{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:34:24Z","timestamp":1793385264543,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.patol.2026.100857","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:41:55Z","timestamp":1769085715000},"page":"100857","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Changes in the classification of malignant salivary gland tumours across the last three WHO editions"],"prefix":"10.1016","volume":"59","author":[{"given":"Gonzalo","family":"Rojas-Alcayaga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Pinto \u00c1vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"C\u00e1ceres Villanueva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iara","family":"Vargas Pi\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constanza","family":"Yutronic Adasme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iv\u00e1n","family":"Gallegos M\u00e9ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.patol.2026.100857_bib0210","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.5858\/arpa.2022-0461-RA","article-title":"Updated salivary gland immunohistochemistry: a review","volume":"147","author":"Swid","year":"2023","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.patol.2026.100857_bib0215","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s12105-022-01420-1","article-title":"Update from the 5th edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands","volume":"16","author":"Sk\u00e1lov\u00e1","year":"2022","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0220","first-page":"73","article-title":"La Patolog\u00eda ante un gran desaf\u00edo: el impacto de las nuevas clasificaciones de las neoplasias","volume":"56","author":"Gastearena","year":"2023","journal-title":"Rev Esp Patol"},{"key":"10.1016\/j.patol.2026.100857_bib0225","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.coms.2018.08.007","article-title":"Salivary gland malignancies","volume":"31","author":"Carlson","year":"2019","journal-title":"Oral Maxillofac Surg Clin N Am"},{"key":"10.1016\/j.patol.2026.100857_bib0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5604\/01.3001.0015.8056","article-title":"Indications for surgical treatment of major salivary glands pathologies with epidemiology analysis in adults \u2013 cohort study of 1173 cases","volume":"76","author":"Kucharska","year":"2022","journal-title":"Otolaryngol Pol Pol Otolaryngol"},{"key":"10.1016\/j.patol.2026.100857_bib0235","first-page":"9","article-title":"Frequency and histopathology by site, major pathologies symptoms and signs of salivary gland neoplasms","volume":"78","author":"Bradley","year":"2016","journal-title":"Adv Otorhinolaryngol"},{"key":"10.1016\/j.patol.2026.100857_bib0240","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s12105-020-01231-2","article-title":"Salivary gland tumors: a retrospective study of 164 cases from a single private practice service in Mexico and literature review","volume":"15","author":"Cunha","year":"2021","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0245","doi-asserted-by":"crossref","first-page":"3354","DOI":"10.1002\/cncr.32208","article-title":"Minor salivary gland tumors of the head and neck-Memorial Sloan Kettering experience: incidence and outcomes by site and histological type","volume":"125","author":"Hay","year":"2019","journal-title":"Cancer"},{"key":"10.1016\/j.patol.2026.100857_bib0250","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.bjorl.2020.06.016","article-title":"Prognostic factors and overall survival in a 15-year followup of patients with malignant salivary gland tumors: a retrospective analysis of 193 patients","volume":"88","author":"Filho","year":"2020","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.patol.2026.100857_bib0255","doi-asserted-by":"crossref","first-page":"e111","DOI":"10.4317\/medoral.26101","article-title":"Malignant salivary gland tumors: agreement between fine needle aspiration biopsy, incisional biopsy and final histopathological diagnostic","volume":"29","author":"Lacerda-Oliveira","year":"2024","journal-title":"Med Oral Patol Oral Cirugia Bucal"},{"key":"10.1016\/j.patol.2026.100857_bib0260","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1097\/PAS.0000000000001688","article-title":"Salivary mucinous adenocarcinoma is a histologically diverse single entity with recurrent AKT1 E17K mutations: clinicopathologic and molecular characterization with proposal for a unified classification","volume":"45","author":"Rooper","year":"2021","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0265","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1017\/S002221510009397X","article-title":"Intraductal carcinoma of the minor salivary gland","volume":"97","author":"Chen","year":"1983","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.patol.2026.100857_bib0270","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1097\/00000478-200608000-00013","article-title":"Low-grade intraductal carcinoma of salivary gland: report of 3 cases with marked apocrine differentiation","volume":"30","author":"Weinreb","year":"2006","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0275","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1002\/cncy.22508","article-title":"IDK what's next for IDC: the unfolding saga of intraductal carcinoma of salivary glands","volume":"129","author":"Bishop","year":"2021","journal-title":"Cancer Cytopathol"},{"key":"10.1016\/j.patol.2026.100857_bib0280","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1002\/cncy.22504","article-title":"Cytomorphologic features of intraductal salivary gland carcinoma: a multi-institutional study of 13 FNA cases with histologic, molecular, and clinical correlations","volume":"129","author":"Viswanathan","year":"2021","journal-title":"Cancer Cytopathol"},{"key":"10.1016\/j.patol.2026.100857_bib0285","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/PAS.0b013e3181d9efcc","volume":"34","author":"16Sk\u00e1lov\u00e1","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0290","doi-asserted-by":"crossref","first-page":"e143","DOI":"10.1016\/j.oooo.2020.04.007","article-title":"A systematic review of secretory carcinoma of the salivary gland: where are we?","volume":"132","author":"Alves","year":"2021","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.patol.2026.100857_bib0295","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1097\/PAS.0000000000001273","article-title":"Microsecretory adenocarcinoma: a novel salivary gland tumor characterized by a recurrent MEF2C-SS18 fusion","volume":"43","author":"Bishop","year":"2019","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0300","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1007\/s12105-021-01331-7","article-title":"Microsecretory adenocarcinoma of salivary glands: an expanded series of 24 cases","volume":"15","author":"Bishop","year":"2021","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0305","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s12105-016-0731-8","article-title":"Sclerosing microcystic adenocarcinoma of the head and neck mucosa: a neoplasm closely resembling microcystic adnexal carcinoma","volume":"10","author":"Mills","year":"2016","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0310","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.oraloncology.2019.06.002","article-title":"Polymorphous adenocarcinoma of salivary glands","volume":"95","author":"Mimica","year":"2019","journal-title":"Oral Oncol"},{"key":"10.1016\/j.patol.2026.100857_bib0315","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1002\/lary.24788","article-title":"Polymorphous low-grade adenocarcinoma: a case series and determination of recurrence","volume":"124","author":"Kimple","year":"2014","journal-title":"Laryngoscope"},{"key":"10.1016\/j.patol.2026.100857_bib0320","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1046\/j.1365-2559.2002.01439.x","article-title":"Polymorphous low-grade adenocarcinoma of the salivary glands with transformation to high-grade carcinoma","volume":"41","author":"Simpson","year":"2002","journal-title":"Histopathology"},{"key":"10.1016\/j.patol.2026.100857_bib0325","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1600-0714.2007.00522.x","article-title":"Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world","volume":"36","author":"Buchner","year":"2007","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.patol.2026.100857_bib0330","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.tripleo.2008.04.016","article-title":"Clear cell carcinoma, not otherwise specified, of salivary glands: a clinicopathologic study of 4 cases and review of the literature","volume":"106","author":"Yang","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol"},{"key":"10.1016\/j.patol.2026.100857_bib0335","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.critrevonc.2016.03.018","article-title":"Clear cell carcinoma, not otherwise specified\/hyalinising clear cell carcinoma of the salivary gland: the current nomenclature, clinical\/pathological characteristics and management","volume":"102","author":"Daniele","year":"2016","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.patol.2026.100857_bib0340","first-page":"908","article-title":"18F-FDG PET\/CT for response assessment in pediatric sebaceous carcinoma of the parotid gland","volume":"10","author":"Holzgreve","year":"2020","journal-title":"Diagn Basel Switz"},{"key":"10.1016\/j.patol.2026.100857_bib0345","first-page":"1659","article-title":"Sebaceous carcinoma arising from heterotopic salivary gland tissue in a patient with Muir\u2013Torre syndrome","volume":"47","author":"Syder","year":"2021","journal-title":"Dermatol Surg Off Publ Am Soc Dermatol Surg Al"},{"key":"10.1016\/j.patol.2026.100857_bib0350","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2147\/CMAR.S392573","article-title":"Sebaceous carcinoma of the submandibular gland a case report and review of the literature","volume":"15","author":"Ju","year":"2023","journal-title":"Cancer Manag Res"},{"key":"10.1016\/j.patol.2026.100857_bib0355","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/his.13664","article-title":"Sebaceous adenocarcinomas of the major salivary glands: a clinicopathological analysis of 10 cases","volume":"73","author":"Soares","year":"2018","journal-title":"Histopathology"},{"key":"10.1016\/j.patol.2026.100857_bib0360","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00795-021-00291-9","article-title":"A rare case of high-grade intraductal carcinoma of the upper lip: immunohistochemical and genetic analyses","volume":"54","author":"Kusafuka","year":"2021","journal-title":"Med Mol Morphol"},{"key":"10.1016\/j.patol.2026.100857_bib0365","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.wjorl.2020.01.003","article-title":"Endoscopic trans-pterygoid resection of a low-grade cribriform cystadenocarcinoma of the infratemporal fossa","volume":"6","author":"Ramjee","year":"2020","journal-title":"World J Otorhinolaryngol \u2013 Head Neck Surg"},{"key":"10.1016\/j.patol.2026.100857_bib0370","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s12105-020-01128-0","article-title":"Low-grade apocrine intraductal carcinoma: expanding the morphologic and molecular spectrum of an enigmatic salivary gland tumor","volume":"14","author":"Bishop","year":"2020","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0375","doi-asserted-by":"crossref","first-page":"5751","DOI":"10.12998\/wjcc.v8.i22.5751","article-title":"Sebaceous lymphadenocarcinoma of the parotid gland: a case report","volume":"8","author":"Hao","year":"2020","journal-title":"World J Clin Cases"},{"key":"10.1016\/j.patol.2026.100857_bib0380","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.618201","article-title":"Case report: complete response of recurrent and metastatic cystadenocarcinoma of the parotid gland with a single course of combined nivolumab and ipilimumab therapy","volume":"11","author":"Nakamura","year":"2021","journal-title":"Front Oncol"},{"key":"10.1016\/j.patol.2026.100857_bib0385","doi-asserted-by":"crossref","DOI":"10.1016\/j.oraloncology.2021.105314","article-title":"Salivary gland cystadenocarcinoma: rare neoplasm in buccal mucosa","volume":"118","author":"de Lima-Souza","year":"2021","journal-title":"Oral Oncol"},{"key":"10.1016\/j.patol.2026.100857_bib0390","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/his.13990","article-title":"Histopathological evaluation of minor salivary gland papillary-cystic tumours: focus on genetic alterations in sialadenoma papilliferum and intraductal papillary mucinous neoplasm","volume":"76","author":"Nakaguro","year":"2020","journal-title":"Histopathology"},{"key":"10.1016\/j.patol.2026.100857_bib0395","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.3390\/cancers15041236","article-title":"Histopathological aspects of the prognostic factors for salivary gland cancers","volume":"15","author":"Nishida","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.patol.2026.100857_bib0400","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1007\/s12105-018-0920-8","article-title":"Metastasising pleomorphic salivary adenoma: a rare case report of a massive untreated minor salivary gland pleomorphic adenoma with concurrent ipsilateral cervical node metastases","volume":"13","author":"Watson","year":"2018","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.patol.2026.100857_bib0405","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.ijom.2020.01.002","article-title":"Maxillofacial diagnostic features of the enigmatic metastasizing pleomorphic adenoma","volume":"49","author":"Shoukair","year":"2020","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.patol.2026.100857_bib0410","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2739\/kurumemedj.MS6912009","article-title":"Small cell neuroendocrine carcinoma of the parotid gland: an uncommon example of incompletely encapsulated tumor including s100 protein-positive clear cells","volume":"69","author":"Harada","year":"2023","journal-title":"Kurume Med J"}],"container-title":["Revista Espa\u00f1ola de Patolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885526000024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699885526000024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T12:33:39Z","timestamp":1771245219000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1699885526000024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1699885526000024"],"URL":"https:\/\/doi.org\/10.1016\/j.patol.2026.100857","relation":{},"ISSN":["1699-8855"],"issn-type":[{"value":"1699-8855","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Changes in the classification of malignant salivary gland tumours across the last three WHO editions","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Patolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.patol.2026.100857","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Sociedad Espa\u00f1ola de Anatom\u00eda Patol\u00f3gica. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100857"}}