{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:04:15Z","timestamp":1780106655631,"version":"3.54.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","prd-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism &amp; Related Disorders"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.parkreldis.2016.09.003","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T11:25:05Z","timestamp":1473420305000},"page":"87-93","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Excitatory Amino acid transporter expression in the essential tremor dentate nucleus and cerebellar cortex: A postmortem study"],"prefix":"10.1016","volume":"32","author":[{"given":"Jie","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3490-8514","authenticated-orcid":false,"given":"Geoffrey C.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0263-3341","authenticated-orcid":false,"given":"William J.","family":"Tate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Shi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7210-5851","authenticated-orcid":false,"given":"Jesus","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elan D.","family":"Louis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis L.","family":"Faust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Han","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.parkreldis.2016.09.003_bib1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/mds.870130105","article-title":"How common is the most common adult movement disorder? estimates of the prevalence of essential tremor throughout the world","volume":"13","author":"Louis","year":"1998","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib2","article-title":"Linking essential tremor to the cerebellum: physiological evidence","volume":"3","author":"Filip","year":"2015","journal-title":"Cerebellum"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib3","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1093\/brain\/awm266","article-title":"Neuropathological changes in essential tremor: 33 cases compared with 21 controls","volume":"130","author":"Louis","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib4","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1093\/brain\/awt238","article-title":"Purkinje cell axonal anatomy: quantifying morphometric changes in essential tremor versus control brains","volume":"136","author":"Babij","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib5","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1136\/jnnp.2010.213330","article-title":"Increased number of heterotopic Purkinje cells in essential tremor","volume":"82","author":"Kuo","year":"2011","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib6","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1093\/brain\/awu281","article-title":"Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum","volume":"137","author":"Lin","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib7","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1212\/WNL.0000000000001636","article-title":"Climbing fiber synaptic changes correlate with clinical features in essential tremor","volume":"84","author":"Louis","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib8","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/NEN.0b013e3181d1ad04","article-title":"Hairy baskets associated with degenerative Purkinje cell changes in essential tremor","volume":"69","author":"Erickson-Davis","year":"2010","journal-title":"J.\u00a0Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib9","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00401-013-1108-7","article-title":"Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau, Acta","volume":"125","author":"Kuo","year":"2013","journal-title":"Neuropathol"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/mds.26490","article-title":"Purkinje cell loss in essential tremor: random sampling quantification and nearest neighbor analysis","volume":"31","author":"Choe","year":"2016","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib11","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/mds.25845","article-title":"Essential tremor is not associated with cerebellar Purkinje cell loss","volume":"29","author":"Symanski","year":"2014","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib12","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.parkreldis.2012.01.013","article-title":"Essential tremor is not dependent upon cerebellar Purkinje cell loss","volume":"18","author":"Rajput","year":"2012","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib13","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1212\/WNL.0b013e31825fdeed","article-title":"Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor","volume":"79","author":"Thier","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib14","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1212\/WNL.0b013e31828f1903","article-title":"SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects","volume":"80","author":"Tan","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib15","article-title":"SLC1A2 variant is associated with essential tremor in Taiwanese population","volume":"8","author":"Yu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib16","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.neurobiolaging.2013.09.022","article-title":"SLC1A2 rs3794087 does not associate with essential tremor","volume":"35","author":"Ross","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib17","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ejphar.2003.08.073","article-title":"The glutamate and neutral amino acid transporter family: physiological and pharmacological implications","volume":"479","author":"Kanai","year":"2003","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib18","article-title":"Harmaline-induced tremor in mice: videotape documentation and open questions about the model","volume":"3","author":"Cheng","year":"2013","journal-title":"Tremor. Other. Hyperkinet. Mov. (New York)"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/s40478-014-0157-z","article-title":"Decreased EAAT2 protein expression in the essential tremor cerebellar cortex","volume":"2","author":"Lee","year":"2014","journal-title":"Acta. Neuropathol. Commun."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.nicl.2014.05.003","article-title":"Neuroimaging essentials in essential tremor: a systematic review","volume":"5","author":"Sharifi","year":"2014","journal-title":"Neuroimage. Clin."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib21","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s12311-009-0140-6","article-title":"Synaptic inhibition, excitation, and plasticity in neurons of the cerebellar nuclei","volume":"9","author":"Zheng","year":"2010","journal-title":"Cerebellum"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib22","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1080\/14734220601016080","article-title":"Rodent models of tremor","volume":"6","author":"Miwa","year":"2007","journal-title":"Cerebellum"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib23","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/S0306-4522(97)00252-2","article-title":"Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4","volume":"81","author":"Furuta","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib24","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.neuint.2011.05.008","article-title":"Short-term alterations in hippocampal glutamate transport system caused by one-single neonatal seizure episode: implications on behavioral performance in adulthood","volume":"59","author":"Moreira","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2010.11.085","article-title":"Differential molecular regulation of glutamate in kindling resistant rats","volume":"1375","author":"Doi","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.parkreldis.2016.09.003_bib26","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neuro.2013.07.002","article-title":"Elevated brain harmane (1-methyl-9H-pyrido[3,4-b]indole) in essential tremor cases vs","volume":"38","author":"Louis","year":"2013","journal-title":"controls, Neurotoxicology"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib27","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.neuropharm.2010.10.016","article-title":"Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression","volume":"60","author":"Li","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.parkreldis.2016.09.003_bib28","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/cne.10226","article-title":"Distribution of postsynaptic GABA(A) receptor aggregates in the deep cerebellar nuclei of normal and mutant mice","volume":"447","author":"Garin","year":"2002","journal-title":"J.\u00a0Comp. Neurol."}],"container-title":["Parkinsonism &amp; Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802016303285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802016303285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T13:22:29Z","timestamp":1536412949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802016303285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":28,"alternative-id":["S1353802016303285"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2016.09.003","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Excitatory Amino acid transporter expression in the essential tremor dentate nucleus and cerebellar cortex: A postmortem study","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2016.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}