{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:58:29Z","timestamp":1781661509474,"version":"3.54.5"},"reference-count":93,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T00:00:00Z","timestamp":1596844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003122","name":"Ferring","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003122","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Clinics of North America"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.pcl.2020.08.002","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T16:10:22Z","timestamp":1604074222000},"page":"1171-1186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Endocrine Health in Childhood Cancer Survivors"],"prefix":"10.1016","volume":"67","author":[{"given":"Hanneke M.","family":"van Santen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wassim","family":"Chemaitilly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian R.","family":"Meacham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Tonorezos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sogol","family":"Mostoufi-Moab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pcl.2020.08.002_bib1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000493943","article-title":"Childhood cancer treatments and associated endocrine late effects: a concise guide for the pediatric endocrinologist","volume":"91","author":"Chemaitilly","year":"2019","journal-title":"Horm Res Paediatr"},{"issue":"12","key":"10.1016\/j.pcl.2020.08.002_bib2","doi-asserted-by":"crossref","first-page":"6101","DOI":"10.1210\/jc.2019-00834","article-title":"Hypothalamic-pituitary disorders in childhood cancer survivors: prevalence, risk factors and long-term health outcomes","volume":"104","author":"van Iersel","year":"2019","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib3","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1200\/JCO.2014.56.7933","article-title":"Anterior hypopituitarism in adult survivors of childhood cancers treated with cranial radiotherapy: a report from the St Jude Lifetime Cohort Study","volume":"33","author":"Chemaitilly","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fped.2014.00101","article-title":"Endocrinopathies in survivors of childhood neoplasia","volume":"2","author":"Barnes","year":"2014","journal-title":"Front Pediatr"},{"key":"10.1016\/j.pcl.2020.08.002_bib5","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1210\/jc.2015-2028","article-title":"Neuroendocrine morbidity after pediatric optic gliomas: a longitudinal analysis of 166 children over 30 years","volume":"100","author":"Gan","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib6","doi-asserted-by":"crossref","first-page":"4362","DOI":"10.1200\/JCO.2016.67.5025","article-title":"Prevalence and risk factors of early endocrine disorders in childhood brain tumor survivors: a nationwide, multicenter study","volume":"34","author":"Clement","year":"2016","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1046\/j.1365-2265.2000.01079.x","article-title":"Cranial radiotherapy of childhood brain tumours: growth hormone deficiency and its relation to the biological effective dose of irradiation in a large population based study","volume":"53","author":"Schmiegelow","year":"2000","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.pcl.2020.08.002_bib8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1365-2265.1976.tb01955.x","article-title":"The effect of varying doses of cerebral irradiation on growth hormone production in childhood","volume":"5","author":"Shalet","year":"1976","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.pcl.2020.08.002_bib9","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/1097-0142(197602)37:2+<1144::AID-CNCR2820370824>3.0.CO;2-U","article-title":"Growth hormone deficiency in children with brain tumors","volume":"37","author":"Shalet","year":"1976","journal-title":"Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib10","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/S0360-3016(01)02788-2","article-title":"Radiation dose-volume effects on growth hormone secretion","volume":"52","author":"Merchant","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.pcl.2020.08.002_bib11","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11102-006-6042-4","article-title":"Hypopituitarism as a consequence of brain tumours and radiotherapy","volume":"8","author":"Darzy","year":"2005","journal-title":"Pituitary"},{"key":"10.1016\/j.pcl.2020.08.002_bib12","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1046\/j.1365-2141.2002.03527.x","article-title":"Endocrine late effects after bone marrow transplant","volume":"118","author":"Brennan","year":"2002","journal-title":"Br J Haematol"},{"key":"10.1016\/j.pcl.2020.08.002_bib13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/pbc.21396","article-title":"Height deficit during and many years after treatment for acute lymphoblastic leukemia in children: a review","volume":"50","author":"Viana","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib14","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jpeds.2006.11.036","article-title":"Decreased adult height in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study","volume":"150","author":"Chow","year":"2007","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.pcl.2020.08.002_bib15","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1200\/JCO.2003.03.068","article-title":"Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment","volume":"21","author":"Dalton","year":"2003","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib16","doi-asserted-by":"crossref","first-page":"4731","DOI":"10.1210\/jc.2003-030784","article-title":"Final height and body mass index among adult survivors of childhood brain cancer: Childhood Cancer Survivor Study","volume":"88","author":"Gurney","year":"2003","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib17","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1210\/jc.2012-4075","article-title":"Endocrine side effects induced by immune checkpoint inhibitors","volume":"98","author":"Corsello","year":"2013","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib18","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1002\/pbc.24397","article-title":"Growth failure in children with chronic myeloid leukemia receiving imatinib is due to disruption of GH\/IGF-1 axis","volume":"60","author":"Narayanan","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib19","doi-asserted-by":"crossref","first-page":"e0131192","DOI":"10.1371\/journal.pone.0131192","article-title":"Impact of long-term exposure to the tyrosine kinase inhibitor imatinib on the skeleton of growing rats","volume":"10","author":"Tauer","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.pcl.2020.08.002_bib20","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/cen.13063","article-title":"Immune checkpoint inhibitor-related hypophysitis and endocrine dysfunction: clinical review","volume":"85","author":"Joshi","year":"2016","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.pcl.2020.08.002_bib21","doi-asserted-by":"crossref","first-page":"R233","DOI":"10.1677\/ERC-10-0082","article-title":"Endocrine side effects of broad-acting kinase inhibitors","volume":"17","author":"Lodish","year":"2010","journal-title":"Endocr Relat Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib22","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jpeds.2011.03.046","article-title":"Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia","volume":"159","author":"Shima","year":"2011","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.pcl.2020.08.002_bib23","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/pbc.24121","article-title":"Imatinib mesylate causes growth deceleration in pediatric patients with chronic myelogenous leukemia","volume":"59","author":"Rastogi","year":"2012","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib24","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1515\/JPEM.2004.17.5.711","article-title":"Auxologic and biochemical characterization of the three phases of growth failure in pediatric patients with brain tumors","volume":"17","author":"Meacham","year":"2004","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib25","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1002\/pbc.26180","article-title":"Skeletal impact of retinoid therapy in childhood cancer survivors","volume":"63","author":"Mostoufi-Moab","year":"2016","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib26","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0936-6555(05)80744-7","article-title":"The evolution of spinal growth after irradiation","volume":"3","author":"Clayton","year":"1991","journal-title":"Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib27","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1210\/jc.2018-01175","article-title":"Hypothalamic\u2013pituitary and growth disorders in survivors of childhood cancer: an Endocrine Society Clinical Practice Guideline","volume":"103","author":"Sklar","year":"2018","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib28","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1210\/jcem.87.7.8606","article-title":"Risk of disease recurrence and second neoplasms in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study","volume":"87","author":"Sklar","year":"2002","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib29","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1210\/jc.2006-0656","article-title":"Growth hormone treatment and risk of second neoplasms in the childhood cancer survivor","volume":"91","author":"Ergun-Longmire","year":"2006","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib30","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1530\/EJE-12-0967","article-title":"Incidence of second neoplasm in childhood cancer survivors treated with GH: an analysis of GeNeSIS and HypoCCS","volume":"168","author":"Woodmansee","year":"2013","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.pcl.2020.08.002_bib31","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1210\/jc.2015-1002","article-title":"Risk of neoplasia in pediatric patients receiving growth hormone therapy - a report from the pediatric Endocrine Society Drug and Therapeutics Committee","volume":"100","author":"Raman","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib32","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1210\/jc.2011-0112","article-title":"Long-term safety of growth hormone replacement after CNS irradiation","volume":"96","author":"Mackenzie","year":"2011","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s40618-014-0179-1","article-title":"GH replacement therapy and second neoplasms in adult survivors of childhood cancer: a retrospective study from a single institution","volume":"38","author":"Brignardello","year":"2015","journal-title":"J\u00a0Endocrinol Invest"},{"key":"10.1016\/j.pcl.2020.08.002_bib34","doi-asserted-by":"crossref","first-page":"P1","DOI":"10.1530\/EJE-15-0873","article-title":"GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults","volume":"174","author":"Allen","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.pcl.2020.08.002_bib35","doi-asserted-by":"crossref","first-page":"4422","DOI":"10.1210\/jc.2004-0160","article-title":"Factors that affect final height and change in height standard deviation scores in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study","volume":"89","author":"Brownstein","year":"2004","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib36","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1200\/JCO.2013.52.2268","article-title":"Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study","volume":"31","author":"Ness","year":"2013","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib37","doi-asserted-by":"crossref","first-page":"3888","DOI":"10.1210\/jc.2016-2118","article-title":"Hormonal replacement in hypopituitarism in adults: an Endocrine Society Clinical Practice Guideline","volume":"101","author":"Fleseriu","year":"2016","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib38","doi-asserted-by":"crossref","first-page":"4998","DOI":"10.1210\/jc.2019-00539","article-title":"Clinical importance of free thyroxine concentration decline after radiotherapy for pediatric and adolescent brain tumors","volume":"104","author":"van Iersel","year":"2019","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib39","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1002\/pbc.22208","article-title":"Adrenal function testing in pediatric cancer survivors","volume":"53","author":"Patterson","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib40","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1200\/JCO.1990.8.12.1981","article-title":"Effects of radiation on testicular function in long-term survivors of childhood acute lymphoblastic leukemia: a report from the Children Cancer Study Group","volume":"8","author":"Sklar","year":"1990","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib41","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/cen.12964","article-title":"Central precocious puberty following the diagnosis and treatment of paediatric cancer and central nervous system tumours: presentation and long-term outcomes","volume":"84","author":"Chemaitilly","year":"2016","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.pcl.2020.08.002_bib42","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1056\/NEJM199301143280203","article-title":"Hypothalamic-pituitary dysfunction after radiation for brain tumors","volume":"328","author":"Constine","year":"1993","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.pcl.2020.08.002_bib43","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000336333","article-title":"Diabetes insipidus - diagnosis and management","volume":"77","author":"Di Iorgi","year":"2012","journal-title":"Horm Res Paediatrics"},{"issue":"Suppl 3","key":"10.1016\/j.pcl.2020.08.002_bib44","first-page":"S180","article-title":"Management of diabetes insipidus in children","volume":"15","author":"Mishra","year":"2011","journal-title":"Indian J Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib45","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000495040","article-title":"Thyroid sequelae of pediatric cancer therapy","volume":"91","author":"Waguespack","year":"2019","journal-title":"Horm Res Paediatrics"},{"key":"10.1016\/j.pcl.2020.08.002_bib46","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/0360-3016(95)00019-U","article-title":"Thyroid abnormalities after therapeutic external radiation","volume":"31","author":"Hancock","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.pcl.2020.08.002_bib47","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJM199108293250902","article-title":"Thyroid diseases after treatment of Hodgkin\u2019s disease","volume":"325","author":"Hancock","year":"1991","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.pcl.2020.08.002_bib48","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ijrobp.2019.02.009","article-title":"Hyperthyroidism after radiation therapy for childhood cancer: a report from the Childhood Cancer Survivor Study","volume":"104","author":"Inskip","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.pcl.2020.08.002_bib49","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ctrv.2003.12.003","article-title":"Radiotherapy-induced thyroid disorders","volume":"30","author":"Jereczek-Fossa","year":"2004","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.pcl.2020.08.002_bib50","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1007\/s00259-014-2967-4","article-title":"Long-term efficacy of current thyroid prophylaxis and future perspectives on thyroid protection during 131I-metaiodobenzylguanidine treatment in children with neuroblastoma","volume":"42","author":"Clement","year":"2015","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.pcl.2020.08.002_bib51","first-page":"3227","article-title":"Abnormalities of the thyroid in survivors of Hodgkin\u2019s disease: data from the childhood cancer survivor study","volume":"85","author":"Sklar","year":"2000","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib52","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1038\/sj.bmt.1704945","article-title":"Late thyroid toxicity in 153 long-term survivors of allogeneic bone marrow transplantation for acute lymphoblastic leukaemia","volume":"35","author":"Berger","year":"2005","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.pcl.2020.08.002_bib53","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1365-2265.2007.02813.x","article-title":"Thyroid function in paediatric and young adult patients after sarcoma therapy: a report from the Late Effects Surveillance System","volume":"66","author":"Paulides","year":"2007","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.pcl.2020.08.002_bib54","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1182\/blood-2008-08-173005","article-title":"Thyroid function following hematopoietic cell transplantation in children: 30 years\u2019 experience","volume":"113","author":"Sanders","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.pcl.2020.08.002_bib55","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1158\/1055-9965.EPI-11-0576","article-title":"Chemotherapy and thyroid cancer risk: a report from the Childhood Cancer Survivor Study","volume":"21","author":"Veiga","year":"2012","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.pcl.2020.08.002_bib56","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1515\/jpem-2018-0020","article-title":"Long-term thyroid disorders in pediatric survivors of hematopoietic stem cell transplantation after chemotherapy-only conditioning","volume":"31","author":"Cima","year":"2018","journal-title":"J\u00a0Pediatr Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib57","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nrclinonc.2009.4","article-title":"Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy","volume":"6","author":"Torino","year":"2009","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib58","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ctrv.2017.11.005","volume":"63","author":"Clement","year":"2018","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.pcl.2020.08.002_bib59","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1667\/RR2240.1","article-title":"Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the Childhood Cancer Survivor Study","volume":"174","author":"Bhatti","year":"2010","journal-title":"Radiat Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib60","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1089\/thy.2011.0464","article-title":"Differentiated thyroid carcinoma after 131I-MIBG treatment for neuroblastoma during childhood: description of the first two cases","volume":"22","author":"van Santen","year":"2012","journal-title":"Thyroid"},{"key":"10.1016\/j.pcl.2020.08.002_bib61","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/bjc.1992.87","article-title":"Epidemiological evidence for a common mechanism for neuroblastoma and differentiated thyroid tumour","volume":"65","author":"de Vathaire","year":"1992","journal-title":"Br J Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib62","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1667\/RR14213.1","article-title":"Thyroid cancer after childhood exposure to external radiation: an updated pooled analysis of 12 studies","volume":"185","author":"Veiga","year":"2016","journal-title":"Radiat Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib63","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1667\/RR2889.1","article-title":"A\u00a0pooled analysis of thyroid cancer incidence following radiotherapy for childhood cancer","volume":"178","author":"Veiga","year":"2012","journal-title":"Radiat Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib64","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1002\/cncr.11362","article-title":"Thyroid neoplasms after therapeutic radiation for malignancies during childhood or adolescence","volume":"97","author":"Acharya","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib65","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ctrv.2014.10.009","article-title":"Is outcome of differentiated thyroid carcinoma influenced by tumor stage at diagnosis?","volume":"41","author":"Clement","year":"2015","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.pcl.2020.08.002_bib66","article-title":"Traditional cardiovascular risk factors and individual prediction of cardiovascular events in childhood cancer survivors","author":"Chen","year":"2019","journal-title":"J\u00a0Natl Cancer Inst"},{"key":"10.1016\/j.pcl.2020.08.002_bib67","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1200\/JCO.2013.49.3205","article-title":"Modifiable risk factors and major cardiac events among adult survivors of childhood cancer","volume":"31","author":"Armstrong","year":"2013","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib68","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1001\/jamainternmed.2015.1180","article-title":"Cardiovascular disease after Hodgkin lymphoma treatment: 40-year disease risk","volume":"175","author":"Van Nimwegen","year":"2015","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.pcl.2020.08.002_bib69","first-page":"3051","article-title":"Long-term survivors of childhood cancer have an increased risk of manifesting the metabolic syndrome","volume":"81","author":"Talvensaari","year":"1996","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib70","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1002\/cncr.28670","article-title":"Lifestyle and metabolic syndrome in adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study","volume":"120","author":"Smith","year":"2014","journal-title":"Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib71","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1194\/jlr.P029785","article-title":"Atherogenic low density lipoprotein phenotype in long-term survivors of childhood acute lymphoblastic leukemia","volume":"53","author":"Malhotra","year":"2012","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib72","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1158\/1055-9965.EPI-09-0555","article-title":"Cardiovascular risk factors in adult survivors of pediatric cancer-a report from the childhood cancer survivor study","volume":"19","author":"Meacham","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.pcl.2020.08.002_bib73","first-page":"65","article-title":"Endocrine late effects of childhood cancer therapy: a report from the children\u2019s oncology group","volume":"69","author":"Nandagopal","year":"2008","journal-title":"Horm Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib74","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.pcl.2020.08.002_bib75","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1530\/eje.0.1430243","article-title":"Anthropometric parameters and their relationship to serum growth hormone-binding protein and leptin levels in children with acute lymphoblastic leukemia: a prospective study","volume":"143","author":"Arguelles","year":"2000","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.pcl.2020.08.002_bib76","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1002\/pbc.24703","article-title":"Metabolic syndrome in pediatric cancer survivors: a mechanistic review","volume":"60","author":"Rosen","year":"2013","journal-title":"Pediatr Blood Cancer"},{"issue":"4","key":"10.1016\/j.pcl.2020.08.002_bib77","doi-asserted-by":"crossref","first-page":"e26344","DOI":"10.1002\/pbc.26344","article-title":"Changes in body mass index in long-term survivors of childhood acute lymphoblastic leukemia treated without cranial radiation and with reduced glucocorticoid therapy","volume":"64","author":"Touyz","year":"2017","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib78","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/cncr.22120","article-title":"Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia","volume":"107","author":"Gurney","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib79","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1001\/archinternmed.2009.209","article-title":"Diabetes mellitus in long-term survivors of childhood cancer - increased risk associated with radiation therapy: a report for the childhood cancer survivor study","volume":"169","author":"Meacham","year":"2009","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.pcl.2020.08.002_bib80","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1297\/cpe.26.99","article-title":"Partial lipodystrophy in patients who have undergone hematopoietic stem cell transplantation during childhood: an institutional cross-sectional survey","volume":"26","author":"Adachi","year":"2017","journal-title":"Clin Pediatr Endocrinol"},{"key":"10.1016\/j.pcl.2020.08.002_bib81","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1158\/1055-9965.EPI-07-0048","article-title":"Physical inactivity in adult survivors of childhood acute lymphoblastic leukemia: a report from the childhood cancer survivor study","volume":"16","author":"Florin","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.pcl.2020.08.002_bib82","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/pbc.24049","article-title":"Effects of a home-based exercise program on metabolic risk factors and fitness in long-term survivors of childhood acute lymphoblastic leukemia","volume":"59","author":"J\u00e4rvel\u00e4","year":"2012","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib83","first-page":"313","article-title":"Contribution of diet and physical activity to metabolic parameters among survivors of childhood leukemia","volume":"24","author":"Tonorezos","year":"2013","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.pcl.2020.08.002_bib84","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000494809","article-title":"Skeletal morbidity in children and adolescents during and following cancer therapy","volume":"91","author":"Mostoufi-Moab","year":"2019","journal-title":"Horm Res Paediatrics"},{"key":"10.1016\/j.pcl.2020.08.002_bib85","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1200\/JCO.2017.76.3268","article-title":"Endocrine late effects in childhood cancer survivors","volume":"36","author":"Chemaitilly","year":"2018","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.pcl.2020.08.002_bib86","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s11914-014-0222-3","article-title":"Bone morbidity in childhood leukemia: epidemiology, mechanisms, diagnosis, and treatment","volume":"12","author":"Mostoufi-Moab","year":"2014","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.pcl.2020.08.002_bib87","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1210\/JC.2015-2176","article-title":"Incident vertebral fractures in children with leukemia during the four years following diagnosis","volume":"100","author":"Cummings","year":"2015","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.pcl.2020.08.002_bib88","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/pbc.25010","article-title":"Bone mineral density among long-term survivors of childhood acute lymphoblastic leukemia: results from the St. Jude Lifetime Cohort Study","volume":"61","author":"Gurney","year":"2014","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib89","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1002\/jbmr.1499","article-title":"Bone density and structure in long-term survivors of pediatric allogeneic hematopoietic stem cell transplantation","volume":"27","author":"Mostoufi-Moab","year":"2012","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.pcl.2020.08.002_bib90","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jocd.2014.01.003","article-title":"Dual-energy x-ray absorptiometry interpretation and reporting in children and adolescents: the revised 2013 ISCD pediatric official positions","volume":"17","author":"Crabtree","year":"2014","journal-title":"J\u00a0Clin Densitom"},{"key":"10.1016\/j.pcl.2020.08.002_bib91","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1001\/jama.2013.6296","article-title":"Clinical ascertainment of health outcomes among adults treated for childhood cancer","volume":"309","author":"Hudson","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.pcl.2020.08.002_bib92","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/pbc.21405","article-title":"Osteonecrosis in children and adolescents with cancer","volume":"50","author":"Barr","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.pcl.2020.08.002_bib93","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/pbc.24563","article-title":"Use of zoledronic acid for treatment of chemotherapy related osteonecrosis in children and adolescents: a retrospective analysis","volume":"60","author":"Padhye","year":"2013","journal-title":"Pediatr Blood Cancer"}],"container-title":["Pediatric Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031395520301103?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031395520301103?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:23:50Z","timestamp":1758475430000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031395520301103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":93,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S0031395520301103"],"URL":"https:\/\/doi.org\/10.1016\/j.pcl.2020.08.002","relation":{},"ISSN":["0031-3955"],"issn-type":[{"value":"0031-3955","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endocrine Health in Childhood Cancer Survivors","name":"articletitle","label":"Article Title"},{"value":"Pediatric Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pcl.2020.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}