{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:48:58Z","timestamp":1782949738157,"version":"3.54.5"},"reference-count":67,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008414","name":"University of Canterbury","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008414","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Biochemistry and Behavior"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.pbb.2012.05.010","type":"journal-article","created":{"date-parts":[[2012,5,24]],"date-time":"2012-05-24T13:30:07Z","timestamp":1337866207000},"page":"381-389","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Subsequent anxiety-related behavior in rats exposed to low-dose methadone during gestation, lactation or both periods consecutively"],"prefix":"10.1016","volume":"102","author":[{"given":"Felicity M.","family":"Daly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N.","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianne J.","family":"Woodward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pbb.2012.05.010_bb0005","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0163-1047(79)90492-8","article-title":"Effects of alcohol withdrawal and undernutrition on cannibalism of rat pups","volume":"25","author":"Abel","year":"1979","journal-title":"Behav Neural Biol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0015","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0003-3472(73)80065-X","article-title":"Tests for emotionality in rats and mice: A review","volume":"21","author":"Archer","year":"1973","journal-title":"Anim Behav"},{"key":"10.1016\/j.pbb.2012.05.010_bb0020","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0091-6773(75)90636-7","article-title":"Rodent sex differences in emotional and related behavior","volume":"14","author":"Archer","year":"1975","journal-title":"Behav Biol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0010","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.0001-6349.2005.00510.x","article-title":"Methadone maintenance program in pregnancy in a Swiss perinatal centre (II): neonatal outcome and social resources","volume":"84","author":"Arlettaz","year":"2005","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.pbb.2012.05.010_bb0025","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/fn.87.2.F106","article-title":"Central and autonomic signs with in utero drug exposure","volume":"87","author":"Bada","year":"2002","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.pbb.2012.05.010_bb0030","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00005237-200203000-00008","article-title":"Treatment of neonatal abstinence syndrome with breast milk containing methadone","volume":"15","author":"Ballard","year":"2002","journal-title":"J Perinat Neonatal Nurs"},{"key":"10.1016\/j.pbb.2012.05.010_bb0035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/10550881003684871","article-title":"Prenatal drug exposure: infant and toddler outcomes","volume":"29","author":"Bandstra","year":"2010","journal-title":"J Addict Dis"},{"key":"10.1016\/j.pbb.2012.05.010_bb0040","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0091-3057(97)00596-0","article-title":"Neonatal withdrawal following pre- and postnatal exposure to methadone in the rat","volume":"60","author":"Barr","year":"1998","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.pbb.2012.05.010_bb0045","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1651-2227.1994.tb13386.x","article-title":"Substance use in pregnancy: do we care?","volume":"404","author":"Boer","year":"1994","journal-title":"Acta Paediatr Suppl"},{"key":"10.1016\/j.pbb.2012.05.010_bb0350","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0300-483X(86)90009-0","article-title":"A comparative study of the reproductive effects of methadone and benzo(a)pyrene in the pregnant and pseudopregnant rat","volume":"42","author":"Bui","year":"1986","journal-title":"Toxicology"},{"key":"10.1016\/j.pbb.2012.05.010_bb0050","doi-asserted-by":"crossref","first-page":"5335","DOI":"10.1073\/pnas.95.9.5335","article-title":"Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat","volume":"95","author":"Caldji","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.pbb.2012.05.010_bb0055","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1037\/h0047206","article-title":"Development of fear in the rat as measured by behavior in the open field","volume":"55","author":"Candland","year":"1962","journal-title":"J Comp Physiol Psychol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0060","first-page":"220","article-title":"Perinatal addiction: the effects of maternal narcotic and nonnarcotic substance abuse on the fetus and neonate","volume":"49","author":"Chasnoff","year":"1984","journal-title":"NIDA Res Monogr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0065","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF00426755","article-title":"Aversiveness of oral methadone in rats","volume":"57","author":"Chipkin","year":"1978","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pbb.2012.05.010_bb0070","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1037\/h0079429","article-title":"Children of methadone-dependent women: developmental outcomes","volume":"63","author":"de Cubas","year":"1993","journal-title":"Am J Orthopsychiatry"},{"key":"10.1016\/j.pbb.2012.05.010_bb0075","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1136\/adc.48.10.757","article-title":"Quantitative growth and development of human brain","volume":"48","author":"Dobbing","year":"1973","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.pbb.2012.05.010_bb0080","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-3782(79)90022-7","article-title":"Comparative aspects of the brain growth spurt","volume":"3","author":"Dobbing","year":"1979","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.pbb.2012.05.010_bb0085","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1001\/archinte.1966.00290160004002","article-title":"Narcotic blockade","volume":"188","author":"Dole","year":"1966","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pbb.2012.05.010_bb0090","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0959-4388(99)80016-6","article-title":"Maternal care and the development of stress responses","volume":"9","author":"Francis","year":"1999","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0095","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3109\/00207458009147593","article-title":"Methadone exposure in utero: effects on open-field activity in weanling rats","volume":"11","author":"Freeman","year":"1980","journal-title":"Int J Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0100","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3758\/CABN.1.4.371","article-title":"Testosterone increases analgesia, anxiolysis, and cognitive performance of male rats","volume":"1","author":"Frye","year":"2001","journal-title":"Cogn Affect Behav Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0105","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1093\/jn\/111.3.480","article-title":"Composition of rat milk from day 5 to 20 of lactation and milk intake of lean and preobese zucker pups","volume":"111","author":"Godbole","year":"1981","journal-title":"J Nutr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0110","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0001-6918(71)90029-1","article-title":"Sex differences in emotional behaviour in mammals including man","volume":"35","author":"Gray","year":"1971","journal-title":"Acta Psychol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0115","first-page":"87","article-title":"Behavioral effects of fetal and neonatal exposure to methadone in the rat","volume":"1","author":"Grove","year":"1979","journal-title":"Neurobehav Toxicol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0120","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1126\/science.1198116","article-title":"Weaning and growth of artificially reared rats","volume":"190","author":"Hall","year":"1975","journal-title":"Science"},{"key":"10.1016\/j.pbb.2012.05.010_bb0125","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ntt.2004.09.004","article-title":"HPA axis dysregulation following prenatal opiate exposure and postnatal withdrawal","volume":"27","author":"Hamilton","year":"2005","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0130","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1749-6632.1989.tb21018.x","article-title":"Developmental consequences of prenatal exposure to methadone","volume":"562","author":"Hans","year":"1989","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0135","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1177\/026988119701100408","article-title":"Chronic mild stress-induced reductions in saccharin intake depend upon feeding status","volume":"11","author":"Hatcher","year":"1997","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0140","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0306-4603(94)00044-Y","article-title":"Vagal tone regulation during sustained attention in boys exposed to opiates in utero","volume":"20","author":"Hickey","year":"1995","journal-title":"Addict Behav"},{"key":"10.1016\/j.pbb.2012.05.010_bb0145","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/14640746808400147","article-title":"Effects of age on novelty reactions and exploration in rats","volume":"20","author":"Hughes","year":"1968","journal-title":"Q J Exp Psychol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0150","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/FBP.0b013e3282eff0e8","article-title":"Sex does matter: comments on the prevalence of male-only investigations of drug effects on rodent behaviour","volume":"18","author":"Hughes","year":"2007","journal-title":"Behav Pharmacol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0155","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3758\/BF03333109","article-title":"Effects of prenatal exposure to chronic caffeine on locomotor and emotional behavior","volume":"15","author":"Hughes","year":"1987","journal-title":"Psychobiology"},{"key":"10.1016\/j.pbb.2012.05.010_bb0160","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0892-0362(91)90048-2","article-title":"Behavioral effects of exposure to caffeine during gestation, lactation or both","volume":"13","author":"Hughes","year":"1991","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0165","first-page":"429","article-title":"Methadone and heroin during pregnancy: a review of behavioral effects in human and animal offspring","volume":"4","author":"Hutchings","year":"1982","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0170","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0892-0362(90)90090-Y","article-title":"Issues of risk assessment: lessons from the use and abuse of drugs during pregnancy","volume":"12","author":"Hutchings","year":"1990","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0095-5108(18)30531-1","article-title":"Animal models of opiate, cocaine, and cannabis use","volume":"18","author":"Hutchings","year":"1991","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0180","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0892-0362(92)90030-E","article-title":"Prenatal administration of methadone using the osmotic minipump: effects on maternal and offspring toxicity, growth, and behavior in the rat","volume":"14","author":"Hutchings","year":"1992","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0185","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0892-0362(93)90011-C","article-title":"Prenatal administration of methadone in the rat increases acoustic startle amplitude at age 3 weeks","volume":"15","author":"Hutchings","year":"1993","journal-title":"Neurotoxicol Teratol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0195","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1177\/0890334403261027","article-title":"Methadone maintenance and lactation: a review of the literature and current management guidelines","volume":"20","author":"Jansson","year":"2004","journal-title":"J Hum Lact"},{"key":"10.1016\/j.pbb.2012.05.010_bb0190","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1542\/peds.2007-1182","article-title":"Methadone maintenance and breastfeeding in the neonatal period","volume":"121","author":"Jansson","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.pbb.2012.05.010_bb0200","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1037\/0735-7044.108.1.107","article-title":"Effects of chronic and acute cocaine treatment on the onset of maternal behavior and aggression in Sprague\u2013Dawley rats","volume":"108","author":"Johns","year":"1994","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0205","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0163-6383(84)80027-2","article-title":"24-month neurobehavioral follow-up of children of methadone-maintained mothers","volume":"7","author":"Johnson","year":"1984","journal-title":"Infant Behav Dev"},{"key":"10.1016\/j.pbb.2012.05.010_bb0345","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0166-4328(88)90121-0","article-title":"Impaired spatial navigation in adult female but not adult male rats exposed to alcohol during the brain growth spurt","volume":"27","author":"Kelly","year":"1988","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pbb.2012.05.010_bb0225","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/S0022-3565(25)13081-4","article-title":"Perinatal methadone exposure produces physical dependence and altered behavioral development in the rat","volume":"277","author":"Kunko","year":"1996","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.pbb.2012.05.010_bb0230","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1479-828X.1995.tb01863.x","article-title":"Maternal methadone dosage and neonatal withdrawal","volume":"35","author":"Malpas","year":"1995","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0235","first-page":"A38","article-title":"Breastfeeding reduces the severity of neonatal abstinence syndrome [abstract]","volume":"33","author":"Malpas","year":"1997","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.pbb.2012.05.010_bb0240","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/026119290403201s25","article-title":"Non-invasively assessing disturbance and stress in laboratory rats by scoring chromodacryorrhoea","volume":"32","author":"Mason","year":"2004","journal-title":"Altern Lab Anim"},{"key":"10.1016\/j.pbb.2012.05.010_bb0245","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0014-2999(01)01512-6","article-title":"Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine (\u201cEcstasy\u201d)","volume":"433","author":"Morley","year":"2001","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0250","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0166-4328(96)00176-3","article-title":"Perinatal cannibinoid exposure modifies the sociosexual approach behavior and the mesolimbic dopaminergic activity of adult male rats","volume":"75","author":"Navarro","year":"1996","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.pbb.2012.05.010_bb0255","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/0269881106065188","article-title":"Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar long-lasting deficits in object recognition and reduced social interaction in rats","volume":"20","author":"O'Shea","year":"2006","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0260","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0091-3057(92)90451-K","article-title":"Morphine and methadone dependence in the rat: withdrawal and brain met-enkephalin levels","volume":"42","author":"Pierce","year":"1992","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.pbb.2012.05.010_bb0265","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/dev.20085","article-title":"Repeated MDMA (\u201cEcstasy\u201d) exposure in adolescent male rats alters temperature regulation, spontaneous motor activity, attention, and serotonin transporter binding","volume":"47","author":"Piper","year":"2005","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0270","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0014-2999(03)01272-X","article-title":"The open field as a paradigm to measure effects of drugs on anxiety-like behaviors: a review","volume":"463","author":"Prut","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.pbb.2012.05.010_bb0275","first-page":"1161","article-title":"Comparison of the effects of infant handling, isolation, and nonhandling on acoustic startle, prepulse inhibition, locomotion, and HPA activity in the adult rat","volume":"24","author":"Pryce","year":"2001","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0280","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1651-2227.2008.01011.x","article-title":"Acoustic cry characteristics of infants exposed to methadone during pregnancy","volume":"98","author":"Quick","year":"2009","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0285","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ijdevneu.2007.07.001","article-title":"Sexual dimorphism in rats: effects of early maternal separation and variable chronic stress on pituitary-adrenal axis and behavior","volume":"25","author":"Renard","year":"2007","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0290","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0022-3476(82)80115-7","article-title":"Children of methadone-maintained mothers: follow-up to 18 months of age","volume":"101","author":"Rosen","year":"1982","journal-title":"J Pediatr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0295","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1749-6632.1988.tb37236.x","article-title":"Drug-addicted mothers, their infants, and SIDS","volume":"533","author":"Rosen","year":"1988","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0300","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0149-7634(79)90012-5","article-title":"Stress, behavioral arousal, and open field activity: a reexamination of emotionality in the rat","volume":"3","author":"Roth","year":"1979","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.pbb.2012.05.010_bb0305","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s12098-008-0107-5","article-title":"Neonatal abstinence syndrome","volume":"75","author":"Serane","year":"2008","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0310","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1523\/JNEUROSCI.17-07-02626.1997","article-title":"Prenatal stress induces high anxiety and postnatal handling induces low anxiety in adult offspring: correlation with stress-induced corticosterone secretion","volume":"17","author":"Vall\u00e9e","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.pbb.2012.05.010_bb0315","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1037\/0033-2909.83.3.482","article-title":"The open-field test: a critical review","volume":"83","author":"Walsh","year":"1976","journal-title":"Psychol Bull"},{"key":"10.1016\/j.pbb.2012.05.010_bb0320","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/jn\/123.suppl_2.382","article-title":"Use of pup in a cup model to study brain development","volume":"123","author":"West","year":"1993","journal-title":"J Nutr"},{"key":"10.1016\/j.pbb.2012.05.010_bb0325","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/00004583-199506000-00019","article-title":"Pilot study of behavioral and emotional disturbances in the high-risk children of parents with opioid dependence","volume":"34","author":"Wilens","year":"1995","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.pbb.2012.05.010_bb0330","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.brainresbull.2005.09.014","article-title":"A comparative study of morphine treatment regimen prior to mating and during late pregnancy","volume":"68","author":"Yim","year":"2006","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.pbb.2012.05.010_bb0335","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1159\/000240975","article-title":"Effect of chronic maternal methadone exposure on perinatal development","volume":"31","author":"Zagon","year":"1977","journal-title":"Biol Neonate"},{"key":"10.1016\/j.pbb.2012.05.010_bb0340","first-page":"121","article-title":"Motor activity and learning ability in rats perinatally exposed to methadone","volume":"27","author":"Zagon","year":"1979","journal-title":"NIDA Res Monogr"}],"container-title":["Pharmacology Biochemistry and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091305712001451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091305712001451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:31:52Z","timestamp":1758774712000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091305712001451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0091305712001451"],"URL":"https:\/\/doi.org\/10.1016\/j.pbb.2012.05.010","relation":{},"ISSN":["0091-3057"],"issn-type":[{"value":"0091-3057","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Subsequent anxiety-related behavior in rats exposed to low-dose methadone during gestation, lactation or both periods consecutively","name":"articletitle","label":"Article Title"},{"value":"Pharmacology Biochemistry and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pbb.2012.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}