{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T04:22:37Z","timestamp":1794543757622,"version":"4.9.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","prd-journal.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.parkreldis.2018.01.006","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T08:04:37Z","timestamp":1515139477000},"page":"42-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["The contribution of gender differences in motor, behavioral and cognitive features to functional capacity, independence and quality of life in patients with Huntington's disease"],"prefix":"10.1016","volume":"49","author":[{"given":"Daniel","family":"Zielonka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"De Michele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymund A.C.","family":"Roos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinando","family":"Squitieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Rita","family":"Bentivoglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy T.","family":"Marcinkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Bernhard","family":"Landwehrmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.parkreldis.2018.01.006_bib1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.parkreldis.2014.12.013","article-title":"Update on Huntington's disease: advances in care and emerging therapeutic options","volume":"21","author":"Zielonka","year":"2015","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ng0893-393","article-title":"Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease","volume":"4","author":"Snell","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib3","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.parkreldis.2012.09.012","article-title":"The influence of gender on phenotype and disease progression in patients with Huntington's disease","volume":"19","author":"Zielonka","year":"2013","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib4","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/01.nmd.0000106004.67587.57","article-title":"Cognitive and psychiatric aspects of Huntington disease contribute to functional capacity","volume":"192","author":"Nehl","year":"2004","journal-title":"J.\u00a0Nerv. Ment. Dis."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib5","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1002\/mds.26012","article-title":"Determinants of functional disability in Huntington's disease: role of cognitive and motor dysfunction","volume":"29","author":"Ross","year":"2014","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib6","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/mds.22412","article-title":"Health-related quality of life in Huntington's disease: which factors matter most?","volume":"24","author":"Ho","year":"2009","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib7","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.parkreldis.2009.05.011","article-title":"Health related quality of life in early Parkinson's disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort","volume":"15","author":"Qin","year":"2009","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S1353-8020(01)00044-X","article-title":"Linking clinical variables to health-related quality of life in Parkinson's disease","volume":"8","author":"Chrischilles","year":"2002","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib9","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1212\/01.wnl.0000313835.33830.80","article-title":"Determinants of disability and quality of life in mild to moderate Parkinson disease","volume":"70","author":"Muslimovic","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2018.01.006_bib10","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.parkreldis.2014.06.001","article-title":"Quality of life in Parkinson's disease patients with motor fluctuations and dyskinesias in five European countries","volume":"20","author":"Hechtner","year":"2014","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib11","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.parkreldis.2013.07.010","article-title":"Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson's disease","volume":"19","author":"M\u00fcller","year":"2013","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.parkreldis.2010.08.012","article-title":"Determinants of health-related quality of life in Parkinson's disease: a systematic review","volume":"17","author":"Soh","year":"2011","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib13","first-page":"115","article-title":"Study protocol of registry e version 2.0-European Huntington's disease network (EHDN)","volume":"46","author":"Handley","year":"2011","journal-title":"Hygeia Public Health"},{"key":"10.1016\/j.parkreldis.2018.01.006_bib14","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/mds.870130609","article-title":"Unified Huntington's disease rating scale: a follow up","volume":"13","author":"Siesling","year":"1998","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib15","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/mds.23574","article-title":"An item response analysis of the motor and behavioral subscales of the unified Huntington's disease rating scale in Huntington disease gene expansion carriers","volume":"26","author":"Vaccarino","year":"2011","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib16","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1002\/mds.20208","article-title":"Health-related quality of life in Huntington's disease: a comparison of two generic instruments, SF-36 and SIP","volume":"19","author":"Ho","year":"2004","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib17","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/ana.410410521","article-title":"CAG repeat number governs the development rate of pathology in Huntington's disease","volume":"41","author":"Penney","year":"1997","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib18","first-page":"1533","article-title":"Fat-free mass and its predictors in Huntington's disease","volume":"262","author":"S\u00fcssmuth","year":"2015","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib19","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/00005053-199303000-00008","article-title":"Cognitive and motor correlates of everyday functioning in early Huntington's disease","volume":"181","author":"Rothlind","year":"1993","journal-title":"J.\u00a0Nerv. Ment. Dis."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib20","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/mds.1097","article-title":"Quantitative assessment of daytime motor activity provides a responsive measure of functional decline in patients with Huntington's disease","volume":"16","author":"van Vugt","year":"2001","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib21","first-page":"2080","article-title":"Progression of motor subtypes in Huntington's disease: a 6-year follow-up study","volume":"263","author":"Jacobs","year":"2016","journal-title":"J.\u00a0Neurol."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/mds.870080212","article-title":"Assessment of adaptive functioning in Huntington's disease","volume":"8","author":"Bylsma","year":"1993","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib23","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1212\/WNL.54.2.452","article-title":"Rate of functional decline in Huntington's disease","volume":"54","author":"Marder","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2018.01.006_bib24","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1002\/mds.22953","article-title":"Cognitive and functional decline in Huntington's disease: dementia criteria revisited","volume":"25","author":"Peavy","year":"2010","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib25","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1212\/01.WNL.0000086373.32347.16","article-title":"Huntington's disease: clinical correlates of disability and progression","volume":"61","author":"Mahant","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.parkreldis.2018.01.006_bib26","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1002\/mds.25422","article-title":"Better global and cognitive functioning in choreatic versus hypokinetic-rigid Huntington's disease","volume":"28","author":"Hart","year":"2013","journal-title":"Mov. Disord."},{"key":"10.1016\/j.parkreldis.2018.01.006_bib27","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1136\/jnnp-2013-307343","article-title":"Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)","volume":"85","author":"van Duijn","year":"2014","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatr."}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802018300063?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802018300063?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T22:41:23Z","timestamp":1545259283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802018300063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":27,"alternative-id":["S1353802018300063"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2018.01.006","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The contribution of gender differences in motor, behavioral and cognitive features to functional capacity, independence and quality of life in patients with Huntington's disease","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2018.01.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}