{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T08:09:41Z","timestamp":1771574981322,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.pdpdt.2022.103012","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T18:55:40Z","timestamp":1657392940000},"page":"103012","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Choroidal structural evaluation in inactive Graves\u2019 ophthalmopathy"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8511-7504","authenticated-orcid":false,"given":"Kubra Serbest","family":"Ceylanoglu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazan Acar","family":"Eser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine Malkoc","family":"Sen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"16","key":"10.1016\/j.pdpdt.2022.103012_bib0001","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1056\/NEJMra1510030","article-title":"Graves' disease","volume":"375","author":"Smith","year":"2016","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.pdpdt.2022.103012_bib0002","article-title":"Thyroid-associated ophthalmopathy","volume":"47","author":"\u015eahl\u0131","year":"2017","journal-title":"Turk. J. Ophthalmol."},{"issue":"12","key":"10.1016\/j.pdpdt.2022.103012_bib0003","doi-asserted-by":"crossref","first-page":"6348","DOI":"10.4049\/jimmunol.170.12.6348","article-title":"Immunoglobulin activation of T cell chemoattractant expression in fibroblasts from patients with Graves' disease is mediated through the insulin-like growth factor I receptor pathway","volume":"170","author":"Pritchard","year":"2003","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.pdpdt.2022.103012_bib0004","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nrcardio.2016.174","article-title":"Thyroid hormones and cardiovascular disease","volume":"14","author":"Jabbar","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"issue":"2","key":"10.1016\/j.pdpdt.2022.103012_bib0005","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.cpcardiol.2015.04.002","article-title":"Thyroid disease and the heart","volume":"41","author":"Klein","year":"2016","journal-title":"Curr. Probl. Cardiol."},{"issue":"8","key":"10.1016\/j.pdpdt.2022.103012_bib0006","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/jcu.20154","article-title":"Graves' ophthalmopathy: comparison of the Doppler sonography parameters with the clinical activity score","volume":"33","author":"Yanik","year":"2005","journal-title":"J. Clin. Ultrasound."},{"issue":"9","key":"10.1016\/j.pdpdt.2022.103012_bib0007","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1136\/bjo.84.9.1027","article-title":"Colour Doppler imaging of the orbital vasculature in Graves' disease with computed tomographic correlation","volume":"84","author":"Alp","year":"2000","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0008","doi-asserted-by":"crossref","unstructured":"C.C. Tsai, H.C. Kau, S.C. Kao, M.W. Lin, W.M. Hsu, J.H. Liu, et\u00a0al., Pulsatile ocular blood flow in patients with Graves' ophthalmopathy, Eye (Lond). 19(2) (2005) 159\u201362. https:\/\/doi.org\/10.1038\/sj.eye.6701434.","DOI":"10.1038\/sj.eye.6701434"},{"issue":"11","key":"10.1016\/j.pdpdt.2022.103012_bib0009","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1080\/02713680701689773","article-title":"Increased retinal blood flow in patients with active Graves' ophthalmopathy","volume":"32","author":"Perri","year":"2007","journal-title":"Curr. Eye. Res."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0010","article-title":"The increment of Choroidal thickness in Euthyroid Graves' Ophthalmopathy: is it an early sign of venous congestion?","volume":"28","author":"Cagiltay","year":"2018","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0011","doi-asserted-by":"crossref","unstructured":"N. Yu, Y. Zhang, Analysis in choroidal thickness in patients with Graves' ophthalmopathy using spectral-domain optical coherence tomography, J. Ophthalmol. 2018 (2018) 3529395. https:\/\/doi.org\/10.1155\/2018\/3529395.","DOI":"10.1155\/2018\/3529395"},{"key":"10.1016\/j.pdpdt.2022.103012_bib0012","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","article-title":"The multifunctional choroid","volume":"29","author":"Nickla","year":"2010","journal-title":"Prog. Retin. Eye. Res."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0013","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1080\/02713683.2016.1198488","article-title":"Choroidal thickness in patients with Graves\u2019 ophthalmopathy","volume":"42","author":"Caliskan","year":"2017","journal-title":"Curr. Eye. Res."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0014","doi-asserted-by":"crossref","unstructured":"B. Ozkan, C.A. Kocer, O. Altintas, et\u00a0al., Choroidal changes observed with enhanced depth imaging optical coherence tomography in patients with mild Graves\u2019 orbitopathy, Eye (Lond). 30 (2016) 917\u201324. https:\/\/doi.org\/10.1038\/eye.2016.93.","DOI":"10.1038\/eye.2016.93"},{"key":"10.1016\/j.pdpdt.2022.103012_bib0015","doi-asserted-by":"crossref","first-page":"21090","DOI":"10.1038\/srep21090","article-title":"Choroidal vascularity index as a measure of vascular status of the choroid: measurements in healthy eyes from a population-based study","volume":"6","author":"Agrawal","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100829","article-title":"Exploring choroidal angioarchitecture in health and disease using choroidal vascu- larity index","volume":"77","author":"Agrawal","year":"2020","journal-title":"Prog. Retin. Eye. Res."},{"issue":"3","key":"10.1016\/j.pdpdt.2022.103012_bib0017","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1530\/EJE-07-0666","article-title":"Consensus statement of the European group on graves\u2019 orbitopathy (EUGOGO) on management of GO","volume":"158","author":"L.Bartalena","year":"2008","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0018","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1167\/iovs.11-8836","article-title":"Repeatability and reproducibility of subfoveal choroidal thickness in normal eyes of Japanese using different SD-OCT devices","volume":"1","author":"Yamashita","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"6","key":"10.1016\/j.pdpdt.2022.103012_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2015.03.005","article-title":"Luminal and stromal areas of choroid determined by binarization method of optical coherence tomographic images","volume":"159","author":"Sonoda","year":"2015","journal-title":"Am. J. Ophthalmol."},{"issue":"7","key":"10.1016\/j.pdpdt.2022.103012_bib0020","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/ceo.13525","article-title":"Choroidal thickness in thyroid-associated orbitopathy","volume":"47","author":"Lai","year":"2019","journal-title":"Clin. Exp. Ophthalmol."},{"issue":"5","key":"10.1016\/j.pdpdt.2022.103012_bib0021","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s00417-020-04616-9","article-title":"Evaluation of choroidal thickness and choroidal vascular blood flow in patients with thyroid-associated orbitopathy (TAO) using SD-OCT and Angio-OCT","volume":"258","author":"Del Noce","year":"2020","journal-title":"Graefes. Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0022","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/0301-4738.156976","article-title":"Investigation of the choroidal thickness in patients with hypothyroidism","volume":"63","author":"Ulas","year":"2015","journal-title":"Indian. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0023","doi-asserted-by":"crossref","first-page":"9555","DOI":"10.1167\/iovs.11-8076","article-title":"Choroidal thickness in healthy Chinese subjects","volume":"52","author":"Ding","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0024","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/02713683.2014.952828","article-title":"Effects of sex and age on the normal retinal and choroidal structures on optical coherence tomography","volume":"40","author":"Ooto","year":"2015","journal-title":"Curr. Eye. Res."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0025","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.ajo.2008.12.008","article-title":"A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes","volume":"147","author":"Margolis","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0026","article-title":"Evaluation of choroidal circulation and stromal features in Graves' disease","volume":"12","author":"Aksoy","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"issue":"1","key":"10.1016\/j.pdpdt.2022.103012_bib0027","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/01676830.2021.2014893","article-title":"Choroidal vascularity index in thyroid eye disease: comparison with controls and application in diagnosing non-inflammatory active disease","volume":"41","author":"Dave","year":"2022","journal-title":"Orbit"},{"key":"10.1016\/j.pdpdt.2022.103012_bib0028","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s40662-021-00242-6","article-title":"Choroidal vascularity index in thyroid-associated ophthalmopathy: a cross-sectional study","volume":"8","author":"Loiudice","year":"2021","journal-title":"Eye. Vis. (Lond)."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0029","article-title":"Choroidal vascularity index in thyroid-associated ophthalmopathy","volume":"26","author":"Yeter","year":"2021","journal-title":"Can. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0030","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ajo.2018.06.016","article-title":"Wide-field Choroidal Vascularity in Healthy Eyes","volume":"193","author":"Singh","year":"2018","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0031","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9452687","article-title":"Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid-Associated Ophthalmopathy And retinal nerve fiber layer measurements obtained by OCT in thyroid-associated ophthalmopathy","volume":"2016","author":"Sayin O","year":"2016","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0032","first-page":"277","article-title":"Retina and nerve fiber layer thickness in eyes with thyroid-associated ophthalmopathy","volume":"19","author":"Meirovitch","year":"2017","journal-title":"Isr. Med. Assoc. J."},{"key":"10.1016\/j.pdpdt.2022.103012_bib0033","article-title":"Retinal nerve fiber layer and ganglion cell complex thickness as a diagnostic tool in early stage dysthyroid optic neuropathy","volume":"7","author":"Lu","year":"2021","journal-title":"Eur. J. Ophthalmol."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100022002988?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100022002988?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:45:06Z","timestamp":1761612306000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100022002988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":33,"alternative-id":["S1572100022002988"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2022.103012","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Choroidal structural evaluation in inactive Graves\u2019 ophthalmopathy","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2022.103012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103012"}}