{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:00:36Z","timestamp":1789340436073,"version":"build-2803163510"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.pdpdt.2022.102883","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T12:05:23Z","timestamp":1650974723000},"page":"102883","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Determination of idiopathic female infertility from infrared spectra of follicle fluid combined with gonadotrophin levels, multivariate analysis and machine learning methods"],"prefix":"10.1016","volume":"38","author":[{"given":"Pawe\u0142","family":"Jakubczyk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wies\u0142aw","family":"Paja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Pancerz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozef","family":"Cebulski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Depciuch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zgur","family":"Uzun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevzat","family":"Tarhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4136-4447","authenticated-orcid":false,"given":"Zozan","family":"Guleken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pdpdt.2022.102883_bib0001","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1152\/physrev.00023.2015","article-title":"Physiological aspects of female fertility: role of the environment, modern lifestyle, and genetics","volume":"96","author":"Hart","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0002","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S1472-6483(10)61174-1","article-title":"Oxidative stress and its implications in female infertility - a clinician's perspective","volume":"11","author":"Agarwal","year":"2005","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0003","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.rbmo.2012.02.021","article-title":"Unexplained infertility: an update and review of practice","volume":"24","author":"Ray","year":"2012","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0004","first-page":"69","article-title":"Diagnosis and treatment of unexplained infertility","volume":"1","author":"Quaas","year":"2008","journal-title":"Rev. Obstet. Gynecol."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0005","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s10815-012-9861-4","article-title":"Assessment and treatment of repeated implantation failure (RIF)","volume":"29","author":"Simon","year":"2012","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0006","doi-asserted-by":"crossref","unstructured":"H. Ali \u0130nal, Z. \u00d6zt\u00fcrk \u0130nal, Early-cleavage versus blastocyst stage embryo transfer: a prospective comparative study, (2021). doi:10.4274\/jtgga.galenos.2021.2020.0171.","DOI":"10.4274\/jtgga.galenos.2021.2020.0171"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0007","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.bpobgyn.2018.09.006","article-title":"Unexplained infertility: is it over-diagnosed and over-treated?","volume":"53","author":"Mol","year":"2018","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0008","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1093\/humrep\/deg366","article-title":"Time to pregnancy: results of the German prospective study and impact on the management of infertility","volume":"18","author":"Gnoth","year":"2003","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0009","doi-asserted-by":"crossref","DOI":"10.1186\/s12610-019-0090-x","article-title":"Metabolic syndrome and smoking are independent risk factors of male idiopathic infertility","volume":"29","author":"Dupont","year":"2019","journal-title":"Basic Clin. Androl."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210770","article-title":"Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women","volume":"14","author":"Foucaut","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0011","doi-asserted-by":"crossref","DOI":"10.1093\/acrefore\/9780190632366.013.184","article-title":"Biological and social aspects of human infertility: a global perspective","author":"Thoma","year":"2021","journal-title":"Oxford Res. Encycl. Glob. Public Heal."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0012","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/humupd\/dml020","article-title":"Ovarian feedback, mechanism of action and possible clinical implications","volume":"12","author":"Messinisi","year":"2006","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0013","article-title":"The normal menstrual cycle and the control of ovulation","author":"Reed","year":"2000","journal-title":"Endotext"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.114250","article-title":"Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women","volume":"204","author":"Guleken","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0015","first-page":"2021","article-title":"Elevated serum level of DHEAS as a hormone and IL-6 as a proinflammatory cytokine may better indicate metabolic syndrome in PCOS women","volume":"71","author":"Guleken","year":"2021","journal-title":"J. Med. Physiol. Biophys."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120246","article-title":"Diagnosis of endometriosis using endometrioma volume and vibrational spectroscopy with multivariate methods as a noninvasive method","volume":"264","author":"Guleken","year":"2022","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0017","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.fertnstert.2009.04.010","article-title":"Follicular fluid steroid hormone levels are associated with fertilization outcome after intracytoplasmic sperm injection","volume":"94","author":"Lamb","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120684","article-title":"A novel diagnostic method: FT-IR, Raman and derivative spectroscopy fusion technology for the rapid diagnosis of renal cell carcinoma serum","volume":"269","author":"Chen","year":"2022","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2020.101792","article-title":"Raman spectroscopy combined with multiple algorithms for analysis and rapid screening of chronic renal failure","volume":"30","author":"Chen","year":"2020","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0020","article-title":"Urine Raman spectroscopy for rapid and inexpensive diagnosis of chronic renal failure (CRF) using multiple classification algorithms","volume":"203","author":"Chen","year":"2020","journal-title":"Optik (Stuttg)"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2020.101923","article-title":"Fourier transform infrared spectroscopy combined with deep learning and data enhancement for quick diagnosis of abnormal thyroid function","volume":"32","author":"Yue","year":"2020","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121006","article-title":"Differential of cholangiocarcinoma disease using Raman spectroscopy combined with multivariate analysis","volume":"272","author":"Depciuch","year":"2022","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122353","article-title":"Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer","volume":"231","author":"Guleken","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121119","article-title":"Correlation between endometriomas volume and Raman spectra. Attempting to use Raman spectroscopy in the diagnosis of endometrioma","author":"Guleken","year":"2022","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121029","article-title":"Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis","volume":"273","author":"Guleken","year":"2022","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.114250","article-title":"Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women","volume":"204","author":"Guleken","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.119639","article-title":"Spectrochemical and biochemical assay comparison study of the healing effect of the Aloe vera and Hypericum perforatum loaded nanofiber dressings on diabetic wound","volume":"254","author":"Guleken","year":"2021","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2022.102779","article-title":"Detection of the chemical changes in blood, liver, and brain caused by electromagnetic field exposure using Raman spectroscopy, biochemical assays combined with multivariate analyses","volume":"38","author":"Guleken","year":"2022","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0029","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1093\/humrep\/15.8.1667","article-title":"Fourier transform infrared spectroscopy of follicular fluids from large and small antral follicles","volume":"15","author":"Thomas","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113553","article-title":"Investigation of the discrimination and characterization of blood serum structure in patients with opioid use disorder using IR spectroscopy and PCA-LDA analysis","volume":"190","author":"Guleken","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122916","article-title":"Characterization of Covid-19 infected pregnant women sera using laboratory indexes, vibrational spectroscopy, and machine learning classifications","volume":"237","author":"Guleken","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.120189","article-title":"A rapid quality grade discrimination method for Gastrodia elata powderusing ATR-FTIR and chemometrics","volume":"264","author":"Zhan","year":"2022","journal-title":"Spectrochim. Acta - Part A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0033","first-page":"442","article-title":"BBA - Protein Struct","volume":"405","author":"Matthews","year":"1975"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0034","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.patrec.2005.10.010","article-title":"An introduction to ROC analysis","volume":"27","author":"Fawcett","year":"2006","journal-title":"Pattern Recognit. Lett."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0035","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach. Learn."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0036","first-page":"235","article-title":"C4.5: Programs for Machine Learning by J. Ross Quinlan. Morgan Kaufmann Publishers, Inc., 1993","volume":"16","author":"Salzberg","year":"1994","journal-title":"Mach. Learn."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0037","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/00031305.1992.10475879","article-title":"An introduction to kernel and nearest-neighbor nonparametric regression","volume":"46","author":"Altman","year":"1992","journal-title":"Am. Stat."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0038","series-title":"Deep Learning","author":"Goodfellow","year":"2016"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0039","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1142\/9789812796851_0014","article-title":"Statistical learning theory","author":"Zaknich","year":"2003","journal-title":"Neural Netw. Intell. Signal Process."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0040","series-title":"Proceedings of the 22nd ACM SIGKDD International Conference Knowl. Discovery and Data Mining","article-title":"XGBoost: a scalable tree boosting system","author":"Chen","year":"2022"},{"key":"10.1016\/j.pdpdt.2022.102883_bib0041","first-page":"11","article-title":"All relevant feature selection methods and applications","volume":"584","author":"Rudnicki","year":"2015","journal-title":"Stud. Comput. Intell."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0042","first-page":"1","article-title":"Infrared spectroscopy and microscopy in cancer research and diagnosis","volume":"2","author":"Bellisola","year":"2012","journal-title":"Am. J. Cancer Res."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0043","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/OGX.0000000000000043","article-title":"Definition and epidemiology of unexplained infertility","volume":"69","author":"Gelbaya","year":"2014","journal-title":"Obstet. Gynecol. Surv."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0044","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0015-0282(98)00177-0","article-title":"Efficacy of treatment for unexplained infertility","volume":"70","author":"Guzick","year":"1998","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0045","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0015-0282(00)00708-1","article-title":"Basal antral follicle number and mean ovarian diameter predict cycle cancellation and ovarian responsiveness in assisted reproductive technology cycles","volume":"74","author":"Frattarelli","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0046","doi-asserted-by":"crossref","first-page":"527","DOI":"10.5114\/aoms.2016.58843","article-title":"Decline in ovarian reserve may be an undiagnosed reason for unexplained infertility: a cohort study","volume":"14","author":"Y\u00fccel","year":"2018","journal-title":"Arch. Med. Sci."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0047","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1007\/s10815-012-9831-x","article-title":"The relationship between pregnancy and oxidative stress markers on patients undergoing ovarian stimulations","volume":"29","author":"Younis","year":"2012","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0048","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/molehr\/gas063","article-title":"The search for biomarkers of human embryo developmental potential in IVF: a comprehensive proteomic approach","volume":"19","author":"Nyalwidhe","year":"2013","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0049","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-020-01492-8","article-title":"Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: The disappearance of dimerization may indicate the change of protein conformation and even function","volume":"15","author":"Wang","year":"2020","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0050","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1007\/s10815-015-0592-1","article-title":"Lipidomics analysis of follicular fluid by ESI-MS reveals potential biomarkers for ovarian endometriosis","volume":"32","author":"Cordeiro","year":"2015","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2012.06.025","article-title":"Women with reduced ovarian reserve or advanced maternal age have an altered follicular environment","volume":"98","author":"Pacella","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0052","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.fertnstert.2012.02.034","article-title":"Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes","volume":"97","author":"Yang","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.pdpdt.2022.102883_bib0053","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049217","article-title":"High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation\/brain defects","volume":"7","author":"Luzzo","year":"2012","journal-title":"PLoS One"}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100022001697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100022001697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:46:05Z","timestamp":1761612365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100022001697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":53,"alternative-id":["S1572100022001697"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2022.102883","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of idiopathic female infertility from infrared spectra of follicle fluid combined with gonadotrophin levels, multivariate analysis and machine learning methods","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2022.102883","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102883"}}