{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:37:26Z","timestamp":1761302246482,"version":"build-2065373602"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15H05633","15K14850","16H06429","16H06431","16K21723"],"award-info":[{"award-number":["15H05633","15K14850","16H06429","16H06431","16K21723"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parasitology International"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.parint.2020.102247","type":"journal-article","created":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T10:04:55Z","timestamp":1606039495000},"page":"102247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Characterization of microRNAs expressed in the cystic legion of the liver of Mus musculus perorally infected with Echinococcus multilocularis Nemuro strain"],"prefix":"10.1016","volume":"81","author":[{"given":"Yuhei","family":"Imasato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Irie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Kouguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinpei","family":"Yagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nonaka","family":"Nariaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Katakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.parint.2020.102247_bb0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.parint.2020.102247_bb0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007640","article-title":"Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL\/6 mice","volume":"14","author":"Boubaker","year":"2020","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.parint.2020.102247_bb0015","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.pt.2015.09.003","article-title":"MicroRNAs in parasitic helminthiases: Current status and future perspectives","volume":"32","author":"Cai","year":"2016","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.parint.2020.102247_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003965","article-title":"Circulating miRNAs: potential novel biomarkers for hepatopathology progression and diagnosis of schistosomiasis Japonica in two murine models","volume":"9","author":"Cai","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.parint.2020.102247_bb0025","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3892\/etm.2011.411","article-title":"RNA expression profile in primary gastric cancers and paired lymph node metastases indicates that miR-10a plays a role in metastasis from primary gastric cancer to lymph nodes","volume":"3","author":"Chen","year":"2012","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.parint.2020.102247_bb0030","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1017\/S0031182013000917","article-title":"Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum","volume":"140","author":"Cheng","year":"2013","journal-title":"Parasitol"},{"key":"10.1016\/j.parint.2020.102247_bb0035","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ijpara.2014.12.003","article-title":"High-throughput characterization of Echinococcus spp. metacestode miRNomes","volume":"45","author":"Cucher","year":"2015","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.parint.2020.102247_bb0040","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.ijpara.2010.11.010","article-title":"Identification of Echinococcus granulosus microRNAs and their expression in different life cycle stages and parasite genotypes","volume":"41","author":"Cucher","year":"2011","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.parint.2020.102247_bb0045","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","article-title":"Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern","volume":"17","author":"Eckert","year":"2014","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.parint.2020.102247_bb0050","first-page":"48","article-title":"World Health Organization. WHO\/OIE manual on echinococcosis in humans and animals: A public health problem of global","author":"Eckert","year":"2001","journal-title":"concern"},{"key":"10.1016\/j.parint.2020.102247_bb0055","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1080\/15476286.2019.1593094","article-title":"Small molecules with big roles in microRNA chemical biology and microRNA-targeted therapeutics","volume":"16","author":"Fan","year":"2019","journal-title":"RNA Biol."},{"key":"10.1016\/j.parint.2020.102247_bb0060","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1017\/S0031182017000300","article-title":"Expression profiling of circulating miRNAs in mouse serum in response to Echinococcus multilocularis infection","volume":"144","author":"Guo","year":"2017","journal-title":"Parasitol"},{"key":"10.1016\/j.parint.2020.102247_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002701","article-title":"Parasite-derived microRNAs in host serum as novel biomarkers of helminth infection","volume":"8","author":"Hoy","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.parint.2020.102247_bb0070","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/2041-9139-5-10","article-title":"The unique stem cell system of the immortal larva of the human parasite Echinococcus multilocularis","volume":"5","author":"Koziol","year":"2014","journal-title":"Evodevo"},{"key":"10.1016\/j.parint.2020.102247_bb0075","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/cdd.2009.58","article-title":"miR-10 in development and cancer","volume":"17","author":"Lund","year":"2009","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.parint.2020.102247_bb0080","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.parint.2010.06.003","article-title":"Primary alveolar echinococcosis: course of larval development and antibody responses in intermediate host rodents with different genetic backgrounds after oral infection with eggs of Echinococcus multilocularis","volume":"59","author":"Matsumoto","year":"2010","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.parint.2020.102247_bb0085","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3389\/fphar.2019.00488","article-title":"Enhanced inhibition of tumorigenesis using combinations of miRNA-targeted therapeutics","volume":"10","author":"Miroshnichenko","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.parint.2020.102247_bb0090","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.parint.2009.07.010","article-title":"Geographic pattern of genetic variation in the fox tapeworm Echinococcus multilocularis","volume":"58","author":"Nakao","year":"2009","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.parint.2020.102247_bb0095","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.ijpara.2011.06.007","article-title":"Identification of genetic loci affecting the establishment and development of Echinococcus multilocularis larvae in mice","volume":"41","author":"Nakao","year":"2011","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.parint.2020.102247_bb0100","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature12031","article-title":"The genomes of four tapeworm species reveal adaptations to parasitism","volume":"496","author":"Tsai","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.parint.2020.102247_bb0105","doi-asserted-by":"crossref","first-page":"31292","DOI":"10.3402\/jev.v5.31292","article-title":"Exosomal miRNAs as cancer biomarkers and therapeutic targets","volume":"5","author":"Thind","year":"2016","journal-title":"J. Extracell. Vesicles"},{"key":"10.1016\/j.parint.2020.102247_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002971","article-title":"Detection of circulating parasite-derived microRNAs in filarial infections","volume":"8","author":"Tritten","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.parint.2020.102247_bb0115","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.febslet.2015.02.005","article-title":"miR-10a controls glioma migration and invasion through regulating epithelial\u2013mesenchymal transition via EphA8","volume":"589","author":"Yan","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.parint.2020.102247_bb0120","first-page":"259","article-title":"Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells","volume":"34","author":"Zheng","year":"2016","journal-title":"Int. Immun."}],"container-title":["Parasitology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576920301975?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576920301975?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:32:45Z","timestamp":1761301965000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383576920301975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":24,"alternative-id":["S1383576920301975"],"URL":"https:\/\/doi.org\/10.1016\/j.parint.2020.102247","relation":{},"ISSN":["1383-5769"],"issn-type":[{"type":"print","value":"1383-5769"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of microRNAs expressed in the cystic legion of the liver of Mus musculus perorally infected with Echinococcus multilocularis Nemuro strain","name":"articletitle","label":"Article Title"},{"value":"Parasitology International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parint.2020.102247","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102247"}}