{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:55:43Z","timestamp":1766048143981},"reference-count":26,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathologie Biologie"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.patbio.2009.04.006","type":"journal-article","created":{"date-parts":[[2009,5,29]],"date-time":"2009-05-29T17:15:40Z","timestamp":1243617340000},"page":"137-141","source":"Crossref","is-referenced-by-count":13,"title":["Immunohistochemical analysis of vascular endothelial growth factor (VEGF) and p53 expression in pterygium from Tunisian patients"],"prefix":"10.1016","volume":"59","author":[{"given":"T.","family":"Khalfaoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Mkannez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Colin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Imen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Zbiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Errais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Anane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Beltaief","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Zhioua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ben Hamida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Lizard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ouertani-Meddeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.patbio.2009.04.006_bib1","series-title":"Principles and practice of ophthalmic plastic and reconstructive surgery","first-page":"206","article-title":"Management of pterygia","author":"Deitch","year":"1996"},{"key":"10.1016\/j.patbio.2009.04.006_bib2","first-page":"33","article-title":"Pt\u00e9rygion","volume":"13","author":"Cornand","year":"1990","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib3","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s004170050263","article-title":"Pterygium with bulbar conjunctival hemorrhages","volume":"237","author":"Kria","year":"1999","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib4","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1007\/s004170050144","article-title":"Growth factors in cultured pterygium fibroblasts: immunohistochemical, ELISA analysis","volume":"236","author":"Kria","year":"1998","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib5","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1076\/ceyr.17.10.986.5245","article-title":"TNP-470 (a fungus-derived inhibitor of angiogenesis) reduces proliferation of cultured fibroblasts isolated from primary pterygia: a possible drug therapy for pterygia","volume":"17","author":"Kria","year":"1998","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.patbio.2009.04.006_bib6","first-page":"59","article-title":"VEGF and tumor angiogenesis","volume":"18","author":"Quart","year":"2001","journal-title":"J Biol Med"},{"key":"10.1016\/j.patbio.2009.04.006_bib7","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1159\/000268033","article-title":"Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications of therapies","volume":"29","author":"Aiello","year":"1997","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.patbio.2009.04.006_bib8","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0002-9394(14)70868-2","article-title":"Factors controlling angiogenesis","volume":"124","author":"Casey","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1046\/j.1463-1318.2001.00194.x","article-title":"Relationship of angiogenesis and p53 protein expression in colorectal carcinomas","volume":"3","author":"Sarioglu","year":"2001","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.patbio.2009.04.006_bib10","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/00001622-200201000-00015","article-title":"Multiple roles of the tumor suppressor p53","volume":"14","author":"Bargonetti","year":"2002","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.patbio.2009.04.006_bib11","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1076\/ceyr.16.12.1179.5036","article-title":"P53 expression in altered limbal basal cells of pinguecula, pterygia and limbal tumors","volume":"16","author":"Dushku","year":"1997","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.patbio.2009.04.006_bib12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1076\/ceyr.24.2.105.8166","article-title":"p53 immunoreactivity, Ki-67 expression and microcirculation patterns in melanoma of the iris, ciliary body and choroid","volume":"24","author":"Chowers","year":"2002","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.patbio.2009.04.006_bib13","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1001\/archopht.116.11.1476","article-title":"Leucocyte adhesion molecule expression in scleritis","volume":"116","author":"Sangwan","year":"1998","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib14","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1001\/archopht.1996.01100140179011","article-title":"Localization of vascular endothelial growth factor in human retina and choroid","volume":"114","author":"Lutty","year":"1996","journal-title":"Arch ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib15","first-page":"2115","article-title":"Constitutive expression of VEGF, VEGFR-1, VEGFR-2 in normal eyes","volume":"40","author":"Kim","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.patbio.2009.04.006_bib16","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1097\/00003226-200110000-00013","article-title":"Expression of vascular endothelial growth and inducible nitric oxide synthetase in pterygia","volume":"20","author":"Lee","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.patbio.2009.04.006_bib17","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1076\/ceyr.25.1.17.9959","article-title":"Angiogenesis in pterygium: morphometric and immunohistochemical study","volume":"25","author":"Marcovich","year":"2002","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.patbio.2009.04.006_bib18","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00417-002-0589-1","article-title":"Connective tissue growth factor in pterygium: simultaneous presence with vascular endothelial growth factor\u00a0\u2013\u00a0possible contributing factor to conjunctival scarring","volume":"241","author":"Van Setten","year":"2003","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib19","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0002-9394(14)70141-2","article-title":"Abnormal expression of p53 tumor suppressor gene in the conjunctiva of patients with pterygium","volume":"123","author":"Tan","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib20","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/S0161-6420(00)00651-5","article-title":"Proliferative activity and p53 expression in primary and recurrent pterygia","volume":"108","author":"Chowers","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.patbio.2009.04.006_bib21","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/sj.eye.6700150","article-title":"Overexpression of p53 tumor suppressor gene in pterygia","volume":"1","author":"Weinstein","year":"2002","journal-title":"Eye"},{"key":"10.1016\/j.patbio.2009.04.006_bib22","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1177\/112067219800800307","article-title":"Expression of p53 protein in pterygia","volume":"8","author":"Onur","year":"1998","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1078\/0065-1281-00584","article-title":"Immunohistochemical study of p53, p21 and PCNA in pterygium","volume":"103","author":"Ueda","year":"2001","journal-title":"Acta Histochem"},{"key":"10.1016\/j.patbio.2009.04.006_bib24","first-page":"1157","article-title":"Expression of p53 protein is an early event in ultraviolet light-induced cutaneous squamous cell carcinogenesis","volume":"129","author":"Nagano","year":"1994","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.patbio.2009.04.006_bib25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1046\/j.1442-2050.2003.00309.x","article-title":"Prognostic value of p53 protein expression and vascular endothelial growth factor expression in resected squamous cell carcinoma of the oesophagus","volume":"16","author":"Rosa","year":"2003","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.patbio.2009.04.006_bib26","first-page":"963","article-title":"Mutant p53 potentiates protein kinase C induction of VEGF","volume":"9","author":"Kieser","year":"1994","journal-title":"Oncogene"}],"container-title":["Pathologie Biologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0369811409000467?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0369811409000467?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T12:46:08Z","timestamp":1558356368000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0369811409000467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0369811409000467"],"URL":"https:\/\/doi.org\/10.1016\/j.patbio.2009.04.006","relation":{},"ISSN":["0369-8114"],"issn-type":[{"value":"0369-8114","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}