{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:46:15Z","timestamp":1787057175052,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","pathologyjournal.rcpa.edu.au","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pathology"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.pathol.2018.04.002","type":"journal-article","created":{"date-parts":[[2018,6,23]],"date-time":"2018-06-23T17:35:57Z","timestamp":1529775357000},"page":"554-561","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Analysis of the QuantiFERON-CMV assay, CMV viraemia and antiviral treatment following solid organ transplantation in Western Australia"],"prefix":"10.1016","volume":"50","author":[{"given":"Grace","family":"Thompson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Boan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Baumwol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aron","family":"Chakera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry","family":"MacQuillan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-9373","authenticated-orcid":false,"given":"Suda","family":"Swaminathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3002-0868","authenticated-orcid":false,"given":"Melanie","family":"Lavender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Flexman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"John","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pathol.2018.04.002_bib1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1399-3062.2006.00199.x","article-title":"Ex\u00a0vivo monitoring of human cytomegalovirus-specific CD8+ T-cell responses using QuantiFERON-CMV","volume":"9","author":"Walker","year":"2007","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.pathol.2018.04.002_bib2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/TP.0b013e31829df29d","article-title":"Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation","volume":"96","author":"Kotton","year":"2013","journal-title":"Transplantation"},{"key":"10.1016\/j.pathol.2018.04.002_bib3","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1016\/j.transproceed.2010.07.101","article-title":"Quantiferon-CMV test in prediction of cytomegalovirus infection after kidney transplantation","volume":"42","author":"Lochmanova","year":"2010","journal-title":"Transplant Proc"},{"key":"10.1016\/j.pathol.2018.04.002_bib4","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1002\/lt.24216","article-title":"Targeted individual prophylaxis offers superior risk stratification for cytomegalovirus reaction after liver transplantation","volume":"21","author":"Sood","year":"2015","journal-title":"Liver Transpl"},{"key":"10.1016\/j.pathol.2018.04.002_bib5","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/tri.12318","article-title":"Human CMV-specific T-cell responses in kidney transplantation; toward changing current risk-stratification paradigm","volume":"27","author":"Lucia","year":"2014","journal-title":"Transpl Int"},{"key":"10.1016\/j.pathol.2018.04.002_bib6","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1038\/cti.2014.3","article-title":"Clinical immune-monitoring strategies for predicting infection risk in solid organ transplantation","volume":"3","author":"Fernandez-Ruiz","year":"2014","journal-title":"Clin Transl Immunol"},{"key":"10.1016\/j.pathol.2018.04.002_bib7","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1093\/cid\/cis818","article-title":"State-of-the-art monitoring of cytomegalovirus specific cell-mediated immunity after organ transplant: a primer for the clinician","volume":"55","author":"Humar","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.pathol.2018.04.002_bib8","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1016\/j.transproceed.2016.01.046","article-title":"Clinical utility of QuantiFERON-cytomegalovirus test in management of kidney transplant recipients","volume":"48","author":"Tarasewicz","year":"2016","journal-title":"Transplant Proc"},{"key":"10.1016\/j.pathol.2018.04.002_bib9","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/ajt.12049","article-title":"Pretransplant interferon-gamma secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation","volume":"13","author":"Cantisan","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.pathol.2018.04.002_bib10","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/TP.0b013e31823c1cd4","article-title":"Clinical utility of cytomegalovirus cell medicated immunity in transplant recipients with cytomegalovirus viremia","volume":"93","author":"Lisboa","year":"2012","journal-title":"Transplantation"},{"key":"10.1016\/j.pathol.2018.04.002_bib11","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1128\/JCM.00563-13","article-title":"Comparison of cytomegalovirus (CMV) enzyme linked immunosorbent spot and CMV Quantiferon gamma interferon releasing assays in assessing risk of CMV infection in kidney transplant recipients","volume":"51","author":"Abate","year":"2013","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.pathol.2018.04.002_bib12","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1186\/s12879-017-2599-y","article-title":"Cytomegalovirus viraemia and mortality in renal transplant recipients in the era of antiviral prophylaxis. Lessons from the Western Australian experience","volume":"17","author":"Selvey","year":"2017","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.pathol.2018.04.002_bib13","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01040-17","article-title":"Monitoring of CMV-specific cell-mediated immunity in heart transplant recipients: clinical utility of the QuantiFERON-CMV assay for the management of post-transplant CMV infection","volume":"56","author":"Chiereghin","year":"2018","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.pathol.2018.04.002_bib14","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1111\/j.1600-6143.2009.02618.x","article-title":"Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients","volume":"9","author":"Kumar","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.pathol.2018.04.002_bib15","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1097\/TP.0b013e31828ee12e","article-title":"International survey of cytomegalovirus management in solid organ transplantation after the publication of consensus guidelines","volume":"95","author":"Le Page","year":"2013","journal-title":"Transplantation"},{"key":"10.1016\/j.pathol.2018.04.002_bib16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1093\/cid\/cis993","article-title":"Assessment of cytomegalovirus specific cell mediated immunity for the prediction of cytomegalovirus disease in high risk solid organ transplant recipients: a multicentre cohort study","volume":"56","author":"Manuel","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.pathol.2018.04.002_bib17","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1111\/ajt.14347","article-title":"An interventional study using cell mediated immunity to personalize therapy for cytomegalovirus infection after transplantation","volume":"17","author":"Kumar","year":"2017","journal-title":"Am J Transplant"},{"key":"10.1016\/j.pathol.2018.04.002_bib18","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1586\/1744666X.2014.943190","article-title":"Immune-based monitoring for cytomegalovirus infection in solid organ transplantation: is it ready for clinical primetime?","volume":"10","author":"Melendez","year":"2014","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1016\/j.pathol.2018.04.002_bib19","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.3390\/v6062242","article-title":"Controlling cytomegalovirus: helping the immune system take the lead","volume":"6","author":"Hanley","year":"2014","journal-title":"Viruses"},{"key":"10.1016\/j.pathol.2018.04.002_bib20","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1128\/JVI.01809-09","article-title":"Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH\/gL\/UL128-131A complex","volume":"84","author":"Macagno","year":"2010","journal-title":"Am J Virol"},{"key":"10.1016\/j.pathol.2018.04.002_bib21","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1084\/jem.20050882","article-title":"Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects","volume":"202","author":"Sylwester","year":"2005","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.pathol.2018.04.002_bib22","doi-asserted-by":"crossref","first-page":"e02009","DOI":"10.1128\/JCM.02009-17","article-title":"Immune monitoring of infectious complications in transplant patients: an important step towards improved clinical management","volume":"56","author":"Khanna","year":"2018","journal-title":"J\u00a0Clin Microbiol"}],"container-title":["Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302517307006?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031302517307006?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T00:30:24Z","timestamp":1534984224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031302517307006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S0031302517307006"],"URL":"https:\/\/doi.org\/10.1016\/j.pathol.2018.04.002","relation":{},"ISSN":["0031-3025"],"issn-type":[{"value":"0031-3025","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of the QuantiFERON-CMV assay, CMV viraemia and antiviral treatment following solid organ transplantation in Western Australia","name":"articletitle","label":"Article Title"},{"value":"Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pathol.2018.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2018 Published by Elsevier B.V. on behalf of Royal College of Pathologists of Australasia. All rights reserved.","name":"copyright","label":"Copyright"}]}}