{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:09:24Z","timestamp":1791389364237,"version":"4.3.3"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100014137","name":"Shanghai Shenkang Hospital Development Center","doi-asserted-by":"publisher","award":["SHDC12019130"],"award-info":[{"award-number":["SHDC12019130"]}],"id":[{"id":"10.13039\/501100014137","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.pdpdt.2020.101915","type":"journal-article","created":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T18:33:34Z","timestamp":1593887614000},"page":"101915","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Modified photodynamic therapy to minimize pain in the treatment of condylomata acuminata: A prospective, randomized, self-controlled study"],"prefix":"10.1016","volume":"32","author":[{"given":"Haiyan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiru","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guolong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajing","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongxia","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuli","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.pdpdt.2020.101915_bib0005","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1001\/jama.2018.20181","article-title":"Genital Warts","volume":"321","author":"Grennan","year":"2019","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.pdpdt.2020.101915_bib0010","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1365-2133.2006.07648.x","article-title":"Comparative study of photodynamic therapy vs CO2 laser vaporization in treatment of condylomata acuminata: a randomized clinical trial","volume":"156","author":"Chen","year":"2007","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.pdpdt.2020.101915_bib0015","first-page":"26","article-title":"Photodynamic therapy in the clinical practice","volume":"5","author":"Filonenko","year":"2016","journal-title":"Biomed. Photon."},{"issue":"Suppl 3","key":"10.1016\/j.pdpdt.2020.101915_bib0020","doi-asserted-by":"crossref","first-page":"e280","DOI":"10.1016\/j.ijid.2009.11.031","article-title":"Treatment of anogenital condylomata acuminata with topical photodynamic therapy: report of 14 cases and review","volume":"14","author":"Nucci","year":"2010","journal-title":"Int. J. Infect. Dis."},{"issue":"5","key":"10.1016\/j.pdpdt.2020.101915_bib0025","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1111\/j.1365-2133.2003.05553.x","article-title":"In vivo fluorescence kinetics and photodynamic therapy in condylomata acuminata","volume":"149","author":"Stefanaki","year":"2003","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.pdpdt.2020.101915_bib0030","article-title":"5-aminolevulinic photodynamic therapy vs. carbon dioxide laser therapy for small genital warts: a multicenter, randomized, open-label trial","author":"Tu","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"issue":"4","key":"10.1016\/j.pdpdt.2020.101915_bib0035","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1365-2133.2004.06189.x","article-title":"Topical 5-aminolaevulinic acid-photodynamic therapy for the treatment of urethral condylomata acuminata","volume":"151","author":"Wang","year":"2004","journal-title":"Br. J. Dermatol."},{"issue":"4","key":"10.1016\/j.pdpdt.2020.101915_bib0040","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.pdpdt.2008.11.004","article-title":"Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region","volume":"5","author":"Wang","year":"2008","journal-title":"Photodiagn. Photodyn. Ther."},{"issue":"5","key":"10.1016\/j.pdpdt.2020.101915_bib0045","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1751-1097.2007.00178.x","article-title":"Study of protoporphyrin IX (PpIX) pharmacokinetics after topical application of 5-aminolevulinic acid in urethral condylomata acuminata","volume":"83","author":"Wang","year":"2007","journal-title":"Photochem. Photobiol."},{"issue":"10","key":"10.1016\/j.pdpdt.2020.101915_bib0050","first-page":"675","article-title":"Expert consensus on the clinical application of aminolevulinic acid photodynamic therapy","volume":"48","author":"XLea","year":"2015","journal-title":"Chin. J. Dermatol."},{"key":"10.1016\/j.pdpdt.2020.101915_bib0055","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pdpdt.2019.03.001","article-title":"What is the most relevent factor causing pain during ALA-PDT? A multi-center, open clinical pain score research trial of actinic keratosis, acne and condylomata acuminata","volume":"26","author":"Zheng","year":"2019","journal-title":"Photodiagn. Photodyn. Ther."},{"issue":"3","key":"10.1016\/j.pdpdt.2020.101915_bib0060","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/bjd.15344","article-title":"Gain with no pain? Pain management in dermatological photodynamic therapy","volume":"177","author":"Wang","year":"2017","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.pdpdt.2020.101915_bib0065","first-page":"19","article-title":"In-office painless aminolevulinic acid photodynamic therapy: a proof of concept study and clinical experience in more than 100 patients","volume":"9","author":"Martin","year":"2016","journal-title":"J. Clin. Aesth. Dermatol."},{"issue":"4","key":"10.1016\/j.pdpdt.2020.101915_bib0070","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.jaad.2019.09.010","article-title":"A regimen to minimize pain during blue light photodynamic therapy of actinic keratoses: bilaterally controlled, randomized trial of simultaneous versus conventional illumination","volume":"82","author":"Kaw","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"issue":"5","key":"10.1016\/j.pdpdt.2020.101915_bib0075","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1039\/c5pp00069f","article-title":"Correlation between treatment time, photobleaching, inflammation and pain after photodynamic therapy with methyl aminolevulinate on tape-stripped skin in healthy volunteers","volume":"14","author":"Lerche","year":"2015","journal-title":"Photochem. Photobiol. Sci."},{"issue":"6","key":"10.1016\/j.pdpdt.2020.101915_bib0080","doi-asserted-by":"crossref","first-page":"793","DOI":"10.23736\/S0392-0488.18.06011-X","article-title":"Pain perception during photodynamic therapy: why is daylight PDT with methyl aminolevulinate almost pain-free? A review on the underlying mechanisms, clinical reflections and resulting opportunities","volume":"153","author":"Szeimies","year":"2018","journal-title":"G. Ital. Dermatol. Venereol."},{"key":"10.1016\/j.pdpdt.2020.101915_bib0085","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ymeth.2016.07.008","article-title":"In situ production of ROS in the skin by photodynamic therapy as a powerful tool in clinical dermatology","volume":"109","author":"Fonda-Pascual","year":"2016","journal-title":"Methods (San Diego, Calif.)"}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100020302696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100020302696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:36:25Z","timestamp":1761611785000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100020302696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":17,"alternative-id":["S1572100020302696"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2020.101915","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modified photodynamic therapy to minimize pain in the treatment of condylomata acuminata: A prospective, randomized, self-controlled study","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2020.101915","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101915"}}