{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T10:13:02Z","timestamp":1769854382481,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.pdpdt.2019.09.010","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T01:41:54Z","timestamp":1570066914000},"page":"101565","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["The effectiveness of photodynamic therapy as a complementary therapy to mechanical instrumentation on residual periodontal pocket clinical parameters: A clinical split-mouth test"],"prefix":"10.1016","volume":"29","author":[{"given":"Nat\u00e1lia Teixeira da","family":"Siva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davi Neto de Ara\u00fajo","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela Let\u00edcia da Silva","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Leonardo da","family":"Silva J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Linhares","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Paulo Figueir\u00f3","family":"Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maiara de","family":"Moraes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno C\u00e9sar de Vasconcelos","family":"Gurgel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Rafaela Luz","family":"de Aquino Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.pdpdt.2019.09.010_bib0005","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1590\/S0103-05822010000200017","article-title":"Periodontal problems associated with systemic diseases in children and adolescents","volume":"28","author":"Vieira","year":"2010","journal-title":"Rev. Paul. Pediatr."},{"issue":"2","key":"10.1016\/j.pdpdt.2019.09.010_bib0010","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jphotobiol.2004.11.023","article-title":"Photodynamic therapy for periodontal diseases: state of the art","volume":"79","author":"Meisel","year":"2005","journal-title":"J. Photochem. Photobiol. B"},{"issue":"9","key":"10.1016\/j.pdpdt.2019.09.010_bib0015","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1902\/jop.2014.130464","article-title":"Effects of photodynamic therapy on clinical and gingival crevicular fluid in\ufb02ammatory biomarkers in chronic periodontitis: a split-mouth randomized clinical trial","volume":"85","author":"Pourabbas","year":"2014","journal-title":"J. Periodontol."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0020","series-title":"Terapia fotodin\u00e2mica no tratamento de bolsas residuais de pacientes em manuten\u00e7\u00e3o periodontal: ensaio cl\u00ednico aleat\u00f3rio controlado. Doctoral dissertation","author":"Carvalho","year":"2014"},{"issue":"4","key":"10.1016\/j.pdpdt.2019.09.010_bib0025","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1177\/154405910508400409","article-title":"Initial subgingival colonization of \u2018pristine\u2019pockets","volume":"84","author":"Quirynen","year":"2005","journal-title":"J. Dent. Res."},{"issue":"6","key":"10.1016\/j.pdpdt.2019.09.010_bib0030","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1111\/jcpe.12545","article-title":"Clinical efficacy of probiotics as an adjunctive therapy to non\u2010surgical periodontal treatment of chronic periodontitis: a systematic review and meta\u2010analysis","volume":"43","author":"Cabezas","year":"2016","journal-title":"J. Clin. Periodontol."},{"issue":"3","key":"10.1016\/j.pdpdt.2019.09.010_bib0035","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S1532-3382(12)70019-2","article-title":"Nonsurgical treatment of periodontitis","volume":"12","author":"Sanz","year":"2012","journal-title":"J. Evid. Dent. Pract."},{"issue":"1","key":"10.1016\/j.pdpdt.2019.09.010_bib0040","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1902\/jop.2009.070465","article-title":"Antimicrobial photodynamic therapy in the non-surgical treatment of aggressive periodontitis: cytokine profile in gingival crevicular fluid, preliminary results","volume":"80","author":"Oliveira","year":"2009","journal-title":"J. Periodontol."},{"issue":"5","key":"10.1016\/j.pdpdt.2019.09.010_bib0045","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s10103-008-0565-z","article-title":"Photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial","volume":"24","author":"Chondros","year":"2009","journal-title":"Lasers Med. Sci."},{"issue":"8","key":"10.1016\/j.pdpdt.2019.09.010_bib0050","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/j.1600-051X.2008.01245.x","article-title":"Influence of residual pockets on progression of periodontitis and tooth loss: results after 11 years of maintenance","volume":"35","author":"Matuliene","year":"2008","journal-title":"J. Clin. Periodontol."},{"issue":"4","key":"10.1016\/j.pdpdt.2019.09.010_bib0055","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1902\/jop.1996.67.4.367","article-title":"Effectiveness of subgingival scaling and root planing: single versus multiple episodes of instrumentation","volume":"67","author":"Anderson","year":"1996","journal-title":"J. Periodontol."},{"issue":"8","key":"10.1016\/j.pdpdt.2019.09.010_bib0060","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1034\/j.1600-051x.2000.027008590.x","article-title":"Effect of subgingival scaling during supportive therapy","volume":"27","author":"Jenkins","year":"2000","journal-title":"J. Clin. Periodontol."},{"issue":"4","key":"10.1016\/j.pdpdt.2019.09.010_bib0065","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10103-007-0482-6","article-title":"Nd: YAG laser clinical assisted in class II furcation treatment","volume":"23","author":"Andrade","year":"2008","journal-title":"Lasers Med. Sci."},{"issue":"50","key":"10.1016\/j.pdpdt.2019.09.010_bib0070","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1600-0757.2008.00283.x","article-title":"Application of lasers in periodontics: true innovation or myth?","volume":"2000","author":"Ishikawa","year":"2009","journal-title":"Periodontol"},{"issue":"2","key":"10.1016\/j.pdpdt.2019.09.010_bib0075","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s10103-013-1426-y","article-title":"Long-term clinical effect of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial","volume":"30","author":"Alwaeli","year":"2015","journal-title":"Lasers Med. Sci."},{"issue":"3","key":"10.1016\/j.pdpdt.2019.09.010_bib0080","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jphotobiol.2010.08.007","article-title":"Impact of photodynamic therapy on inflammatory cells during human chronic periodontitis","volume":"101","author":"S\u00e9guier","year":"2010","journal-title":"J. Photochem. Photobiol. B"},{"issue":"3","key":"10.1016\/j.pdpdt.2019.09.010_bib0085","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1902\/jop.2014.140392","article-title":"Antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of aggressive periodontitis: a split-mouth randomized controlled trial","volume":"86","author":"Moreira","year":"2015","journal-title":"J. Periodontol."},{"issue":"6","key":"10.1016\/j.pdpdt.2019.09.010_bib0090","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1111\/jcpe.12249","article-title":"Efficacy of photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial","volume":"41","author":"Betsy","year":"2014","journal-title":"J. Clin. Periodontol."},{"issue":"5","key":"10.1016\/j.pdpdt.2019.09.010_bib0095","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/jcpe.12393","article-title":"Antimicrobial photodynamic effect to treat residual pockets in periodontal patients: a randomized controlled clinical trial","volume":"42","author":"Carvalho","year":"2015","journal-title":"J. Clin. Periodontol."},{"issue":"5","key":"10.1016\/j.pdpdt.2019.09.010_bib0100","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s10103-011-1027-6","article-title":"Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling. A randomized, split-mouth controlled clinical trial","volume":"27","author":"Cappuyns","year":"2012","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0105","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.2147\/IJN.S57420","article-title":"Aluminum-phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy","volume":"9","author":"Muehlmann","year":"2014","journal-title":"Int. J. Nanomed. Nanosurg."},{"issue":"6","key":"10.1016\/j.pdpdt.2019.09.010_bib0110","first-page":"341","article-title":"Subgingival topical doxycycline versus mechanical debridement for supportive periodontal therapy: a single blind randomized controlled two-center study","volume":"18","author":"Eickholz","year":"2005","journal-title":"Am. J. Dent."},{"issue":"1","key":"10.1016\/j.pdpdt.2019.09.010_bib0115","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10103-012-1159-3","article-title":"The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial","volume":"28","author":"Campos","year":"2013","journal-title":"Lasers Med. Sci."},{"issue":"4","key":"10.1016\/j.pdpdt.2019.09.010_bib0120","doi-asserted-by":"crossref","first-page":"220","DOI":"10.15171\/jlms.2016.39","article-title":"Effect of antimicrobial photodynamic therapy as an adjunct to nonsurgical treatment of deep periodontal pockets: a clinical study","volume":"7","author":"Ahad","year":"2016","journal-title":"J. Lasers Med. Sci."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0125","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.pdpdt.2017.03.017","article-title":"Effects of root debridement and adjunctive photodynamic therapy in residual pockets of patients on supportive periodontal therapy: a randomized split-mouth trial","volume":"18","author":"Goh","year":"2017","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0130","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1746-160X-8-12","article-title":"Comparison between scaling-rootplaning (SRP) and SRP\/photodynamic therapy: six-month study","volume":"8","author":"Berakdar","year":"2012","journal-title":"Head Face Med."},{"issue":"9","key":"10.1016\/j.pdpdt.2019.09.010_bib0135","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1902\/jop.2008.070652","article-title":"Photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial","volume":"79","author":"Christodoulides","year":"2008","journal-title":"J. Periodontol."},{"issue":"3","key":"10.1016\/j.pdpdt.2019.09.010_bib0140","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1089\/1549541041438623","article-title":"The efficacy of laser therapy in wound repair: a meta-analysis of the literature","volume":"22","author":"Woodruff","year":"2004","journal-title":"Photomed. Laser Surg."},{"issue":"8","key":"10.1016\/j.pdpdt.2019.09.010_bib0145","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1902\/jop.2014.130559","article-title":"Photodynamic therapy during supportive periodontal care: clinical, microbiologic, immunoinflammatory, and patient-centered performance in a split-mouth randomized clinical trial","volume":"85","author":"Kolbe","year":"2014","journal-title":"J. Periodontol."},{"issue":"2","key":"10.1016\/j.pdpdt.2019.09.010_bib0150","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1902\/jop.2007.060312","article-title":"Comparative study of ultrasonic instrumentation for the non-surgical treatment of interproximal and non-interproximal furcation involvements","volume":"78","author":"Ribeiro","year":"2007","journal-title":"J. Periodontol."},{"issue":"2","key":"10.1016\/j.pdpdt.2019.09.010_bib0155","first-page":"89","article-title":"Influence of compliance and smoking habits on the outcomes of supportive periodontal therapy (SPT) in a private practice","volume":"2","author":"Rieder","year":"2004","journal-title":"Oral Health Prev. Dent."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0160","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00784-009-0347-4","article-title":"Photodynamic therapy of persistent pockets in maintenance patients \u2013 a clinical study","volume":"14","author":"R\u00fchling","year":"2010","journal-title":"Clin Oral Invest"},{"issue":"8","key":"10.1016\/j.pdpdt.2019.09.010_bib0165","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1600-051X.2009.01432.x","article-title":"One-year outcomes of repeated adjunctive photodynamic therapy during periodontal maintenance: a proof-of-principle randomized-controlled clinical trial","volume":"36","author":"Lulic","year":"2009","journal-title":"J. Clin. Periodontol."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0170","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s10103-013-1337-y","article-title":"Single or repeated antimicrobial photodynamic therapy as adjunct to ultrasonic debridement in residual periodontal pockets: clinical, microbiological, and local biological effects","volume":"30","author":"Campanille","year":"2015","journal-title":"Lasers Med. Sci."},{"issue":"1","key":"10.1016\/j.pdpdt.2019.09.010_bib0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10103-012-1225-x","article-title":"Light-activated disinfection using a light-emitting diode lamp in the red spectrum: clinical and microbiological short-term findings on periodontitis patients in maintenance. A randomized controlled split-mouth clinical trial","volume":"29","author":"Mongardini","year":"2014","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.pdpdt.2019.09.010_bib0180","series-title":"An\u00e1lise Imunoistoqu\u00edmica Ap\u00f3s Terapia Fotodin\u00e2mica Com Cloro-alum\u00ednio Ftalocianina Em Tecidos Gengivais De Humanos. Doctoral Dissertation","author":"Moraes","year":"2014"},{"issue":"3","key":"10.1016\/j.pdpdt.2019.09.010_bib0185","first-page":"147","article-title":"Aplicaci\u00f3n complementaria de terapia fotodin\u00e1mica y de la radiaci\u00f3n l\u00e1ser de Er:YAG al tratamiento no quir\u00fargico de la periodontitis cr\u00f3nica: estudio comparativo de sus efectos cl\u00ednicos, antiinflamatorios y antimicrobianos","volume":"27","author":"G\u00f3mez","year":"2011","journal-title":"Av. Odontoestomatol."},{"issue":"9","key":"10.1016\/j.pdpdt.2019.09.010_bib0190","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1902\/jop.2003.74.9.1293","article-title":"Pain experienced by patients during periodontal maintenance","volume":"74","author":"Chung","year":"2003","journal-title":"J. Periodontol."},{"issue":"6","key":"10.1016\/j.pdpdt.2019.09.010_bib0195","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1600-0765.2008.01187.x","article-title":"The antibacterial effect of photodynamic therapy in dental plaque-derived biofilms","volume":"44","author":"Fontana","year":"2009","journal-title":"J. Periodontal Res. Suppl."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100019302790?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100019302790?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:32:20Z","timestamp":1761611540000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100019302790"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":39,"alternative-id":["S1572100019302790"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2019.09.010","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effectiveness of photodynamic therapy as a complementary therapy to mechanical instrumentation on residual periodontal pocket clinical parameters: A clinical split-mouth test","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2019.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101565"}}