{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:49:55Z","timestamp":1790639395992,"version":"4.1.0"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"The Scientific and Technological Research Council of Turkey"},{"DOI":"10.13039\/501100003093","name":"the Ministry of Higher Education, Malaysia","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.pdpdt.2016.07.008","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T17:35:43Z","timestamp":1469727343000},"page":"12-14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Iodination improves the phototoxicity of an amphiphilic porphyrin"],"prefix":"10.1016","volume":"16","author":[{"given":"Derya","family":"Topkaya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shie Yin","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Bretonni\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Lafont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lip Yong","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Boon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0388-8338","authenticated-orcid":false,"given":"Fabienne","family":"Dumoulin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pdpdt.2016.07.008_bib0005","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1751-1097.1996.tb03093.x","article-title":"Structure and biodistribution relationships of photodynamic sensitizers","volume":"64","author":"Boyle","year":"1996","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0010","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jphotobiol.2012.08.012","article-title":"Systems biology approach for in vivo photodynamic therapy optimization of ruthenium-porphyrin compounds","volume":"117","author":"Pernot","year":"2012","journal-title":"J. Photochem. Photobiol. B: Biol."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0015","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1142\/S1088424615300037","article-title":"Porphyrin-based photosensitizers and the corresponding multifunctional nanoplatforms for cancer-imaging and phototherapy","volume":"19","author":"Srivatsan","year":"2015","journal-title":"J. Porphyr. Phthalocya."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0020","doi-asserted-by":"crossref","first-page":"15304","DOI":"10.1039\/C5CC06985H","article-title":"Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic","volume":"51","author":"Maruani","year":"2015","journal-title":"Chem. Comm."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0025","doi-asserted-by":"crossref","first-page":"e97894","DOI":"10.1371\/journal.pone.0097894","article-title":"Improved photodynamic efficacy of Zn(II) phthalocyanines via glycerol substitution","volume":"9","author":"Chin","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0030","doi-asserted-by":"crossref","first-page":"2865","DOI":"10.1021\/jm901823u","article-title":"In vitro and In vivo photocytotoxicity of boron dipyrromethene derivatives for photodynamic therapy","volume":"53","author":"Lim","year":"2010","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0035","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1142\/S1088424615500893","article-title":"Modulation of singlet oxygen generation and amphiphilic properties of trihydroxylated monohalogenated porphyrins","volume":"19","author":"Topkaya","year":"2015","journal-title":"J. Porphyr. Phthalocya."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0040","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1039\/C5NJ02716K","article-title":"Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity","volume":"40","author":"Topkaya","year":"2016","journal-title":"N. J. Chem."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0045","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1021\/jo01288a053","article-title":"A simplified synthesis for meso-tetraphenylporphin","volume":"32","author":"Adler","year":"1967","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0050","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0169-409X(96)00423-1","article-title":"Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings","volume":"23","author":"Lipinski","year":"1997","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0055","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.pdpdt.2008.02.001","article-title":"Bio-nanotechnology and photodynamic therapy \u2212 state of the art review","volume":"5","author":"Allison","year":"2008","journal-title":"Photodiagn. Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2016.07.008_bib0060","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1021\/j100373a096","article-title":"Comment on Effect of solvent on the phosphorescence rate constant of singlet molecular oxygen (1\u25b3g)","volume":"94","author":"Schmidt","year":"1990","journal-title":"J. Phys. Chem."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100016300618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100016300618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:25:51Z","timestamp":1761611151000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100016300618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":12,"alternative-id":["S1572100016300618"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2016.07.008","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iodination improves the phototoxicity of an amphiphilic porphyrin","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2016.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}