{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:30:16Z","timestamp":1770748216079,"version":"3.49.0"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81371401"],"award-info":[{"award-number":["81371401"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology Planning Project of Guangdong","award":["81501112"],"award-info":[{"award-number":["81501112"]}]},{"name":"Science and Technology Planning Project of Guangdong","award":["2013B021800199"],"award-info":[{"award-number":["2013B021800199"]}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong","doi-asserted-by":"crossref","award":["S2012010009715"],"award-info":[{"award-number":["S2012010009715"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong","doi-asserted-by":"crossref","award":["S2013010014033"],"award-info":[{"award-number":["S2013010014033"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong","doi-asserted-by":"crossref","award":["2016A030310327"],"award-info":[{"award-number":["2016A030310327"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Program of Guangzhou","award":["2014J4100083"],"award-info":[{"award-number":["2014J4100083"]}]},{"name":"Science and Technology Program of Guangzhou","award":["2013J4100068"],"award-info":[{"award-number":["2013J4100068"]}]},{"name":"Medical Scientific Research Foundation of Guangdong Province","award":["A2014015"],"award-info":[{"award-number":["A2014015"]}]},{"name":"Science and Technology Program of Foshan","award":["2015AB00295"],"award-info":[{"award-number":["2015AB00295"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","prd-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.parkreldis.2017.06.020","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T06:02:01Z","timestamp":1498543321000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["The effects of striatal silent lacunar infarction on the substantia nigra and movement disorders in Parkinson's disease: A follow-up study"],"prefix":"10.1016","volume":"43","author":[{"given":"Guohua","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Nie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiqun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiancong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.parkreldis.2017.06.020_bib1","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1056\/NEJMoa022066","article-title":"Silent brain infarcts and the risk of dementia and cognitive decline","volume":"348","author":"Vermeer","year":"2003","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.bbi.2012.11.017","article-title":"Loss of substance P and inflammation precede delayed neurodegeneration in the substantia nigra after cerebral ischemia","volume":"29","author":"Rodriguez-Grande","year":"2013","journal-title":"Brain, Behav. Immun."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib3","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1002\/mrm.20508","article-title":"Diffusional kurtosis imaging: the quantification of non-Gaussian water diffusion by means of magnetic resonance imaging","volume":"53","author":"Jensen","year":"2005","journal-title":"Magn. Reson Med."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib4","first-page":"122","article-title":"Towards better MR characterization of neural tissues using directional diffusion kurtosis analysis","volume":"42","author":"Hui","year":"2008","journal-title":"Neuro-image"},{"key":"10.1016\/j.parkreldis.2017.06.020_bib5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1148\/radiol.11102277","article-title":"Parkinson disease: diagnostic utility of diffusion kurtosis imaging","volume":"261","author":"Wang","year":"2011","journal-title":"Radiology"},{"key":"10.1016\/j.parkreldis.2017.06.020_bib6","first-page":"5","article-title":"Diffusion kurtosis imaging of substantia nigra is a sensitive method for early diagnosis and disease evaluation in Parkinson's disease","author":"Zhang","year":"2015","journal-title":"Parkinson\u2019s Dis."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib7","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jocn.2016.03.032","article-title":"Striatal silent lacunar infarction is associated with changes to the substantia nigra in patients with early-stage Parkinson's disease: a diffusion kurtosis imaging study","volume":"33","author":"Zhang","year":"2016","journal-title":"J.\u00a0Clin. Neurosci."},{"issue":"5","key":"10.1016\/j.parkreldis.2017.06.020_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1212\/WNL.17.5.427","article-title":"Parkinsonism: onset, progression and mortality","volume":"17","author":"Hoehn","year":"1967","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.parkreldis.2017.06.020_bib9","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/mds.870090112","article-title":"Unified Parkinson's disease rating scale characteristics and structure: the Cooperative Multicentric Group","volume":"9","author":"Mart\u00ednez-Mart\u00edn","year":"1994","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib10","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw","year":"2013","journal-title":"Lancet Neurol."},{"issue":"16","key":"10.1016\/j.parkreldis.2017.06.020_bib11","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1212\/01.wnl.0000340982.01727.6e","article-title":"High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease","volume":"72","author":"Vaillancourt","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2017.06.020_bib12","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.parkreldis.2008.02.007","article-title":"Vascular pathology in patients with idiopathic Parkinson's disease","volume":"15","author":"Rektor","year":"2009","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.archger.2008.09.005","article-title":"The severity of leukoaraiosis correlates with the clinical phenotype of Parkinson's disease","volume":"49","author":"Lee","year":"2009","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib14","first-page":"276","article-title":"The influence of vascular risk factors and white matter hyperintensities on the degree of motor impairment in Parkinson's disease","volume":"40","author":"Derejko","year":"2006","journal-title":"Neurol. Neurochir. Pol."},{"issue":"1","key":"10.1016\/j.parkreldis.2017.06.020_bib15","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2169\/internalmedicine.49.2694","article-title":"Signal change of the substantia nigra on diffusion-weighted imaging following striatal infarction","volume":"49","author":"Nakajima","year":"2010","journal-title":"Intern Med."},{"key":"10.1016\/j.parkreldis.2017.06.020_bib16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.parkreldis.2013.04.006","article-title":"The effects of silent cerebral ischemic lesions on the prognosis of idiopathic Parkinson's disease","volume":"19","author":"Song","year":"2013","journal-title":"Park. Relat. Disord."}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802017302274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802017302274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T10:27:14Z","timestamp":1535711234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802017302274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":16,"alternative-id":["S1353802017302274"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2017.06.020","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of striatal silent lacunar infarction on the substantia nigra and movement disorders in Parkinson's disease: A follow-up study","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2017.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}