{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T12:41:52Z","timestamp":1786365712327,"version":"build-2736575974"},"reference-count":26,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.parkreldis.2012.04.015","type":"journal-article","created":{"date-parts":[[2012,5,8]],"date-time":"2012-05-08T17:03:44Z","timestamp":1336496624000},"page":"854-858","source":"Crossref","is-referenced-by-count":26,"title":["Cognitive and olfactory deficits in Machado\u2013Joseph disease: A dopamine transporter study"],"prefix":"10.1016","volume":"18","author":[{"given":"Pedro","family":"Braga-Neto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre C.","family":"Felicio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Q.","family":"Hoexter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luiz","family":"Pedroso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edvia Almeida","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Alessi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00eds","family":"Minett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth F.","family":"Santos-Galduroz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ant\u00f4nio Jos\u00e9","family":"da Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas A.L.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Henrique F.","family":"Bertolucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo A.","family":"Bressan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orlando Graziani Povoas","family":"Barsottini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.parkreldis.2012.04.015_bib1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1474-4422(04)00737-9","article-title":"Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis","volume":"3","author":"Sch\u00f6ls","year":"2004","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.parkreldis.2011.02.004","article-title":"Clinical correlates of olfactory dysfunction in spinocerebellar ataxia type 3","volume":"17","author":"Braga-Neto","year":"2011","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1590\/S0004-282X1993000100004","article-title":"Machado Joseph disease of Azorean ancestry in Brazil: the Catarina kindred. Neurological, neuroimaging, psychiatric and neuropsychological findings in the largest known family, the Catarina kindred","volume":"51","author":"Radvany","year":"1993","journal-title":"Arq Neuropsiquiatr"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib4","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s12311-010-0183-8","article-title":"Neuropsychological features of patients with spinocerebellar ataxia (SCA) types 1, 2, 3, and 6","volume":"9","author":"Klinke","year":"2010","journal-title":"Cerebellum"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib5","volume":"vol. 6","author":"Braga-Neto","year":"2011"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib6","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/S1474-4422(10)70212-X","article-title":"Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease","volume":"9","author":"Kehagia","year":"2010","journal-title":"Lancet Neurol"},{"issue":"Suppl. 3","key":"10.1016\/j.parkreldis.2012.04.015_bib7","doi-asserted-by":"crossref","first-page":"S225","DOI":"10.1016\/S1353-8020(08)70006-3","article-title":"Olfaction in Parkinson's disease","volume":"13","author":"Doty","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib8","first-page":"1165","article-title":"Spinocerebellar ataxia type 2 olfactory impairment shows a pattern similar to other major neurodegenerative diseases","volume":"253","author":"Vel\u00e1zquez-P\u00e9rez","year":"2006","journal-title":"J\u00a0Neurol"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib9","first-page":"372","article-title":"[99mTc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent","volume":"24","author":"Kung","year":"1997","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib10","first-page":"994","article-title":"Decreased dopamine transporter binding in Machado-Joseph disease","volume":"41","author":"Yen","year":"2000","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib11","first-page":"153","article-title":"Dopamine transporter concentration is reduced in asymptomatic Machado-Joseph disease gene carriers","volume":"43","author":"Yen","year":"2002","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib12","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0022-510X(96)00242-0","article-title":"Positron emission tomography (PET) in Machado-Joseph disease","volume":"145","author":"Taniwaki","year":"1997","journal-title":"J\u00a0Neurol Sci"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib13","first-page":"308","article-title":"Striatal dopamine function in a family with multiple SCA-3 phenotypes","volume":"258","author":"Cubo","year":"2011","journal-title":"J\u00a0Neurol"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib14","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.parkreldis.2004.03.009","article-title":"The parkinsonian phenotype of spinocerebellar ataxia type 3 in a Taiwanese family","volume":"10","author":"Lu","year":"2004","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/WCO.0b013e3282f7673d","article-title":"New insights into the pathoanatomy of spinocerebellar ataxia type 3 (Machado-Joseph disease)","volume":"21","author":"Rub","year":"2008","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib16","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1212\/WNL.49.4.1133","article-title":"Fluorodopa and raclopride PET analysis of patients with Machado-Joseph disease","volume":"49","author":"Shinotoh","year":"1997","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib17","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1002\/mds.20978","article-title":"Spinocerebellar ataxia type 1, 2, and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography","volume":"21","author":"Reimold","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/mds.10571","article-title":"Dopamine transporter: basic aspects and neuroimaging","volume":"18","author":"Piccini","year":"2003","journal-title":"Mov Disord"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib19","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00006231-200505000-00005","article-title":"123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms","volume":"26","author":"Filippi","year":"2005","journal-title":"Nucl Med Commun"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib20","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nature09588","article-title":"A\u00a0selective role for dopamine in stimulus-reward learning","volume":"469","author":"Flagel","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib21","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.conb.2011.04.002","article-title":"Dopaminergic control of the striatum for high-level cognition","volume":"21","author":"Cools","year":"2011","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib22","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuropsychologia.2004.10.001","article-title":"Dopaminergic basis for deficits in working memory but not attentional set shifting in Parkinson\u2019s disease","volume":"43","author":"Lewis","year":"2005","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib23","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.cortex.2009.11.008","article-title":"Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing","volume":"46","author":"Stoodley","year":"2010","journal-title":"Cortex"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib24","doi-asserted-by":"crossref","first-page":"10266","DOI":"10.1523\/JNEUROSCI.2734-04.2004","article-title":"A\u00a0mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration","volume":"24","author":"Goti","year":"2004","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib25","doi-asserted-by":"crossref","first-page":"8990","DOI":"10.1523\/JNEUROSCI.18-21-08990.1998","article-title":"Odorant-induced and sniff-induced activation in the cerebellum of the human","volume":"18","author":"Sobel","year":"1998","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.parkreldis.2012.04.015_bib26","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1152\/jn.2000.84.3.1656","article-title":"Functional mapping of human brain in olfactory processing: a PET study","volume":"84","author":"Qureshy","year":"2000","journal-title":"J\u00a0Neurophysiol"}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802012001472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802012001472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T11:47:04Z","timestamp":1561722424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802012001472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S1353802012001472"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2012.04.015","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}