{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:25:15Z","timestamp":1790187915340,"version":"4.1.0"},"reference-count":216,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T00:00:00Z","timestamp":1682208000000},"content-version":"am","delay-in-days":357,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Biochemistry and Behavior"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.pbb.2022.173390","type":"journal-article","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T11:04:50Z","timestamp":1650279890000},"page":"173390","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Prenatal and adolescent alcohol exposure programs immunity across the lifespan: CNS-mediated regulation"],"prefix":"10.1016","volume":"216","author":[{"given":"Terrence","family":"Deak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn T.","family":"Kelliher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah J.","family":"Wojcik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anny","family":"Gano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pbb.2022.173390_bb0005","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0741-8329(00)00076-8","article-title":"Alcohol modulates cytokine secretion and synthesis in human fetus: an in vivo and in vitro study","volume":"21","author":"Ahluwalia","year":"2000","journal-title":"Alcohol"},{"key":"10.1016\/j.pbb.2022.173390_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.02247","article-title":"Immunosenescence and its hallmarks: how to oppose aging strategically? A review of potential options for therapeutic intervention","volume":"10","author":"Aiello","year":"2019","journal-title":"Front. Immunol."},{"issue":"24","key":"10.1016\/j.pbb.2022.173390_bb1300","doi-asserted-by":"crossref","first-page":"8285","DOI":"10.1523\/JNEUROSCI.0976-10.2010","article-title":"Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damage","volume":"30","author":"Alfonso-Loeches","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.pbb.2022.173390_bb0015","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2013"},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0020","doi-asserted-by":"crossref","DOI":"10.1111\/hepr.13473","article-title":"Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: current concepts and perspectives","volume":"50","author":"Arab","year":"2020","journal-title":"Hepatol. Res."},{"issue":"9","key":"10.1016\/j.pbb.2022.173390_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2011.03.007","article-title":"From models to mechanisms: odorant communication as a key determinant of social behavior in rodents during illness-associated states","volume":"35","author":"Arakawa","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.pbb.2022.173390_bb0030","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/S0002-9343(01)00834-8","article-title":"Antipyretics: mechanisms of action and clinical use in fever suppression","volume":"111","author":"Aronoff","year":"2001","journal-title":"Am. J. Med."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0035","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/00024382-200116050-00003","article-title":"Gender differences in cytokine secretion by human peripheral blood mononuclear cells- role of estrogen in modulating LPS-induced cytokine secretion in an ex vivo septic model","volume":"16","author":"Asai","year":"2001","journal-title":"Shock"},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/S0091-3057(99)00165-3","article-title":"The immunobiology of sexual behavior gender differences in the suppression of sexual activity during illness","volume":"64","author":"Avitsur","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.pbb.2022.173390_bb0045","series-title":"The Alcohol Use Disorders Identification Test Guidelines for Use in Primary Care","author":"Babor","year":"2001"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0050","doi-asserted-by":"crossref","DOI":"10.1093\/alcalc\/agw026","article-title":"Evaluation of TLR4 inhibitor, T5342126, in modulation of ethanol-drinking behavior in alcohol-dependent mice","volume":"51","author":"Bajo","year":"2016","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.pbb.2022.173390_bb0055","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bbi.2021.08.207","article-title":"Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats","volume":"98","author":"Bake","year":"2021","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0060","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1080\/23328940.2020.1735927","article-title":"Temperature regulation in women- effects of the menstrual cycle","volume":"7","author":"Baker","year":"2020","journal-title":"Temperature"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0096864","article-title":"Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals","volume":"9","author":"Bala","year":"2014","journal-title":"PLoS ONE"},{"issue":"8","key":"10.1016\/j.pbb.2022.173390_bb0070","article-title":"Alcohol consumption and lung cancer: a review of the epidemiologic evidence","volume":"10","author":"Bandera","year":"2001","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"issue":"8","key":"10.1016\/j.pbb.2022.173390_bb0075","doi-asserted-by":"crossref","DOI":"10.2174\/1381612053381684","article-title":"Blood-brain barrier transport of cytokines: a mechanism for neuropathology","volume":"11","author":"Banks","year":"2005","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.pbb.2022.173390_bb0080","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.pnpbp.2015.09.001","article-title":"Opposing effects of alcohol on the immune system","volume":"65","author":"Barr","year":"2016","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.pbb.2022.173390_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2019.03.010","article-title":"Neuroimmunology of the female brain across the lifespan: plasticity to psychopathology","author":"Barrientos","year":"2019","journal-title":"Brain Behav. Immun."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0090","doi-asserted-by":"crossref","DOI":"10.1089\/aid.2009.0211","article-title":"Alcohol use accelerates HIV disease progression","volume":"26","author":"Baum","year":"2010","journal-title":"AIDS Res. Hum. Retrovir."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0095","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.cell.2014.03.011","article-title":"Role of the microbiota in immunity and inflammation","volume":"157","author":"Belkaid","year":"2014","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2011.02.305","article-title":"Alcohol abuse and Streptococcus pneumoniae infections: consideration of virulence factors and impaired immune responses","volume":"45","author":"Bhatty","year":"2011","journal-title":"Alcohol"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0105","doi-asserted-by":"crossref","DOI":"10.7326\/0003-4819-103-1-42","article-title":"Bone disease in alcohol abuse","volume":"103","author":"Bikle","year":"1985","journal-title":"Ann. Intern. Med."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0110","doi-asserted-by":"crossref","DOI":"10.1165\/ajrcmb.17.1.f132","article-title":"The role of nuclear factor-kappa B in cytokine gene regulation","volume":"17","author":"Blackwell","year":"1997","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"10","key":"10.1016\/j.pbb.2022.173390_bb1200","doi-asserted-by":"crossref","first-page":"6893","DOI":"10.4049\/jimmunol.175.10.6893","article-title":"Involvement of TLR4\/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes","volume":"175","author":"Blanco","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2017.06.013","article-title":"Mutation of the inhibitory ethanol site in GABAA \u03c11 receptors promotes tolerance to ethanol-induced motor incoordination","volume":"123","author":"Blednov","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pbb.2022.173390_bb0120","first-page":"30","article-title":"Jejunal microflora in patients with chronic alcohol abuse","volume":"31","author":"Bode","year":"1984","journal-title":"Hepato-Gastroenterology"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/S0168-8278(87)80003-X","article-title":"Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess","volume":"4","author":"Bode","year":"1987","journal-title":"J. Hepatol."},{"issue":"39","key":"10.1016\/j.pbb.2022.173390_bb0130","article-title":"Immune network dysregulation associated with child neurodevelopmental delay: modulatory role of prenatal alcohol exposure","volume":"17","author":"Bodnar","year":"2020","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.pbb.2022.173390_bb0135","doi-asserted-by":"crossref","DOI":"10.1111\/acer.14784","article-title":"Evidence for long-lasting alterations in the fecal microbiota following prenatal alcohol exposure","author":"Bodnar","year":"2022","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2016.03.033","article-title":"Neonatal binge alcohol exposure increases microglial activation in the developing rat hippocampus","volume":"324","author":"Boschen","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.pbb.2022.173390_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2016.05.035","article-title":"Immunoadolescence: neuroimmune development and adolescent behavior","volume":"70","author":"Brenhouse","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"10","key":"10.1016\/j.pbb.2022.173390_bb0150","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12414","article-title":"Female sex hormones influence the febrile response induced by lipopolysaccharide, cytokines and prostaglandins but not by interleukin-1\u03b2 in rats","volume":"28","author":"Brito","year":"2016","journal-title":"J. Neuroendocrinol."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0155","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/nri.2017.1","article-title":"Immune regulation by glucocorticoids","volume":"17","author":"Cain","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2020.108219","article-title":"Cross-country and historical variation in alcohol consumption among older men and women: leveraging recently harmonized survey data in 21 countries","volume":"215","author":"Calvo","year":"2020","journal-title":"Drug Alcohol Depend."},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0165","doi-asserted-by":"crossref","DOI":"10.1097\/01.alc.0000192039.21305.55","article-title":"Alcohol-induced bone loss and deficient bone repair","volume":"29","author":"Chakkalakal","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2015.09.020","article-title":"Prenatal exposure to ethanol stimulates hypothalamic CCR2 chemokine receptor system: possible relation to increased density of orexigenic peptide neurons and ethanol drinking in adolescent offspring","volume":"310","author":"Chang","year":"2015","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0175","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10286-017-0420-z","article-title":"Autonomic control of body temperature and blood pressure: influences of female sex hormones","volume":"27","author":"Charkoudian","year":"2017","journal-title":"Clin. Auton. Res."},{"issue":"9","key":"10.1016\/j.pbb.2022.173390_bb0180","doi-asserted-by":"crossref","DOI":"10.1038\/s41386-019-0326-7","article-title":"Early life alcohol exposure primes hypothalamic microglia to later-life hypersensitivity to immune stress: possible epigenetic mechanism","volume":"44","author":"Chastain","year":"2019","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0190","article-title":"The fetal alcohol syndrome and fetal alcohol effects on immune competence","volume":"30","author":"Chiappelli","year":"1995","journal-title":"Alcohol Alcohol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0195","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10753-020-01335-5","article-title":"Fever induced by Zymosan A and polyinosinic-polycytidylic acid in female rats: influence of sex hormones and the participation of endothelin-1","volume":"44","author":"Coelho","year":"2021","journal-title":"Inflammation"},{"issue":"9","key":"10.1016\/j.pbb.2022.173390_bb0200","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-015-3906-1","article-title":"Mechanisms of neuroimmune gene induction in alcoholism","volume":"233","author":"Crews","year":"2016","journal-title":"Psychopharmacology"},{"issue":"7","key":"10.1016\/j.pbb.2022.173390_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2012.09.030","article-title":"High mobility group box 1\/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence","volume":"73","author":"Crews","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0210","article-title":"Neuroimmune function and the consequences of alcohol exposure","volume":"37","author":"Crews","year":"2015","journal-title":"Alcohol Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2017.01.031","article-title":"The role of neuroimmune signaling in alcoholism","volume":"122","author":"Crews","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.pbb.2022.173390_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2019.110632","article-title":"Immunosenescence: a systems-level overview of immune cell biology and strategies for improving vaccine responses","volume":"124","author":"Crooke","year":"2019","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.pbb.2022.173390_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2020.107904","article-title":"Intermittent binge-like ethanol exposure during adolescence attenuates the febrile response by reducing brown adipose tissue thermogenesis in rats","volume":"209","author":"Cruz","year":"2020","journal-title":"Drug Alcohol Depend."},{"issue":"1\u20133","key":"10.1016\/j.pbb.2022.173390_bb0230","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.ejphar.2004.07.040","article-title":"Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity","volume":"500","author":"Dantzer","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.pbb.2022.173390_bb0235","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1152\/physrev.00039.2016","article-title":"Neuroimmune interactions: from the BRAIN to the immune system and vice versa","volume":"98","author":"Dantzer","year":"2018","journal-title":"Physiol. Rev."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0240","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1176\/appi.ajp.157.5.745","article-title":"Age at first alcohol use: a risk factor for the development of alcohol disorders","volume":"157","author":"DeWit","year":"2000","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0245","doi-asserted-by":"crossref","DOI":"10.1111\/acer.13527","article-title":"Beneficial effect of alcohol withdrawal on gut permeability and microbial translocation in patients with alcohol use disorder","volume":"42","author":"Donnadieu-Rigole","year":"2018","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0250","first-page":"167","article-title":"Adolescent neuroimmune function and its interaction with alcohol","volume":"161","author":"Doremus-Fitzwater","year":"2022","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.pbb.2022.173390_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2015.02.032","article-title":"Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure","volume":"148","author":"Doremus-Fitzwater","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.pbb.2022.173390_bb0260","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2020.00082","article-title":"Lingering effects of prenatal alcohol exposure on basal and ethanol-evoked expression of inflammatory-related genes in the CNS of adolescent and adult rats","volume":"14","author":"Doremus-Fitzwater","year":"2020","journal-title":"Front. Behav. Neurosci."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0265","article-title":"Ethanol inhibition of signal transduction in superoxide production by rat alveolar macrophages. A proposed mechanism for ethanol related pneumonia","volume":"18","author":"Dorio","year":"1988","journal-title":"Ann. Clin. Lab. Sci."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0270","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0892-0362(90)90094-S","article-title":"Prenatal alcohol exposure: comparability of effects in humans and animal models","volume":"12","author":"Driscoll","year":"1990","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.pbb.2022.173390_bb0275","doi-asserted-by":"crossref","DOI":"10.1001\/archsurg.134.12.1342","article-title":"Gender-based differences in outcome in patients with sepsis","volume":"134","author":"Eachempati","year":"1999","journal-title":"Arch. Surg."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0280","doi-asserted-by":"crossref","DOI":"10.1093\/ajcp\/74.5.725","article-title":"Pathology of alcoholism","volume":"74","author":"Edmondson","year":"1980","journal-title":"Am. J. Clin. Pathol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0290","doi-asserted-by":"crossref","DOI":"10.1146\/annurev-immunol-032712-100003","article-title":"Immunology of the maternal-fetal Interface","volume":"31","author":"Erlebacher","year":"2013","journal-title":"Annu. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0295","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1189\/jlb.1209775","article-title":"Endogenous ligands of TLR2 and TLR4: agonists or assistants?","volume":"87","author":"Erridge","year":"2010","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.pbb.2022.173390_bb0310","series-title":"Nature Reviews Immunology","first-page":"335","article-title":"Fever and the thermal regulation of immunity: the immune system feels the heat","volume":"15(6)","author":"Evans","year":"2015"},{"issue":"7","key":"10.1016\/j.pbb.2022.173390_bb1400","doi-asserted-by":"crossref","first-page":"4733","DOI":"10.4049\/jimmunol.0803590","article-title":"Critical role of TLR4 response in the activation of microglia induced by ethanol","volume":"183","author":"Fernandez-Lizarbe","year":"2009","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb1500","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/jnc.12276","article-title":"Ethanol induces TLR4\/TLR2 association, triggering an inflammatory response in microglial cells","volume":"126","author":"Fernandez-Lizarbe","year":"2013","journal-title":"J. Neurochem."},{"key":"10.1016\/j.pbb.2022.173390_bb0315","first-page":"1457","article-title":"Fever and behavioral thermoregulation in young and old rats","volume":"280","author":"Florez-Duquet","year":"2001","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.pbb.2022.173390_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurobiolaging.2017.01.025","article-title":"A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged fischer 344 rats","volume":"54","author":"Gano","year":"2017","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.pbb.2022.173390_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2019.577083","article-title":"Rapid alterations in neuroimmune gene expression after acute ethanol: timecourse, sex differences and sensitivity to cranial surgery","volume":"337","author":"Gano","year":"2019","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2020.155126","article-title":"Gene expression profiling reveals a lingering effect of prenatal alcohol exposure on inflammatory-related genes during adolescence and adulthood","volume":"133","author":"Gano","year":"2020","journal-title":"Cytokine"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0335","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2011.09.002","article-title":"Alcoholic liver disease: pathogenesis and new therapeutic targets","volume":"141","author":"Gao","year":"2011","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0340","first-page":"279","article-title":"Prenatal alcohol exposure and the developing immune system","volume":"37","author":"Gauthier","year":"2015","journal-title":"Alcohol Res."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0345","doi-asserted-by":"crossref","DOI":"10.1097\/00000658-199910000-00003","article-title":"Alcohol interventions in a trauma center as a means of reducing the risk of injury recurrence","volume":"230","author":"Gentilello","year":"1999","journal-title":"Ann. Surg."},{"key":"10.1016\/j.pbb.2022.173390_bb0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2015.06.035","article-title":"Age and sex differences in c-fos expression and serum corticosterone concentration following LPS treatment","volume":"305","author":"Girard-Joyal","year":"2015","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0355","doi-asserted-by":"crossref","DOI":"10.1038\/nri1571","article-title":"Stress-induced immune dysfunction: implications for health","volume":"5","author":"Glaser","year":"2005","journal-title":"Nat. Rev. Immunol."},{"issue":"7","key":"10.1016\/j.pbb.2022.173390_bb0360","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.19-07-02799.1999","article-title":"Interleukin-1\u03b2 in immune cells of the abdominal vagus nerve: a link between the immune and nervous systems?","volume":"19","author":"Goehler","year":"1999","journal-title":"J. Neurosci."},{"issue":"1\u20133","key":"10.1016\/j.pbb.2022.173390_bb0365","article-title":"Vagal immune-to-brain communication: a visceral chemosensory pathway","volume":"85","author":"Goehler","year":"2000","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.pbb.2022.173390_bb0370","article-title":"Alcohol consumption and binge drinking during pregnancy among adults aged 18\u201349 years \u2014 United States, 2018\u20132020","volume":"7110\u201313","author":"Gosdin","year":"2022","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0375","doi-asserted-by":"crossref","DOI":"10.1038\/nm.3189","article-title":"Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection","volume":"19","author":"Grainger","year":"2013","journal-title":"Nat. Med."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.cld.2012.08.011","article-title":"Liver cancer and alcohol","volume":"16","author":"Grewal","year":"2012","journal-title":"Clin. Liver Dis."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0385","doi-asserted-by":"crossref","DOI":"10.1080\/13543784.2017.1260544","article-title":"Investigational drugs targeting the prostaglandin E2 signaling pathway for the treatment of inflammatory pain","volume":"26","author":"Gr\u00f6sch","year":"2017","journal-title":"Expert Opin. Investig. Drugs"},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0390","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/alcalc\/agn105","article-title":"Foetal alcohol spectrum disorders and alterations in brain and behaviour","volume":"44","author":"Guerri","year":"2009","journal-title":"Alcohol Alcohol."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0395","doi-asserted-by":"crossref","DOI":"10.1007\/s11904-010-0060-6","article-title":"Alcohol and HIV disease progression: weighing the evidence","volume":"7","author":"Hahn","year":"2010","journal-title":"Curr. HIV\/AIDS Rep."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0400","first-page":"929","article-title":"The contribution of the vagus nerve in interleukin-1beta-induced fever is dependent on dose","volume":"280","author":"Hansen","year":"2001","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"key":"10.1016\/j.pbb.2022.173390_bb0405","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01078","article-title":"Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment","volume":"10","author":"Harjunp\u00e4\u00e4","year":"2019","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0410","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.2002-16.2016","article-title":"Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents","volume":"37","author":"Harris","year":"2017","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0420","doi-asserted-by":"crossref","DOI":"10.1159\/000201507","article-title":"Mucosal bacterial growth in the upper gastrointestinal tract in alcoholics (heavy drinkers)","volume":"58","author":"Hauge","year":"1997","journal-title":"Digestion"},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0425","doi-asserted-by":"crossref","DOI":"10.1002\/dev.1031","article-title":"Stress-induced sickness behaviors: an alternative hypothesis for responses during maternal separation","volume":"39","author":"Hennessy","year":"2001","journal-title":"Dev. Psychobiol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb1600","doi-asserted-by":"crossref","first-page":"18024","DOI":"10.1038\/s41598-018-36626-3","article-title":"Toll-like receptor-4 disruption suppresses adipose tissue remodeling and increases survival in cancer cachexia syndrome","volume":"8","author":"Henriques","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pbb.2022.173390_bb0430","series-title":"The Routledge Handbook of Social Work and Addictive Behaviors","first-page":"191","article-title":"The lay of the land: fetal alcohol spectrum disorder (FASD) as a whole-body diagnosis","author":"Himmelreich","year":"2020"},{"issue":"51","key":"10.1016\/j.pbb.2022.173390_bb0435","doi-asserted-by":"crossref","DOI":"10.1038\/sj.onc.1209933","article-title":"Transcriptional regulation via the NF-\u03baB signaling module","volume":"25","author":"Hoffmann","year":"2006","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0440","doi-asserted-by":"crossref","DOI":"10.1111\/acer.12005","article-title":"Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells","volume":"37","author":"Hou","year":"2013","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0445","doi-asserted-by":"crossref","DOI":"10.7189\/jogh.11.05013","article-title":"Risk of infection and transmission of SARS-CoV-2 among children and adolescents in households, communities and educational settings: a systematic review and meta-analysis","volume":"11","author":"Irfan","year":"2021","journal-title":"J. Glob. Health"},{"key":"10.1016\/j.pbb.2022.173390_bb0450","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.2741\/1383","article-title":"Prostaglandin E2 as a mediator of fever- synthesis and catabolism","volume":"9","author":"Ivanov","year":"2004","journal-title":"Front. Biosci."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0455","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.cyto.2013.10.004","article-title":"Changes in central and peripheral inflammatory responses to lipopolysaccharide in ovariectomized female rats","volume":"65","author":"Iwasa","year":"2014","journal-title":"Cytokine"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0460","doi-asserted-by":"crossref","DOI":"10.1038\/nri3665","article-title":"Innate immunity to influenza virus infection","volume":"14","author":"Iwasaki","year":"2014","journal-title":"Nat. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb1405","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1006\/clin.1997.4412","article-title":"Epidemiology and estimated population burden of selected autoimmune diseases in the United States","volume":"84","author":"Jacobson","year":"1997","journal-title":"Clin. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0465","doi-asserted-by":"crossref","DOI":"10.4103\/0975-7406.76489","article-title":"Acute-phase proteins: as diagnostic tool","volume":"3","author":"Jain","year":"2011","journal-title":"J. Pharm. Bioallied Sci."},{"key":"10.1016\/j.pbb.2022.173390_bb0470","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1203\/00006450-198106000-00005","article-title":"Immune deficiency in fetal alcohol syndrome","volume":"15","author":"Johnson","year":"1981","journal-title":"Pediatr. Res."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0475","doi-asserted-by":"crossref","DOI":"10.1378\/chest.107.1.214","article-title":"Rapidly fatal outcome of bacteremic Klebsiella pneumoniae pneumonia in alcoholics","volume":"107","author":"Jong","year":"1995","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0480","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2014.09.033","article-title":"The effect of acute alcohol intoxication on gut wall integrity in healthy male volunteers; a randomized controlled trial","volume":"49","author":"de Jong","year":"2015","journal-title":"Alcohol"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0485","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.2010.01356.x","article-title":"Alcohol exposure and mechanisms of tissue injury and repair","volume":"35","author":"Jung","year":"2011","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0490","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2016.01.017","article-title":"Risk of mortality and physiologic injury evident with lower alcohol exposure among HIV infected compared with uninfected men","volume":"161","author":"Justice","year":"2016","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.pbb.2022.173390_bb0495","article-title":"Neuroinflammatory contribution of microglia and astrocytes in fetal alcohol spectrum disorders","author":"Kane","year":"2020","journal-title":"J. Neurosci. Res."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0500","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037767","article-title":"Expression of toll-like receptors in the developing brain","volume":"7","author":"Kaul","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.pbb.2022.173390_bb0505","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2014.00461","article-title":"Toll-like receptor signaling pathways","volume":"5","author":"Kawasaki","year":"2014","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0510","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhep.2008.10.028","article-title":"Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats","volume":"50","author":"Keshavarzian","year":"2009","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0515","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1530-0277.1999.tb04023.x","article-title":"Effects of prenatal exposure to alcohol on the release of adenocorticotropic hormone, corticosterone, and proinflammatory cytokines","volume":"23","author":"Kim","year":"1999","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"10","key":"10.1016\/j.pbb.2022.173390_bb0520","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/nri.2016.90","article-title":"Sex differences in immune responses","volume":"16","author":"Klein","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0530","first-page":"274","article-title":"Alcohol metabolism\u2019s damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochrome P450 2E1","volume":"29","author":"Koop","year":"2006","journal-title":"Alcohol Res. Health"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0535","doi-asserted-by":"crossref","DOI":"10.1093\/aje\/155.6.496","article-title":"Dose-specific meta-analysis and sensitivity analysis of the relation between alcohol consumption and lung cancer risk","volume":"155","author":"Korte","year":"2002","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.pbb.2022.173390_bb0540","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01830","article-title":"Aspects of gut microbiota and immune system interactions in infectious diseases, immunopathology, and cancer","volume":"9","author":"Lazar","year":"2018","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0545","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1080\/03602532.2019.1679169","article-title":"Ethanol and its metabolites: update on toxicity, benefits, and focus on immunomodulatory effects","volume":"51","author":"Le Dar\u00e9","year":"2019","journal-title":"Drug Metab. Rev."},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2012.04.001","article-title":"Role of intestinal permeability and inflammation in the biological and behavioral control of alcohol-dependent subjects","volume":"26","author":"Leclercq","year":"2012","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pbb.2022.173390_bb0555","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2020.172906","article-title":"Effect of alcohol use on the adolescent brain and behavior","volume":"192","author":"Lees","year":"2020","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.pbb.2022.173390_bb0560","doi-asserted-by":"crossref","DOI":"10.1100\/2012\/740308","article-title":"Chronic-alcohol-abuse-induced oxidative stress in the development of acute respiratory distress syndrome","volume":"2012","author":"Liang","year":"2012","journal-title":"Sci. World J."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0565","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-04669-7","article-title":"Quantity of alcohol drinking positively correlates with serum levels of endotoxin and markers of monocyte activation","volume":"7","author":"Liangpunsakul","year":"2017","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.pbb.2022.173390_bb0570","doi-asserted-by":"crossref","DOI":"10.1111\/apa.13148","article-title":"Alcohol during pregnancy worsens acute respiratory infections in children","volume":"104","author":"Libster","year":"2015","journal-title":"Acta Paediatr."},{"issue":"11","key":"10.1016\/j.pbb.2022.173390_bb0575","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1019020108","article-title":"Binge alcohol drinking is associated with GABAA 2-regulated toll-like receptor 4 (TLR4) expression in the central amygdala","volume":"108","author":"Liu","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.pbb.2022.173390_bb0580","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/2525967","article-title":"Oxidative stress in neurodegenerative diseases: from molecular mechanisms to clinical applications","volume":"2017","author":"Liu","year":"2017","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"10","key":"10.1016\/j.pbb.2022.173390_bb0585","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/j.psyneuen.2012.02.018","article-title":"Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats","volume":"37","author":"Loram","year":"2012","journal-title":"Psychoneuroendocrinology"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0595","doi-asserted-by":"crossref","DOI":"10.1097\/MOG.0b013e3282f0d012","article-title":"The functional interactions of commensal bacteria with intestinal secretory IgA","volume":"23","author":"Macpherson","year":"2007","journal-title":"Curr. Opin. Gastroenterol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0600","doi-asserted-by":"crossref","DOI":"10.1037\/0033-295X.105.1.83","article-title":"Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition","volume":"105","author":"Maier","year":"1998","journal-title":"Psychol. Rev."},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0605","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.4049\/jimmunol.0803206","article-title":"The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes","volume":"183","author":"Mandrekar","year":"2009","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0610","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jri.2006.01.004","article-title":"Sexual dimorphism in expression of receptors for bacterial lipopolysaccharides in murine macrophages: a possible mechanism for gender-based differences in endotoxic shock susceptibility","volume":"71","author":"Marriott","year":"2006","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0615","article-title":"Neuroendocrine and neuroimmune responses in male and female rats: evidence for functional immaturity of the neuroimmune system during early adolescence","author":"Marsland","year":"2021","journal-title":"Eur. J. Neurosci."},{"issue":"Suppl","key":"10.1016\/j.pbb.2022.173390_bb0620","first-page":"1","article-title":"Management of alcoholic hepatitis","volume":"56","author":"Mathurin","year":"2012","journal-title":"J. Hepatol."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0625","doi-asserted-by":"crossref","DOI":"10.1002\/ddrr.68","article-title":"Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies","volume":"15","author":"May","year":"2009","journal-title":"Dev. Disabil. Res. Rev."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0630","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2017.21896","article-title":"Prevalence of fetal alcohol Spectrum disorders in 4 US communities","volume":"319","author":"May","year":"2018","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0635","doi-asserted-by":"crossref","DOI":"10.1111\/adb.12539","article-title":"Chronic ethanol consumption: role of TLR3\/TRIF-dependent signaling","volume":"23","author":"McCarthy","year":"2018","journal-title":"Addict. Biol."},{"key":"10.1016\/j.pbb.2022.173390_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2012.08.063","article-title":"From the stressed adolescent to the anxious and depressed adult: investigations in rodent models","volume":"249","author":"McCormick","year":"2013","journal-title":"Neuroscience"},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0645","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.0803881","article-title":"Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections","volume":"182","author":"McGill","year":"2009","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0650","doi-asserted-by":"crossref","DOI":"10.1097\/MAJ.0b013e31823ede77","article-title":"Alcohol abuse, the alveolar macrophage and pneumonia","volume":"343","author":"Mehta","year":"2012","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.pbb.2022.173390_bb0655","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.681810","article-title":"Effects of lipopolysaccharide-binding protein (LBP) single nucleotide polymorphism (SNP) in infections, inflammatory diseases, metabolic disorders and cancers","volume":"12","author":"Meng","year":"2021","journal-title":"Front. Immunol."},{"issue":"9","key":"10.1016\/j.pbb.2022.173390_bb0660","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1111\/j.1530-0277.2006.00177.x","article-title":"The alcoholism generator","volume":"30","author":"Miller","year":"2006","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0665","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0006-8993(97)00705-1","article-title":"Subdiaphragmatic vagotomy does not prevent fever following intracerebroventricular prostaglandin E2: further evidence for the importance of vagal afferents in immune- to-brain communication","volume":"766","author":"Milligan","year":"1997","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0670","doi-asserted-by":"crossref","DOI":"10.1093\/alcalc\/agy016","article-title":"Impact of alcohol on HIV disease pathogenesis, comorbidities and aging: integrating preclinical and clinical findings","volume":"53","author":"Molina","year":"2018","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.pbb.2022.173390_bb0675","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/6978936","article-title":"The role of toll-like receptor 4 in infectious and noninfectious inflammation","volume":"2016","author":"Molteni","year":"2016","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0680","doi-asserted-by":"crossref","DOI":"10.1080\/00952990.2016.1211667","article-title":"Immune activation and neuroinflammation in alcohol use and HIV infection: evidence for shared mechanisms","volume":"43","author":"Monnig","year":"2016","journal-title":"Am. J. Drug Alcohol Abuse"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0685","doi-asserted-by":"crossref","DOI":"10.1111\/j.1600-0897.2010.00836.x","article-title":"The immune system in pregnancy: a unique complexity","volume":"63","author":"Mor","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0690","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2014.02.007","article-title":"Central neural regulation of Brown adipose tissue thermogenesis and energy expenditure","volume":"19","author":"Morrison","year":"2014","journal-title":"Cell Metab."},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0695","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/j.1530-0277.2011.01441.x","article-title":"Alcohol, smoking, and drug use among inuit women of childbearing age during pregnancy and the risk to children","volume":"35","author":"Muckle","year":"2011","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0700","doi-asserted-by":"crossref","DOI":"10.1038\/labinvest.3780446","article-title":"Leukocyte-endothelial cell interactions in the inflammatory response","volume":"82","author":"Muller","year":"2002","journal-title":"Lab. Investig."},{"issue":"2 Pt 2","key":"10.1016\/j.pbb.2022.173390_bb0705","first-page":"R284","article-title":"Sex-related differences in fever development of rats","volume":"252","author":"Murakami","year":"1987","journal-title":"Am. J. Physiol."},{"issue":"7","key":"10.1016\/j.pbb.2022.173390_bb0710","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.1600924","article-title":"Human binge alcohol intake inhibits TLR4\u2013MyD88 and TLR4\u2013TRIF responses but not the TLR3\u2013TRIF pathway: HspA1A and PP1 play selective regulatory roles","volume":"200","author":"Muralidharan","year":"2018","journal-title":"J. Immunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0715","unstructured":"National Institute on Alcohol Abuse and Alcoholism, n.d., National Institute on Alcohol Abuse and Alcoholism (n.d.). Fetal alcohol exposure. https:\/\/www.niaaa.nih.gov\/publications\/brochures-and-fact-sheets\/fetal-alcohol-exposure."},{"key":"10.1016\/j.pbb.2022.173390_bb0720","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01107","article-title":"Lifelong impacts of moderate prenatal alcohol exposure on neuroimmune function","volume":"9","author":"Noor","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.pbb.2022.173390_bb0725","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.bbi.2016.12.016","article-title":"Prenatal alcohol exposure potentiates chronic neuropathic pain, spinal glial and immune cell activation and alters sciatic nerve and DRG cytokine levels","volume":"61","author":"Noor","year":"2017","journal-title":"Brain Behav. Immun."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0730","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0096053","article-title":"Synthesis of IL-6 by hepatocytes is a normal response to common hepatic stimuli","volume":"9","author":"Norris","year":"2014","journal-title":"PloS One"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0735","doi-asserted-by":"crossref","DOI":"10.1111\/adb.12543","article-title":"Young alcohol binge drinkers have elevated blood endotoxin, peripheral inflammation and low cortisol levels: neuropsychological correlations in women","volume":"23","author":"Orio","year":"2018","journal-title":"Addict. Biol."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb1800","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/acer.14777","article-title":"A review of alcohol-pathogen interactions: New insights into combined disease pathomechanisms","volume":"46","author":"Osna","year":"2022","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0740","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-017-0918-2","article-title":"TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders","volume":"14","author":"Pascual","year":"2017","journal-title":"J. Neuroinflammation"},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0745","doi-asserted-by":"crossref","DOI":"10.1038\/nrendo.2012.189","article-title":"The vagus nerve and the inflammatory reflex\u2013linking immunity and metabolism","volume":"8","author":"Pavlov","year":"2012","journal-title":"Nat. Rev. Endocrinol."},{"issue":"3\u20134","key":"10.1016\/j.pbb.2022.173390_bb0750","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.physbeh.2009.02.040","article-title":"Prostaglandins and sickness behavior: old story, new insights","volume":"97","author":"Pecchi","year":"2009","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.pbb.2022.173390_bb0755","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/bs.irn.2019.08.001","article-title":"From adolescence to late aging: a comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan","volume":"148","author":"Perkins","year":"2019","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.pbb.2022.173390_bb0760","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.bbi.2020.11.013","article-title":"Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: sex differences and role of purigenic receptors","volume":"91","author":"Perkins","year":"2021","journal-title":"Brain Behav. Immun."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0765","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.3136-11.2012","article-title":"Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence","volume":"32","author":"Ponomarev","year":"2012","journal-title":"J. Neurosci."},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0770","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19123856","article-title":"Innate immunity cells and the neurovascular unit","volume":"19","author":"Presta","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0780","doi-asserted-by":"crossref","DOI":"10.1111\/acer.13919","article-title":"The toll-like receptor 3 agonist Poly(I:C) induces rapid and lasting changes in gene expression related to glutamatergic function and increases ethanol self-Administration in Rats","volume":"43","author":"Randall","year":"2019","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0785","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-9-450","article-title":"The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review","volume":"9","author":"Rehm","year":"2009","journal-title":"BMC Public Health"},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb0790","doi-asserted-by":"crossref","DOI":"10.15288\/jsad.2019.80.515","article-title":"Adverse health outcomes associated with fetal alcohol exposure: a systematic review focused on cardio-renal outcomes","volume":"80","author":"Reid","year":"2019","journal-title":"J. Stud. Alcohol Drugs"},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0795","doi-asserted-by":"crossref","DOI":"10.3390\/nu13061810","article-title":"The breast milk immunoglobulinome","volume":"13","author":"Rio-Aige","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.pbb.2022.173390_bb0800","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/B978-0-12-801284-0.00002-6","article-title":"Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans","volume":"118","author":"Robinson","year":"2014","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.pbb.2022.173390_bb0805","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1566-0702(00)00232-0","article-title":"Lipopolysaccharide transport from the peritoneal cavity to the blood: is it controlled by the vagus nerve?","volume":"85","author":"Romanovsky","year":"2000","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.pbb.2022.173390_bb0810","doi-asserted-by":"crossref","DOI":"10.2741\/1690","article-title":"Fever and hypothermia in systemic inflammation: recent discoveries and revisions","volume":"10","author":"Romanovsky","year":"2005","journal-title":"Front. Biosci."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0815","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1002\/j.2040-4603.2014.tb00582.x","article-title":"Mechanisms of fever production and lysis: lessons from experimental LPS fever","volume":"4","author":"Roth","year":"2014","journal-title":"Compr. Physiol."},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0820","doi-asserted-by":"crossref","DOI":"10.1111\/acer.14209","article-title":"Time course of blood and brain Cytokine\/Chemokine levels following adolescent alcohol exposure and withdrawal in rats","volume":"43","author":"Sanchez-Alavez","year":"2019","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0825","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2018.07.005","article-title":"Time course of microglia activation and brain and blood cytokine\/chemokine levels following chronic ethanol exposure and protracted withdrawal in rats","volume":"76","author":"Sanchez-Alavez","year":"2019","journal-title":"Alcohol"},{"issue":"8","key":"10.1016\/j.pbb.2022.173390_bb0830","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/nn.3159","article-title":"Neural circuitry engaged by prostaglandins during the sickness syndrome","volume":"15","author":"Saper","year":"2012","journal-title":"Nat. Neurosci."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0835","doi-asserted-by":"crossref","DOI":"10.1016\/S0031-3025(16)39817-8","article-title":"The synthesis and secretion of plasma proteins in the liver","volume":"10","author":"Schreiber","year":"1978","journal-title":"Pathology"},{"issue":"22","key":"10.1016\/j.pbb.2022.173390_bb0840","doi-asserted-by":"crossref","first-page":"5918","DOI":"10.1182\/blood-2011-03-340281","article-title":"Sex differences in resident immune cell phenotype underlie more efficient acute inflammatory responses in female mice","volume":"118","author":"Scotland","year":"2011","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0845","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2009.11.032","article-title":"Dual roles for perivascular macrophages in immune-to-brain signaling","volume":"65","author":"Serrats","year":"2010","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0850","article-title":"White matter microstructure in fetal alcohol spectrum disorders: a systematic review of diffusion tensor imaging studies","volume":"40","author":"Sherbaf","year":"2019","journal-title":"Hum. Brain Mapp."},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0855","article-title":"Alcohol\u2019s effects on lung health and immunity","volume":"37","author":"Simet","year":"2015","journal-title":"Alcohol Res."},{"issue":"1821","key":"10.1016\/j.pbb.2022.173390_bb0860","article-title":"Evolution of the immune system in humans from infancy to old age","volume":"282","author":"Simon","year":"2015","journal-title":"Proc. R. Soc. B Biol. Sci."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0865","doi-asserted-by":"crossref","DOI":"10.1016\/S0149-7634(00)00014-2","article-title":"The adolescent brain and age-related behavioral manifestations","volume":"24","author":"Spear","year":"2000","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.pbb.2022.173390_bb0870","series-title":"Young People and Alcohol: Impact, Policy, Prevention, Treatment","first-page":"66","article-title":"Alcohol and the developing brain","author":"Spear","year":"2011"},{"issue":"2 SUPPL.2","key":"10.1016\/j.pbb.2022.173390_bb0875","article-title":"Adolescent neurodevelopment","volume":"52","author":"Spear","year":"2013","journal-title":"J. Adolesc. Health"},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0880","doi-asserted-by":"crossref","DOI":"10.1038\/nrn.2018.10","article-title":"Effects of adolescent alcohol consumption on the brain and behaviour","volume":"19","author":"Spear","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.pbb.2022.173390_bb0885","doi-asserted-by":"crossref","DOI":"10.1097\/01.ALC.0000171046.78556.66","article-title":"Fetal or infantile exposure to ethanol promotes ethanol ingestion in adolescence and adulthood: a theoretical review","volume":"29","author":"Spear","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb0890","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2016.11.014","article-title":"A users guide to HPA axis research","volume":"178","author":"Spencer","year":"2017","journal-title":"Physiol. Behav."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0895","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00213-011-2500-4","article-title":"Binge drinking differentially affects adolescent male and female brain morphometry","volume":"220","author":"Squeglia","year":"2011","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.pbb.2022.173390_bb0905","series-title":"Key Substance Use and Mental Health Indicators in the United States: Results From the 2020 National Survey on Drug Use and Health (PEP21-07-01-003)","author":"Substance Abuse and Mental Health Services Administration","year":"2021"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0910","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-44302-3","article-title":"Dose-dependent effects of chronic alcohol drinking on peripheral immune responses","volume":"9","author":"Sureshchandra","year":"2019","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.pbb.2022.173390_bb0915","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3748\/wjg.v16.i11.1321","article-title":"Alcoholic liver disease and the gut-liver axis","volume":"16","author":"Szabo","year":"2010","journal-title":"World J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb0920","first-page":"159","article-title":"Alcohol\u2019s effect on host defense","volume":"37","author":"Szabo","year":"2012","journal-title":"Alcohol Res."},{"issue":"44","key":"10.1016\/j.pbb.2022.173390_bb0925","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.1427-04.2004","article-title":"Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites","volume":"24","author":"Takei","year":"2004","journal-title":"J. Neurosci. Off. J. Soc. Neurosci."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0930","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1530-0277.2000.tb04629.x","article-title":"Effect of acute ethanol administration on the intestinal absorption of endotoxin in rats","volume":"24","author":"Tamai","year":"2000","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0935","doi-asserted-by":"crossref","DOI":"10.1016\/S0165-5728(99)00102-2","article-title":"Fetal alcohol exposure attenuates interleukin-1\u03b2-induced fever: neuroimmune mechanisms","volume":"99","author":"Taylor","year":"1999","journal-title":"J. Neuroimmunol."},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb0940","doi-asserted-by":"crossref","DOI":"10.1089\/089771502762300256","article-title":"Alcohol consumption in traumatic brain injury: attenuation of TBI-induced hyperthermia and neurocognitive deficits","volume":"19","author":"Taylor","year":"2002","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0945","first-page":"44","article-title":"Alcohol consumption attenuates febrile responses to lipopolysaccharide and Interleukin-1 in male rats","volume":"26","author":"Taylor","year":"2002","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb0950","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/acer.13333","article-title":"Effects of binge-like ethanol exposure during adolescence on the febrile response in rats","volume":"41","author":"Telles","year":"2017","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb0955","doi-asserted-by":"crossref","DOI":"10.1007\/s11481-016-9691-8","article-title":"Effects of moderate prenatal alcohol exposure during early gestation in rats on inflammation across the maternal-fetal-immune Interface and later-life immune function in the offspring","volume":"11","author":"Terasaki","year":"2016","journal-title":"J. NeuroImmune Pharmacol."},{"issue":"9","key":"10.1016\/j.pbb.2022.173390_bb0960","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph6092426","article-title":"Alcohol consumption and development of acute respiratory distress syndrome: a population-based study","volume":"6","author":"Thakur","year":"2009","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.pbb.2022.173390_bb0965","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1046\/j.1365-2168.1999.01181.x","article-title":"Preoperative alcoholism and postoperative morbidity","volume":"86","author":"Tonnesen","year":"1999","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.pbb.2022.173390_bb0970","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/0140-6736(92)91405-W","article-title":"Postoperative morbidity among symptom-free alcohol misusers","volume":"340","author":"Tonnesen","year":"1992","journal-title":"Lancet"},{"issue":"7194","key":"10.1016\/j.pbb.2022.173390_bb0975","article-title":"Effect of preoperative abstinence on poor postoperative outcome in alcohol misusers: randomised controlled trial","volume":"318","author":"Tonnesen","year":"1999","journal-title":"BMJ (Clinical Research Ed.)"},{"issue":"1","key":"10.1016\/j.pbb.2022.173390_bb0980","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.1999.79.1.1","article-title":"Regulation of the hypothalamic-pituitary-adrenal Axis by cytokines: actions and mechanisms of action","volume":"79","author":"Turnbulll","year":"1999","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.pbb.2022.173390_bb0985","series-title":"Dietary Guidelines for Americans, 2020-2025. DietaryGuidelines.gov","author":"U.S. Department of Agriculture","year":"2020"},{"issue":"5483","key":"10.1016\/j.pbb.2022.173390_bb0990","doi-asserted-by":"crossref","DOI":"10.1038\/252473a0","article-title":"Fever in the lizard Dipsosaurus dorsalis","volume":"252","author":"Vaughn","year":"1974","journal-title":"Nature"},{"key":"10.1016\/j.pbb.2022.173390_bb0995","article-title":"Alcohol, inflammation, and blood-brain barrier function in health and disease across development","author":"Vore","year":"2022","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.pbb.2022.173390_bb1000","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2017.00078","article-title":"Adolescent ethanol exposure leads to stimulus-specific changes in cytokine reactivity and hypothalamic-pituitary-adrenal axis sensitivity in adulthood","volume":"11","author":"Vore","year":"2017","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.pbb.2022.173390_bb1005","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108635","article-title":"Adolescent intermittent ethanol (AIE) produces sex specific alterations in adult neuroimmune gene expression and ethanol sensitivity that are independent of ethanol metabolism","volume":"195","author":"Vore","year":"2021","journal-title":"Neuropharmacology"},{"issue":"12","key":"10.1016\/j.pbb.2022.173390_bb1010","doi-asserted-by":"crossref","DOI":"10.1111\/acer.13511","article-title":"Alcohol and stress activation of microglia and neurons: brain regional effects","volume":"41","author":"Walter","year":"2017","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb1015","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bbi.2018.12.006","article-title":"Toll-like receptor 3 dynamics in female C57BL\/6J mice: regulation of alcohol intake","volume":"77","author":"Warden","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pbb.2022.173390_bb1020","article-title":"Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL\/6J male mice","volume":"77","author":"Warden","year":"2019","journal-title":"Brain Behav. Immun."},{"issue":"11","key":"10.1016\/j.pbb.2022.173390_bb1100","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/j.1432-2277.2009.00927.x","article-title":"The aging of the immune system","volume":"22","author":"Weiskopf","year":"2009","journal-title":"Transpl. Int."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb1025","article-title":"Endotoxin and kupffer cell activation in alcoholic liver disease","volume":"27","author":"Wheeler","year":"2003","journal-title":"Alcohol Res. Health"},{"key":"10.1016\/j.pbb.2022.173390_bb1030","doi-asserted-by":"crossref","DOI":"10.1007\/s001340050041","article-title":"Incidence and mortality of severe sepsis in surgical intensive care patients: the influence of patient gender on disease process and outcome","volume":"26","author":"Wichmann","year":"2000","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.pbb.2022.173390_bb1040","first-page":"5","article-title":"Advances in the science and treatment of alcohol use disorder","author":"Witkiewitz","year":"2019","journal-title":"Sci. Adv."},{"issue":"5","key":"10.1016\/j.pbb.2022.173390_bb1045","doi-asserted-by":"crossref","DOI":"10.1111\/j.1476-5381.2011.01572.x","article-title":"Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice","volume":"165","author":"Wu","year":"2012","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.pbb.2022.173390_bb1050","article-title":"Neural architecture in lymphoid organs: hard-wired antigen presenting cells and neurite networks in antigen entrance areas","volume":"6","author":"W\u00fclfing","year":"2018","journal-title":"Immun. Inflammation Dis."},{"issue":"10","key":"10.1016\/j.pbb.2022.173390_bb1055","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.3390\/cells10102791","article-title":"Neurons are a primary driver of inflammation via release of HMGB1","volume":"10","author":"Yang","year":"2021","journal-title":"Cells"},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb1700","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.pharmthera.2014.07.002","article-title":"Role of microglia in ethanol-induced neurodegenerative disease: Pathological and behavioral dysfunction at different developmental stages","volume":"144","author":"Yang","year":"2014","journal-title":"Pharmacol. Ther."},{"issue":"4","key":"10.1016\/j.pbb.2022.173390_bb1060","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.1993.tb00862.x","article-title":"Fetal alcohol exposure attenuates lipopolysaccharide-induced fever in rats","volume":"17","author":"Yirmiya","year":"1993","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.pbb.2022.173390_bb1065","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1006\/brbi.1996.0019","article-title":"Effects of fetal alcohol exposure on fever, sickness behavior, and pituitary-adrenal activation induced by interleukin-1b in young adult rats","volume":"10","author":"Yirmiya","year":"1996","journal-title":"Brain Behav. Immun."},{"issue":"6070","key":"10.1016\/j.pbb.2022.173390_bb1070","doi-asserted-by":"crossref","DOI":"10.1126\/science.1215584","article-title":"Structural basis of TLR5-flagellin recognition and signaling","volume":"335","author":"Yoon","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.pbb.2022.173390_bb1075","first-page":"463","article-title":"Innate immunity of the gut: mucosal defense in health and disease","volume":"38","author":"Yuan","year":"2004","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"issue":"3","key":"10.1016\/j.pbb.2022.173390_bb1080","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2011.11.005","article-title":"Prenatal alcohol exposure alters the course and severity of adjuvant-induced arthritis in female rats","volume":"26","author":"Zhang","year":"2012","journal-title":"Brain Behav. Immun."},{"issue":"4\u20136","key":"10.1016\/j.pbb.2022.173390_bb1085","article-title":"CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death","volume":"26","author":"Zou","year":"2006","journal-title":"Cell. Mol. Neurobiol."}],"container-title":["Pharmacology Biochemistry and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091305722000697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0091305722000697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T04:42:39Z","timestamp":1758775359000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0091305722000697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":216,"alternative-id":["S0091305722000697"],"URL":"https:\/\/doi.org\/10.1016\/j.pbb.2022.173390","relation":{},"ISSN":["0091-3057"],"issn-type":[{"value":"0091-3057","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal and adolescent alcohol exposure programs immunity across the lifespan: CNS-mediated regulation","name":"articletitle","label":"Article Title"},{"value":"Pharmacology Biochemistry and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pbb.2022.173390","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"173390"}}