{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:47:44Z","timestamp":1662079664621},"reference-count":19,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.patol.2017.10.004","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T07:01:19Z","timestamp":1511334079000},"page":"77-83","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patr\u00f3n MELF de infiltraci\u00f3n miometrial en el adenocarcinoma endometrioide del endometrio. Revisi\u00f3n de 70 casos"],"prefix":"10.1016","volume":"51","author":[{"given":"Francisco","family":"Tresserra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda \u00c1ngela","family":"Pascual","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireia","family":"Arenas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Blancafort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda \u00c1ngeles","family":"Mart\u00ednez-Lanao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafa","family":"F\u00e1bregas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.patol.2017.10.004_bib0100","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1097\/01.pgp.0000092161.33490.a9","article-title":"Unusual epithelial and stromal changes in myoinvasive endometrioid adenocarcinoma: A study of their frequency, associated diagnostic problems, and prognostic significance","volume":"22","author":"Murray","year":"2003","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0105","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1080\/00313020903041135","article-title":"MELF pattern invasion in endometrial carcinoma: Association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion","volume":"41","author":"Stewart","year":"2009","journal-title":"Pathology."},{"key":"10.1016\/j.patol.2017.10.004_bib0110","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/PGP.0b013e318285657b","article-title":"Lymphovascular space invasion in microcystic elongated and fragmented (MELF)-pattern well-differentiated endometrioid adenocarcinoma is associated with a higher rate of lymph node metastasis","volume":"33","author":"Hertel","year":"2014","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0115","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0140-6736(05)67063-8","article-title":"Endometrial cancer","volume":"366","author":"Amant","year":"2005","journal-title":"Lancet."},{"key":"10.1016\/j.patol.2017.10.004_bib0120","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/j.1365-2559.2011.03802.x","article-title":"MELF invasion in endometrial cancer as a risk factor for lymph node metastasis","volume":"58","author":"Pavlakis","year":"2011","journal-title":"Histopathology."},{"key":"10.1016\/j.patol.2017.10.004_bib0125","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3109\/01443615.2014.960827","article-title":"The association of the microcystic, elongated and fragmented (MELF) invasion pattern in endometrial carcinomas with deep myometrial invasion, lymphovascular space invasion and lymph node metastasis","volume":"35","author":"Dogan Altunpulluk","year":"2015","journal-title":"J Obstet Gynaecol."},{"key":"10.1016\/j.patol.2017.10.004_bib0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.humpath.2017.05.026","article-title":"Endometrioid endometrial carcinomas with MELF-type of myoinvasion: Role of immunohistochemistry in the detection of occult lymph node metastases and their clinical significance","author":"Espinosa","year":"2017","journal-title":"Hum Pathol"},{"key":"10.1016\/j.patol.2017.10.004_bib0135","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1097\/PAS.0000000000000856","article-title":"Clinicopathologic association and prognostic value of microcystic elongated, and fragmented (MELF) pattern in endometrial endometrioid carcinoma","volume":"41","author":"Kihara","year":"2017","journal-title":"Am J Surg Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0140","doi-asserted-by":"crossref","DOI":"10.1097\/PGP.0000000000000370","article-title":"MELF pattern for predicting lymph node involvement and survival in grade i-ii endometrioid-type endometrium cancer","author":"Sanci","year":"2017","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0145","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/PAS.0000000000000754","article-title":"The microcystic elongated, and fragmented (MELF) pattern of invasion: A single institution report of 464 consecutive FIGO grade 1 endometrial endometrioid adenocarcinomas","volume":"41","author":"Joehlin-Price","year":"2017","journal-title":"Am J Surg Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0150","doi-asserted-by":"crossref","DOI":"10.1097\/PGP.0000000000000362","article-title":"CXCL14-CXCR4 and CXCL12-CXCR4 axes may play important roles in the unique invasion process of endometrioid carcinoma with MELF-pattern myoinvasion","author":"Kojiro-Sanada","year":"2017","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0155","unstructured":"College of American Pathologist. Protocol for the examination of specimens from patients with carcinoma and carcinosarcoma of the Endometrium. Version 4.0.0.0 [acualizado Jun 2107; consultado Jul 2017]. Disponible en: http:\/\/www.cap.org\/ShowProperty?nodePath=\/UCMCon\/Contribution%20Folders\/WebContent\/pdf\/cp-endometrium-17protocol-4000.pdf"},{"key":"10.1016\/j.patol.2017.10.004_bib0160","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/his.12254","article-title":"Histological features associated with occult lymph node metastasis in FIGO clinical stage I, grade I endometrioid carcinoma","volume":"64","author":"Han","year":"2014","journal-title":"Histopathology."},{"key":"10.1016\/j.patol.2017.10.004_bib0165","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1097\/PGP.0000000000000137","article-title":"Unusual patterns of endometrial carcinoma including MELF and its relation to epithelial mesenchymal transition","volume":"33","author":"Zaino","year":"2014","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0170","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1136\/jcp.2009.069500","article-title":"KRAS mutation and microsatellite instability in endometrial adenocarcinomas showing MELF-type myometrial invasion","volume":"63","author":"Stewart","year":"2010","journal-title":"J Clin Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0175","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1365-2559.2009.03327.x","article-title":"Immunophenotypic features of MELF pattern invasion in endometrial adenocarcinoma: Evidence for epithelial-mesenchymal transition","volume":"55","author":"Stewart","year":"2009","journal-title":"Histopathology."},{"key":"10.1016\/j.patol.2017.10.004_bib0180","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1365-2559.2011.03893.x","article-title":"Fascin expression in low-grade uterine endometrioid adenocarcinoma: Correlation with microcystic, elongated and fragmented (MELF)-type alteration at the deep invasive margin","volume":"59","author":"Stewart","year":"2011","journal-title":"Histopathology."},{"key":"10.1016\/j.patol.2017.10.004_bib0185","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/PGP.0b013e3181e4ee4ea","article-title":"Galectin-3 expression in uterine endometrioid adenocarcinoma: Comparison of staining in conventional tumor glands and in areas of MELF pattern myometrial invasion","volume":"29","author":"Stewart","year":"2010","journal-title":"Int J Gynecol Pathol."},{"key":"10.1016\/j.patol.2017.10.004_bib0190","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1111\/cas.12999","article-title":"S100A4 accelerates the proliferation and invasion of endometrioid carcinoma and is associated with the \u201cMELF\u201d pattern","volume":"107","author":"Tahara","year":"2016","journal-title":"Cancer Sci."}],"container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885517300727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885517300727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,25]],"date-time":"2018-08-25T22:38:10Z","timestamp":1535236690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1699885517300727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S1699885517300727"],"URL":"https:\/\/doi.org\/10.1016\/j.patol.2017.10.004","relation":{},"ISSN":["1699-8855"],"issn-type":[{"value":"1699-8855","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patr\u00f3n MELF de infiltraci\u00f3n miometrial en el adenocarcinoma endometrioide del endometrio. Revisi\u00f3n de 70 casos","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Patolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.patol.2017.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Sociedad Espa\u00f1ola de Anatom\u00eda Patol\u00f3gica. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}