{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:52:43Z","timestamp":1759693963137},"reference-count":12,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.parkreldis.2008.06.010","type":"journal-article","created":{"date-parts":[[2008,8,21]],"date-time":"2008-08-21T09:13:29Z","timestamp":1219310009000},"page":"321-323","source":"Crossref","is-referenced-by-count":14,"title":["Evaluation of SCN8A as a candidate gene for autosomal dominant essential tremor"],"prefix":"10.1016","volume":"15","author":[{"given":"Lisa M.","family":"Sharkey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie M.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Hedera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam H.","family":"Meisler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"11 Suppl. 4","key":"10.1016\/j.parkreldis.2008.06.010_bib1","first-page":"S21","article-title":"Essential tremor: clinical characteristics","volume":"54","author":"Jankovic","year":"2000","journal-title":"Neurology"},{"issue":"Pt 12","key":"10.1016\/j.parkreldis.2008.06.010_bib2","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1093\/brain\/awm266","article-title":"Neuropathological changes in essential tremor: 33 cases compared with 21 controls","volume":"130","author":"Louis","year":"2007","journal-title":"Brain"},{"issue":"Pt\u00a06","key":"10.1016\/j.parkreldis.2008.06.010_bib3","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1093\/brain\/awm018","article-title":"Genetics of essential tremor","volume":"130","author":"Deng","year":"2007","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.parkreldis.2008.06.010_bib4","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1002\/mds.21102","article-title":"Study of possible factors associated with age of onset in essential tremor","volume":"21","author":"Louis","year":"2006","journal-title":"Mov Disord"},{"issue":"9","key":"10.1016\/j.parkreldis.2008.06.010_bib5","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1002\/mds.20950","article-title":"Familial essential tremor with apparent autosomal dominant inheritance: should we also consider other inheritance modes?","volume":"21","author":"Ma","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.parkreldis.2008.06.010_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2007.11.002","article-title":"Reappraisal of the role of the DRD3 gene in essential tremor","author":"Blair","year":"2008","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"10.1016\/j.parkreldis.2008.06.010_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10709-004-1441-9","article-title":"Allelic mutations of the sodium channel SCN8A reveal multiple cellular and physiological functions","volume":"122","author":"Meisler","year":"2004","journal-title":"Genetica"},{"issue":"8","key":"10.1016\/j.parkreldis.2008.06.010_bib8","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1172\/JCI25466","article-title":"Sodium channel mutations in epilepsy and other neurological disorders","volume":"115","author":"Meisler","year":"2005","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.parkreldis.2008.06.010_bib9","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1136\/jmg.2005.035667","article-title":"Heterozygosity for a protein truncation mutation of sodium channel SCN8A in a patient with cerebellar atrophy, ataxia, and mental retardation","volume":"43","author":"Trudeau","year":"2006","journal-title":"J Med Genet"},{"issue":"3","key":"10.1016\/j.parkreldis.2008.06.010_bib10","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1172\/JCI200523625","article-title":"Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice","volume":"115","author":"Kralic","year":"2005","journal-title":"J Clin Invest"},{"issue":"1\u20132","key":"10.1016\/j.parkreldis.2008.06.010_bib11","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.neulet.2006.02.066","article-title":"Genetic analysis of the GABRA1 gene in patients with essential tremor","volume":"401","author":"Deng","year":"2006","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.parkreldis.2008.06.010_bib12","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/hmg\/ddl019","article-title":"Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2","volume":"15","author":"Kearney","year":"2006","journal-title":"Hum Mol Genet"}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802008001855?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802008001855?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T04:21:01Z","timestamp":1545798061000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802008001855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S1353802008001855"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2008.06.010","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}