{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:20:27Z","timestamp":1791393627380,"version":"4.3.3"},"reference-count":52,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Science Foundation"},{"DOI":"10.13039\/100012009","name":"United Soybean Board","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012009","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Plant Biology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.pbi.2013.06.019","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T13:31:30Z","timestamp":1373981490000},"page":"527-533","source":"Crossref","is-referenced-by-count":230,"title":["Systemic signaling during plant defense"],"prefix":"10.1016","volume":"16","author":[{"given":"Aardra","family":"Kachroo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume P","family":"Robin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pbi.2013.06.019_bib0005","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0042-6822(61)90319-1","article-title":"Systemic acquired resistance induced by localized virus infections in plants","volume":"14","author":"Ross","year":"1961","journal-title":"Virology"},{"key":"10.1016\/j.pbi.2013.06.019_bib0010","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1749-6632.1987.tb29529.x","article-title":"Translocated signals for plant immunization","volume":"494","author":"Kuc","year":"1987","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0015","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1104\/pp.111.187468","article-title":"Next-generation systemic acquired resistance","volume":"158","author":"Luna","year":"2012","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0020","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1104\/pp.111.191593","article-title":"Descendants of primed Arabidopsis plants exhibit resistance to biotic stress","volume":"158","author":"Slaughter","year":"2012","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0025","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.tplants.2012.05.011","article-title":"SOS-too many signals for systemic acquired resistance?","volume":"17","author":"Dempsey","year":"2012","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_bib0030","first-page":"11","article-title":"Systemic acquired resistance: turning local infection into global defense","volume":"14","author":"Fu","year":"2013","journal-title":"Annu Rev Plant Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0035","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3389\/fpls.2013.00030","article-title":"Long-distance communication and signal amplification in systemic acquired resistance","volume":"4","author":"Shah","year":"2013","journal-title":"Front Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_bib0040","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/jipb.12041","article-title":"The plant vascular system: evolution, development and functions","volume":"55","author":"Lucas","year":"2013","journal-title":"J Integr Plant Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0045","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1104\/pp.111.182089","article-title":"Brush and spray: a high-throughput systemic acquired resistance assay suitable for large-scale genetic screening","volume":"157","author":"Jing","year":"2011","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0050","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.1105\/tpc.112.103564","article-title":"Pipecolic acid, an endogenous mediator of defense amplification and priming, is a critical regulator of inducible plant immunity","volume":"24","author":"N\u00e1varov\u00e1","year":"2012","journal-title":"Plant Cell"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0055","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1104\/pp.110.171694","article-title":"Interconnection between methyl salicylate and lipid-based long-distance signaling during the development of systemic acquired resistance in Arabidopsis and tobacco","volume":"155","author":"Liu","year":"2011","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0060","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/j.1365-313X.1994.00715.x","article-title":"Biologically induced systemic acquired resistance in Arabidopsis thaliana","volume":"5","author":"Cameron","year":"1994","journal-title":"Plant J"},{"key":"10.1016\/j.pbi.2013.06.019_bib0065","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.cub.2011.12.015","article-title":"The HSF-like transcription factor TBF1 is a major molecular switch for plant growth-to-defense transition","volume":"22","author":"Pajerowska-Mukhtar","year":"2012","journal-title":"Curr Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0070","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-313X.2004.02200.x","article-title":"A key role for ALD1 in activation of local and systemic defenses in Arabidopsis","volume":"40","author":"Song","year":"2004","journal-title":"Plant J"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0075","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.celrep.2013.03.030","article-title":"A feed-back regulatory loop between glycerol-3-phosphate and lipid transfer proteins DIR1 and AZI1 mediates azelaic acid-induced systemic immunity","volume":"3","author":"Yu","year":"2013","journal-title":"Cell Reports"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0080","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1126\/science.1170025","article-title":"Priming in systemic plant immunity","volume":"324","author":"Jung","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0085","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-313X.2012.04981.x","article-title":"An abietane diterpenoid is a potent activator of systemic acquired resistance","volume":"71","author":"Chaturvedi","year":"2012","journal-title":"Plant J"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0090","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/ng.798","article-title":"Glycerol-3-phosphate is a critical mobile inducer of systemic immunity in plants","volume":"43","author":"Chanda","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0095","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1126\/science.1147113","article-title":"Methyl salicylate is a critical mobile signal for plant systemic acquired resistance","volume":"318","author":"Park","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.pbi.2013.06.019_bib0100","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1105\/tpc.108.063164","article-title":"Methyl salicylate production and jasmonate signaling are not essential for systemic acquired resistance in Arabidopsis","volume":"21","author":"Attaran","year":"2009","journal-title":"Plant Cell"},{"key":"10.1016\/j.pbi.2013.06.019_bib0105","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1104\/pp.111.187773","article-title":"The extent to which methyl salicylate is required for signaling systemic acquired resistance is dependent on exposure to light after infection","volume":"157","author":"Liu","year":"2011","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0110","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/385718a0","article-title":"Airborne signalling by methyl salicylate in plant pathogen resistance","volume":"385","author":"Shulaev","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.pbi.2013.06.019_bib0115","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1073\/pnas.0409227102","article-title":"Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity","volume":"102","author":"Forouhar","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.pbi.2013.06.019_bib0120","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nature00962","article-title":"A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis","volume":"419","author":"Maldonado","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.pbi.2013.06.019_bib0125","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1104\/pp.112.202846","article-title":"Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid","volume":"160","author":"Zoeller","year":"2012","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0130","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/1471-2229-11-125","article-title":"Localization of DIR1 at the tissue, cellular and subcellular levels during Systemic Acquired Resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters","volume":"11","author":"Champigny","year":"2011","journal-title":"BMC Plant Biol"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0135","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.chom.2009.01.001","article-title":"An intact cuticle in distal tissues is essential for the induction of systemic acquired resistance in plants","volume":"5","author":"Xia","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0140","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1104\/pp.110.161646","article-title":"The glabra1 mutation affects cuticle formation and plant responses to microbes","volume":"154","author":"Xia","year":"2010","journal-title":"Plant Physiol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0145","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev-phyto-080508-081820","article-title":"Fatty Acid-derived signals in plant defense","volume":"47","author":"Kachroo","year":"2009","journal-title":"Annu Rev Phytopathol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0150","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1016\/j.phytochem.2006.09.011","article-title":"The lipid polyester composition of Arabidopsis thaliana and Brassica napus seeds","volume":"67","author":"Molina","year":"2006","journal-title":"Phytochemistry"},{"key":"10.1016\/j.pbi.2013.06.019_bib0155","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.tplants.2008.03.003","article-title":"Building lipid barriers: biosynthesis of cutin and suberin","volume":"13","author":"Pollard","year":"2008","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_bib0160","doi-asserted-by":"crossref","first-page":"224","DOI":"10.3389\/fpls.2012.00224","article-title":"Acyl CoA binding proteins are required for cuticle formation and plant responses to microbes","volume":"3","author":"Xia","year":"2012","journal-title":"Front Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_bib0165","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/35107108","article-title":"Isochorismate synthase is required to synthesize salicylic acid for plant defence","volume":"414","author":"Wildermuth","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.pbi.2013.06.019_bib0170","doi-asserted-by":"crossref","first-page":"18220","DOI":"10.1073\/pnas.1005225107","article-title":"Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors","volume":"107","author":"Zhang","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.pbi.2013.06.019_bib0175","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1105\/tpc.014894","article-title":"Knockout analysis of Arabidopsis transcription factors TGA2, TGA5, and TGA6 reveals their redundant and essential roles in systemic acquired resistance","volume":"15","author":"Zhang","year":"2003","journal-title":"Plant Cell"},{"key":"10.1016\/j.pbi.2013.06.019_bib0180","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.pbi.2004.07.005","article-title":"NPR1, all things considered","volume":"7","author":"Dong","year":"2004","journal-title":"Curr Opin Plant Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0185","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.pbi.2004.05.006","article-title":"NPR1: the spider in the web of induced resistance signaling pathways","volume":"7","author":"Pieterse","year":"2004","journal-title":"Curr Opin Plant Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0190","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.1371\/journal.ppat.0020123","article-title":"A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants","volume":"2","author":"Wang","year":"2006","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.pbi.2013.06.019_bib0195","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.cell.2009.03.038","article-title":"Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity","volume":"137","author":"Spoel","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0200","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.celrep.2012.05.008","article-title":"The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid","volume":"1","author":"Wu","year":"2012","journal-title":"Cell Reports"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0205","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nature11162","article-title":"NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants","volume":"486","author":"Fu","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.pbi.2013.06.019_bib0210","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1073\/pnas.0605423104","article-title":"Arabidopsis systemic immunity uses conserved defense signaling pathways and is mediated by jasmonates","volume":"104","author":"Truman","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.pbi.2013.06.019_bib0215","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1105\/tpc.112.103317","article-title":"The Arabidopsis mediator complex subunit 16 positively regulates salicylate-mediated systemic acquired resistance and jasmonate\/ethylene-induced defense pathways","volume":"24","author":"Zhang","year":"2012","journal-title":"Plant Cell"},{"key":"10.1016\/j.pbi.2013.06.019_bib0220","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1364-3703.2012.00842.x","article-title":"The Botrytis cinerea cerato-platanin BcSpl1 is a potent inducer of systemic acquired resistance (SAR) in tobacco and generates a wave of salicylic acid expanding from the site of application","volume":"14","author":"Fr\u00edas","year":"2013","journal-title":"Mol Plant Pathol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0225","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1006\/pmpp.1999.0214","article-title":"Accumulation of salicylic acid and PR-1 gene transcripts in relation to the systemic acquired resistance (SAR) response induced by Pseudomonas syringae pv. tomato in Arabidopsis","volume":"55","author":"Cameron","year":"1999","journal-title":"Physiol Mol Plant Pathol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0230","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S1360-1385(02)02244-6","article-title":"Priming in plant-pathogen interactions","volume":"7","author":"Conrath","year":"2002","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_bib0235","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.tplants.2011.06.004","article-title":"Molecular aspects of defence priming","volume":"16","author":"Conrath","year":"2011","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.pbi.2013.06.019_sbref0240","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/embor.2010.186","article-title":"Chromatin modification acts as a memory for systemic acquired resistance in the plant stress response","volume":"12","author":"Jaskiewicz","year":"2011","journal-title":"EMBO Rep"},{"key":"10.1016\/j.pbi.2013.06.019_bib0245","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1365-313X.2009.03875.x","article-title":"Antagonism between salicylic and abscisic acid reflects early host-pathogen conflict and moulds plant defence responses","volume":"59","author":"de Torres-Zabala","year":"2009","journal-title":"Plant J"},{"key":"10.1016\/j.pbi.2013.06.019_bib0250","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.cub.2011.04.045","article-title":"Chemical genetics reveals negative regulation of abscisic acid signaling by a plant immune response pathway","volume":"21","author":"Kim","year":"2011","journal-title":"Curr Biol"},{"key":"10.1016\/j.pbi.2013.06.019_bib0255","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1105\/tpc.107.054296","article-title":"Antagonistic interaction between systemic acquired resistance and the abscisic acid-mediated abiotic stress response in Arabidopsis","volume":"20","author":"Yasuda","year":"2008","journal-title":"Plant Cell"},{"key":"10.1016\/j.pbi.2013.06.019_bib0260","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1104\/pp.110.158972","article-title":"Abscisic acid deficiency causes changes in cuticle permeability and pectin composition that influence tomato resistance to Botrytis cinerea","volume":"154","author":"Curvers","year":"2010","journal-title":"Plant Physiol"}],"container-title":["Current Opinion in Plant Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369526613001027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1369526613001027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T18:10:23Z","timestamp":1588961423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1369526613001027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S1369526613001027"],"URL":"https:\/\/doi.org\/10.1016\/j.pbi.2013.06.019","relation":{},"ISSN":["1369-5266"],"issn-type":[{"value":"1369-5266","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}