{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:24:05Z","timestamp":1774380245857,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.pdpdt.2025.104495","type":"journal-article","created":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T00:15:41Z","timestamp":1737764141000},"page":"104495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Evaluation of macula ganglion cell analysis and retinal nerve fiber layer thickness in preperimetric glaucoma, early stage glaucoma and healthy individuals"],"prefix":"10.1016","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9895-0650","authenticated-orcid":false,"given":"Ozlem","family":"AKTAS\u202f\u202fOZALTUN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozlem","family":"GURBUZ\u202f\u202fKOZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Alper","family":"YARANGUMELI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pdpdt.2025.104495_bib0001","unstructured":"World Health Organization. Blindness and visual impairment [Internet]. 2024 [cited 2024 Dec 29]. Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/blindness-and-visual-impairment."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104495_bib0002","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/bjo.86.2.238","article-title":"The definition and classification of glaucoma in prevalence surveys","volume":"86","author":"Foster","year":"2002","journal-title":"British J. Ophthalmol"},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104495_bib0003","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1038\/eye.2015.154","article-title":"Advances in retinal ganglion cell imaging","volume":"29","author":"Balendra","year":"2015","journal-title":"Eye"},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104495_bib0004","first-page":"1","article-title":"Primary open-angle glaucoma","volume":"2","author":"Weinreb","year":"2016","journal-title":"Nature Rev. Dis. Primers"},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104495_bib0005","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/cne.903000103","article-title":"Topography of ganglion cells in human retina","volume":"300","author":"Curcio","year":"1990","journal-title":"J. Compar. Neurol"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0006","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s10384-006-0433-y","article-title":"Measurement of retinal nerve fiber layer thickness and macular volume for glaucoma detection using optical coherence tomography","volume":"51","author":"Ojima","year":"2007","journal-title":"Jpn. J. Ophthalmol."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104495_bib0007","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1136\/bjophthalmol-2020-316296","article-title":"SD-OCT peripapillary nerve fibre layer and ganglion cell complex parameters in glaucoma: principal component analysis","volume":"105","author":"Pazos","year":"2021","journal-title":"British J. Ophthalmol"},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0008","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jcjo.2014.07.014","article-title":"Symptoms reported by patients with varying stages of glaucoma: rreview of 401 cases","volume":"49","author":"Lopez","year":"2014","journal-title":"Canad. J. Ophthalmol"},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0009","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/MAJ.0000000000000319","article-title":"What do patients with glaucoma see? Visual symptoms reported by patients with glaucoma","volume":"348","author":"Hu","year":"2014","journal-title":"Am. J. Med. Sci."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104495_bib0010","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.survophthal.2013.09.003","article-title":"Population-based glaucoma prevalence studies in Asians","volume":"59","author":"Cho","year":"2014","journal-title":"Surv. Ophthalmol."},{"issue":"15 Suppl","key":"10.1016\/j.pdpdt.2025.104495_bib0011","first-page":"S279","article-title":"Current therapeutic options and treatments in development for the management of primary open-angle glaucoma","volume":"23","author":"Liebmann","year":"2017","journal-title":"Am. J. Manage Care"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0012","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2174\/1874364100903010059","article-title":"Staging glaucoma patient: why and how?","volume":"3","author":"Susanna","year":"2009","journal-title":"Open. Ophthalmol. J."},{"issue":"12","key":"10.1016\/j.pdpdt.2025.104495_bib0013","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0188692","article-title":"Preperimetric Glaucoma Prospective Observational Study (PPGPS): ddesign, baseline characteristics, and therapeutic effect of tafluprost in preperimetric glaucoma eye","volume":"12","author":"Aizawa","year":"2017","journal-title":"PLoS. One"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0014","first-page":"13","article-title":"Diagnostic ability of macular nerve fiber layer thickness measured by swept-source optical coherence tomography in preperimetric glaucoma","volume":"12","author":"Yeha","year":"2024","journal-title":"Measurements"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0015","article-title":"Optical coherence tomography evaluation of peripapillary and macular structure changes in pre-perimetric glaucoma, early perimetric glaucoma, and ocular hypertension: a systematic review and meta-analysis","volume":"8","author":"Tong","year":"2021","journal-title":"Front. Med. (Lausanne)"},{"issue":"11","key":"10.1016\/j.pdpdt.2025.104495_bib0016","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.18240\/ijo.2022.11.08","article-title":"Diagnostic evaluation of optical coherence tomography parameters in normal, preperimetric and perimetric glaucoma patients","volume":"15","author":"Yusof","year":"2022","journal-title":"Int. J. Ophthalmol."},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104495_bib0017","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/IJG.0000000000000662","article-title":"Diagnostic ability of wide-field retinal nerve fiber layer maps using swept-source optical coherence tomography for detection of preperimetric and early perimetric glaucoma","volume":"26","author":"Lee","year":"2017","journal-title":"J. Glaucoma"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104495_bib0018","doi-asserted-by":"crossref","first-page":"231","DOI":"10.4103\/joco.joco_124_23","article-title":"The discriminatory ability of ganglion cell inner plexiform layer complex thickness in patients with preperimetric glaucoma","volume":"35","author":"Mehta","year":"2023","journal-title":"J. Curr. Ophthalmol."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104495_bib0019","doi-asserted-by":"crossref","first-page":"511","DOI":"10.4103\/ijo.IJO_1039_17","article-title":"Evaluation of macular ganglion cell analysis compared to retinal nerve fiber layer thickness for preperimetric glaucoma diagnosis","volume":"66","author":"Kaushik","year":"2018","journal-title":"Indian J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.104495_bib0020","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1583260","article-title":"Classification and statistical trend analysis in detecting glaucomatous visual field progression","author":"Valente","year":"2019","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.104495_bib0021","series-title":"Clinical Decisions in Glaucoma","author":"Hodapp","year":"1993"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0022","series-title":"The Glaucomas","article-title":"Principles of perimetry","author":"Lynn","year":"1996"},{"issue":"9","key":"10.1016\/j.pdpdt.2025.104495_bib0023","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1038\/s41433-018-0104-5","article-title":"Comparison of glaucoma-diagnostic ability between wide-field swept-source OCT retinal nerve fiber layer maps and spectral-domain OCT","volume":"32","author":"Lee","year":"2018","journal-title":"Eye"},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104495_bib0024","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/IJG.0b013e3181e079ed","article-title":"Evaluation of macular thickness and peripapillary retinal nerve fiber layer thickness for detection of early glaucoma using spectral domain optical coherence tomography","volume":"20","author":"Nakatani","year":"2011","journal-title":"J. Glaucoma"},{"issue":"9","key":"10.1016\/j.pdpdt.2025.104495_bib0025","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1097\/IJG.0b013e318259b2e1","article-title":"The applicability of ganglion cell complex parameters determined from SD-OCT images to detect glaucomatous eyes","volume":"22","author":"Arintawati","year":"2013","journal-title":"J. Glaucoma"},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104495_bib0026","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jcjo.2017.01.003","article-title":"Diagnostic accuracy of ganglion cell complex substructures in different stages of primary open-angle glaucoma","volume":"52","author":"Elbendary","year":"2017","journal-title":"Canad. J. Ophthalmol"},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0027","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.ophtha.2015.12.041","article-title":"Macular versus retinal nerve fiber layer parameters for diagnosing manifest glaucoma: a systematic review of diagnostic accuracy studies","volume":"123","author":"Oddone","year":"2016","journal-title":"Ophthalmology."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0125957","article-title":"Diagnostic ability of macular ganglion cell inner plexiform layer measurements in glaucoma using swept source and spectral domain optical coherence tomography","volume":"10","author":"Yang","year":"2015","journal-title":"PLoS. One"},{"issue":"9","key":"10.1016\/j.pdpdt.2025.104495_bib0029","doi-asserted-by":"crossref","first-page":"3214","DOI":"10.1167\/iovs.05-0294","article-title":"Comparative study of retinal nerve fiber layer measurement by StratusOCT and GDx VCC, I: correlation analysis in glaucoma","volume":"46","author":"Leung","year":"2005","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104495_bib0030","doi-asserted-by":"crossref","first-page":"e884","DOI":"10.1097\/IJG.0000000000000491","article-title":"Structure-functional parameters in differentiating between patients with different degrees of glaucoma","volume":"25","author":"Cennamo","year":"2016","journal-title":"J. Glaucoma"},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0031","first-page":"260","article-title":"Sensitivity and specificity of spectral OCT in patients with early glaucoma","volume":"75","author":"Bo\u010dkov\u00e1","year":"2019","journal-title":"Ceska a Slovenska Oftalmologie"},{"issue":"22","key":"10.1016\/j.pdpdt.2025.104495_bib0032","doi-asserted-by":"crossref","first-page":"6728","DOI":"10.3390\/jcm13226728","article-title":"The development and validation of a glaucoma health score for glaucoma screening based on clinical parameters and optical coherence tomography metrics","volume":"13","author":"Chaglasian","year":"2024","journal-title":"J. Clin. Med."},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104495_bib0033","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00401-016-1609-2","article-title":"Glaucoma: the retina and beyond","volume":"132","author":"Davis","year":"2016","journal-title":"Acta Neuropathol."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104495_bib0034","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.3390\/jcm13071966","article-title":"Current status and future perspectives of Optic nerve imaging in Glaucoma","volume":"13","author":"Lommatzsch","year":"2024","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.pdpdt.2025.104495_bib0035","article-title":"Extended ganglion cell layer thickness deviation maps with OCT in glaucoma diagnosis","volume":"8","author":"Lehmann","year":"2021","journal-title":"Front. Med. (Lausanne)"},{"key":"10.1016\/j.pdpdt.2025.104495_bib0036","article-title":"Applications of optical coherence tomography angiography in glaucoma: current status and future directions","volume":"11","author":"Shen","year":"2024","journal-title":"Front. Med. (Lausanne)"},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104495_bib0037","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.3390\/biomedicines12061211","article-title":"Unveiling novel structural biomarkers for the diagnosis of glaucoma","volume":"12","author":"Tsai","year":"2024","journal-title":"Biomedicines."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104495_bib0038","first-page":"4048","article-title":"Testing the performance and application of glaucoma risk score models on swept source optical coherence tomography data","volume":"65","author":"Kubota","year":"2024","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"8","key":"10.1016\/j.pdpdt.2025.104495_bib0039","doi-asserted-by":"crossref","DOI":"10.1167\/tvst.11.8.8","article-title":"Real-time risk score for glaucoma mass screening by spectral domain optical coherence tomography: development and validation","volume":"11","author":"Fukai","year":"2022","journal-title":"Transl. Vis. Sci. Technol."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0040","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/aos.12203","article-title":"Factors associated with lifetime risk of open-angle glaucoma blindness","volume":"92","author":"Peters","year":"2014","journal-title":"Acta Ophthalmol. (Copenh)"},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104495_bib0041","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.ophtha.2016.01.041","article-title":"Can automated imaging for optic disc and retinal nerve fiber layer analysis aid glaucoma detection?","volume":"123","author":"Banister","year":"2016","journal-title":"Ophthalmology."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104495_bib0042","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1167\/tvst.9.2.42","article-title":"A review of deep learning for screening, diagnosis, and detection of glaucoma progression","volume":"9","author":"Thompson","year":"2020","journal-title":"Transl. Vis. Sci. Technol."},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104495_bib0043","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.3390\/jpm14101062","article-title":"Artificial intelligence and advanced technology in glaucoma: a review","volume":"14","author":"Tonti","year":"2024","journal-title":"J. Pers. Med."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000250?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000250?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:47:42Z","timestamp":1744505262000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100025000250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":43,"alternative-id":["S1572100025000250"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104495","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of macula ganglion cell analysis and retinal nerve fiber layer thickness in preperimetric glaucoma, early stage glaucoma and healthy individuals","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104495","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104495"}}