{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:40:05Z","timestamp":1760805605531,"version":"build-2065373602"},"reference-count":8,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100031566","name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031566","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031566","name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante","doi-asserted-by":"crossref","award":["2021-0450"],"award-info":[{"award-number":["2021-0450"]}],"id":[{"id":"10.13039\/100031566","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.patol.2025.100834","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T08:59:19Z","timestamp":1751878759000},"page":"100834","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Identification of germline mutations in DICER1 through routine somatic NGS analysis in various neoplasms"],"prefix":"10.1016","volume":"58","author":[{"given":"Leticia","family":"Gracia S\u00e1enz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Shalygina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyes","family":"Roca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samanta","family":"Ortu\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Luis","family":"Soto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Tasso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Beatriz","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artemio","family":"Pay\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Alenda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.patol.2025.100834_bib0045","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1002\/ijc.30907","article-title":"The prevalence of DICER1 pathogenic variation in population databases","volume":"141","author":"Kim","year":"2017","journal-title":"Int J Cancer"},{"key":"10.1016\/j.patol.2025.100834_bib0050","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41379-021-00905-8","article-title":"DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma","volume":"35","author":"Gonz\u00e1lez","year":"2022","journal-title":"Mod Pathol"},{"key":"10.1016\/j.patol.2025.100834_bib0055","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1016\/j.molcel.2022.10.010","article-title":"Structural and functional basis of mammalian microRNA biogenesis by Dicer","volume":"82","author":"Zapletal","year":"2022","journal-title":"Mol Cell"},{"key":"10.1016\/j.patol.2025.100834_bib0060","doi-asserted-by":"crossref","first-page":"273.e1","DOI":"10.1016\/j.anpedi.2016.05.006","article-title":"El nuevo reto en oncolog\u00eda: la secuenciaci\u00f3n NGS y su aplicaci\u00f3n a la medicina de precisi\u00f3n","volume":"85","author":"Calabria","year":"2016","journal-title":"An Pediatr (Barc)"},{"key":"10.1016\/j.patol.2025.100834_bib0065","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.annonc.2024.04.005","article-title":"Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group","volume":"35","author":"Mosele","year":"2024","journal-title":"Ann Oncol"},{"key":"10.1016\/j.patol.2025.100834_bib0070","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1055\/s-0044-1786397","article-title":"Next-generation sequencing and emerging technologies","volume":"50","author":"Kumar","year":"2024","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.patol.2025.100834_bib0075","series-title":"Ponencia presentada en XXXI Congreso nacional SEAP, Seville","article-title":"Estudio de variantes patog\u00e9nicas en l\u00ednea germinal a partir de estudio rutinario de alteraciones gen\u00e9ticas en el tumor mediante secuenciaci\u00f3n masiva. Propuesta de algoritmo de actuaci\u00f3n","author":"Alenda","year":"2023"},{"key":"10.1016\/j.patol.2025.100834_bib0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10689-012-9584-9","article-title":"10 rare tumors that warrant a genetics referral","volume":"12","author":"Banks","year":"2013","journal-title":"Fam Cancer"}],"container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885525000340?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885525000340?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:27:11Z","timestamp":1760804831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1699885525000340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1699885525000340"],"URL":"https:\/\/doi.org\/10.1016\/j.patol.2025.100834","relation":{},"ISSN":["1699-8855"],"issn-type":[{"type":"print","value":"1699-8855"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of germline mutations in DICER1 through routine somatic NGS analysis in various neoplasms","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Patolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.patol.2025.100834","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Sociedad Espa\u00f1ola de Anatom\u00eda Patol\u00f3gica. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100834"}}