{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:29:08Z","timestamp":1791300548524,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parasitology International"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.parint.2021.102508","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T02:02:06Z","timestamp":1636682526000},"page":"102508","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Evaluation of the effectiveness of fluralaner against adult stages of Rhodnius prolixus in dogs"],"prefix":"10.1016","volume":"87","author":[{"given":"Antonio","family":"Ortega-Pacheco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anabel","family":"Poot-Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose I.","family":"Chan-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Guti\u00e9rrez-Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos M.","family":"Acevedo-Arcique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos M.","family":"Baak-Baak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Jim\u00e9nez-Coello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.parint.2021.102508_bb0005","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1603\/ME12242","article-title":"Identification of bloodmeal sources and Trypanosoma cruzi infection in triatomine bugs (Hemiptera: Reduviidae) from residential settings in Texas, the United States","volume":"50","author":"Kjos","year":"2013","journal-title":"J. Med. Entomol."},{"issue":"1","key":"10.1016\/j.parint.2021.102508_bb0010","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1017\/S0031182006001259","article-title":"Domestic dogs and cats as source of Trypanosoma cruzi infection in rural northwestern Argentina","volume":"134","author":"G\u00fcrtler","year":"2017","journal-title":"Parasitology"},{"issue":"1","key":"10.1016\/j.parint.2021.102508_bb0015","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/20477724.2020.1716558","article-title":"Identification of bloodmeal sources of triatomines captured in the Paraguayan Chaco region of South America by means of molecular biology analysis","volume":"114","author":"Fraenkel","year":"2020","journal-title":"Pathog. Glob. Health"},{"issue":"1","key":"10.1016\/j.parint.2021.102508_bb0020","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1590\/S0074-02761992000100011","article-title":"Experimental Chagas\u2019 disease in dogs","volume":"87","author":"Lana","year":"1992","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.parint.2021.102508_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.prevetmed.2020.105093","article-title":"Epidemiological and clinical characteristics of Trypanosoma cruzi infection in dogs (Canis lupus familiaris) from a Chagas disease-endemic urban area in Colombia","volume":"182","author":"Jaimes-Due\u00f1ez","year":"2020","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.parint.2021.102508_bb0030","series-title":"American Trypanosomiasis, Chagas Disease: One Hundred Years of Research","first-page":"223","article-title":"Control strategies against triatominae","author":"Gorla","year":"2017"},{"key":"10.1016\/j.parint.2021.102508_bb0035","article-title":"Residual survival and local dispersal drive reinfestation by Triatoma dimidiata following insecticide application in Guatemala","volume":"74","author":"Helms-Cahana","year":"2019","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.parint.2021.102508_bb0040","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/jmedent\/42.4.637","article-title":"High resistance to pyrethroid insecticides associated with ineffective field treatments in Triatoma infestans (Hemiptera: Reduviidae) from northern Argentina","volume":"42","author":"Picollo","year":"2005","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.parint.2021.102508_bb0045","first-page":"525","article-title":"The speed of kill of fluralaner (BravectoTM) against Ixodes ricinus ticks on dogs","volume":"7","author":"Wengenmayer","year":"2014","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.parint.2021.102508_bb0050","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/s13071-017-2278-2","article-title":"Systemic insecticide treatment of the canine reservoir of Trypanosoma cruzi induces high levels of lethality in Triatoma infestans, a principal vector of Chagas disease","volume":"10","author":"Loza","year":"2017","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.parint.2021.102508_bb0055","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.vetpar.2019.03.005","article-title":"An oral dose of Fluralaner administered to dogs kills pyrethroid-resistant and susceptible Chagas disease vectors for at least four months","volume":"268","author":"Lai\u00f1o","year":"2019","journal-title":"Vet. Parasitol."},{"issue":"101","key":"10.1016\/j.parint.2021.102508_bb0060","first-page":"159","article-title":"Determinaci\u00f3n de las reservas alimenticias en Triatoma infestans klug 1834 (Hemiptera, Reduviidae) en base a caracteres externos","volume":"41","author":"Montenegro","year":"1983","journal-title":"Physis"},{"key":"10.1016\/j.parint.2021.102508_bb0065","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.actatropica.2015.05.014","article-title":"Insecticide resistance in vector Chagas disease: evolution, mechanisms, and management","volume":"149","author":"Mougabure-Cueto","year":"2015","journal-title":"Acta Trop."},{"issue":"2","key":"10.1016\/j.parint.2021.102508_bb0070","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1089\/vbz.2018.2325","article-title":"Considering dogs as complementary targets of Chagas disease control","volume":"19","author":"Travi","year":"2019","journal-title":"Vector Borne Zoonotic Dis."},{"issue":"7","key":"10.1016\/j.parint.2021.102508_bb0075","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.trstmh.2004.11.013","article-title":"Chagas disease control: deltamethrin-treated collars reduce Triatoma infestans feeding success on dogs","volume":"99","author":"Reithinger","year":"2005","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"5","key":"10.1016\/j.parint.2021.102508_bb0080","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1590\/S0102-311X2004000500018","article-title":"Efficacy of Fipronil in the control of the peridomiciliary cycle of Triatoma infestans in an area resistant to deltamethrin","volume":"20","author":"Gentile","year":"2004","journal-title":"Cad Saude Publ."},{"issue":"3","key":"10.1016\/j.parint.2021.102508_bb0085","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.trstmh.2008.09.018","article-title":"Effects of topical application of fipronil spot-on on dogs against the Chagas disease vector Triatoma infestans","volume":"103","author":"G\u00fcrtler","year":"2009","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.parint.2021.102508_bb0090","series-title":"Efficacy of a Topical Combination of Fipronil-permethrin Against Rhodnius prolixus on Dogs","volume":"276","author":"Ucan-M\u00e9zquita","year":"2019"},{"key":"10.1016\/j.parint.2021.102508_bb0095","series-title":"Corrected Freedom of Information Summary, Original New Animal Drug Application, Bravecto (Fluralaner Chewable Tablets, Dogs)","first-page":"141","author":"FDA","year":"2014"},{"key":"10.1016\/j.parint.2021.102508_bb0100","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1756-3305-7-85","article-title":"Comparative pharmacokinetics of fluralaner in dogs and cats following single oral or intravenous administration","volume":"7","author":"Kilp","year":"2014","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.parint.2021.102508_bb0105","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s13071-015-1123-8","article-title":"Plasma pharmacokinetic profile of fluralaner (BravectoTM) and ivermectin following concurrent administration to dogs","volume":"8","author":"Walther","year":"2015","journal-title":"Parasit. Vectors"},{"issue":"1","key":"10.1016\/j.parint.2021.102508_bb0110","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.bbrc.2009.11.131","article-title":"The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels","volume":"391","author":"Ozoe","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.parint.2021.102508_bb0115","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1186\/s13071-016-1670-7","article-title":"Efficacy of fluralaner administered either orally or topically for the treatment of naturally acquired Sarcoptes scabiei var. canis infestation in dogs","volume":"9","author":"Taenzler","year":"2016","journal-title":"Parasit. Vectors"},{"issue":"1","key":"10.1016\/j.parint.2021.102508_bb0120","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1043-6618(02)00251-7","article-title":"Effects of liquid and freeze-dried grapefruit juice on the pharmacokinetics of praziquantel and its metabolite 4\u2032-hydroxy praziquantel in beagle dogs","volume":"47","author":"Giorgi","year":"2003","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.parint.2021.102508_bb0125","series-title":"Veterinary Pharmacology Therapeutics","first-page":"1035","article-title":"Antinematodal drugs","author":"Lanusse","year":"2018"},{"issue":"3\u20134","key":"10.1016\/j.parint.2021.102508_bb0130","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.vetpar.2007.06.028","article-title":"Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs","volume":"148","author":"Gokbulut","year":"2007","journal-title":"Vet. Parasitol."}],"container-title":["Parasitology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576921002269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383576921002269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T10:34:40Z","timestamp":1761302080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383576921002269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":26,"alternative-id":["S1383576921002269"],"URL":"https:\/\/doi.org\/10.1016\/j.parint.2021.102508","relation":{},"ISSN":["1383-5769"],"issn-type":[{"value":"1383-5769","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of the effectiveness of fluralaner against adult stages of Rhodnius prolixus in dogs","name":"articletitle","label":"Article Title"},{"value":"Parasitology International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parint.2021.102508","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102508"}}