{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T09:22:26Z","timestamp":1781169746095,"version":"3.54.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","primary-care-diabetes.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Primary Care Diabetes"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.pcd.2016.04.001","type":"journal-article","created":{"date-parts":[[2016,5,12]],"date-time":"2016-05-12T17:31:49Z","timestamp":1463074309000},"page":"434-441","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Retrospective study of the evolution of the incidence of non-traumatic lower-extremity amputations (2007\u20132013) and risk factors of reamputation"],"prefix":"10.1016","volume":"10","author":[{"given":"Isabel","family":"Font-Jim\u00e9nez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireia","family":"Llaurado-Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Roig-Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belen","family":"De los Mozos-Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagrario","family":"Acebedo-Urdiales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.pcd.2016.04.001_bib0220","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2337\/dc07-1159","article-title":"Diabetes- and nondiabetes-related lower extremity amputation incidence before and after the introduction of better organized diabetes foot care: continuous longitudinal monitoring using a standard method","volume":"31","author":"Canavan","year":"2008","journal-title":"Diabetes Care"},{"issue":"8","key":"10.1016\/j.pcd.2016.04.001_bib0225","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1111\/j.1464-5491.2009.02770.x","article-title":"Decreasing amputation rates in patients with diabetes\u2014a population-based study","volume":"26","author":"Schofield","year":"2009","journal-title":"Diabet Med."},{"issue":"3","key":"10.1016\/j.pcd.2016.04.001_bib0230","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.diabres.2011.10.035","article-title":"Incidence of lower limb amputations in individuals with and without diabetes mellitus in Andalusia (Spain) from 1998 to 2006","volume":"95","author":"Almaraz","year":"2012","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.pcd.2016.04.001_bib0235","unstructured":"Internacional DF, ATLAS de la DIABETES de la FID, 2015, https:\/\/www.idf.org\/sites\/default\/files\/SP_6E_Atlas_Full.pdf (consulted November 8th 2015)."},{"issue":"Supl. 1","key":"10.1016\/j.pcd.2016.04.001_bib0240","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1157\/13086022","article-title":"La diabetes mellitus en Espa\u00f1a: mortalidad, prevalencia, incidencia, costes econ\u00f3micos y desigualdades","volume":"20","author":"Ruiz-Ramos","year":"2006","journal-title":"Gac. Sanit."},{"key":"10.1016\/j.pcd.2016.04.001_bib0245","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s00125-011-2336-9","article-title":"Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study","volume":"55","author":"Soriguer","year":"2012","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.pcd.2016.04.001_bib0250","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1001\/jama.293.2.217","article-title":"Preventing foot ulcers in patients with diabetes","volume":"293","author":"Singh","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.pcd.2016.04.001_bib0255","unstructured":"OECD Indicators OP, Health at a Glance 2009 OECD INDICATORS, 2009. Available from: http:\/\/www.oecd.org\/health\/health-systems\/44117530.pdf (consulted October 10th 2015) (Internet)."},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0260","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.atherosclerosis.2008.03.002","article-title":"PROactive investigators. Impact of peripheral arterial disease in patients with diabetes-results from PROactive (PROactive 11)","volume":"202","author":"Dormandy","year":"2009","journal-title":"Atherosclerosis"},{"issue":"3","key":"10.1016\/j.pcd.2016.04.001_bib0265","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ejvs.2009.04.013","article-title":"Prevalence of symptomatic and asymptomatic peripheral arterial disease and the value of the ankle-brachial index to stratify cardiovascular risk","volume":"38","author":"Ramos","year":"2009","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"issue":"S","key":"10.1016\/j.pcd.2016.04.001_bib0270","first-page":"S1","article-title":"Inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J. Vasc. Surg."},{"issue":"3","key":"10.1016\/j.pcd.2016.04.001_bib0275","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.aprim.2015.04.009","article-title":"Factores psicosociales implicados en la amputaci\u00f3n. Revisi\u00f3n sistem\u00e1tica de la literatura","volume":"48","author":"Font-Jimenez","year":"2016","journal-title":"Atenci\u00f3n Primaria"},{"issue":"10","key":"10.1016\/j.pcd.2016.04.001_bib0280","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/j.1464-5491.2009.02802.x","article-title":"Psychosocial adjustment to diabetes-related lower limb amputation","volume":"26","author":"Coffey","year":"2009","journal-title":"Diabet. Med."},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0285","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/1472-6963-12-213","article-title":"Group based diabetes self-management education compared to routine treatment for people with type 2 diabetes mellitus. A systematic review with meta-analysis","volume":"12","author":"Steinsbekk","year":"2012","journal-title":"BMC Health Serv. Res."},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0290","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2337\/dc07-1178","article-title":"Reduction of diabetic amputations over 11 years of UK population defined: Benefits of multidisciplinary teamwork and continuous prospective audit","volume":"31","author":"Krishnan","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.pcd.2016.04.001_bib0295","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.2337\/diacare.27.5.1042","article-title":"Reduction in diabetes-related lower-extremity amputations in The Netherlands: 1991\u20132000","volume":"27","author":"van Houtum","year":"2004","journal-title":"Diabetes Care"},{"issue":"12","key":"10.1016\/j.pcd.2016.04.001_bib0300","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1007\/s00125-004-1584-3","article-title":"Amputation as a marker of the quality of foot care in diabetes","volume":"47","author":"Jeffcoate","year":"2004","journal-title":"Diabetologia"},{"issue":"7","key":"10.1016\/j.pcd.2016.04.001_bib0305","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.2337\/dc11-0077","article-title":"Trends in lower-extremity amputations in people with and without diabetes in Spain, 2001\u20132008","volume":"34","author":"Lopez-de-Andres","year":"2011","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0310","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/1534734614521234","article-title":"Reducing major lower extremity amputations after the introduction of a multidisciplinary team for the diabetic foot","volume":"13","author":"Rubio","year":"2014","journal-title":"Int. J. Low Extrem. Wounds"},{"key":"10.1016\/j.pcd.2016.04.001_bib0315","unstructured":"Ministerio de Sanidad SS e I, Indicadores Clave. Sistema Nacional de Salud, 2011. Available from: http:\/\/inclasns.msssi.es\/main.html (consulted November 8th 2015) (Internet)."},{"key":"10.1016\/j.pcd.2016.04.001_bib0320","unstructured":"Ministerio de Sanidad Servicios Sociales e Igualdad GDE, CIE 9 MC. Clasificaci\u00f3n Internacional de Enfermedades, 2014, pp. 1149\u20131150. Available from: https:\/\/eciemaps.mspsi.es\/ecieMaps\/browser\/index_9_mc.html (Consulted: October 25th 2015) (Internet)."},{"key":"10.1016\/j.pcd.2016.04.001_bib0325","unstructured":"Catalunya I d\u2019Estadistica de. Poblaci\u00f3. Provincies, 2015, Available from: http:\/\/www.idescat.cat\/pub\/?id=aec&n=245 (consulted December 1st 2015)."},{"issue":"12","key":"10.1016\/j.pcd.2016.04.001_bib0330","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.2337\/dc12-0511","article-title":"Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: a nationwide study","volume":"35","author":"Kennon","year":"2012","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1016\/j.pcd.2016.04.001_bib0335","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1742-481X.2007.00313.x","article-title":"Re-amputation occurrence in the diabetic population in South Wales, UK","volume":"4","author":"Kanade","year":"2007","journal-title":"Int. Wound J."},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0340","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0086405","article-title":"Lower extremity amputations in persons with and without diabetes in Italy: 2001\u20132010","volume":"9","author":"Lombardo","year":"2014","journal-title":"PLoS ONE"},{"issue":"9","key":"10.1016\/j.pcd.2016.04.001_bib0345","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2337\/diacare.24.9.1686","article-title":"Epidemiology of nontraumatic Lower-Extremity Amputation in Area 7, Madrid, between 1989 and 1999","volume":"24","author":"Calle-Pascual","year":"2001","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0350","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ejvs.2005.12.025","article-title":"The national hospital discharge register data on lower limb amputations","volume":"32","author":"Winell","year":"2006","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"issue":"7","key":"10.1016\/j.pcd.2016.04.001_bib0355","doi-asserted-by":"crossref","first-page":"e41492","DOI":"10.1371\/journal.pone.0041492","article-title":"Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland","volume":"7","author":"Buckley","year":"2012","journal-title":"PLoS ONE"},{"issue":"2","key":"10.1016\/j.pcd.2016.04.001_bib0365","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.diabres.2009.11.016","article-title":"Trends in lower extremity amputations in people with and without diabetes in England, 1996\u20132005","volume":"87","author":"Vamos","year":"2010","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"4","key":"10.1016\/j.pcd.2016.04.001_bib0370","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jdiacomp.2011.02.001","article-title":"The importance of limb preservation in the diabetic population","volume":"25","author":"Evans","year":"2011","journal-title":"J. Diabetes Complications"},{"issue":"6","key":"10.1016\/j.pcd.2016.04.001_bib0375","doi-asserted-by":"crossref","first-page":"264","DOI":"10.12968\/jowc.2011.20.6.261","article-title":"Minor amputation in patients with diabetes mellitus and severe foot ulcers achieves good outcomes","volume":"20","author":"Svensson","year":"2011","journal-title":"J. Wound Care"},{"issue":"3","key":"10.1016\/j.pcd.2016.04.001_bib0380","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1177\/1534734614543663","article-title":"Minor amputation and palliative wound care as a strategy to avoid major amputation in patients with foot infections and severe peripheral arterial disease","volume":"13","author":"Barshes","year":"2014","journal-title":"Int. J. Low Extrem. Wounds"},{"issue":"4","key":"10.1016\/j.pcd.2016.04.001_bib0385","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1464-5491.2009.02698.x","article-title":"Incidence and characteristics of lower limb amputations in people with diabetes","volume":"26","author":"Fosse","year":"2009","journal-title":"Diabet Med."},{"issue":"1","key":"10.1016\/j.pcd.2016.04.001_bib0390","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0741-5214(03)00092-2","article-title":"Functional outcome in a contemporary series of major lower extremity amputation","volume":"38","author":"Nehler","year":"2003","journal-title":"J. Vasc. Surg."},{"issue":"6","key":"10.1016\/j.pcd.2016.04.001_bib0395","first-page":"127","article-title":"The influence of gender as a risk factor in diabetic foot ulceration","volume":"20","author":"Dinh","year":"2008","journal-title":"Wounds"},{"key":"10.1016\/j.pcd.2016.04.001_bib0400","doi-asserted-by":"crossref","unstructured":"J.A. Rubio, C. Salido, A. Albarrac\u00edn, S. Jim\u00e9nez, J. \u00c1lvarez, Incidencia de amputaciones de extremidades inferiores en el \u00e1rea 3 de Madrid. Estudio retrospectivo del periodo 2001\u20132006, Rev. Cl\u00ednica Espa\u00f1ola 210 (2) (2010) 65\u201369.","DOI":"10.1016\/j.rce.2009.06.010"},{"issue":"2","key":"10.1016\/j.pcd.2016.04.001_bib0405","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jvs.2012.01.041","article-title":"Prior contralateral amputation predicts worse outcomes for lower extremity baypasses performed in the intact limb","volume":"56","author":"Baril","year":"2012","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.pcd.2016.04.001_bib0410","doi-asserted-by":"crossref","unstructured":"J. Apelqvist, J. Larsson, What is the most effective way to reduce incidence of amputation in the diabetic foot? Diabetes Metab. Res. Rev. 16 (Suppl. 1) (2000) S75\u2013S83.","DOI":"10.1002\/1520-7560(200009\/10)16:1+<::AID-DMRR139>3.3.CO;2-#"},{"key":"10.1016\/j.pcd.2016.04.001_bib0415","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3402\/dfa.v3i0.12169","article-title":"Incidence of re-amputation following partial first ray amputation associated with diabetes mellitus and peripheral sensory neuropathy: a systematic review","volume":"3","author":"Borkosky","year":"2012","journal-title":"Diabet. Foot Ankle"},{"key":"10.1016\/j.pcd.2016.04.001_bib0420","doi-asserted-by":"crossref","first-page":"566","DOI":"10.2337\/diacare.29.03.06.dc05-1992","article-title":"Risk of reamputation in diabetic patients","volume":"29","author":"Izumi","year":"2006","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.pcd.2016.04.001_bib0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2013.06.055","article-title":"Fate of the contralateral limb after lower extremity amputation","volume":"58","author":"Glaser","year":"2013","journal-title":"J. Vasc. Surg."},{"issue":"5","key":"10.1016\/j.pcd.2016.04.001_bib0430","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.mcna.2013.03.008","article-title":"Epidemiology of foot ulceration and amputation: can global variation be explained?","volume":"97","author":"Margolis","year":"2013","journal-title":"Med. Clin. North Am."}],"container-title":["Primary Care Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751991816300201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1751991816300201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T23:55:35Z","timestamp":1761695735000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1751991816300201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S1751991816300201"],"URL":"https:\/\/doi.org\/10.1016\/j.pcd.2016.04.001","relation":{},"ISSN":["1751-9918"],"issn-type":[{"value":"1751-9918","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Retrospective study of the evolution of the incidence of non-traumatic lower-extremity amputations (2007\u20132013) and risk factors of reamputation","name":"articletitle","label":"Article Title"},{"value":"Primary Care Diabetes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pcd.2016.04.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}