{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:15:14Z","timestamp":1790777714088,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health & Welfare, Republic of Korea","doi-asserted-by":"publisher","award":["HI14C0093"],"award-info":[{"award-number":["HI14C0093"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","prd-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.parkreldis.2016.06.020","type":"journal-article","created":{"date-parts":[[2016,7,3]],"date-time":"2016-07-03T04:09:04Z","timestamp":1467518944000},"page":"41-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Optic nerve integrity as a visuospatial cognitive predictor in Parkinson\u2019s disease"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6799-1564","authenticated-orcid":false,"given":"Jae Jung","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na-Young","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoonju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Koo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young H.","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil Hyu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.parkreldis.2016.06.020_bib1","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1093\/brain\/awh581","article-title":"Independent patterns of damage within magno-, parvo- and koniocellular pathways in Parkinson\u2019s disease","volume":"128","author":"Silva","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib2","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1212\/01.wnl.0000191565.11065.11","article-title":"Visual dysfunction in Parkinson disease without dementia","volume":"65","author":"Uc","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib3","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1212\/01.WNL.0000145764.70698.4E","article-title":"Visual perception in Parkinson disease dementia and dementia with Lewy bodies","volume":"63","author":"Mosimann","year":"2004","journal-title":"Neurology"},{"issue":"Pt 4","key":"10.1016\/j.parkreldis.2016.06.020_bib4","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/brain\/123.4.733","article-title":"Hallucinations in Parkinson\u2019s disease: prevalence, phenomenology and risk factors","volume":"123","author":"Fenelon","year":"2000","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib5","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.parkreldis.2015.04.005","article-title":"Structural and functional neuroimaging in patients with Parkinson\u2019s disease and visual hallucinations: a critical review","volume":"21","author":"Lenka","year":"2015","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib6","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1093\/brain\/awp068","article-title":"The retina in Parkinson\u2019s disease","volume":"132","author":"Archibald","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib7","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF02307822","article-title":"Functional neuroarchitecture of the retina: hypothesis on the dysfunction of retinal dopaminergic circuitry in Parkinson\u2019s disease","volume":"10","author":"Nguyen-Legros","year":"1988","journal-title":"Surg. Radiol. Anat."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib8","doi-asserted-by":"crossref","first-page":"e85718","DOI":"10.1371\/journal.pone.0085718","article-title":"Retinal nerve fiber layer thickness changes in Parkinson disease: a meta-analysis","volume":"9","author":"Yu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib9","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1001\/archneur.60.3.387","article-title":"Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study","volume":"60","author":"Aarsland","year":"2003","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1136\/jnnp.51.6.745","article-title":"The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson\u2019s disease","volume":"51","author":"Gibb","year":"1988","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib11","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1136\/jnnp.2005.073999","article-title":"Cardiac 123I-MIBG scintigraphy in patients with drug induced parkinsonism","volume":"77","author":"Lee","year":"2006","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib12","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.parkreldis.2013.10.024","article-title":"Olfactory performance acts as a cognitive reserve in non-demented patients with Parkinson\u2019s disease","volume":"20","author":"Lee","year":"2014","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4306\/pi.2011.8.4.348","article-title":"A\u00a0combination of the korean version of the mini-mental state examination and korean dementia screening questionnaire is a good screening tool for dementia in the elderly","volume":"8","author":"Shin","year":"2011","journal-title":"Psychiatry Investig."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0278-2626(92)90112-Y","article-title":"Quantitative and qualitative analyses of clock drawings in Alzheimer\u2019s and Huntington\u2019s disease","volume":"18","author":"Rouleau","year":"1992","journal-title":"Brain Cogn."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib15","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/gps.930100811","article-title":"A\u00a0comparison of clock and pentagon drawing in Alzheimer\u2019s disease","volume":"10","author":"Bourke","year":"1995","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib16","doi-asserted-by":"crossref","first-page":"399","DOI":"10.2967\/jnumed.111.095224","article-title":"Subregional patterns of preferential striatal dopamine transporter loss differ in Parkinson disease, progressive supranuclear palsy, and multiple-system atrophy","volume":"53","author":"Oh","year":"2012","journal-title":"J.\u00a0Nucl. Med."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib17","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.neuroimage.2005.11.051","article-title":"Optic nerve atrophy and retinal nerve fibre layer thinning following optic neuritis: evidence that axonal loss is a substrate of MRI-detected atrophy","volume":"31","author":"Trip","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib18","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.ajo.2013.09.028","article-title":"Distribution of retinal layer atrophy in patients with Parkinson disease and association with disease severity and duration","volume":"157","author":"Garcia-Martin","year":"2014","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib19","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.neuroimage.2003.07.005","article-title":"Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia","volume":"20","author":"Song","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib20","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1136\/bjophthalmol-2011-301280","article-title":"3-T Diffusion tensor imaging of the optic nerve in subjects with glaucoma: correlation with GDx-VCC, HRT-III and Stratus optical coherence tomography findings","volume":"96","author":"Nucci","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib21","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.neuroimage.2005.09.024","article-title":"Optic nerve diffusion tensor imaging in optic neuritis","volume":"30","author":"Trip","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib22","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.3174\/ajnr.A2574","article-title":"Diffusion tensor imaging of the optic nerve in multiple sclerosis: association with retinal damage and visual disability","volume":"32","author":"Smith","year":"2011","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib23","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/WNO.0000000000000240","article-title":"Correlation between structural and functional retinal changes in Parkinson disease","volume":"35","author":"Kaur","year":"2015","journal-title":"J.\u00a0Neuroophthalmol."},{"key":"10.1016\/j.parkreldis.2016.06.020_bib24","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/0028-3932(93)90135-M","article-title":"Visuospatial memory deficits at different stages of Parkinson\u2019s disease","volume":"31","author":"Owen","year":"1993","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib25","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1212\/WNL.0000000000000842","article-title":"Predictors of dementia in Parkinson disease: a prospective cohort study","volume":"83","author":"Anang","year":"2014","journal-title":"Neurology"},{"issue":"Pt 1","key":"10.1016\/j.parkreldis.2016.06.020_bib26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/brain\/122.1.111","article-title":"Visual control of locomotion in Parkinson\u2019s disease","volume":"122","author":"Azulay","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib27","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1093\/brain\/awm178","article-title":"Impaired navigation in drivers with Parkinson\u2019s disease","volume":"130","author":"Uc","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","article-title":"Staging of brain pathology related to sporadic Parkinson\u2019s disease","volume":"24","author":"Braak","year":"2003","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.parkreldis.2016.06.020_bib29","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1002\/mds.21083","article-title":"Correlation between cardiac 123I-MIBG and odor identification in patients with Parkinson\u2019s disease and multiple system atrophy","volume":"21","author":"Lee","year":"2006","journal-title":"Mov. Disord."}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802016302401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802016302401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T15:30:12Z","timestamp":1536593412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802016302401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":29,"alternative-id":["S1353802016302401"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2016.06.020","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optic nerve integrity as a visuospatial cognitive predictor in Parkinson\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2016.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}