":"Rau","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.parint.2005.11.007_bib24","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1086\/516316","article-title":"Clinical efficacy of and immunologic alterations caused by interferon gamma therapy for alveolar echinococcosis","volume":"26","author":"Jenne","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.parint.2005.11.007_bib25","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1046\/j.1365-3024.1998.00131.x","article-title":"In vivo treatment with recombinant IL-12 protects C57BL\/6J mice against secondary alveolar echinococcosis","volume":"20","author":"Emery","year":"1998","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.parint.2005.11.007_bib26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1086\/520157","article-title":"Clinical efficacy of and switch from T helper 2 to T helper 1 cytokine profile after interferon alpha2a monotherapy for human echinococcosis","volume":"29","author":"Harraga","year":"1999","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.parint.2005.11.007_bib27","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/S0016-5085(03)00273-7","article-title":"In vivo treatment with IFNalpha-2a protects C57BL\/6J mice against a helminth infection of the liver and modulates immune responses","volume":"124","author":"Godot","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.parint.2005.11.007_bib28","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0264-410X(02)00517-0","article-title":"The Echinococcus multilocularis 14-3-3 protein protects mice against primary but not secondary alveolar echinococcosis","volume":"21","author":"Siles-Lucas","year":"2003","journal-title":"Vaccine"}],"container-title":["Parasitology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576905001108?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576905001108?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T13:30:49Z","timestamp":1554989449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383576905001108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":28,"alternative-id":["S1383576905001108"],"URL":"https:\/\/doi.org\/10.1016\/j.parint.2005.11.007","relation":{},"ISSN":["1383-5769"],"issn-type":[{"value":"1383-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}