{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:33:11Z","timestamp":1790357591467,"version":"4.1.0"},"reference-count":96,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Progress in Cardiovascular Diseases"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.pcad.2023.08.003","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:32:12Z","timestamp":1693341132000},"page":"46-52","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Invasive therapies for symptomatic obstructive hypertrophic cardiomyopathy"],"prefix":"10.1016","volume":"80","author":[{"given":"Nandini","family":"Mehra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Veselka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Smedira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind Y.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pcad.2023.08.003_bb0005","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/s12265-009-9147-0","article-title":"Sudden death in hypertrophic cardiomyopathy","volume":"2","author":"Maron","year":"2009","journal-title":"J Cardiovasc Transl Res"},{"key":"10.1016\/j.pcad.2023.08.003_bb0010","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/eurheartj\/4.suppl_F.135","article-title":"Hypertrophic cardiomyopathy: a common cause of sudden death in the young competitive athlete","volume":"4","author":"Maron","year":"1983","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0015","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1161\/01.CIR.92.4.785","article-title":"Prevalence of hypertrophic cardiomyopathy in a general population of young adults: echocardiographic analysis of 4111 subjects in the CARDIA study","volume":"92","author":"Maron","year":"1995","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0020","first-page":"22","article-title":"Genetic testing in patients with hypertrophic cardiomyopathy","author":"Bonaventura","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.pcad.2023.08.003_bb0025","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(12)60397-3","article-title":"Hypertrophic cardiomyopathy","volume":"381","author":"Maron","year":"2013","journal-title":"The Lancet"},{"key":"10.1016\/j.pcad.2023.08.003_bb0030","first-page":"120","article-title":"Hypertrophic cardiomyopathy: a review","author":"Hensley","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0035","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jacc.2021.11.021","article-title":"Management of Hypertrophic Cardiomyopathy: JACC state-of-the-art review","volume":"79","author":"Maron","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0040","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1136\/hrt.22.3.403","article-title":"Obstructive cardiomyopathy simulating aortic stenosis","volume":"22","author":"Goodwin","year":"1960","journal-title":"Br Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0045","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/00000658-196108000-00003","article-title":"Surgical treatment of idiopathic hypertrophic subaortic stenosis: technic and hemodynamic results of subaortic ventriculomyotomy","volume":"154","author":"Morrow","year":"1961","journal-title":"Ann Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0050","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0003-4975(94)92268-3","article-title":"Extended myectomy for hypertrophic obstructive cardiomyopathy","volume":"58","author":"Messmer","year":"1994","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0055","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1161\/01.CIR.92.9.122","article-title":"Long-term clinical and echocardiographic follow-up after surgical correction of hypertrophic obstructive cardiomyopathy with extended Myectomy and reconstruction of the Subvalvular mitral apparatus","volume":"92","author":"Schoendube","year":"1995","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0060","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.115.003132","article-title":"Left ventricular outflow tract obstruction in hypertrophic cardiomyopathy patients without severe septal hypertrophy: implications of mitral valve and papillary muscle abnormalities assessed using cardiac magnetic resonance and echocardiography","volume":"8","author":"Patel","year":"2015","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.pcad.2023.08.003_bb0065","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jtcvs.2009.10.045","article-title":"Characteristics and surgical outcomes of symptomatic patients with hypertrophic cardiomyopathy with abnormal papillary muscle morphology undergoing papillary muscle reorientation","volume":"140","author":"Kwon","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0070","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/j.jcmg.2019.09.020","article-title":"The hypertrophic cardiomyopathy phenotype viewed through the prism of multimodality imaging: clinical and etiologic implications","volume":"13","author":"Rowin","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.pcad.2023.08.003_bb0075","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jtcvs.2009.10.045","article-title":"Characteristics and surgical outcomes of symptomatic patients with hypertrophic cardiomyopathy with abnormal papillary muscle morphology undergoing papillary muscle reorientation","volume":"140","author":"Kwon","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0080","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1161\/01.CIR.24.4.739","article-title":"Surgical relief of diffuse Subvalvular aortic stenosis","volume":"24","author":"Kirklin","year":"1961","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0085","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1161\/01.CIR.32.1.52","article-title":"Results of surgical treatment of patients with diffuse Subvalvular aortic stenosis","volume":"32","author":"Frye","year":"1965","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0090","first-page":"10","article-title":"Surgery for hypertrophic obstructive cardiomyopathy: comprehensive LVOT management beyond septal Myectomy","author":"Affronti","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.pcad.2023.08.003_bb0095","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.amjcard.2022.06.007","article-title":"Ventricular septal Myectomy for obstructive hypertrophic cardiomyopathy (analysis spanning 60 years of practice): AJC expert panel","volume":"180","author":"Maron","year":"2022","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0100","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1053\/j.optechstcvs.2012.04.002","article-title":"Transaortic extended septal Myectomy for hypertrophic cardiomyopathy","volume":"17","author":"Schaff","year":"2012","journal-title":"Operat Techni Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0105","doi-asserted-by":"crossref","first-page":"423","DOI":"10.21037\/acs.2017.06.03","article-title":"The surgical management of obstructive hypertrophic cardiomyopathy: the RPR procedure-resection, plication, release","volume":"6","author":"Swistel","year":"2017","journal-title":"Annal Cardiothorac Surge"},{"key":"10.1016\/j.pcad.2023.08.003_bb0110","first-page":"1415","article-title":"Low incidence of procedure-related major adverse cardiac events after alcohol septal ablation for symptomatic hypertrophic obstructive cardiomyopathy","volume":"29","author":"Veselka","year":"2013","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0115","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.jtcvs.2015.07.063","article-title":"Symptom assessment and exercise impairment in surgical decision making in hypertrophic obstructive cardiomyopathy: relationship to outcomes","volume":"150","author":"Desai","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0120","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.jtcvs.2015.08.056","article-title":"Septal myectomy in context: clinical acumen and procedural expertise","volume":"150","author":"Ommen","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0125","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.athoracsur.2008.01.061","article-title":"Mitral valve abnormalities in hypertrophic cardiomyopathy: echocardiographic features and surgical outcomes","volume":"85","author":"Kaple","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0130","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1016\/j.jacc.2015.07.069","article-title":"Transaortic chordal cutting: mitral valve repair for obstructive hypertrophic cardiomyopathy with mild septal hypertrophy","volume":"66","author":"Ferrazzi","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0135","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jtcvs.2003.09.040","article-title":"Extended septal myectomy for hypertrophic obstructive cardiomyopathy with anomalous mitral papillary muscles or chordae","volume":"127","author":"Minakata","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0140","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jtcvs.2019.03.088","article-title":"Apical myectomy for patients with hypertrophic cardiomyopathy and advanced heart failure","volume":"159","author":"Nguyen","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0145","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1540-8191.2012.01475.x","article-title":"Transapical approach for apical Myectomy and relief of Midventricular obstruction in hypertrophic cardiomyopathy","volume":"27","author":"Said","year":"2012","journal-title":"J Card Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0150","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.jtcvs.2009.07.079","article-title":"Apical myectomy: a new surgical technique for management of severely symptomatic patients with apical hypertrophic cardiomyopathy","volume":"139","author":"Schaff","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0155","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1016\/j.jtcvs.2017.10.054","article-title":"Combined transaortic and transapical approach to septal myectomy in patients with complex hypertrophic cardiomyopathy","volume":"155","author":"Hang","year":"2018","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0160","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.athoracsur.2022.03.027","article-title":"Apical Myectomy in HCM: time to let the rubber of the operation meet the road of a randomized trial","volume":"114","author":"Smedira","year":"2022","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0165","doi-asserted-by":"crossref","first-page":"353","DOI":"10.21037\/acs.2017.07.07","article-title":"Results of surgical septal myectomy for obstructive hypertrophic cardiomyopathy: the tufts experience","volume":"6","author":"Rastegar","year":"2017","journal-title":"Annal Cardiothorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0170","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1161\/CIRCULATIONAHA.112.000849","article-title":"Predictors of long-term outcomes in symptomatic hypertrophic obstructive cardiomyopathy patients undergoing surgical relief of left ventricular outflow tract obstruction","volume":"128","author":"Desai","year":"2013","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.athoracsur.2018.03.039","article-title":"Determinants of reverse remodeling of the left atrium after Transaortic Myectomy","volume":"106","author":"Nguyen","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0180","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.jacc.2019.05.053","article-title":"Conduction abnormalities and long-term mortality following septal Myectomy in patients with obstructive hypertrophic cardiomyopathy","volume":"74","author":"Cui","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0185","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.7293","article-title":"Association of Septal Myectomy with Quality of life in patients with left ventricular outflow tract obstruction from hypertrophic cardiomyopathy","volume":"5","author":"Desai","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.pcad.2023.08.003_bb0190","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.carrev.2009.11.003","article-title":"The history of alcohol septal ablation","volume":"11","author":"Kuhn","year":"2010","journal-title":"Cardiovas Revascularizat Med\u202f: Includi Mol Intervent"},{"key":"10.1016\/j.pcad.2023.08.003_bb0195","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0140-6736(95)91267-3","article-title":"Non-surgical myocardial reduction for hypertrophic obstructive cardiomyopathy","volume":"346","author":"Sigwart","year":"1995","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.pcad.2023.08.003_bb0200","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/S0140-6736(16)31321-6","article-title":"Hypertrophic obstructive cardiomyopathy","volume":"389","author":"Veselka","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.pcad.2023.08.003_bb0205","doi-asserted-by":"crossref","first-page":"e2194","DOI":"10.4244\/EIJ-D-15-00159","article-title":"Computed tomography angiography planning identifies the target vessel for optimum infarct location and improves clinical outcome in alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"12","author":"Cooper","year":"2017","journal-title":"EuroIntervent\u202f: J EuroPCR Collaborat Work Group Intervent Cardiol Euro Soc Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0210","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.amjcard.2004.10.050","article-title":"Effects of varying ethanol dosing in percutaneous septal ablation for obstructive hypertrophic cardiomyopathy on early hemodynamic changes","volume":"95","author":"Veselka","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0215","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1016\/j.jacc.2018.09.064","article-title":"Survival after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy","volume":"72","author":"Batzner","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0220","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1016\/j.jacc.2011.06.073","article-title":"Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. A multicenter north American registry","volume":"58","author":"Nagueh","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0225","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/eurheartj\/ehv693","article-title":"Long-term clinical outcome after alcohol septal ablation for obstructive hypertrophic cardiomyopathy: results from the euro-ASA registry","volume":"37","author":"Veselka","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0230","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1016\/j.jcin.2022.06.034","article-title":"Outcomes of patients with hypertrophic obstructive cardiomyopathy and pacemaker implanted after alcohol septal ablation","volume":"15","author":"Veselka","year":"2022","journal-title":"J Am Coll Cardiol Intv"},{"key":"10.1016\/j.pcad.2023.08.003_bb0235","first-page":"101","article-title":"Early outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a European multicenter and multinational study","volume":"84","author":"Veselka","year":"2014","journal-title":"Catheterizat Cardiovasc Intervent\u202f: Off J Soc Cardiac Angiograph & Intervent"},{"key":"10.1016\/j.pcad.2023.08.003_bb0240","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1253\/circj.70.880","article-title":"Age-related hemodynamic and morphologic differences in patients undergoing alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"70","author":"Veselka","year":"2006","journal-title":"Circulat J\u202f: Off J Japan Circulat Soc"},{"key":"10.1016\/j.pcad.2023.08.003_bb0245","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1016\/S0140-6736(95)91954-6","article-title":"Non-surgical myocardial reduction for hypertrophic obstructive cardiomyopathy","volume":"346","author":"Goodwin","year":"1995","journal-title":"The Lancet"},{"key":"10.1016\/j.pcad.2023.08.003_bb0250","first-page":"e533","article-title":"2020 AHA\/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"142","author":"Ommen","year":"2020","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0255","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1161\/CIRCULATIONAHA.111.076257","article-title":"Survival after alcohol septal ablation for obstructive hypertrophic cardiomyopathy","volume":"126","author":"Sorajja","year":"2012","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0260","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1093\/eurheartj\/eht495","article-title":"Long-term survival after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a comparison with general population","volume":"35","author":"Veselka","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0265","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1161\/CIRCINTERVENTIONS.110.959718","article-title":"Long-term outcome of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: a Scandinavian multicenter study","volume":"4","author":"Jensen","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"issue":"1","key":"10.1016\/j.pcad.2023.08.003_bb0270","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.jcin.2008.05.009","article-title":"Long-term outcomes in high risk symptomatic patients with hypertrophic cardiomyopathy undergoing alcohol septal ablation","volume":"2008","author":"Kwon","year":"2008","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.pcad.2023.08.003_bb0275","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.115.003214","article-title":"Influence of septal thickness on the clinical outcome after alcohol septal Alation in hypertrophic cardiomyopathy","volume":"9","author":"Jensen","year":"2016","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.pcad.2023.08.003_bb0280","first-page":"1793","article-title":"Obstruction after alcohol septal ablation is associated with cardiovascular mortality events","volume":"102","author":"Veselka","year":"2016","journal-title":"Heart (British Cardiac Society)"},{"key":"10.1016\/j.pcad.2023.08.003_bb0285","doi-asserted-by":"crossref","first-page":"f198","DOI":"10.1093\/europace\/eux251","article-title":"Validation of the HCM risk-SCD model in patients with hypertrophic cardiomyopathy following alcohol septal ablation","volume":"20","author":"Liebregts","year":"2018","journal-title":"Europace"},{"key":"10.1016\/j.pcad.2023.08.003_bb0290","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.amjcard.2022.08.028","article-title":"Prediction of sudden cardiac arrest after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: ASA-SCARRE risk score","volume":"184","author":"Veselka","year":"2022","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0295","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.jcin.2021.03.066","article-title":"Sex-related differences in outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"14","author":"Veselka","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.pcad.2023.08.003_bb0300","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.jcin.2017.03.030","article-title":"Outcomes of alcohol septal ablation in younger patients with obstructive hypertrophic cardiomyopathy","volume":"10","author":"Liebregts","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.pcad.2023.08.003_bb0305","first-page":"634","article-title":"Survival of patients \u2264 50 years of age after alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"30","author":"Veselka","year":"2014","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0310","first-page":"6","article-title":"Outcome of alcohol septal ablation in mildly symptomatic patients with hypertrophic obstructive cardiomyopathy: a long-term follow-up study based on the euro-alcohol septal ablation registry","author":"Veselka","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.pcad.2023.08.003_bb0315","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jacc.2009.01.079","article-title":"Outcome of mildly symptomatic or asymptomatic obstructive hypertrophic cardiomyopathy: a long-term follow-up study","volume":"54","author":"Sorajja","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0320","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1093\/eurheartj\/ehl041","article-title":"Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy","volume":"27","author":"Elliott","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0325","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.5114\/aoms.2020.97969","article-title":"Long-term outcome of repeated septal reduction therapy after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: insight from the euro-ASA registry","volume":"16","author":"Veselka","year":"2020","journal-title":"Arch Med Sci\u202f: AMS"},{"key":"10.1016\/j.pcad.2023.08.003_bb0330","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1093\/eurheartj\/ehz110","article-title":"Short- and long-term outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy in patients with mild left ventricular hypertrophy: a propensity score matching analysis","volume":"40","author":"Veselka","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0335","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jacc.2005.02.090","article-title":"Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy","volume":"46","author":"Ommen","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0340","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.athoracsur.2007.07.063","article-title":"Current effectiveness and risks of isolated septal myectomy for hypertrophic obstructive cardiomyopathy","volume":"85","author":"Smedira","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0345","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1161\/01.CIR.0000162460.36735.71","article-title":"Clinical and echocardiographic determinants of long-term survival after surgical myectomy in obstructive hypertrophic cardiomyopathy","volume":"111","author":"Woo","year":"2005","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0350","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1016\/j.jacc.2011.08.040","article-title":"Long-term survival in patients with resting obstructive hypertrophic cardiomyopathy comparison of conservative versus invasive treatment","volume":"58","author":"Ball","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0355","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.112.000849","article-title":"Predictors of long term outcomes in symptomatic hypertrophic obstructive cardiomyopathy patients undergoing surgical relief of left ventricular outflow tract obstruction","author":"Desai","year":"2013","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.pcad.2023.08.003_bb0360","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1016\/j.jtcvs.2018.11.148","article-title":"Surgical management of left ventricular outflow tract obstruction in a specialized hypertrophic obstructive cardiomyopathy center","volume":"157","author":"Hodges","year":"2019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0365","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1001\/jamacardio.2016.0252","article-title":"Hospital volume outcomes after septal Myectomy and alcohol septal ablation for treatment of obstructive hypertrophic cardiomyopathy: US Nationwide inpatient database, 2003-2011","volume":"1","author":"Kim","year":"2016","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0370","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.amjcard.2014.07.075","article-title":"Results of ventricular septal myectomy and hypertrophic cardiomyopathy (from Nationwide inpatient sample [1998-2010])","volume":"114","author":"Panaich","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0375","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/clc.23113","article-title":"Alcohol septal ablation vs myectomy for symptomatic hypertrophic obstructive cardiomyopathy: systematic review and meta-analysis","volume":"42","author":"Osman","year":"2019","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0380","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.jacc.2009.09.047","article-title":"Updated meta-analysis of septal alcohol ablation versus myectomy for hypertrophic cardiomyopathy","volume":"55","author":"Agarwal","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0385","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.jacc.2022.02.032","article-title":"Survival following alcohol septal ablation or septal Myectomy for patients with obstructive hypertrophic cardiomyopathy","volume":"79","author":"Cui","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0390","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jacc.2022.10.027","article-title":"Survival after septal reduction in patients >65 years old with obstructive hypertrophic cardiomyopathy","volume":"81","author":"Mentias","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0395","first-page":"16","article-title":"Effect of institutional experience on outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy","volume":"34","author":"Veselka","year":"2018","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0400","first-page":"13","article-title":"Performance volume thresholds for alcohol septal ablation in treating hypertrophic cardiomyopathy: guidelines, competency statements, and now data","volume":"34","author":"Naidu","year":"2018","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0405","first-page":"e558","article-title":"2020 AHA\/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy","volume":"142","author":"Ommen","year":"2020","journal-title":"Circulation."},{"key":"10.1016\/j.pcad.2023.08.003_bb0410","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1093\/eurheartj\/ehu284","article-title":"2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy: the task force for the diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC)","volume":"35","author":"Elliott","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0415","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1093\/eurheartj\/eht537","article-title":"Surgical myectomy improves pulmonary hypertension in obstructive hypertrophic cardiomyopathy","volume":"35","author":"Geske","year":"2014","journal-title":"Eur Heart J"},{"issue":"684\u2013692","key":"10.1016\/j.pcad.2023.08.003_bb0420","article-title":"Predictors of long-term outcomes in patients with hypertrophic cardiomyopathy undergoing cardiopulmonary stress testing and echocardiography","volume":"169","author":"Masri","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.pcad.2023.08.003_bb0425","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.athoracsur.2018.03.039","article-title":"Determinants of reverse remodeling of the left atrium after Transaortic Myectomy","volume":"106","author":"Nguyen","year":"2018","journal-title":"Ann Thorac Surg"},{"issue":"750\u2013759","key":"10.1016\/j.pcad.2023.08.003_bb0430","article-title":"Prediction of sudden death risk in obstructive hypertrophic cardiomyopathy: potential for refinement of current criteria","volume":"156","author":"Desai","year":"2018","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.pcad.2023.08.003_bb0435","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jacc.2022.04.048","article-title":"Myosin inhibition in patients with obstructive hypertrophic cardiomyopathy referred for septal reduction therapy","volume":"80","author":"Desai","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0440","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1016\/S0140-6736(21)00763-7","article-title":"Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): health status analysis of a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"397","author":"Spertus","year":"2021","journal-title":"The Lancet"},{"issue":"11","key":"10.1016\/j.pcad.2023.08.003_bb0445","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1161\/CIRCULATIONAHA.122.062534","article-title":"Dose-blinded myosin inhibition in patients with obstructive HCM referred for septal reduction therapy: outcomes through 32-weeks","volume":"147","author":"Desai","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.pcad.2023.08.003_bb0450","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0140-6736(20)31792-X","article-title":"Jacoby D and investigators E-Hs. Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"396","author":"Olivotto","year":"2020","journal-title":"Lancet."},{"key":"10.1016\/j.pcad.2023.08.003_bb0455","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1016\/j.jacc.2018.07.080","article-title":"Percutaneous Intramyocardial septal radiofrequency ablation for hypertrophic obstructive cardiomyopathy","volume":"72","author":"Liu","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0460","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/clc.23341","article-title":"Efficacy and safety of radiofrequency ablation for hypertrophic obstructive cardiomyopathy: a systematic review and meta-analysis","volume":"43","author":"Yang","year":"2020","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0465","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.743044","article-title":"Selective interventricular septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy: who can benefit?","volume":"8","author":"Liu","year":"2021","journal-title":"Front Cardiovas Med"},{"key":"10.1016\/j.pcad.2023.08.003_bb0470","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1016\/j.jacc.2016.03.587","article-title":"First experience with percutaneous mitral valve plication as primary therapy for symptomatic obstructive hypertrophic cardiomyopathy","volume":"67","author":"Sorajja","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0475","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1016\/S0735-1097(21)03282-4","article-title":"Mitraclip for the treatment of symptomatic left ventricular outflow tract obstruction due to systolic anterior motion of the anterior leaflet after surgical mitral valve repair","volume":"77","author":"Aziz","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.pcad.2023.08.003_bb0480","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0735-1097(22)01854-X","article-title":"Percutaneous mitral valve repair for hypertrophic obstructive cardiomyopathy","volume":"79","author":"Modi","year":"2022","journal-title":"J Am Coll Cardiol"}],"container-title":["Progress in Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033062023000786?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033062023000786?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:21:54Z","timestamp":1758500514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0033062023000786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":96,"alternative-id":["S0033062023000786"],"URL":"https:\/\/doi.org\/10.1016\/j.pcad.2023.08.003","relation":{},"ISSN":["0033-0620"],"issn-type":[{"value":"0033-0620","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Invasive therapies for symptomatic obstructive hypertrophic cardiomyopathy","name":"articletitle","label":"Article Title"},{"value":"Progress in Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pcad.2023.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}