{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T01:01:44Z","timestamp":1773363704113,"version":"3.50.1"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Biochemistry and Behavior"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.pbb.2024.173882","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T08:17:29Z","timestamp":1730449049000},"page":"173882","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Molecular signature underlying (R)-ketamine rapid antidepressant response on anhedonic-like behavior induced by sustained exposure to stress"],"prefix":"10.1016","volume":"245","author":[{"given":"Ellen","family":"Scotton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola Rampelotto","family":"Ziani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Luiza Boff","family":"Wilges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Henrique","family":"da Rosa Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Azambuja","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9ferson Ferraz","family":"Goularte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tain\u00e1","family":"Schons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Borges","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirson Jo\u00e3o","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josimar Macedo","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Ant\u00f4nio","family":"de Bastiani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Giovanni","family":"de Oliveira Soares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas Bernardo","family":"Paix\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caren Daniele Galeano","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Henrique","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriane R.","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pbb.2024.173882_bb0005","first-page":"11","article-title":"Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues clinical","volume":"16","author":"Duman","year":"2014","journal-title":"Neurosciences"},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0015","doi-asserted-by":"crossref","first-page":"896","DOI":"10.4103\/1673-5374.184455","article-title":"Neuroprotective role of galectin-1 in central nervous system pathophysiology","volume":"11","author":"Aalinkeel","year":"2016","journal-title":"Neural Regen. Res."},{"issue":"7","key":"10.1016\/j.pbb.2024.173882_bb0020","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.3390\/ph16071013","article-title":"Exploring the molecular targets for the antidepressant and Antisuicidal effects of ketamine enantiomers by using network pharmacology and molecular docking","volume":"16","author":"Alt\u00ea","year":"2023","journal-title":"Pharmaceuticals (Basel)"},{"issue":"4\u20135","key":"10.1016\/j.pbb.2024.173882_bb0025","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.neubiorev.2005.03.007","article-title":"Stress, depression, and anhedonia: caveats concerning animal models","volume":"29","author":"Anisman","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.pbb.2024.173882_bb0030","author":"atai Life Sciences - Phase 1 Trial"},{"key":"10.1016\/j.pbb.2024.173882_bb0035","author":"atai Life Sciences - Phase 2 Trial"},{"key":"10.1016\/j.pbb.2024.173882_bb0050","first-page":"212","article-title":"The possible role of the Glucose-6-phosphate dehydrogenase enzyme deficiency in the polyneuropathies","volume":"4","author":"Aydemir","year":"2020","journal-title":"The Journal of Basic and Clinical Health Sciences"},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0055","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.cmet.2011.08.016","article-title":"Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation","volume":"14","author":"B\u00e9langer","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.pbb.2024.173882_bb0060","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0006-3223(99)00230-9","article-title":"Antidepressant effects of ketamine in depressed patients","volume":"47","author":"Berman","year":"2000","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.pbb.2024.173882_bb0065","doi-asserted-by":"crossref","unstructured":"Biamonti, G., Ruggiu, M., Saccone, S., Della Valle, G., & Riva, S. (1994). Two homologous genes, originated by duplication, encode the human hnRNP proteins A2 and Al. In nucleic acids research (Vol. 22, issue 11).","DOI":"10.1093\/nar\/22.11.1996"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0070","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1002\/j.1460-2075.1988.tb03227.x","article-title":"Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells","volume":"7","author":"Bond","year":"1988","journal-title":"EMBO J."},{"key":"10.1016\/j.pbb.2024.173882_bb0075","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1146\/annurev.neuro.31.060407.125646","article-title":"Balancing structure and function at hippocampal dendritic spines","volume":"31","author":"Bourne","year":"2008","journal-title":"Annu. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0080","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/bpa.12872","article-title":"Abnormal scaffold attachment factor 1 expression and localization in spinocerebellar ataxias and Huntington\u2019s chorea","volume":"30","author":"Buckner","year":"2020","journal-title":"Brain Pathol."},{"issue":"10","key":"10.1016\/j.pbb.2024.173882_bb0085","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1038\/ni1382","article-title":"The human adaptor SARM negatively regulates adaptor protein TRIF-dependent toll-like receptor signaling","volume":"7","author":"Carty","year":"2006","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.pbb.2024.173882_bb0090","doi-asserted-by":"crossref","unstructured":"Chang, L., Zhang, K., Pu, Y., Qu, Y., Wang, S. ming, Xiong, Z., Ren, Q., Dong, C., Fujita, Y., & Hashimoto, K. (2019). Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine. Pharmacol. Biochem. Behav., 181, 53\u201359. doi:https:\/\/doi.org\/10.1016\/j.pbb.2019.04.008.","DOI":"10.1016\/j.pbb.2019.04.008"},{"issue":"4","key":"10.1016\/j.pbb.2024.173882_bb0095","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1083\/jcb.201008050","article-title":"Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology","volume":"193","author":"Chen","year":"2011","journal-title":"J. Cell Biol."},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0100","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/s42255-019-0043-x","article-title":"NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism","volume":"1","author":"Chen","year":"2019","journal-title":"Nat. Metab."},{"key":"10.1016\/j.pbb.2024.173882_bb0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bbi.2013.05.011","article-title":"A cytokine network involving brain-borne IL-1\u03b2, IL-1ra, IL-18, IL-6, and TNF\u03b1 operates during long-term potentiation and learning","volume":"33","author":"del Rey","year":"2013","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pbb.2024.173882_bb0110","doi-asserted-by":"crossref","DOI":"10.2174\/1389450054021909","article-title":"Glycans and glycan-binding proteins in brain: Galectin-1-induced expression of neurotrophic factors in astrocytes","volume":"6","author":"Endo","year":"2005","journal-title":"In Current Drug Targets"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1161\/ATVBAHA.110.216747","article-title":"Annexin A5 therapy attenuates vascular inflammation and remodeling and improves endothelial function in mice","volume":"31","author":"Ewing","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0120","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1124\/jpet.116.239228","article-title":"Antidepressant potential of (R)-ketamine in rodent models: comparison with (S)-ketamine","volume":"361","author":"Fukumoto","year":"2017","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0130","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.msard.2012.08.002","article-title":"Neural cell adhesion molecules in brain plasticity and disease","volume":"2","author":"Gnanapavan","year":"2013","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.pbb.2024.173882_bb0135","doi-asserted-by":"crossref","unstructured":"Goetzl EJ, Wolkowitz OM, Srihari VH, Reus VI, Goetzl L, Kapogiannis D, Heninger GR, Mellon SH. Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder. Mol. Psychiatry. 2021 Dec;26(12):7355\u20137362. doi: https:\/\/doi.org\/10.1038\/s41380-021-01268-x. Epub 2021 Sep 1. PMID: 34471251; PMCID: PMC8872999.","DOI":"10.1038\/s41380-021-01268-x"},{"issue":"15","key":"10.1016\/j.pbb.2024.173882_bb0140","doi-asserted-by":"crossref","first-page":"6540","DOI":"10.1523\/JNEUROSCI.5087-12.2013","article-title":"Induction of thermal hyperalgesia and synaptic long-term potentiation in the spinal cord Lamina I by TNF-\u03b1 and IL-1\u03b2 is mediated by glial cells","volume":"33","author":"Gruber-Schoffnegger","year":"2013","journal-title":"J. Neurosci."},{"issue":"14","key":"10.1016\/j.pbb.2024.173882_bb0145","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1002\/dneu.20682","article-title":"ERK mediates activity dependent neuronal complexity via sustained activity and CREB-mediated signaling","volume":"68","author":"Ha","year":"2008","journal-title":"Dev. Neurobiol."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0150","doi-asserted-by":"crossref","first-page":"183","DOI":"10.5607\/en.2019.28.2.183","article-title":"Tweety-homolog (Ttyh) family encodes the pore-forming subunits of the swelling-dependent volume-regulated anion channel (VRACswell) in the brain","volume":"28","author":"Han","year":"2019","journal-title":"Experimental Neurobiology"},{"key":"10.1016\/j.pbb.2024.173882_bb0165","doi-asserted-by":"crossref","unstructured":"He, Y., & Smith, R. (2009). Nuclear functions of heterogeneous nuclear ribonucleoproteins A\/B. In cellular and molecular life sciences (Vol. 66, issue 7, pp. 1239\u20131256). doi:https:\/\/doi.org\/10.1007\/s00018-008-8532-1.","DOI":"10.1007\/s00018-008-8532-1"},{"issue":"10","key":"10.1016\/j.pbb.2024.173882_bb0170","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1038\/nn.4114","article-title":"Stress effects on the neural substrates of motivated behavior","volume":"18","author":"Hollon","year":"2015","journal-title":"Nat. Neurosci."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0175","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1159\/000446500","article-title":"Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report","volume":"2","author":"Hough","year":"2016","journal-title":"Complex Psychiatry"},{"issue":"7","key":"10.1016\/j.pbb.2024.173882_bb0180","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1038\/jcbfm.2012.35","article-title":"Updated energy budgets for neural computation in the neocortex and cerebellum","volume":"32","author":"Howarth","year":"2012","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.pbb.2024.173882_bb0190","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.psychres.2011.05.043","article-title":"Altering the expression balance of hnRNP C1 and C2 changes the expression of myelination-related genes","volume":"190","author":"Iwata","year":"2011","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.pbb.2024.173882_bb0195","first-page":"2277","article-title":"To be or not to be: PP2A as a dual player in CNS functions, its role in neurodegeneration, and its interaction with brain insulin signaling","volume":"76","author":"Javadpour","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.pbb.2024.173882_bb0200","doi-asserted-by":"crossref","unstructured":"Jelen, L. A., Young, A. H., & Stone, J. M. (2021). Ketamine: A tale of two enantiomers. In journal of psychopharmacology (Vol. 35, issue 2, pp. 109\u2013123). SAGE publications ltd. doi:https:\/\/doi.org\/10.1177\/0269881120959644.","DOI":"10.1177\/0269881120959644"},{"issue":"11","key":"10.1016\/j.pbb.2024.173882_bb0205","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","article-title":"Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report","volume":"163","author":"John Rush","year":"2006","journal-title":"Am. J. Psychiatry"},{"issue":"9","key":"10.1016\/j.pbb.2024.173882_bb0225","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1084\/jem.20070868","article-title":"MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival","volume":"204","author":"Kim","year":"2007","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.pbb.2024.173882_bb0230","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.biopsych.2013.03.026","article-title":"Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond","volume":"73","author":"Krystal","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0235","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/nar\/gkw377","article-title":"Enrichr: a comprehensive gene set enrichment analysis web server 2016 update","volume":"44","author":"Kuleshov","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.pbb.2024.173882_bb0240","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0009-8981(75)80002-7","article-title":"A new colorimetric method for the determination of NADH\/NADPH dependent glutathione reductase in erythrocytes and in plasma","volume":"58","author":"Kum-Tatt","year":"1975","journal-title":"Clin. Chim. Acta"},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0245","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/1056-8719(94)90075-2","article-title":"Phosphorylation and Dephosphorylation of protein in regulating cellular function","volume":"31","author":"Kurosawa","year":"1994","journal-title":"The Journal of Pharmacological and Toxicological Methods"},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0250","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/575","article-title":"Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase","volume":"19","author":"Labranche","year":"1998","journal-title":"Nat. Genet."},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0255","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00406-020-01110-5","article-title":"Intravenous arketamine for treatment-resistant depression: open-label pilot study","volume":"271","author":"Leal","year":"2021","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.pbb.2024.173882_bb0260","doi-asserted-by":"crossref","unstructured":"Lee, M. T., Peng, W. H., Kan, H. W., Wu, C. C., Wang, D. W., & Ho, Y. C. (2022). Neurobiology of depression: chronic stress alters the glutamatergic system in the brain\u2014focusing on AMPA receptor. In biomedicines (Vol. 10, issue 5). MDPI. doi:https:\/\/doi.org\/10.3390\/biomedicines10051005.","DOI":"10.3390\/biomedicines10051005"},{"issue":"11","key":"10.1016\/j.pbb.2024.173882_bb0265","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1111\/j.1460-9568.2006.05207.x","article-title":"Mouse galectin-1 inhibits the toxicity of glutamate by modifying NR1 NMDA receptor expression","volume":"24","author":"Lekishvili","year":"2006","journal-title":"Eur. J. Neurosci."},{"issue":"10","key":"10.1016\/j.pbb.2024.173882_bb0270","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.biopsych.2016.05.005","article-title":"Glutamate and gamma-aminobutyric acid Systems in the Pathophysiology of major depression and antidepressant response to ketamine","volume":"81","author":"Lener","year":"2017","journal-title":"Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.pbb.2024.173882_bb0275","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/sj.emboj.7600980","article-title":"B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK","volume":"25","author":"Letourneux","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.pbb.2024.173882_bb0280","doi-asserted-by":"crossref","first-page":"97.e1","DOI":"10.1016\/j.neurobiolaging.2020.03.013","article-title":"Cerebrospinal fluid neuronal pentraxin receptor as a biomarker of long-term progression of Alzheimer\u2019s disease: a 24-month follow-up study","volume":"93","author":"Lim","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.pbb.2024.173882_bb0290","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.bbi.2013.12.002","article-title":"Sarm1, a neuronal inflammatory regulator, controls social interaction, associative memory and cognitive flexibility in mice","volume":"37","author":"Lin","year":"2014","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.pbb.2024.173882_bb0300","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1146\/annurev.bi.55.070186.005443","article-title":"The heat-shock response","volume":"55","author":"Lindquist","year":"1986","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.pbb.2024.173882_bb0305","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s12035-020-02137-4","article-title":"Heterogeneous nuclear ribonucleoproteins: implications in Neurological diseases","volume":"58","author":"Low","year":"2021","journal-title":"Mol. Neurobiol."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0310","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1046\/j.1460-9568.2003.02461.x","article-title":"cDNA profiling of epileptogenesis in the rat brain","volume":"17","author":"Lukasiuk","year":"2003","journal-title":"Eur. J. Neurosci."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0315","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.pharmthera.2009.02.010","article-title":"Ketamine and the next generation of antidepressants with a rapid onset of action","volume":"123","author":"Machado-Vieira","year":"2009","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.pbb.2024.173882_bb0320","doi-asserted-by":"crossref","DOI":"10.1186\/1471-244X-9-17","article-title":"Proteome analysis of schizophrenia patients Wernicke\u2019s area reveals an energy metabolism dysregulation","volume":"9","author":"Martins-de-Souza","year":"2009","journal-title":"BMC Psychiatry"},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0325","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2165\/11599770-000000000-00000","article-title":"Ketamine for treatment-resistant unipolar depression: current evidence","volume":"26","author":"Mathew","year":"2012","journal-title":"CNS Drugs"},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0330","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1006\/geno.2001.6548","article-title":"A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo\/\u03b2-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans","volume":"74","author":"Mink","year":"2001","journal-title":"Genomics"},{"issue":"18","key":"10.1016\/j.pbb.2024.173882_bb0335","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1016\/j.febslet.2013.07.027","article-title":"A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A","volume":"587","author":"Nakashima","year":"2013","journal-title":"FEBS Lett."},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0340","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/mp.2014.96","article-title":"Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility","volume":"20","author":"Nasca","year":"2015","journal-title":"Mol. Psychiatry"},{"issue":"8","key":"10.1016\/j.pbb.2024.173882_bb0345","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/da.22535","article-title":"Whither ketamine as an antidepressant: panacea or toxin?","volume":"33","author":"Newport","year":"2016","journal-title":"Depress. Anxiety"},{"issue":"23","key":"10.1016\/j.pbb.2024.173882_bb0350","doi-asserted-by":"crossref","first-page":"4271","DOI":"10.1042\/BCJ20160649","article-title":"The increasing diversity of functions attributed to the SAFB family of RNA-\/DNA-binding proteins","volume":"473","author":"Norman","year":"2016","journal-title":"Biochem. J."},{"key":"10.1016\/j.pbb.2024.173882_bb0355","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2016.65","article-title":"Major depressive disorder","volume":"2","author":"Otte","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.pbb.2024.173882_bb0360","doi-asserted-by":"crossref","unstructured":"Pa\u0142ucha-Poniewiera A, Rafa\u0142o-Uli\u0144ska A, Santocki M, Babii Y, Kaczorowska K. Partial mGlu5 receptor NAM, M-5MPEP, induces rapid and sustained antidepressant-like effects in the BDNF-dependent mechanism and enhances (R)-ketamine action in mice. Pharmacol. Rep. 2024 Jun;76(3):504\u2013518. doi: https:\/\/doi.org\/10.1007\/s43440-024-00588-3. Epub 2024 Apr 18. PMID: 38632187.","DOI":"10.1007\/s43440-024-00588-3"},{"key":"10.1016\/j.pbb.2024.173882_bb0365","doi-asserted-by":"crossref","unstructured":"Papp, M., Gruca, P., Lason, M., Litwa, E., Solecki, W., & Willner, P. (2020). AMPA receptors mediate the pro-cognitive effects of electrical and optogenetic stimulation of the medial prefrontal cortex in antidepressant non-responsive Wistar\u2013Kyoto rats. J. Psychopharmacol., 34(12), 1418\u20131430. doi:https:\/\/doi.org\/10.1177\/0269881120967857.","DOI":"10.1177\/0269881120967857"},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0375","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.neuron.2015.02.020","article-title":"Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons","volume":"85","author":"Pelkey","year":"2015","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0380","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1002\/eji.200940034","article-title":"SARM inhibits both TRIF- and MyD88-mediated AP-1 activation","volume":"40","author":"Peng","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.pbb.2024.173882_bb0385","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1146\/annurev-clinpsy-050212-185606","article-title":"Depression, stress, and anhedonia: toward a synthesis and integrated model","volume":"10","author":"Pizzagalli","year":"2014","journal-title":"Annu. Rev. Clin. Psychol."},{"issue":"11","key":"10.1016\/j.pbb.2024.173882_bb0390","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1007\/s11064-010-0234-z","article-title":"Galectin-1 enhances astrocytic BDNF production and improves functional outcome in rats following ischemia","volume":"35","author":"Qu","year":"2010","journal-title":"Neurochem. Res."},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0395","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/YCO.0b013e32834b9db6","article-title":"Inflammatory mechanisms in major depressive disorder","volume":"24","author":"Raedler","year":"2011","journal-title":"Curr. Opin. Psychiatry"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0400","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-35912-z","article-title":"Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression","volume":"13","author":"Rampersaud","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pbb.2024.173882_bb0405","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jad.2015.11.052","article-title":"Depression and telomere length: A meta-analysis","volume":"191","author":"Ridout","year":"2016","journal-title":"J. Affect. Disord."},{"issue":"12","key":"10.1016\/j.pbb.2024.173882_bb0410","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0145938","article-title":"TIPRL inhibits protein phosphatase 4 activity and promotes H2AX phosphorylation in the DNA damage response","volume":"10","author":"Rosales","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.pbb.2024.173882_bb0415","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/nrn3381","article-title":"The brain reward circuitry in mood disorders","volume":"14","author":"Russo","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.pbb.2024.173882_bb0420","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.112862","article-title":"Impaired emotional response to stress in mice lacking galectin-1 or galectin-3","volume":"220","author":"Sartim","year":"2020","journal-title":"Physiol. Behav."},{"issue":"4","key":"10.1016\/j.pbb.2024.173882_bb0425","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/glycob\/cwh043","article-title":"Galectin-1 induces astrocyted differentiation, which leads to production of brain-derived neurotrophic factor","volume":"14","author":"Sasaki","year":"2004","journal-title":"Glycobiology"},{"key":"10.1016\/j.pbb.2024.173882_bb0430","doi-asserted-by":"crossref","unstructured":"Scotton, E., Antqueviezc, B., Vasconcelos, M. F. de, Dalpiaz, G., Paul G\u00e9a, L., Ferraz Goularte, J., Colombo, R., & Ribeiro Rosa, A. (2022). Is (R)-ketamine a potential therapeutic agent for treatment-resistant depression with less detrimental side effects? A review of molecular mechanisms underlying ketamine and its enantiomers. Biochem. Pharmacol., 198. doi:https:\/\/doi.org\/10.1016\/j.bcp.2022.114963.","DOI":"10.1016\/j.bcp.2022.114963"},{"key":"10.1016\/j.pbb.2024.173882_bb0435","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2023.173523","article-title":"Differentially regulated targets in the fast-acting antidepressant effect of (R)-ketamine: A systems biology approach","volume":"223","author":"Scotton","year":"2023","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"12","key":"10.1016\/j.pbb.2024.173882_bb0440","doi-asserted-by":"crossref","first-page":"6804","DOI":"10.3390\/ijms25126804","article-title":"(R)-(\u2212)-ketamine: the promise of a novel treatment for psychiatric and Neurological disorders","volume":"25","author":"Shafique","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.pbb.2024.173882_bb0445","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1146\/annurev.biochem.76.060805.160029","article-title":"The postsynaptic architecture of excitatory synapses: A more quantitative view","volume":"76","author":"Sheng","year":"2007","journal-title":"Annu. Rev. Biochem."},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0450","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S2215-0366(17)30272-9","article-title":"Side-effects associated with ketamine use in depression: a systematic review","volume":"5","author":"Short","year":"2018","journal-title":"Lancet Psychiatry"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0460","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.tins.2018.09.008","article-title":"From stress to anhedonia: molecular processes through functional circuits","volume":"42","author":"Stanton","year":"2019","journal-title":"Trends Neurosci."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0465","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.immuni.2012.05.023","article-title":"Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration","volume":"37","author":"Starossom","year":"2012","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0470","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.neulet.2010.07.045","article-title":"Cloning of expressed sequence tags (ESTs) representing putative epileptogenesis-related genes and the localization of their expression in the normal brain","volume":"482","author":"Stefaniuk","year":"2010","journal-title":"Neurosci. Lett."},{"issue":"5","key":"10.1016\/j.pbb.2024.173882_bb0475","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1111\/j.1471-4159.2010.07023.x","article-title":"Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology","volume":"115","author":"Stefaniuk","year":"2010","journal-title":"J. Neurochem."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0485","doi-asserted-by":"crossref","first-page":"778","DOI":"10.4049\/jimmunol.176.2.778","article-title":"Galectin-3 and Galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death","volume":"176","author":"Stillman","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.pbb.2024.173882_bb0490","doi-asserted-by":"crossref","DOI":"10.1186\/1744-9081-7-9","article-title":"Update in the methodology of the chronic stress paradigm: internal control matters","volume":"7","author":"Strekalova","year":"2011","journal-title":"Behav. Brain Funct."},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0495","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.neuron.2018.09.040","article-title":"Towards an understanding of synapse formation","volume":"100","author":"S\u00fcdhof","year":"2018","journal-title":"Neuron"},{"issue":"D1","key":"10.1016\/j.pbb.2024.173882_bb0500","doi-asserted-by":"crossref","first-page":"D607","DOI":"10.1093\/nar\/gky1131","article-title":"STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets","volume":"47","author":"Szklarczyk","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"9","key":"10.1016\/j.pbb.2024.173882_bb0510","doi-asserted-by":"crossref","first-page":"14285","DOI":"10.1002\/jcb.29004","article-title":"Neuroprotection by glucose-6-phosphate dehydrogenase and the pentose phosphate pathway","volume":"120","author":"Tang","year":"2019","journal-title":"J. Cell. Biochem."},{"issue":"8","key":"10.1016\/j.pbb.2024.173882_bb0515","doi-asserted-by":"crossref","DOI":"10.3390\/biology10080712","article-title":"Hnrnp a\/b proteins: An encyclopedic assessment of their roles in homeostasis and disease","volume":"10","author":"Thibault","year":"2021","journal-title":"Biology"},{"issue":"4","key":"10.1016\/j.pbb.2024.173882_bb0520","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.gendis.2017.09.001","article-title":"Glucose 6 phosphatase dehydrogenase (G6PD) and neurodegenerative disorders: mapping diagnostic and therapeutic opportunities","volume":"4","author":"Tiwari","year":"2017","journal-title":"Genes and Diseases"},{"issue":"22","key":"10.1016\/j.pbb.2024.173882_bb0525","doi-asserted-by":"crossref","first-page":"20059","DOI":"10.1074\/jbc.M212988200","article-title":"SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor","volume":"278","author":"Townson","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.pbb.2024.173882_bb0530","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/S2215-0366(19)30394-3","article-title":"Esketamine for treatment-resistant depression: seven concerns about efficacy and FDA approval","volume":"6","author":"Turner","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.pbb.2024.173882_bb0535","author":"U.S. Food and Drug Administration"},{"issue":"2","key":"10.1016\/j.pbb.2024.173882_bb0540","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.mehy.2015.05.006","article-title":"Glucose-6-phosphate dehydrogenase deficiency and Alzheimer\u2019s disease: partners in crime?","volume":"85","author":"Ulusu","year":"2015","journal-title":"The hypothesis. Medical Hypotheses"},{"issue":"36","key":"10.1016\/j.pbb.2024.173882_bb0545","doi-asserted-by":"crossref","first-page":"30240","DOI":"10.1074\/jbc.M112.374405","article-title":"Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons","volume":"287","author":"Urbanska","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pbb.2024.173882_bb0550","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/S0896-6273(02)00717-1","article-title":"Signaling mechanisms underlying reversible, activity-dependent dendrite formation","volume":"34","author":"Vaillant","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.pbb.2024.173882_bb0555","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0022-3956(99)00026-6","article-title":"Elevated concentration of N-CAM VASE isoforms in schizophrenia","volume":"34","author":"Vawter","year":"2020","journal-title":"Journal of Psychitryc Research"},{"issue":"4","key":"10.1016\/j.pbb.2024.173882_bb0560","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1002\/ijc.28426","article-title":"Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity","volume":"134","author":"Verschuere","year":"2014","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.pbb.2024.173882_bb0565","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2147\/NDT.S198774","article-title":"Management of treatment-resistant depression: challenges and strategies","volume":"16","author":"Voineskos","year":"2020","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0570","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0924-977X(96)00042-9","article-title":"Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET)","volume":"7","author":"Vollenweider","year":"1997","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"3","key":"10.1016\/j.pbb.2024.173882_bb0580","doi-asserted-by":"crossref","DOI":"10.3390\/cancers11030334","article-title":"Heterogeneous nuclear ribonucleoproteins a1 and a2 function in telomerase-dependent maintenance of telomeres","volume":"11","author":"Wang","year":"2019","journal-title":"Cancers"},{"issue":"7","key":"10.1016\/j.pbb.2024.173882_bb0585","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1523\/JNEUROSCI.3056-15.2016","article-title":"Histone modification of Nedd4 ubiquitin ligase controls the loss of AMPA receptors and cognitive impairment induced by repeated stress","volume":"36","author":"Wei","year":"2016","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.pbb.2024.173882_bb0590","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1093\/cercor\/bhx104","article-title":"Chemicogenetic restoration of the prefrontal cortex to amygdala pathway ameliorates stress-induced deficits","volume":"28","author":"Wei","year":"2018","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.pbb.2024.173882_bb0595","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ynstr.2016.08.002","article-title":"The chronic mild stress (CMS) model of depression: history, evaluation and usage","volume":"6","author":"Willner","year":"2017","journal-title":"Neurobiology of Stress"},{"key":"10.1016\/j.pbb.2024.173882_bb0600","series-title":"Depression and Other Common Mental Disorders Global Health Estimates","author":"World Health Organization","year":"2017"},{"issue":"9","key":"10.1016\/j.pbb.2024.173882_bb0605","article-title":"R-ketamine: A rapid-onset and sustained antidepressant without psychotomimetic side effects. Translational","volume":"5","author":"Yang","year":"2015","journal-title":"Psychiatry"},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0610","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41398-019-0624-1","article-title":"Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites","volume":"9","author":"Yang","year":"2019","journal-title":"Transl. Psychiatry"},{"issue":"41","key":"10.1016\/j.pbb.2024.173882_bb0615","doi-asserted-by":"crossref","first-page":"17113","DOI":"10.1074\/jbc.M117.810309","article-title":"Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions","volume":"292","author":"Yao","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.pbb.2024.173882_bb0620","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1038\/s41380-021-01377-7","article-title":"Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine","volume":"27","author":"Yao","year":"2022","journal-title":"Mol. Psychiatry"},{"issue":"7604","key":"10.1016\/j.pbb.2024.173882_bb0625","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature17998","article-title":"NMDAR inhibition-independent antidepressant actions of ketamine metabolites","volume":"533","author":"Zanos","year":"2016","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.pbb.2024.173882_bb0630","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/archpsyc.63.8.856","article-title":"A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression","volume":"63","author":"Zarate","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.pbb.2024.173882_bb0635","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.pbb.2013.11.033","article-title":"R (\u2212)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine","volume":"116","author":"Zhang","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.pbb.2024.173882_bb0640","article-title":"Lack of metabolism in (R)-ketamine\u2019s antidepressant actions in a chronic social defeat stress model","volume":"8","author":"Zhang","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pbb.2024.173882_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2019.103236","article-title":"The role of ANXA5 in DBP-induced oxidative stress through ERK\/Nrf2 pathway","volume":"72","author":"Zhang","year":"2019","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"1\u20133","key":"10.1016\/j.pbb.2024.173882_bb0650","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.schres.2014.09.036","article-title":"Promoter variant rs2301228 on the neural cell adhesion molecule 1 gene confers risk of schizophrenia in Han Chinese","volume":"160","author":"Zhang","year":"2014","journal-title":"Schizophr. Res."}],"container-title":["Pharmacology Biochemistry and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009130572400176X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009130572400176X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T13:51:32Z","timestamp":1733233892000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009130572400176X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":113,"alternative-id":["S009130572400176X"],"URL":"https:\/\/doi.org\/10.1016\/j.pbb.2024.173882","relation":{},"ISSN":["0091-3057"],"issn-type":[{"value":"0091-3057","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular signature underlying (R)-ketamine rapid antidepressant response on anhedonic-like behavior induced by sustained exposure to stress","name":"articletitle","label":"Article Title"},{"value":"Pharmacology Biochemistry and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pbb.2024.173882","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"173882"}}