{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:04:15Z","timestamp":1780106655584,"version":"3.54.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000263","name":"Parkinson Society Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000196","name":"Canada Foundation for Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009408","name":"Fondation Brain Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009408","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000243","name":"W. Garfield Weston Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000864","name":"Michael J. Fox Foundation for Parkinson's Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000864","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005339","name":"American Academy of Neurology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005339","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008021","name":"Bristol-Myers Squibb Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001262","name":"National Parkinson Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012214","name":"Oak Tree Philanthropic Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012214","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004313","name":"General Electric","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004313","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008476","name":"University of California, Irvine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008476","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009655","name":"Sunovion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008440","name":"International Parkinson and Movement Disorder Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008914","name":"Ontario Brain Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008914","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000864","name":"Michael J. Fox Foundation for Parkinson's Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000864","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012479","name":"Weston Brain Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000241","name":"Physicians' Services Incorporated Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007880","name":"Johns Hopkins University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007880","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012531","name":"Dystonia Medical Research Foundation Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012531","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","prd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Parkinsonism & Related Disorders"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.parkreldis.2019.06.007","type":"journal-article","created":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T02:01:27Z","timestamp":1559959287000},"page":"165-171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["The clinical significance of lower limb tremors"],"prefix":"10.1016","volume":"65","author":[{"given":"Rajasumi","family":"Rajalingam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Breen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8371-8629","authenticated-orcid":false,"given":"Robert","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine V.","family":"Kalia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato P.","family":"Munhoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Slow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio P.","family":"Strafella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony E.","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5346-0180","authenticated-orcid":false,"given":"Alfonso","family":"Fasano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.parkreldis.2019.06.007_bib1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/mds.27121","article-title":"Tremor task force of the international Parkinson and movement disorder society, consensus statement on the classification of tremors, from the task force on tremor of the international Parkinson and movement disorder society","volume":"33","author":"Bhatia","year":"2018","journal-title":"Mov. Disord."},{"issue":"2","key":"10.1016\/j.parkreldis.2019.06.007_bib2","first-page":"167","article-title":"The long-term outcome of orthostatic tremor","volume":"87","author":"Ganos","year":"2016","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"14","key":"10.1016\/j.parkreldis.2019.06.007_bib3","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1002\/mds.22755","article-title":"Essential tremor \u2013 neurodegenerative or nondegenerative disease towards a working definition of ET","volume":"24","author":"Deuschl","year":"2009","journal-title":"Mov. Disord."},{"issue":"8","key":"10.1016\/j.parkreldis.2019.06.007_bib4","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.parkreldis.2008.11.006","article-title":"Action tremor of the legs in essential tremor: prevalence, clinical correlates, and comparison with age-matched controls","volume":"15","author":"Poston","year":"2009","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2019.06.007_bib5","series-title":"Parkinson's Disease and Movement Disorders","first-page":"271","article-title":"Clinical rating scale for tremor","author":"Fahn","year":"1993"},{"issue":"13","key":"10.1016\/j.parkreldis.2019.06.007_bib6","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1002\/mds.25648","article-title":"Task force report: scales for screening and evaluating tremor: critique and recommendations","volume":"28","author":"Elble","year":"2013","journal-title":"Mov. Disord."},{"issue":"144","key":"10.1016\/j.parkreldis.2019.06.007_bib7","first-page":"1","article-title":"Essential tremor: a clinical and genetic population study","volume":"36","author":"Larsson","year":"1960","journal-title":"Acta Psychiatr. Scand. Suppl."},{"issue":"2","key":"10.1016\/j.parkreldis.2019.06.007_bib8","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1212\/WNL.41.2_Part_1.234","article-title":"Essential tremor: clinical correlates in 350 patients","volume":"41","author":"Lou","year":"1991","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.parkreldis.2019.06.007_bib9","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1002\/mds.26383","article-title":"Therapeutic advances in tremor","volume":"30","author":"Fasano","year":"2015","journal-title":"Mov. Disord."},{"issue":"5","key":"10.1016\/j.parkreldis.2019.06.007_bib10","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1111\/j.1468-1331.2011.03626.x","article-title":"Surgical therapy for multiple sclerosis tremor: a 12-year follow-up study","volume":"19","author":"Hassan","year":"2012","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.parkreldis.2019.06.007_bib11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/B978-0-12-801772-2.00019-9","article-title":"Functional tremor","volume":"139","author":"Schwingenschuh","year":"2016","journal-title":"Handb. Clin. Neurol."},{"issue":"Pt 6","key":"10.1016\/j.parkreldis.2019.06.007_bib12","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1093\/brain\/awg142","article-title":"Parkin disease: a phenotypic study of a large case series","volume":"126","author":"Khan","year":"2003","journal-title":"Brain"},{"issue":"Suppl 1","key":"10.1016\/j.parkreldis.2019.06.007_bib13","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1016\/j.parkreldis.2017.07.006","article-title":"The overlap between Essential tremor and Parkinson disease","volume":"46","author":"Algarni","year":"2018","journal-title":"Park. Relat. Disord."},{"key":"10.1016\/j.parkreldis.2019.06.007_bib14","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.parkreldis.2018.06.029","article-title":"Essential tremor plus is more common than essential tremor: insights from the reclassification of a cohort of patients with lower limb tremor","volume":"56","author":"Rajalingam","year":"2018","journal-title":"Park. Relat. Disord."}],"container-title":["Parkinsonism & Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802019302688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1353802019302688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T19:14:25Z","timestamp":1762370065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1353802019302688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":14,"alternative-id":["S1353802019302688"],"URL":"https:\/\/doi.org\/10.1016\/j.parkreldis.2019.06.007","relation":{},"ISSN":["1353-8020"],"issn-type":[{"value":"1353-8020","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The clinical significance of lower limb tremors","name":"articletitle","label":"Article Title"},{"value":"Parkinsonism & Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.parkreldis.2019.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}