{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T12:35:56Z","timestamp":1720874156508},"reference-count":29,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.parkreldis.2007.12.003","type":"journal-article","created":{"date-parts":[[2008,3,4]],"date-time":"2008-03-04T19:56:20Z","timestamp":1204660580000},"page":"569-571","source":"Crossref","is-referenced-by-count":14,"title":["Essential tremor and the common LRRK2 G2385R variant"],"prefix":"10.1016","volume":"14","author":[{"given":"Eng-King","family":"Tan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasinda","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Qin","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yih","family":"Yuen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.parkreldis.2007.12.003_bib1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/humu.20507","article-title":"Pathogenic mutations in Parkinson disease","volume":"28","author":"Tan","year":"2007","journal-title":"Hum Mutat"},{"issue":"3","key":"10.1016\/j.parkreldis.2007.12.003_bib2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s10048-006-0041-5","article-title":"A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan","volume":"7","author":"Di Fonzo","year":"2006","journal-title":"Neurogenetics"},{"issue":"6","key":"10.1016\/j.parkreldis.2007.12.003_bib3","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1007\/s00439-006-0268-0","article-title":"The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: genetic and functional evidence","volume":"120","author":"Tan","year":"2007","journal-title":"Hum Genet"},{"issue":"1","key":"10.1016\/j.parkreldis.2007.12.003_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1471-2377-6-47","article-title":"A common genetic factor for Parkinson disease in ethnic Chinese population in Taiwan","volume":"6","author":"Fung","year":"2006","journal-title":"BMC Neurol"},{"issue":"2","key":"10.1016\/j.parkreldis.2007.12.003_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.parkreldis.2006.12.001","article-title":"Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia","volume":"13","author":"Farrer","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"issue":"3","key":"10.1016\/j.parkreldis.2007.12.003_bib6","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/WNR.0b013e32801254b6","article-title":"A variation in LRRK2 is associated with Parkinson's disease in Asian population","volume":"18","author":"Funayama","year":"2007","journal-title":"Neuroreport"},{"issue":"5","key":"10.1016\/j.parkreldis.2007.12.003_bib7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1399-0004.2007.00890.x","article-title":"The role of common genetic risk variants in Parkinson disease","volume":"72","author":"Tan","year":"2007","journal-title":"Clin Genet"},{"key":"10.1016\/j.parkreldis.2007.12.003_bib8","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.neuron.2004.11.005","article-title":"Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology","volume":"44","author":"Zimprich","year":"2004","journal-title":"Neuron"},{"issue":"8","key":"10.1016\/j.parkreldis.2007.12.003_bib9","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1212\/01.wnl.0000180517.70572.37","article-title":"Analysis of LRRK2 functional domains in nondominant Parkinson disease","volume":"65","author":"Skipper","year":"2005","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.parkreldis.2007.12.003_bib10","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1001\/archneur.62.6.1004","article-title":"Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study","volume":"62","author":"Louis","year":"2005","journal-title":"Arch Neurol"},{"issue":"5","key":"10.1016\/j.parkreldis.2007.12.003_bib11","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1212\/WNL.54.5.1195","article-title":"Polymorphism of NACP-Rep1 in Parkinson's disease: an etiologic link with essential tremor?","volume":"54","author":"Tan","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2007.12.003_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/ana.410170404","article-title":"Association between essential tremor and Parkinson's disease","volume":"17","author":"Geraghty","year":"1985","journal-title":"Ann Neurol"},{"issue":"11","key":"10.1016\/j.parkreldis.2007.12.003_bib13","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1002\/mds.21584","article-title":"Increased risk of essential tremor in first-degree relatives of patients with Parkinson's disease","volume":"22","author":"Rocca","year":"2007","journal-title":"Mov Disord"},{"issue":"10","key":"10.1016\/j.parkreldis.2007.12.003_bib14","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1002\/mds.21383","article-title":"Prevalence of essential tremor in patients with Parkinson's disease vs. Parkinson-plus syndromes","volume":"22","author":"Louis","year":"2007","journal-title":"Mov Disord"},{"issue":"4","key":"10.1016\/j.parkreldis.2007.12.003_bib15","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1212\/WNL.45.4.645","article-title":"Tremor and longevity in relatives of patients with Parkinson's disease, essential tremor, and control subjects","volume":"45","author":"Jankovic","year":"1995","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.parkreldis.2007.12.003_bib16","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1212\/WNL.61.7.931","article-title":"Risk of action tremor in relatives of tremor-dominant and postural instability gait disorder PD","volume":"61","author":"Louis","year":"2003","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.parkreldis.2007.12.003_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.parkreldis.2006.05.033","article-title":"Exploring the relationship between essential tremor and Parkinson's disease","volume":"13","author":"Shahed","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.parkreldis.2007.12.003_bib18","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1212\/WNL.52.7.1422","article-title":"123I-IPT brain SPECT study in essential tremor and Parkinson's disease","volume":"52","author":"Lee","year":"1999","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.parkreldis.2007.12.003_bib19","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1212\/WNL.42.8.1554","article-title":"Isolated tremor and disruption of the nigrostriatal dopaminergic system: an 18F-dopa PET study","volume":"42","author":"Brooks","year":"1992","journal-title":"Neurology"},{"issue":"Suppl. 3","key":"10.1016\/j.parkreldis.2007.12.003_bib20","first-page":"2","article-title":"Consensus statement of the Movement Disorder Society on tremor","volume":"13","author":"Deuschl","year":"1998","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.parkreldis.2007.12.003_bib21","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/ng0997-84","article-title":"Mapping of a familial essential tremor gene, FET1, to chromosome 3q13","volume":"17","author":"Gulcher","year":"1997","journal-title":"Nat Genet"},{"issue":"6","key":"10.1016\/j.parkreldis.2007.12.003_bib22","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/mds.870120605","article-title":"A gene (ETM) for essential tremor maps to chromosome 2p22-p25","volume":"12","author":"Higgins","year":"1997","journal-title":"Mov Disord"},{"issue":"Pt 9","key":"10.1016\/j.parkreldis.2007.12.003_bib23","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1093\/brain\/awl120","article-title":"Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23","volume":"129","author":"Shatunov","year":"2006","journal-title":"Brain"},{"issue":"Pt 6","key":"10.1016\/j.parkreldis.2007.12.003_bib24","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1093\/brain\/awm018","article-title":"Genetics of essential tremor","volume":"130","author":"Deng","year":"2007","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.parkreldis.2007.12.003_bib25","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1212\/01.WNL.0000153481.30222.38","article-title":"A variant in the HS1-BP3 gene is associated with familial essential tremor","volume":"64","author":"Higgins","year":"2005","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/j.parkreldis.2007.12.003_bib26","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1212\/01.wnl.0000200984.10076.e5","article-title":"A variant in the HS1-BP3 gene is associated with familial essential tremor","volume":"65","author":"Shatunov","year":"2005","journal-title":"Neurology"},{"issue":"28","key":"10.1016\/j.parkreldis.2007.12.003_bib27","doi-asserted-by":"crossref","first-page":"10753","DOI":"10.1073\/pnas.0508189103","article-title":"A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor","volume":"103","author":"Jeanneteau","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.1016\/j.parkreldis.2007.12.003_bib28","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1212\/01.wnl.0000256773.87498.2f","article-title":"DRD3 variant and risk of essential tremor","volume":"68","author":"Tan","year":"2007","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.parkreldis.2007.12.003_bib29","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1212\/WNL.55.4.533","article-title":"Variability and validity of polymorphism association studies in Parkinson's disease","volume":"55","author":"Tan","year":"2000","journal-title":"Neurology"}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802008000217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802008000217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,31]],"date-time":"2018-12-31T08:53:44Z","timestamp":1546246424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802008000217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":29,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S1353802008000217"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2007.12.003","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}