{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:39:01Z","timestamp":1761302341626,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parasitology International"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.parint.2020.102268","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T13:05:49Z","timestamp":1607605549000},"page":"102268","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["GRA12, a novel dense granule protein from Neospora caninum"],"prefix":"10.1016","volume":"81","author":[{"given":"Jingquan","family":"Dong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panpan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaocen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengtao","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xichen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.parint.2020.102268_bb0005","first-page":"326","article-title":"Neospora caninum in the dog: typical and atypical cases","volume":"65","author":"Van Ham","year":"1996","journal-title":"Vlaams Dierg. En. Tijds."},{"key":"10.1016\/j.parint.2020.102268_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0304-4017(96)01035-7","article-title":"A review of Neospora caninum and neosporosis","volume":"67","author":"Dubey","year":"1996","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.parint.2020.102268_bb0015","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/sky122","article-title":"Seroprevalence of Toxoplasma gondii and Neospora caninum infection in sheep, goats and fallow deer farmed on the same area","volume":"96","author":"Moskwa","year":"2018","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.parint.2020.102268_bb0020","first-page":"1","article-title":"Canine neosporosis","volume":"14","author":"Lindsay","year":"2000","journal-title":"J. Vet. Parasitol."},{"key":"10.1016\/j.parint.2020.102268_bb0025","doi-asserted-by":"crossref","first-page":"111","DOI":"10.17221\/5850-VETMED","article-title":"Toxoplasma gondii and Neospora caninum antibodies in goats in the Czech Republic","volume":"57","author":"Bartova","year":"2018","journal-title":"Vet. Med."},{"key":"10.1016\/j.parint.2020.102268_bb0030","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.actatropica.2017.10.029","article-title":"Molecular detection of Toxoplasma gondii and Neospora caninum in birds from South Africa","volume":"178","author":"Luk\u00e1\u0161ov\u00e1","year":"2018","journal-title":"Acta Trop."},{"key":"10.1016\/j.parint.2020.102268_bb0035","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.molbiopara.2016.01.007","article-title":"Vacuolar protein sorting mechanisms in Apicomplexan parasites","volume":"209","author":"Jimenez-Ruiz","year":"2016","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.parint.2020.102268_bb0040","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/BF00932560","article-title":"Exocytosis of Toxoplasma gondii dense granules into the parasitophorous vacuole after host cell invasion","volume":"76","author":"Leriche","year":"1990","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.parint.2020.102268_bb0045","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.bbrc.2015.02.078","article-title":"Toxoplasma gondii: Biochemical and biophysical characterization of recombinant soluble dense granule proteins GRA2 and GRA6","volume":"459","author":"Bittame","year":"2015","journal-title":"Biochem. Biophy. Res. Commun."},{"key":"10.1016\/j.parint.2020.102268_bb0050","first-page":"114","article-title":"Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts","volume":"73","author":"Carruthers","year":"1997","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.parint.2020.102268_bb0055","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0169-4758(94)90078-7","article-title":"Dense-granule organelles of Toxoplasma gondii: their role in the host parasite relationship","volume":"10","author":"Cesbron-Delauw","year":"1994","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.parint.2020.102268_bb0060","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1091\/mbc.e02-01-0021","article-title":"Biogenesis of nanotubular network in Toxoplasma parasitophorous vacuole induced by parasite proteins","volume":"13","author":"Mercier","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.parint.2020.102268_bb0065","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1093\/emboj\/20.12.3132","article-title":"Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole","volume":"20","author":"Hakansson","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.parint.2020.102268_bb0070","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01188-14","article-title":"Toxoplasma gondii ingests and digests host cytosolic proteins","volume":"5","author":"Dou","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.parint.2020.102268_bb0075","doi-asserted-by":"crossref","first-page":"4235","DOI":"10.1083\/jcb.201701108","article-title":"The parasite Toxoplasma sequesters diverse Rab host vesicles within an intravacuolar network","volume":"216","author":"Romano","year":"2017","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.parint.2020.102268_bb0080","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ijpara.2008.07.011","article-title":"GRA12, a Toxoplasma dense granule protein associated with the intravacuolar membranous nanotubular network","volume":"39","author":"Michelin","year":"2009","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.parint.2020.102268_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/abbs\/gmx010","article-title":"Identification and characterization of GRA6\/GRA7 of Neospora caninum in MDBK cells","volume":"49","author":"Dong","year":"2017","journal-title":"Acta Biochim. Biophys. Sin."},{"key":"10.1016\/j.parint.2020.102268_bb0090","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00589-19","article-title":"Toxoplasma gondii parasitophorous vacuole membrane-associated dense granule proteins orchestrate chronic infection and GRA12 underpins resistance to host gamma interferon","volume":"10","author":"Fox","year":"2019","journal-title":"mBio"}],"container-title":["Parasitology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138357692030218X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138357692030218X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:34:51Z","timestamp":1761302091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138357692030218X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":18,"alternative-id":["S138357692030218X"],"URL":"https:\/\/doi.org\/10.1016\/j.parint.2020.102268","relation":{},"ISSN":["1383-5769"],"issn-type":[{"type":"print","value":"1383-5769"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GRA12, a novel dense granule protein from Neospora caninum","name":"articletitle","label":"Article Title"},{"value":"Parasitology International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parint.2020.102268","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102268"}}