{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T12:33:21Z","timestamp":1793536401146,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:00:00Z","timestamp":1738108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.pdpdt.2025.104507","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T22:34:35Z","timestamp":1738276475000},"page":"104507","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Use of Fourier transform infrared spectroscopy and chemometric analysis to predict the bacilloscopic index in the saliva of leprosy patients"],"prefix":"10.1016","volume":"52","author":[{"given":"Paulo Cezar","family":"de Moraes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L\u00facia","family":"Scroferneker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Koehler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia Maria","family":"Eidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiane Almeida Soares","family":"Cattani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8052-5354","authenticated-orcid":false,"given":"Valeriano Antonio","family":"Corbellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2019.12.080","article-title":"Leprosy: clinical aspects and diagnostic techniques","volume":"83","author":"Maymone","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0002","first-page":"61","article-title":"Hanseniasis","volume":"1","author":"Eidt","year":"2018"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0003","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3389\/fimmu.2018.00604","article-title":"Emerging concepts of adaptive immunity in leprosy","volume":"9","author":"Sadhu","year":"2018","journal-title":"Front. Immunol."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104507_bib0004","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/jdv.15569","article-title":"Position statement: LEPROSY: diagnosis, treatment and follow-up","volume":"33","author":"Alemu Belachew","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104507_bib0005","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1128\/CMR.19.2.338-381.2006","article-title":"The continuing challenges of leprosy","volume":"19","author":"Scollard","year":"2006","journal-title":"Clin. Microbiol. Rev."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0006","doi-asserted-by":"crossref","first-page":"181","DOI":"10.4103\/2141-9248.183936","article-title":"Utility of bacillary index in slit skin smears in correlation with clinical and histopathological alterations in Hansen's Disease: an attempt to revive a simple useful procedure","volume":"6","author":"Premalatha","year":"2016","journal-title":"Ann. Med. Health Sci. Res."},{"issue":"9","key":"10.1016\/j.pdpdt.2025.104507_bib0007","first-page":"e44767","article-title":"Leprosy classification, clinical features, epidemiology, and host immunological responses: failure of eradication in 2023","volume":"15","author":"Alrehaili","year":"2023","journal-title":"Cureus"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0008","first-page":"255","article-title":"Classification of leprosy according to immunity\u2014a five group system","volume":"34","author":"Ridley","year":"1966","journal-title":"Int. J. Lepr."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0009","doi-asserted-by":"crossref","first-page":"e189","DOI":"10.1016\/j.ijid.2012.10.003","article-title":"Evaluation of agreement between clinical and histopathological data for classifying leprosy","volume":"17","author":"Santos","year":"2013","journal-title":"Int. J. Infect. Dis."},{"issue":"Suppl 2","key":"10.1016\/j.pdpdt.2025.104507_bib0010","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1590\/S0037-86822008000700011","article-title":"Evaluation of the agreement between clinical and laboratorial exams in the diagnosis of leprosy","volume":"41","author":"Teixeira","year":"2008","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0011","doi-asserted-by":"crossref","first-page":"22","DOI":"10.33545\/pathol.2024.v7.i1a.551","article-title":"Histopathological spectrum of leprosy with clinicopathologic correlation","volume":"7","author":"Choudhary","year":"2024","journal-title":"Int. J. Clin. Diagn. Pathol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.841030","article-title":"Clinical, epidemiological, and laboratory prognostic factors in patients with leprosy reactions: a 10-year retrospective cohort study","volume":"9","author":"Antunes","year":"2022","journal-title":"Front. Med."},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104507_bib0013","first-page":"EC23","article-title":"Evaluation of fluorescent staining for diagnosis of leprosy and its impact on grading of the disease: comparison with conventional staining","volume":"10","author":"Adiga","year":"2016","journal-title":"J. Clin. Diagn. Res."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0014","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4103\/0019-5154.147791","article-title":"Comparison of bacillary index on slit skin smear with bacillary index of granuloma in leprosy and its relevance to present therapeutic regimens","volume":"60","author":"Kumaran","year":"2015","journal-title":"Indian J. Dermatol."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0015","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s40249-016-0203-0","article-title":"Can baseline ML flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil","volume":"5","author":"Hungria","year":"2016","journal-title":"Infect. Dis. Poverty"},{"issue":"22","key":"10.1016\/j.pdpdt.2025.104507_bib0016","first-page":"2083","article-title":"Challenges and advances in serological and molecular tests to aid leprosy diagnosis","volume":"248","author":"Lopes-Luz","year":"2023","journal-title":"Exp. Biol. Med."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104507_bib0017","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1590\/0074-0276130222","article-title":"Identification of clinical, epidemiological and laboratory risk factors for leprosy reactions during and after multidrug therapy","volume":"108","author":"Antunes","year":"2013","journal-title":"Mem. Inst. Oswaldo Cruz."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104507_bib0018","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1007\/s00253-016-7328-8","article-title":"Comparative evaluation of antibody detection tests to facilitate the diagnosis of multibacillary leprosy","volume":"100","author":"Duthie","year":"2016","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0019","series-title":"Guidelines For the diagnosis, treatment, and Prevention of Leprosy","year":"2018"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2022.103017","article-title":"Saliva may predict quality of life in psoriasis as measured by Fourier transform infrared spectroscopy (FTIR) and chemometrics","volume":"39","author":"da Silva","year":"2022","journal-title":"Photodiagnosis. Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124066","article-title":"Infrared spectroscopy combined with chemometrics in transflectance mode: an alternative approach in the photodiagnosis of COVID-19 using saliva","volume":"312","author":"Juchem","year":"2024","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.123048","article-title":"Raman spectroscopy and HT-XRD in compatibility study between naproxen and excipients","volume":"302","author":"Rojek","year":"2023","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124185","article-title":"FTIR spectroscopy for assessment of hair from lung cancer patients and its application in monitoring the chemotherapy treatment effect","volume":"314","author":"Zhu","year":"2024","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"issue":"11","key":"10.1016\/j.pdpdt.2025.104507_bib0024","doi-asserted-by":"crossref","DOI":"10.1002\/jbio.202300199","article-title":"Fiber optic probe-based ATR-FTIR spectroscopy for rapid breast cancer detection: a pilot study","volume":"16","author":"Zhang","year":"2023","journal-title":"J. Biophotonics"},{"issue":"12","key":"10.1016\/j.pdpdt.2025.104507_bib0025","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1016\/j.bbapap.2013.07.015","article-title":"Recent applications of ATR FTIR spectroscopy and imaging to proteins","volume":"1834","author":"Glassford","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123858","article-title":"Rapid and low-cost liquid biopsy with ATR-FTIR spectroscopy to discriminate the molecular subtypes of breast cancer","volume":"254","author":"Pereira de Souza","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.infrared.2020.103473","article-title":"Use of ATR-FTIR for detection of Salmonella typhi infection in human blood sera","volume":"110","author":"Naseer","year":"2020","journal-title":"Infrared. Phys. Technol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2022.115021","article-title":"Using infrared spectroscopy of serum and chemometrics for diagnosis of paracoccidioidomycosis","volume":"221","author":"Koehler","year":"2022","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0029","series-title":"Pirouette Multivariate Data Analysis Software, Version 5","year":"2023"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0030","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0731-7085(02)00401-6","article-title":"An evaluation of direct orthogonal signal correction and other preprocessing methods for the classification of clinical study lots of a dermatological cream","volume":"30","author":"Luypaert","year":"2002","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0031","series-title":"American Society for Testing and Materials. Standard Practices For Infrared Multivariate Quantitative Analysis","year":"2017"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0032","doi-asserted-by":"crossref","first-page":"237","DOI":"10.3390\/nano14030237","article-title":"Assessing phytogenic and chemogenic silver nanoparticles for antibacterial activity and expedited wound recuperation","volume":"14","author":"Ahmad","year":"2024","journal-title":"Nanomaterials"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0033","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1111\/jam.14171","article-title":"Rapid tool for identification of bacterial strains using Fourier transform infrared spectroscopy on genomic DNA","volume":"126","author":"Lee","year":"2019","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0034","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0169-7439(98)00109-9","article-title":"Orthogonal signal correction of near-infrared spectra","volume":"44","author":"Wold","year":"1998","journal-title":"Chemometr. Intell. Lab. Syst."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0035","first-page":"255","article-title":"Four-year follow-up results of a WHO-recommended multiple-drug regimen in paucibacillary leprosy patients in Malawi","volume":"59","author":"Boerrigter","year":"1991","journal-title":"Int. J. Lepr. Other Mycobact. Dis."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104507_bib0036","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1080\/08830185.2020.1851370","article-title":"Immunology of leprosy","volume":"41","author":"Froes","year":"2022","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0037","series-title":"Hansen\u00edase: Avan\u00e7os e Desafios","article-title":"Diagn\u00f3stico e tratamento da hansen\u00edase","author":"Lyon","year":"2014"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0038","series-title":"Protocolo Cl\u00ednico e Diretrizes Terap\u00eauticas Da Hansen\u00edase","year":"2022"},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104507_bib0039","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1093\/qjmed\/hcad056","article-title":"Leprosy and broken bacilli on slit skin smear","volume":"116","author":"Sukanya","year":"2023","journal-title":"QJM: Int. J. Med."},{"issue":"12","key":"10.1016\/j.pdpdt.2025.104507_bib0040","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1017\/S0031182023000422","article-title":"Neglected Tropical Diseases in Italy: introducing IN-NTD, the Italian network for NTDs","volume":"150","author":"Casulli","year":"2023","journal-title":"Parasitology"},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0041","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jaad.2019.10.138","article-title":"Leprosy: treatment and management of complications","volume":"83","author":"Maymone","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104507_bib0042","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1080\/05704928.2020.1738453","article-title":"ATR-FTIR spectroscopy as the future of diagnostics: a systematic review of the approach using bio-fluids","volume":"56","author":"Naseer","year":"2020","journal-title":"Appl. Spectrosc. Rev."},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104507_bib0043","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/0003702820985856","article-title":"Infrared spectroscopy of blood","volume":"75","author":"Kochan","year":"2021","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2021.119647","article-title":"Rapid classification of chromoblastomycosis agents genera by infrared spectroscopy and chemometrics supervised by sequencing of rDNA regions","volume":"254","author":"Heidrich","year":"2021","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"issue":"14","key":"10.1016\/j.pdpdt.2025.104507_bib0045","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1039\/c2an16300d","article-title":"Extracting biological information with computational analysis of fourier-transform infrared (FTIR) biospectroscopy datasets: current practices to future perspectives","volume":"137","author":"Trevisan","year":"2012","journal-title":"Analyst"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0046","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.136055","article-title":"A methodological approach to preprocessing FTIR spectra of adulterated sesame oil","volume":"419","author":"Khodabakhshian","year":"2023","journal-title":"Food Chem."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104507_bib0047","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s00216-005-3148-x","article-title":"Orthogonal signal correction applied to the classification of wine and molasses vinegar samples by near-infrared spectroscopy. Feasibility study for the detection and quantification of adulterated vinegar samples","volume":"382","author":"S\u00e1iz-Abajo","year":"2005","journal-title":"Anal. Bioanal. Chem."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104507_bib0048","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.saa.2007.06.017","article-title":"Orthogonal signal correction-partial least squares method for simultaneous spectrophotometric determination of cypermethrin and tetramethrin","volume":"69","author":"Niazi","year":"2008","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0049","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1471-230X-14-115","article-title":"1HNMR-based metabolomic profile of rats with experimental acute pancreatitis","volume":"14","author":"Li","year":"2014","journal-title":"BMC Gastroenterol."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104507_bib0050","first-page":"177","article-title":"Slit-skin smear in leprosy: lest we forget it!","volume":"85","author":"Mahajan","year":"2013","journal-title":"Indian J. Lepr."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0051","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3390\/jpm13060907","article-title":"Unlocking the diagnostic potential of saliva: a comprehensive review of infrared spectroscopy and its applications in salivary analysis","volume":"13","author":"Delrue","year":"2023","journal-title":"J. Pers. Med."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0052","article-title":"Biochemical composition and characteristics of salivary FTIR spectra: correlation analysis","volume":"341","author":"LV","year":"2021","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0053","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.vibspec.2018.08.019","article-title":"Enabling quantification of protein concentration in human serum biopsies using attenuated total reflectance\u2013Fourier transform infrared (ATR-FTIR) spectroscopy","volume":"99","author":"Spalding","year":"2018","journal-title":"Vib. Spectrosc."},{"issue":"3\u20134","key":"10.1016\/j.pdpdt.2025.104507_bib0054","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/jbio.201300167","article-title":"Assessing the challenges of Fourier transform infrared spectroscopic analysis of blood serum","volume":"7","author":"Hughes","year":"2014","journal-title":"J. Biophotonics."},{"issue":"28","key":"10.1016\/j.pdpdt.2025.104507_bib0055","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1039\/C8AY00862K","article-title":"ATR-FTIR spectroscopy with equidistant combination PLS method applied for rapid determination of glycated hemoglobin","volume":"10","author":"Han","year":"2018","journal-title":"Anal. Methods"},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0056","first-page":"90","article-title":"Quantitation of urea in urine by Fourier transforms infrared spectroscopy","volume":"6","author":"Ahmad","year":"2014","journal-title":"Der Pharma Chemica"},{"issue":"13\u201314","key":"10.1016\/j.pdpdt.2025.104507_bib0057","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.clinbiochem.2014.05.064","article-title":"Simultaneous determination of glucose, triglycerides, urea, cholesterol, albumin and total protein in human plasma by Fourier transform infrared spectroscopy: direct clinical biochemistry without reagents","volume":"47","author":"Jessen","year":"2014","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0058","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.microc.2012.06.016","article-title":"Evaluation of infrared spectroscopy as a screening tool for serum analysis: impact of the nature of samples included in the calibration set","volume":"106","author":"Perez-Guaita","year":"2013","journal-title":"Microchem. J."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104507_bib0059","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1590\/S0074-02762013000500006","article-title":"Detection of mycobacterium leprae in saliva and the evaluation of oral sensitivity in patients with leprosy","volume":"108","author":"Rosa","year":"2013","journal-title":"Mem. Inst. Oswaldo Cruz."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0060","article-title":"Saliva as a reliable, non-invasive specimen for detecting and monitoring mycobacterium leprae","author":"Yang","year":"2024","journal-title":"Lancet Microbe"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0061","first-page":"343","article-title":"Salivary immunoglobulins and antibody activities in leprosy","volume":"52","author":"Abe","year":"1984","journal-title":"Int. J. Lepr. Other Mycobact. Dis."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104507_bib0062","first-page":"225","article-title":"Immunoglobulin class specific antibodies to M. leprae in leprosy patients, including the indeterminate group and healthy contacts as a step in the development of methods for sero-diagnosis of leprosy","volume":"47","author":"Melsom","year":"1982","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0063","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.abd.2021.08.006","article-title":"Leprosy: clinical and immunopathological characteristics","volume":"97","author":"Junior","year":"2022","journal-title":"An. Bras. Dermatol."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0064","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.bi.64.070195.000333","article-title":"The envelope of mycobacteria","volume":"64","author":"Brennan","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.pdpdt.2025.104507_bib0065","first-page":"131","article-title":"Infrared spectroscopy in microbiology","volume":"102","author":"Naumann","year":"2000","journal-title":"Encyclopedia Anal. Chem."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0066","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1128\/IAI.74.1.175-182.2006","article-title":"Antigen discovery: a postgenomic approach to leprosy diagnosis","volume":"74","author":"Ar\u00e1oz","year":"2006","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104507_bib0067","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/proteomes9010007","article-title":"Insights sobre a prote\u00f4mica e biomarcadores do Mycobacterium leprae \u2014 uma vis\u00e3o geral","volume":"9","author":"Gautam","year":"2021","journal-title":"Proteomas"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0068","doi-asserted-by":"crossref","DOI":"10.1016\/j.bspc.2022.103525","article-title":"FT-IR saliva analysis for the diagnosis of psoriasis: a pilot study","volume":"74","author":"Pullano","year":"2022","journal-title":"Biomed. Signal. Process. Control"},{"key":"10.1016\/j.pdpdt.2025.104507_bib0069","unstructured":"Minist\u00e9rio da Sa\u00fade Secretaria de Vigil\u00e2ncia em sa\u00fade e Ambiente. Boletim Epidemiol\u00f3gico Hansen\u00edase 2024. https:\/\/www.gov.br\/saude\/pt-br\/centrais-de-conteudo\/publicacoes\/boletins\/epidemiologicos\/especiais\/2024\/be_hansen-2024_19jan_final.pdf, 2024 (accessed 04 August 2024)."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104507_bib0070","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1590\/S0037-86822010000300015","article-title":"Caracter\u00edsticas epidemiol\u00f3gicas e cl\u00ednicas das rea\u00e7\u00f5es hans\u00eanicas em indiv\u00edduos paucibacilares e multibacilares, atendidos em dois centros de refer\u00eancia para hansen\u00edase, na Cidade de Recife, Estado de Pernambuco","volume":"43","author":"Teixeira","year":"2010","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104507_bib0071","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.abd.2022.08.009","article-title":"Epidemiological characteristics of leprosy from 2000 to 2019 in a state with low endemicity in southern Brazil","volume":"98","author":"Moraes","year":"2023","journal-title":"An. Bras. Dermatol."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T23:14:26Z","timestamp":1744499666000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100025000377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":71,"alternative-id":["S1572100025000377"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104507","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of Fourier transform infrared spectroscopy and chemometric analysis to predict the bacilloscopic index in the saliva of leprosy patients","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104507","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104507"}}