{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:27:02Z","timestamp":1785547622665,"version":"3.56.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","surgpath.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Surgical Pathology Clinics"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.path.2022.07.001","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T06:59:57Z","timestamp":1665644397000},"page":"591-608","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cribriform Lesions of the Prostate Gland"],"prefix":"10.1016","volume":"15","author":[{"given":"Qi","family":"Cai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajal B.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib1","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/PAS.0000000000000530","article-title":"The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma: definition of grading patterns and proposal for a new grading system","volume":"40","author":"Epstein","year":"2016","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.path.2022.07.001_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.humpath.2021.09.005","article-title":"Prognostic value of cribriform size, percentage, and intraductal carcinoma in Gleason Score 7 prostate cancer with Cribriform Gleason Pattern 4","author":"Chen","year":"2021","journal-title":"Hum Pathol"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/s41379-018-0157-9","article-title":"Large cribriform growth pattern identifies ISUP grade 2 prostate cancer at high risk for recurrence and metastasis","volume":"32","author":"Hollemans","year":"2019","journal-title":"Mod Pathol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s00428-015-1809-5","article-title":"Cribriform morphology predicts upstaging after radical prostatectomy in patients with Gleason score 3 + 4 = 7 prostate cancer at transrectal ultrasound (TRUS)-guided needle biopsy","volume":"467","author":"Keefe","year":"2015","journal-title":"Virchows Arch"},{"issue":"6","key":"10.1016\/j.path.2022.07.001_bib5","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/modpathol.2016.49","article-title":"Disease-specific survival of patients with invasive cribriform and intraductal prostate cancer at diagnostic biopsy","volume":"29","author":"Kweldam","year":"2016","journal-title":"Mod Pathol"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib6","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/modpathol.2014.116","article-title":"Cribriform growth is highly predictive for postoperative metastasis and disease-specific death in Gleason score 7 prostate cancer","volume":"28","author":"Kweldam","year":"2015","journal-title":"Mod Pathol"},{"key":"10.1016\/j.path.2022.07.001_bib7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejca.2016.07.012","article-title":"Prostate cancer outcomes of men with biopsy Gleason score 6 and 7 without cribriform or intraductal carcinoma","volume":"66","author":"Kweldam","year":"2016","journal-title":"Eur J Cancer"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib8","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/s41379-020-0625-x","article-title":"Cribriform architecture in radical prostatectomies predicts oncological outcome in Gleason score 8 prostate cancer patients","volume":"34","author":"Hollemans","year":"2021","journal-title":"Mod Pathol"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.eururo.2019.07.051","article-title":"Improved prostate cancer biopsy grading by incorporation of invasive cribriform and intraductal carcinoma in the 2014 grade groups","volume":"77","author":"van Leenders","year":"2020","journal-title":"Eur Urol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib10","doi-asserted-by":"crossref","first-page":"461","DOI":"10.5858\/arpa.2020-0015-RA","article-title":"The 2019 genitourinary pathology society (GUPS) white paper on contemporary grading of prostate cancer","volume":"145","author":"Epstein","year":"2021","journal-title":"Arch Pathol Lab Med"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib11","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1097\/PAS.0000000000001497","article-title":"The 2019 international society of urological pathology (ISUP) consensus conference on grading of prostatic carcinoma","volume":"44","author":"van Leenders","year":"2020","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib12","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00428-016-1981-2","article-title":"Utility of Gleason pattern 4 morphologies detected on transrectal ultrasound (TRUS)-guided biopsies for prediction of upgrading or upstaging in Gleason score 3 + 4 = 7 prostate cancer","volume":"469","author":"Flood","year":"2016","journal-title":"Virchows Arch"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib13","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/his.12976","article-title":"Gleason grade 4 prostate adenocarcinoma patterns: an interobserver agreement study among genitourinary pathologists","volume":"69","author":"Kweldam","year":"2016","journal-title":"Histopathology"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib14","first-page":"3990","article-title":"Diagnosis of \"cribriform\" prostatic adenocarcinoma: an interobserver reproducibility study among urologic pathologists with recommendations","volume":"11","author":"Shah","year":"2021","journal-title":"Am J Cancer Res"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00428-020-02902-9","article-title":"Inter-observer variability of cribriform architecture and percent Gleason pattern 4 in prostate cancer: relation to clinical outcome","volume":"478","author":"van der Slot","year":"2021","journal-title":"Virchows Arch"},{"key":"10.1016\/j.path.2022.07.001_bib16","doi-asserted-by":"crossref","first-page":"151733","DOI":"10.1016\/j.anndiagpath.2021.151733","article-title":"Cribriform prostate cancer: Morphologic criteria enabling a diagnosis, based on survey of experts","volume":"52","author":"Iczkowski","year":"2021","journal-title":"Ann Diagn Pathol"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib17","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1097\/PAS.0000000000001728","article-title":"ISUP consensus definition of cribriform pattern prostate cancer","volume":"45","author":"van der Kwast","year":"2021","journal-title":"Am J Surg Pathol"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib18","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1309\/AJCPZ7WBU9YXSJPE","article-title":"Digital quantification of five high-grade prostate cancer patterns, including the cribriform pattern, and their association with adverse outcome","volume":"136","author":"Iczkowski","year":"2011","journal-title":"Am J Clin Pathol"},{"issue":"7","key":"10.1016\/j.path.2022.07.001_bib19","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1002\/1097-0142(19851001)56:7<1566::AID-CNCR2820560717>3.0.CO;2-Y","article-title":"Ductal spread in prostatic carcinoma","volume":"56","author":"Kovi","year":"1985","journal-title":"Cancer"},{"key":"10.1016\/j.path.2022.07.001_bib20","series-title":"WHO classification of tumours of the urinary system and male genital organs","author":"Moch","year":"2016"},{"issue":"10","key":"10.1016\/j.path.2022.07.001_bib21","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1097\/PAS.0000000000000465","article-title":"Prostate biopsy specimens with Gleason 3+3=6 and intraductal carcinoma: radical prostatectomy findings and clinical outcomes","volume":"39","author":"Khani","year":"2015","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1016\/j.path.2022.07.001_bib22","first-page":"2518","article-title":"Heterogeneous clinicopathological features of intraductal carcinoma of the prostate: a comparison between \"precursor-like\" and \"regular type\" lesions","volume":"7","author":"Miyai","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib23","first-page":"1328","article-title":"Intraductal carcinoma of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings","volume":"184","author":"Robinson","year":"2010","journal-title":"J\u00a0Urol"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib24","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/path.5283","article-title":"Intraductal carcinoma of the prostate in the absence of high-grade invasive carcinoma represents a molecularly distinct type of in situ carcinoma enriched with oncogenic driver mutations","volume":"249","author":"Khani","year":"2019","journal-title":"J\u00a0Pathol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib25","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/PAP.0000000000000303","article-title":"Intraductal carcinoma of the prostate: a guide for the practicing pathologist","volume":"28","author":"Varma","year":"2021","journal-title":"Adv Anat Pathol"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/his.14216","article-title":"Head to head: should the intraductal component of invasive prostate cancer be graded?","volume":"78","author":"Varma","year":"2021","journal-title":"Histopathology"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib27","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/modpathol.2015.146","article-title":"The presence of intraductal carcinoma of the prostate in needle biopsy is a significant prognostic factor for prostate cancer patients with distant metastasis at initial presentation","volume":"29","author":"Kato","year":"2016","journal-title":"Mod Pathol"},{"issue":"6","key":"10.1016\/j.path.2022.07.001_bib28","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/pros.22786","article-title":"Prognostic value of intraductal carcinoma of the prostate in radical prostatectomy specimens","volume":"74","author":"Kimura","year":"2014","journal-title":"Prostate"},{"issue":"7","key":"10.1016\/j.path.2022.07.001_bib29","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.5858\/2007-131-1103-APOTIH","article-title":"A\u00a0proposal on the identification, histologic reporting, and implications of intraductal prostatic carcinoma","volume":"131","author":"Cohen","year":"2007","journal-title":"Arch Pathol Lab Med"},{"issue":"12","key":"10.1016\/j.path.2022.07.001_bib30","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1038\/modpathol.3800702","article-title":"Intraductal carcinoma of the prostate on needle biopsy: histologic features and clinical significance","volume":"19","author":"Guo","year":"2006","journal-title":"Mod Pathol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib31","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1097\/PAS.0b013e3181cfc44b","article-title":"Atypical cribriform lesions of the prostate: relationship to prostatic carcinoma and implication for diagnosis in prostate biopsies","volume":"34","author":"Shah","year":"2010","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib32","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.pathol.2019.11.001","article-title":"Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded","volume":"52","author":"Samaratunga","year":"2020","journal-title":"Pathology"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib33","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/his.13081","article-title":"Reporting intraductal carcinoma of the prostate: a plea for greater standardization","volume":"70","author":"Varma","year":"2017","journal-title":"Histopathology"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib34","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/PAS.0000000000001104","article-title":"Comedonecrosis revisited: strong association with intraductal carcinoma of the prostate","volume":"42","author":"Fine","year":"2018","journal-title":"Am J Surg Pathol"},{"issue":"7","key":"10.1016\/j.path.2022.07.001_bib35","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/his.13833","article-title":"Prostate cancer with comedonecrosis is frequently, but not exclusively, intraductal carcinoma: a need for reappraisal of grading criteria","volume":"74","author":"Madan","year":"2019","journal-title":"Histopathology"},{"issue":"10","key":"10.1016\/j.path.2022.07.001_bib36","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.5858\/arpa.2015-0206-RA","article-title":"Intraductal carcinoma of the prostate: morphologic features, differential diagnoses, significance, and reporting practices","volume":"139","author":"Magers","year":"2015","journal-title":"Arch Pathol Lab Med"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib37","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/s41379-018-0121-8","article-title":"Integrating tertiary Gleason pattern 5 into the ISUP grading system improves prediction of biochemical recurrence in radical prostatectomy patients","volume":"32","author":"Kato","year":"2019","journal-title":"Mod Pathol"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib38","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/pros.23326","article-title":"Intraductal carcinoma of the prostate on diagnostic needle biopsy predicts prostate cancer mortality: a population-based study","volume":"77","author":"Saeter","year":"2017","journal-title":"Prostate"},{"issue":"8","key":"10.1016\/j.path.2022.07.001_bib39","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1016\/j.humpath.2014.03.011","article-title":"Clinicopathological analysis of intraductal proliferative lesions of prostate: intraductal carcinoma of prostate, high-grade prostatic intraepithelial neoplasia, and atypical cribriform lesion","volume":"45","author":"Miyai","year":"2014","journal-title":"Hum Pathol"},{"issue":"5","key":"10.1016\/j.path.2022.07.001_bib40","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/his.14179","article-title":"Intraductal carcinoma has a minimal impact on Grade Group assignment in prostate cancer biopsy and radical prostatectomy specimens","volume":"77","author":"Rijstenberg","year":"2020","journal-title":"Histopathology"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib41","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/his.14132","article-title":"Grading of prostate cancer: the impact of including intraductal carcinoma on the overall Grade Group assigned in diagnostic biopsies","volume":"77","author":"Chen-Maxwell","year":"2020","journal-title":"Histopathology"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib42","first-page":"316","article-title":"Impact of gleason subtype on prostate cancer detection using multiparametric magnetic resonance imaging: correlation with final histopathology","volume":"198","author":"Truong","year":"2017","journal-title":"J\u00a0Urol"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib43","doi-asserted-by":"crossref","first-page":"326","DOI":"10.21037\/qims.2020.01.06","article-title":"Spatial density and diversity of architectural histology in prostate cancer: influence on diffusion weighted magnetic resonance imaging","volume":"10","author":"Harmon","year":"2020","journal-title":"Quant Imaging Med Surg"},{"issue":"6","key":"10.1016\/j.path.2022.07.001_bib44","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1111\/bju.14812","article-title":"Multiparametric MRI prior to radical prostatectomy identifies intraductal and cribriform growth patterns in prostate cancer","volume":"124","author":"Tonttila","year":"2019","journal-title":"BJU Int"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib45","first-page":"104","article-title":"Role of magnetic resonance imaging targeted biopsy in detection of prostate cancer harboring adverse pathological features of intraductal carcinoma and invasive cribriform carcinoma","volume":"200","author":"Prendeville","year":"2018","journal-title":"J\u00a0Urol"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib46","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/jmri.26594","article-title":"Intraductal carcinoma of the prostate (IDC-P) lowers apparent diffusion coefficient (ADC) values among intermediate risk prostate cancers","volume":"50","author":"Currin","year":"2019","journal-title":"J\u00a0Magn Reson Imaging"},{"issue":"7","key":"10.1016\/j.path.2022.07.001_bib47","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1097\/PAI.0000000000000508","article-title":"Prostate Ductal Adenocarcinoma","volume":"26","author":"Amin","year":"2018","journal-title":"Appl Immunohistochem Mol Morphol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib48","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/PAS.0000000000000794","article-title":"Atypical intraductal cribriform proliferations of the prostate exhibit similar molecular and clinicopathologic characteristics as intraductal carcinoma of the prostate","volume":"41","author":"Hickman","year":"2017","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"10.1016\/j.path.2022.07.001_bib49","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/his.13878","article-title":"Atypical intraductal proliferation detected in prostate needle biopsy is a marker of unsampled intraductal carcinoma and other adverse pathological features: a prospective clinicopathological study of 62 cases with emphasis on pathological outcomes","volume":"75","author":"Shah","year":"2019","journal-title":"Histopathology"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib50","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/PAS.0b013e3181d6827b","article-title":"ETS gene aberrations in atypical cribriform lesions of the prostate: Implications for the distinction between intraductal carcinoma of the prostate and cribriform high-grade prostatic intraepithelial neoplasia","volume":"34","author":"Han","year":"2010","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1016\/j.path.2022.07.001_bib51","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/his.13273","article-title":"Atypical intraductal proliferation and intraductal carcinoma of the prostate on core needle biopsy: a comparative clinicopathological and molecular study with a proposal to expand the morphological spectrum of intraductal carcinoma","volume":"71","author":"Shah","year":"2017","journal-title":"Histopathology"},{"issue":"1","key":"10.1016\/j.path.2022.07.001_bib52","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12885-017-3976-z","article-title":"Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations","volume":"18","author":"Bottcher","year":"2018","journal-title":"BMC Cancer"},{"issue":"2","key":"10.1016\/j.path.2022.07.001_bib53","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1158\/1541-7786.MCR-18-0440","article-title":"Genetic and epigenetic determinants of aggressiveness in cribriform carcinoma of the prostate","volume":"17","author":"Elfandy","year":"2019","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.path.2022.07.001_bib54","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejca.2021.01.027","article-title":"Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer","volume":"147","author":"Lozano","year":"2021","journal-title":"Eur J Cancer"},{"issue":"5","key":"10.1016\/j.path.2022.07.001_bib55","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.eururo.2017.04.034","article-title":"A\u00a0prostate cancer \"nimbosus\": genomic instability and SChLAP1 dysregulation underpin aggression of intraductal and cribriform subpathologies","volume":"72","author":"Chua","year":"2017","journal-title":"Eur Urol"},{"issue":"11","key":"10.1016\/j.path.2022.07.001_bib56","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1002\/pros.23831","article-title":"PTEN loss in prostatic adenocarcinoma correlates with specific adverse histologic features (intraductal carcinoma, cribriform Gleason pattern 4 and stromogenic carcinoma)","volume":"79","author":"Shah","year":"2019","journal-title":"Prostate"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib57","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/modpathol.2012.201","article-title":"Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia","volume":"26","author":"Lotan","year":"2013","journal-title":"Mod Pathol"},{"issue":"4","key":"10.1016\/j.path.2022.07.001_bib58","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/1097-0045(20000901)44:4<265::AID-PROS1>3.0.CO;2-I","article-title":"Distinction between intraductal carcinoma of the prostate (IDC-P), high-grade dysplasia (PIN), and invasive prostatic adenocarcinoma, using molecular markers of cancer progression","volume":"44","author":"Dawkins","year":"2000","journal-title":"Prostate"},{"issue":"7","key":"10.1016\/j.path.2022.07.001_bib59","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/gcc.20560","article-title":"Chromosomal imbalances, loss of heterozygosity, and immunohistochemical expression of TP53, RB1, and PTEN in intraductal cancer, intraepithelial neoplasia, and invasive adenocarcinoma of the prostate","volume":"47","author":"Bettendorf","year":"2008","journal-title":"Genes Chromosomes Cancer"}],"container-title":["Surgical Pathology Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875918122000496?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875918122000496?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T14:42:37Z","timestamp":1761748957000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875918122000496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S1875918122000496"],"URL":"https:\/\/doi.org\/10.1016\/j.path.2022.07.001","relation":{},"ISSN":["1875-9181"],"issn-type":[{"value":"1875-9181","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cribriform Lesions of the Prostate Gland","name":"articletitle","label":"Article Title"},{"value":"Surgical Pathology Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.path.2022.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}