{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:13:14Z","timestamp":1793459594795,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Victorian Department of Health and Human Services"},{"DOI":"10.13039\/100008718","name":"Mason Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008718","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian National Health & Medical Research Council"},{"name":"Australian National Health & Medical Research Council"},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian National Health & Medical Research Council"},{"name":"National Institute of Aging"},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian National Health & Medical Research Council"},{"name":"UCB Australia"},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian National Health & Medical Research Council"},{"name":"Operational Infrastructure Support Victorian State Government"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","prd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.parkreldis.2018.10.026","type":"journal-article","created":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T14:25:21Z","timestamp":1540304721000},"page":"198-202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Parkinson's disease prevalence and the association with rurality and agricultural determinants"],"prefix":"10.1016","volume":"61","author":[{"given":"Darshini","family":"Ayton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3479-2427","authenticated-orcid":false,"given":"Scott","family":"Ayton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna L.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley I.","family":"Bush","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2623-4078","authenticated-orcid":false,"given":"Narelle","family":"Warren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.parkreldis.2018.10.026_bib1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1212\/01.WNL.0000113727.73153.68","article-title":"Incidence of Parkinson disease and parkinsonism in three elderly populations of central Spain","volume":"62","author":"Benito-Leon","year":"2004","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.parkreldis.2018.10.026_bib2","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/aje\/kwg068","article-title":"Incidence of Parkinson's disease: variation by age, gender, and race\/ethnicity","volume":"157","author":"Van Den Eeden","year":"2003","journal-title":"Am. J. Epidemiol."},{"issue":"4","key":"10.1016\/j.parkreldis.2018.10.026_bib3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.euroneuro.2005.04.007","article-title":"Prevalence and incidence of Parkinson's disease in Europe","volume":"15","author":"von Campenhausen","year":"2005","journal-title":"Eur. Neuropsychopharmacol.: J. Europ. College Neuropsychopharmacol."},{"issue":"2","key":"10.1016\/j.parkreldis.2018.10.026_bib4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1016-3190(10)60044-4","article-title":"The Epidemiology of Parkinson's disease","volume":"22","author":"Chen","year":"2010","journal-title":"Tzu Chi Med. J."},{"key":"10.1016\/j.parkreldis.2018.10.026_bib5","series-title":"Australia's Health 2012","author":"Australian Institute of Health and Welfare","year":"2012"},{"issue":"6","key":"10.1016\/j.parkreldis.2018.10.026_bib6","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1159\/000026185","article-title":"The epidemiology of Parkinson's disease in an Australian population","volume":"17","author":"McCann","year":"1998","journal-title":"Neuroepidemiology"},{"issue":"3","key":"10.1016\/j.parkreldis.2018.10.026_bib7","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jocn.2005.04.015","article-title":"Prevalence of Parkinson's disease in metropolitan and rural Queensland: a general practice survey","volume":"13","author":"Peters","year":"2006","journal-title":"J. Clin. Neurosci.: Off. J. Neurosurg. Soc. Australasia"},{"issue":"12","key":"10.1016\/j.parkreldis.2018.10.026_bib8","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1212\/WNL.45.12.2143","article-title":"Prevalence of Parkinson's disease in the elderly: the rotterdam study","volume":"45","author":"de Rijk","year":"1995","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.parkreldis.2018.10.026_bib9","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/ajim.20494","article-title":"High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries","volume":"50","author":"Lucchini","year":"2007","journal-title":"Am. J. Ind. Med."},{"issue":"8","key":"10.1016\/j.parkreldis.2018.10.026_bib10","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1111\/j.1468-1331.2012.03683.x","article-title":"Incidence and prevalence of Parkinson's disease in buenos aires city, Argentina","volume":"19","author":"Bauso","year":"2012","journal-title":"Eur. J. Neurol.: Off. J. Europ. Feder. Neurol. Soc."},{"issue":"10","key":"10.1016\/j.parkreldis.2018.10.026_bib11","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.clineuro.2009.08.010","article-title":"Prevalence of Parkinson's disease in northern Jordan","volume":"111","author":"Alrefai","year":"2009","journal-title":"Clin. Neurol. Neurosurg."},{"issue":"6","key":"10.1016\/j.parkreldis.2018.10.026_bib12","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","article-title":"Epidemiology of Parkinson's disease","volume":"5","author":"de Lau","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.parkreldis.2018.10.026_bib13","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.envint.2012.05.004","article-title":"Occupational exposure to pesticides and Parkinson's disease: a systematic review and meta-analysis of cohort studies","volume":"46","author":"Van Maele-Fabry","year":"2012","journal-title":"Environ. Int."},{"key":"10.1016\/j.parkreldis.2018.10.026_bib14","series-title":"Census of Population and Housing","author":"Australian Bureau of Statistics","year":"2011"},{"key":"10.1016\/j.parkreldis.2018.10.026_bib15","series-title":"Rural, Regional and Remote Health: a Guide to Remoteness Classifications","author":"Australian Institute of Health and Welfare","year":"2004"},{"key":"10.1016\/j.parkreldis.2018.10.026_bib16","series-title":"Agricultural Commodities, Australia","author":"Australian Bureau of Statistics","year":"2010"},{"issue":"3","key":"10.1016\/j.parkreldis.2018.10.026_bib17","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.taap.2011.05.006","article-title":"Association between environmental exposure to pesticides and neurodegenerative diseases","volume":"256","author":"Parron","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.parkreldis.2018.10.026_bib18","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/ije\/29.2.323","article-title":"Parkinson's disease mortality and pesticide exposure in California 1984-1994","volume":"29","author":"Ritz","year":"2000","journal-title":"Int. J. Epidemiol."},{"issue":"32","key":"10.1016\/j.parkreldis.2018.10.026_bib19","first-page":"303","article-title":"Parkinson's disease and pesticides exposure: new findings from a comprehensive study in Nebraska, USA","volume":"3","author":"Wan","year":"2015","journal-title":"J. Rural Health: Off. J. Am. Rural Heal. Assoc. Nat. Rural Heal. Care Assoc."},{"issue":"1","key":"10.1016\/j.parkreldis.2018.10.026_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/mds.870090111","article-title":"A case-control study of Parkinson's disease in a horticultural region of British Columbia","volume":"9","author":"Hertzman","year":"1994","journal-title":"Mov. Disord.: Off. J. Movement Disord. Soc."},{"issue":"12","key":"10.1016\/j.parkreldis.2018.10.026_bib21","doi-asserted-by":"crossref","first-page":"4022","DOI":"10.1016\/j.bmc.2009.01.046","article-title":"Natural products in crop protection","volume":"17","author":"Dayan","year":"2009","journal-title":"Bioorg. Med. Chem."},{"issue":"4","key":"10.1016\/j.parkreldis.2018.10.026_bib22","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1007\/BF02866548","article-title":"The diverse uses of fish-poison plants in Northwest Guyana","volume":"54","author":"Van Andel","year":"2000","journal-title":"Econ. Bot."},{"key":"10.1016\/j.parkreldis.2018.10.026_bib23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0035-9203(38)90078-1","article-title":"Suicide by ingestion of derris root sp. in New Ireland","volume":"32","author":"Holland","year":"1938","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"3","key":"10.1016\/j.parkreldis.2018.10.026_bib24","doi-asserted-by":"crossref","first-page":"R280","DOI":"10.1186\/cc3528","article-title":"Fatality after deliberate ingestion of the pesticide rotenone: a case report","volume":"9","author":"Wood","year":"2005","journal-title":"Crit. Care"},{"issue":"12","key":"10.1016\/j.parkreldis.2018.10.026_bib25","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/81834","article-title":"Chronic systemic pesticide exposure reproduces features of Parkinson's disease","volume":"3","author":"Betarbet","year":"2000","journal-title":"Nat. Neurosci."},{"issue":"6","key":"10.1016\/j.parkreldis.2018.10.026_bib26","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1289\/ehp.1002839","article-title":"Rotenone, paraquat, and Parkinson's disease","volume":"119","author":"Tanner","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.parkreldis.2018.10.026_bib27","series-title":"Biotechnology","author":"Pal","year":"2007"},{"issue":"2","key":"10.1016\/j.parkreldis.2018.10.026_bib28","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3923\/biotech.2005.79.93","article-title":"Useful metabolites from plant tissue cultures","volume":"4","author":"Sarin","year":"2005","journal-title":"Biotechnology"},{"key":"10.1016\/j.parkreldis.2018.10.026_bib29","series-title":"Anonymous. Living with Parkinson's Disease","year":"2007"},{"issue":"4","key":"10.1016\/j.parkreldis.2018.10.026_bib30","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1159\/000445751","article-title":"The incidence of Parkinson's disease: a systematic review and meta-analysis","volume":"46","author":"Hirsch","year":"2016","journal-title":"Neuroepidemiology"},{"issue":"5","key":"10.1016\/j.parkreldis.2018.10.026_bib31","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/mds.20041","article-title":"Drug adherence in Parkinson's disease","volume":"19","author":"Leopold","year":"2004","journal-title":"Movement Disord.: Off. J. Movement Disord. Soc."}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802018304620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802018304620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:16:18Z","timestamp":1761178578000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802018304620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":31,"alternative-id":["S1353802018304620"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2018.10.026","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Parkinson's disease prevalence and the association with rurality and agricultural determinants","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2018.10.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}