{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T03:36:41Z","timestamp":1768880201421,"version":"3.49.0"},"reference-count":76,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","pediatric.theclinics.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Clinics of North America"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.pcl.2015.04.006","type":"journal-article","created":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T00:32:34Z","timestamp":1431477154000},"page":"841-855","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Child with Multiple Fractures, What Next?"],"prefix":"10.1016","volume":"62","author":[{"given":"Jennifer","family":"Harrington","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Sochett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.injury.2011.11.006","article-title":"The increasing incidence of paediatric diaphyseal both-bone forearm fractures and their internal fixation during the last decade","volume":"43","author":"Sinikumpu","year":"2012","journal-title":"Injury"},{"issue":"11","key":"10.1016\/j.pcl.2015.04.006_bib2","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1001\/jama.290.11.1479","article-title":"Incidence of childhood distal forearm fractures over 30 years: a population-based study","volume":"290","author":"Khosla","year":"2003","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3109\/17453671003628780","article-title":"Epidemiology of fractures in children and adolescents","volume":"81","author":"Hedstrom","year":"2010","journal-title":"Acta Orthop"},{"issue":"12","key":"10.1016\/j.pcl.2015.04.006_bib4","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1359\/jbmr.040902","article-title":"Epidemiology of childhood fractures in Britain: a study using the general practice research database","volume":"19","author":"Cooper","year":"2004","journal-title":"J\u00a0Bone Miner Res"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s00198-008-0627-x","article-title":"Fracture rates in urban South African children of different ethnic origins: the Birth to Twenty cohort","volume":"20","author":"Thandrayen","year":"2009","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.pcl.2015.04.006_bib6","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1186\/1471-2458-10-656","article-title":"Pattern of fractures across pediatric age groups: analysis of individual and lifestyle factors","volume":"10","author":"Valerio","year":"2010","journal-title":"BMC Public Health"},{"issue":"12","key":"10.1016\/j.pcl.2015.04.006_bib7","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1007\/s001980200137","article-title":"How many children remain fracture-free during growth? a longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study","volume":"13","author":"Jones","year":"2002","journal-title":"Osteoporos Int"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib8","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/jbmr.1579","article-title":"Impaired bone health and asymptomatic vertebral compressions in fracture-prone children: a case-control study","volume":"27","author":"Mayranpaa","year":"2012","journal-title":"J\u00a0Bone Miner Res"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib9","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1007\/s00198-014-2655-z","article-title":"The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group","volume":"25","author":"Siris","year":"2014","journal-title":"Osteoporos Int"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib10","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jocd.2014.01.004","article-title":"Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 Pediatric Official Positions","volume":"17","author":"Bishop","year":"2014","journal-title":"J\u00a0Clin Densitom"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib11","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1359\/jbmr.081255","article-title":"Bone structure at the distal radius during adolescent growth","volume":"24","author":"Kirmani","year":"2009","journal-title":"J\u00a0Bone Miner Res"},{"issue":"7","key":"10.1016\/j.pcl.2015.04.006_bib12","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1002\/jbmr.46","article-title":"Rapid growth produces transient cortical weakness: a risk factor for metaphyseal fractures during puberty","volume":"25","author":"Wang","year":"2010","journal-title":"J\u00a0Bone Miner Res"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib13","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/BF02652557","article-title":"Asynchrony between the rates of standing height gain and bone mass accumulation during puberty","volume":"7","author":"Fournier","year":"1997","journal-title":"Osteoporos Int"},{"issue":"12","key":"10.1016\/j.pcl.2015.04.006_bib14","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1359\/jbmr.060907","article-title":"Size-corrected BMD decreases during peak linear growth: implications for fracture incidence during adolescence","volume":"21","author":"Faulkner","year":"2006","journal-title":"J\u00a0Bone Miner Res"},{"issue":"10","key":"10.1016\/j.pcl.2015.04.006_bib15","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1359\/jbmr.1999.14.10.1672","article-title":"A\u00a0six-year longitudinal study of the relationship of physical activity to bone mineral accrual in growing children: the University of Saskatchewan bone mineral accrual study","volume":"14","author":"Bailey","year":"1999","journal-title":"J\u00a0Bone Miner Res"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/01202412-199704000-00002","article-title":"Epidemiology of children's fractures","volume":"6","author":"Landin","year":"1997","journal-title":"J\u00a0Pediatr Orthop B"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib17","first-page":"337","article-title":"Trauma to the thoracic and lumbar spine in the adolescent","volume":"44","author":"Clark","year":"2001","journal-title":"Can J Surg"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib18","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/ajmg.c.30073","article-title":"A\u00a0genetic approach to fracture epidemiology in childhood","volume":"139C","author":"Tinkle","year":"2005","journal-title":"Am J Med Genet C Semin Med Genet"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib19","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/jbmr.2071","article-title":"Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma","volume":"29","author":"Farr","year":"2014","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.pcl.2015.04.006_bib20","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/jbmr.2257","article-title":"Diminished bone strength is observed in adult women and men who sustained a mild trauma distal forearm fracture during childhood","volume":"29","author":"Farr","year":"2014","journal-title":"J\u00a0Bone Miner Res"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib21","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S8756-3282(03)00220-5","article-title":"Bone response to jumping is site-specific in children: a randomized trial","volume":"33","author":"Johannsen","year":"2003","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00223-008-9166-x","article-title":"A\u00a03-year physical activity intervention program increases the gain in bone mineral and bone width in prepubertal girls but not boys: the prospective copenhagen school child interventions study (CoSCIS)","volume":"83","author":"Hasselstrom","year":"2008","journal-title":"Calcif Tissue Int"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib23","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s007760100024","article-title":"The epidemiology of elbow fracture in children: analysis of 355 fractures, with special reference to supracondylar humerus fractures","volume":"6","author":"Houshian","year":"2001","journal-title":"J\u00a0Orthop Sci"},{"issue":"7","key":"10.1016\/j.pcl.2015.04.006_bib24","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1359\/jbmr.080303","article-title":"Vigorous physical activity increases fracture risk in children irrespective of bone mass: a prospective study of the independent risk factors for fractures in healthy children","volume":"23","author":"Clark","year":"2008","journal-title":"J\u00a0Bone Miner Res"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib25","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1007\/s00198-011-1713-z","article-title":"Interpretation and use of FRAX in clinical practice","volume":"22","author":"Kanis","year":"2011","journal-title":"Osteoporos Int"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib26","doi-asserted-by":"crossref","first-page":"e291","DOI":"10.1542\/peds.2005-1404","article-title":"Association between bone density and fractures in children: a systematic review and meta-analysis","volume":"117","author":"Clark","year":"2006","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib27","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1359\/jbmr.060601","article-title":"Association between bone mass and fractures in children: a prospective cohort study","volume":"21","author":"Clark","year":"2006","journal-title":"J\u00a0Bone Miner Res"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1210\/edrv.23.3.0464","article-title":"Genetics of osteoporosis","volume":"23","author":"Peacock","year":"2002","journal-title":"Endocr Rev"},{"issue":"10","key":"10.1016\/j.pcl.2015.04.006_bib29","doi-asserted-by":"crossref","first-page":"E1958","DOI":"10.1210\/jc.2012-1890","article-title":"Clinical review: genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed","volume":"97","author":"Hsu","year":"2012","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2015.04.006_bib30","doi-asserted-by":"crossref","first-page":"e1004423","DOI":"10.1371\/journal.pgen.1004423","article-title":"Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment","volume":"10","author":"Kemp","year":"2014","journal-title":"PLoS Genet"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib31","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1359\/jbmr.2000.15.1.13","article-title":"Trabecular bone microarchitecture, bone mineral density, and vertebral fractures in male osteoporosis","volume":"15","author":"Legrand","year":"2000","journal-title":"J\u00a0Bone Miner Res"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib32","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/MOP.0000000000000117","article-title":"Osteogenesis imperfecta due to mutations in non-collagenous genes: lessons in the biology of bone formation","volume":"26","author":"Marini","year":"2014","journal-title":"Curr Opin Pediatr"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib33","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1002\/jbmr.1942","article-title":"Skeletal clinical characteristics of osteogenesis imperfecta caused by haploinsufficiency mutations in COL1A1","volume":"28","author":"Ben Amor","year":"2013","journal-title":"J\u00a0Bone Miner Res"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib34","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0929-6646(09)60187-X","article-title":"Clinical features of Ehlers-Danlos syndrome","volume":"105","author":"Yen","year":"2006","journal-title":"J\u00a0Formos Med Assoc"},{"issue":"10","key":"10.1016\/j.pcl.2015.04.006_bib35","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1136\/ard.57.10.630","article-title":"Assessment of bone in Ehlers Danlos syndrome by ultrasound and densitometry","volume":"57","author":"Dolan","year":"1998","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib36","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1359\/jbmr.2000.15.5.957","article-title":"Deficient bone formation in idiopathic juvenile osteoporosis: a histomorphometric study of cancellous iliac bone","volume":"15","author":"Rauch","year":"2000","journal-title":"J\u00a0Bone Miner Res"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib37","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/rheumatology\/34.1.68","article-title":"Idiopathic juvenile osteoporosis: experience of twenty-one patients","volume":"34","author":"Smith","year":"1995","journal-title":"Br J\u00a0Rheumatol"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib38","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00223-001-0045-y","article-title":"Idiopathic juvenile osteoporosis","volume":"70","author":"Lorenc","year":"2002","journal-title":"Calcif Tissue Int"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib39","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1359\/jbmr.2003.18.5.913","article-title":"Children and the risk of fractures caused by oral corticosteroids","volume":"18","author":"van Staa","year":"2003","journal-title":"J\u00a0Bone Miner Res"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib40","first-page":"729","article-title":"Bone mineral density in children and adolescents with systemic lupus erythematosus, juvenile dermatomyositis, and systemic vasculitis: relationship to disease duration, cumulative corticosteroid dose, calcium intake, and exercise","volume":"32","author":"Alsufyani","year":"2005","journal-title":"J\u00a0Rheumatol"},{"issue":"5","key":"10.1016\/j.pcl.2015.04.006_bib41","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1359\/jbmr.070121","article-title":"Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation through NF-kappaB","volume":"22","author":"Li","year":"2007","journal-title":"J\u00a0Bone Miner Res"},{"issue":"12","key":"10.1016\/j.pcl.2015.04.006_bib42","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1007\/s00198-008-0624-0","article-title":"Bone in celiac disease","volume":"19","author":"Bianchi","year":"2008","journal-title":"Osteoporos Int"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib43","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/01202412-200001000-00013","article-title":"Vertebral collapse and normal peripheral blood cell count at the onset of acute lymphatic leukemia in childhood","volume":"9","author":"Kayser","year":"2000","journal-title":"J\u00a0Pediatr Orthop B"},{"issue":"7","key":"10.1016\/j.pcl.2015.04.006_bib44","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1359\/jbmr.090202","article-title":"Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program","volume":"24","author":"Halton","year":"2009","journal-title":"J\u00a0Bone Miner Res"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib45","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/acr.20171","article-title":"Prevalent vertebral fractures among children initiating glucocorticoid therapy for the treatment of rheumatic disorders","volume":"62","author":"Huber","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib46","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1177\/0883073812443005","article-title":"Antiepileptic drugs and bone metabolism in children: data from 128 patients","volume":"28","author":"Borusiak","year":"2013","journal-title":"J\u00a0Child Neurol"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib47","doi-asserted-by":"crossref","first-page":"54","DOI":"10.5527\/wjn.v1.i2.54","article-title":"Bone disease in pediatric idiopathic hypercalciuria","volume":"1","author":"Moreira Guimaraes Penido","year":"2012","journal-title":"World J Nephrol"},{"issue":"8","key":"10.1016\/j.pcl.2015.04.006_bib48","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1002\/jbmr.373","article-title":"Bone biopsy findings and correlation with clinical, radiological, and biochemical parameters in children with fractures","volume":"26","author":"Mayranpaa","year":"2011","journal-title":"J\u00a0Bone Miner Res"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib49","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.2007-1894","article-title":"Vitamin D deficiency in children and its management: review of current knowledge and recommendations","volume":"122","author":"Misra","year":"2008","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib50","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3899\/jrheum.110305","article-title":"Prevalence of vertebral compression fractures and associated factors in children and adolescents with severe juvenile idiopathic arthritis","volume":"39","author":"Markula-Patjas","year":"2012","journal-title":"J\u00a0Rheumatol"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib51","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","article-title":"Vertebral fracture assessment using a semiquantitative technique","volume":"8","author":"Genant","year":"1993","journal-title":"J\u00a0Bone Miner Res"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib52","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1359\/JBMR.051107","article-title":"Incidence and predictors of fractures in children after solid organ transplantation: a 5-year prospective, population-based study","volume":"21","author":"Helenius","year":"2006","journal-title":"J\u00a0Bone Miner Res"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib53","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jocd.2014.01.003","article-title":"Dual-energy X-ray absorptiometry interpretation and reporting in children and adolescents: the revised 2013 ISCD Pediatric Official Positions","volume":"17","author":"Crabtree","year":"2014","journal-title":"J\u00a0Clin Densitom"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib54","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.bone.2007.07.008","article-title":"Osteoporosis in children and adolescents","volume":"41","author":"Bianchi","year":"2007","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib55","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.jpeds.2005.01.028","article-title":"Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CT","volume":"146","author":"Wren","year":"2005","journal-title":"J\u00a0Pediatr"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib56","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1210\/jc.2009-2057","article-title":"Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children","volume":"95","author":"Zemel","year":"2010","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2015.04.006_bib57","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1002\/jbmr.2254","article-title":"Influence of physical activity on bone strength in children and adolescents: a systematic review and narrative synthesis","volume":"29","author":"Tan","year":"2014","journal-title":"J\u00a0Bone Miner Res"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib58","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/jbmr.2168","article-title":"A\u00a06-year exercise program improves skeletal traits without affecting fracture risk: a prospective controlled study in 2621 children","volume":"29","author":"Detter","year":"2014","journal-title":"J\u00a0Bone Miner Res"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib59","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1359\/jbmr.061205","article-title":"Is a school-based physical activity intervention effective for increasing tibial bone strength in boys and girls?","volume":"22","author":"Macdonald","year":"2007","journal-title":"J\u00a0Bone Miner Res"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib60","first-page":"151","article-title":"Effect of a new physiotherapy concept on bone mineral density, muscle force and gross motor function in children with bilateral cerebral palsy","volume":"10","author":"Stark","year":"2010","journal-title":"J\u00a0Musculoskelet Neuronal Interact"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib61","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1080\/14763141.2011.629208","article-title":"Whole-body vibration effects on the muscle activity of upper and lower body muscles during the baseball swing in recreational baseball hitters","volume":"10","author":"Reyes","year":"2011","journal-title":"Sports Biomech"},{"issue":"1","key":"10.1016\/j.pcl.2015.04.006_bib62","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1210\/jc.2010-2704","article-title":"The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know","volume":"96","author":"Ross","year":"2011","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib63","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/ajcn\/71.2.544","article-title":"Effect of calcium supplementation on bone mineral accretion in gambian children accustomed to a low-calcium diet","volume":"71","author":"Dibba","year":"2000","journal-title":"Am J\u00a0Clin Nutr"},{"issue":"7572","key":"10.1016\/j.pcl.2015.04.006_bib64","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1136\/bmj.38950.561400.55","article-title":"Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials","volume":"333","author":"Winzenberg","year":"2006","journal-title":"BMJ"},{"issue":"7638","key":"10.1016\/j.pcl.2015.04.006_bib65","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bmj.39440.525752.BE","article-title":"Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial","volume":"336","author":"Bolland","year":"2008","journal-title":"BMJ"},{"issue":"Suppl 2","key":"10.1016\/j.pcl.2015.04.006_bib66","doi-asserted-by":"crossref","first-page":"S150","DOI":"10.1542\/peds.2006-2023H","article-title":"Bisphosphonates: mode of action and pharmacology","volume":"119","author":"Russell","year":"2007","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib67","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1172\/JCI0215952","article-title":"The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta","volume":"110","author":"Rauch","year":"2002","journal-title":"J\u00a0Clin Invest"},{"issue":"3","key":"10.1016\/j.pcl.2015.04.006_bib68","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.bone.2007.05.002","article-title":"Acute phase response and mineral status following low dose intravenous zoledronic acid in children","volume":"41","author":"Munns","year":"2007","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib69","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/S1470-2045(06)70726-4","article-title":"Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment","volume":"7","author":"Migliorati","year":"2006","journal-title":"Lancet Oncol"},{"issue":"14","key":"10.1016\/j.pcl.2015.04.006_bib70","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1056\/NEJM199810013391402","article-title":"Cyclic administration of pamidronate in children with severe osteogenesis imperfecta","volume":"339","author":"Glorieux","year":"1998","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.pcl.2015.04.006_bib71","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.bone.2006.04.004","article-title":"Vertebral morphometry in children and adolescents with osteogenesis imperfecta: effect of intravenous pamidronate treatment","volume":"39","author":"Land","year":"2006","journal-title":"Bone"},{"issue":"8","key":"10.1016\/j.pcl.2015.04.006_bib72","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1111\/j.1651-2227.2007.00390.x","article-title":"Effect of intravenous pamidronate therapy on everyday activities in children with osteogenesis imperfecta","volume":"96","author":"Lowing","year":"2007","journal-title":"Acta Paediatr"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib73","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1210\/jc.2010-0636","article-title":"Alendronate for the treatment of pediatric osteogenesis imperfecta: a randomized placebo-controlled study","volume":"96","author":"Ward","year":"2011","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.pcl.2015.04.006_bib74","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1359\/JBMR.050109","article-title":"Controlled trial of pamidronate in children with types III and IV osteogenesis imperfecta confirms vertebral gains but not short-term functional improvement","volume":"20","author":"Letocha","year":"2005","journal-title":"J\u00a0Bone Miner Res"},{"issue":"2","key":"10.1016\/j.pcl.2015.04.006_bib75","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1469-8749.2011.04091.x","article-title":"Informing evidence-based clinical practice guidelines for children with cerebral palsy at risk of osteoporosis: a systematic review","volume":"54","author":"Fehlings","year":"2012","journal-title":"Dev Med Child Neurol"},{"issue":"9","key":"10.1016\/j.pcl.2015.04.006_bib76","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/adc.2006.093997","article-title":"Systematic review of effectiveness of bisphosphonates in treatment of low bone mineral density and fragility fractures in juvenile idiopathic arthritis","volume":"91","author":"Thornton","year":"2006","journal-title":"Arch Dis Child"}],"container-title":["Pediatric Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031395515000462?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031395515000462?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,24]],"date-time":"2019-08-24T20:56:01Z","timestamp":1566680161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031395515000462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":76,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0031395515000462"],"URL":"https:\/\/doi.org\/10.1016\/j.pcl.2015.04.006","relation":{},"ISSN":["0031-3955"],"issn-type":[{"value":"0031-3955","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Child with Multiple Fractures, What Next?","name":"articletitle","label":"Article Title"},{"value":"Pediatric Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pcl.2015.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown copyright \u00a9 2015 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}