{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:45:53Z","timestamp":1761612353940,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.pdpdt.2020.102171","type":"journal-article","created":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T11:25:03Z","timestamp":1609586703000},"page":"102171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Impact of ocular and systemic risk factors on progression of geographic atrophy in age-related macular degeneration"],"prefix":"10.1016","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8544-103X","authenticated-orcid":false,"given":"Nedime","family":"Sahinoglu-Keskek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Figen","family":"Sermet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"July 24","key":"10.1016\/j.pdpdt.2020.102171_bib0005","article-title":"Retinal pigment epithelium and age-related macular degeneration: a review of major disease mechanisms","author":"Somasundaran","year":"2020","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0010","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.ajo.2008.05.050","article-title":"The epidemiology of progression of pure geographic atrophy: the Beaver Dam Eye Study","volume":"146","author":"Klein","year":"2008","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0015","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ophtha.2004.10.047","article-title":"Age-related eye disease study research group. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study (AREDS) AREDS report no. 19","volume":"112","author":"Clemons","year":"2005","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0020","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.ophtha.2013.11.023","article-title":"Geographic atrophy: clinical features and potential therapeutic approaches","volume":"121","author":"Holz","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0025","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1177\/2474126419859454","article-title":"Percentage of foveal vs total macular geographic atrophy as a predictor of visual acuity in age-related macular degeneration","volume":"3","author":"Bagheri","year":"2019","journal-title":"J Vitreoretin Dis."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0030","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ajo.2006.11.041","article-title":"Progression of geographic atrophy and impact of fundus autofluorescence patterns in age-related macular degeneration","volume":"143","author":"Holz","year":"2007","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0035","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.ophtha.2014.11.007","article-title":"Growth of geographic atrophy in the comparison of age-related macular degeneration treatments trials","volume":"122","author":"Grunwald","year":"2015","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0040","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1097\/IAE.0000000000002480","article-title":"Reclassification of fundus autofluorescence patterns surrounding geographic atrophy based on progression rate: a systematic review and meta-analysis","volume":"39","author":"Shen","year":"2019","journal-title":"Retina"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0045","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.ophtha.2007.04.023","article-title":"Autofluorescence imaging in age-related macular degeneration complicated by choroidal neovascularization: a prospective study","volume":"115","author":"Vaclavik","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0050","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1136\/bjo.2004.057794","article-title":"Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration","volume":"89","author":"Bindewald","year":"2005","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0055","doi-asserted-by":"crossref","DOI":"10.1001\/jamaophthalmol.2019.1318","article-title":"Assessment of novel genome-wide significant gene loci and lesion growth in geographic atrophy secondary to age-related macular degeneration","author":"Grassmann","year":"2019","journal-title":"JAMA Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0060","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.12659\/MSM.915493","article-title":"Age-related macular degeneration and associated risk factors in the population-based study of health in Pomerania (SHIP-Trend)","volume":"25","author":"L\u00fcdtke","year":"2019","journal-title":"Med. Sci. Monit."},{"issue":"May 20","key":"10.1016\/j.pdpdt.2020.102171_bib0065","article-title":"Genotype- and phenotype-based subgroups in geographic atrophy secondary to age-related macular degeneration: the EYE-RISK consortium","volume":"S2468-6530","author":"Biarn\u00e9s","year":"2020","journal-title":"Ophthalmol. Retina"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0070","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1159\/000361077","article-title":"Geographic atrophy progression in eyes with age-related macular degeneration: role of fundus autofluorescence patterns, fellow eye and baseline atrophy area","volume":"52","author":"Batioglu","year":"2014","journal-title":"Ophthalmic Res."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0075","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ophtha.2006.09.016","article-title":"The long-term natural history of geographic atrophy from age-related macular degeneration: enlargement of atrophy and implications for interventional clinical trials","volume":"114","author":"Sunness","year":"2007","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0080","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.oftal.2017.07.004","article-title":"Geographic atrophy: etiopathogenesis and current therapies","volume":"93","author":"Sastre-Ib\u00e1\u00f1ez","year":"2018","journal-title":"Arch. Soc. Esp. Oftalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0085","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1167\/iovs.15-19008","article-title":"Semiautomatic segmentation of rim area focal hyperautofluorescence predicts progression of geographic atrophy due to dry age-related macular degeneration","volume":"57","author":"Allingham","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0090","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ajo.2015.05.009","article-title":"Increased fundus autofluorescence and progression of geographic atrophy secondary to age-related macular degeneration: the GAIN Study","volume":"160","author":"Biarnes","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0095","doi-asserted-by":"crossref","first-page":"235","DOI":"10.4274\/tjo.93276","article-title":"Analysing the progression rates of macular lesions with autofluorescence imaging modes in dry age-related macular degeneration","volume":"45","author":"Olcay","year":"2015","journal-title":"Turk. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0100","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1167\/iovs.11-7298","article-title":"Progression of age-related geographic atrophy: role of the fellow eye","volume":"52","author":"Fleckenstein","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0105","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/S0161-6420(99)00509-6","article-title":"The development of choroidal neovascularization in eyes with the geographic atrophy form of age-related macular degeneration","volume":"106","author":"Sunness","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0110","doi-asserted-by":"crossref","first-page":"304","DOI":"10.4274\/tjo.69260","article-title":"Fundus autofluorescence changes in age-related maculopathy","volume":"48","author":"Bingol K\u0131z\u0131ltun\u00e7","year":"2018","journal-title":"Turk. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0115","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.ophtha.2019.07.022","article-title":"Prevalence, risk, and genetic association of reticular pseudodrusen in age-related macular degeneration: age-related eye disease study 2 report 21","volume":"126","author":"Domalpally","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0120","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.ophtha.2015.10.029","article-title":"Reticular pseudodrusen and their association with age-related macular degeneration: the Melbourne Collaborative Cohort Study","volume":"123","author":"Finger","year":"2016","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0125","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1167\/iovs.12-11538","article-title":"Longitudinal analysis of reticular drusen associated with geographic atrophy in age related macular degeneration","volume":"54","author":"Steinberg","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0130","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1167\/iovs.12-11073","article-title":"Association between geographic atrophy progression and reticular pseudodrusen in eyes with dry age-related macular degeneration","volume":"54","author":"Marsiglia","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2020.102171_bib0135","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.ophtha.2015.12.026","article-title":"Incidence of age-related macular degeneration in a multi-ethnic United States population: the multi-ethnic study of atherosclerosis","volume":"123","author":"Fisher","year":"2016","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2020.102171_bib0140","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1167\/iovs.15-18593","article-title":"Distinct genetic risk profile of the rapidly progressing diffuse-trickling subtype of geographic atrophy in age-related macular degeneration","volume":"57","author":"Fleckenstein","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100020305251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100020305251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:41:17Z","timestamp":1761612077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100020305251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":28,"alternative-id":["S1572100020305251"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2020.102171","relation":{},"ISSN":["1572-1000"],"issn-type":[{"type":"print","value":"1572-1000"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of ocular and systemic risk factors on progression of geographic atrophy in age-related macular degeneration","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2020.102171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102171"}}