{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:08:40Z","timestamp":1789549720401,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.pdpdt.2025.104556","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T04:20:32Z","timestamp":1741839632000},"page":"104556","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Performance of Raman Spectroscopy in biopsy tissue for rapid diagnosis of Tracheobronchial Tuberculosis: A prospective study"],"prefix":"10.1016","volume":"53","author":[{"given":"Qin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingming","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuexiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghui","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine Lin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.pdpdt.2025.104556_bib0001","doi-asserted-by":"crossref","first-page":"3818","DOI":"10.21037\/jtd.2016.12.75","article-title":"Tracheobronchial tuberculosis","volume":"8","author":"Pathak","year":"2016","journal-title":"J. Thorac. Dis."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104556_bib0002","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1378\/chest.09-1846","article-title":"CT scan features as predictors of patient outcome after bronchial intervention in endobronchial TB","volume":"138","author":"Lee","year":"2010","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104556_bib0003","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000492335","article-title":"Incidence and predictors of tracheobronchial tuberculosis in pulmonary tuberculosis: a multicentre, large-scale and prospective study in southern China","volume":"97","author":"Su","year":"2019","journal-title":"Respiration."},{"issue":"8","key":"10.1016\/j.pdpdt.2025.104556_bib0004","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0237753","article-title":"The epidemiology of extrapulmonary tuberculosis in China: a large-scale multi-center observational study","volume":"15","author":"Kang","year":"2020","journal-title":"PLoS. One"},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104556_bib0005","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/resp.12474","article-title":"Incidence and clinical predictors of endobronchial tuberculosis in patients with pulmonary tuberculosis","volume":"20","author":"Jung","year":"2015","journal-title":"Respirology."},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104556_bib0006","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3892\/etm.2020.9304","article-title":"Incidence, laboratory diagnosis and predictors of tracheobronchial tuberculosis in patients with pulmonary tuberculosis in Chongqing, China","volume":"20","author":"Peng","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0007","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/594806","article-title":"Challenges in endobronchial tuberculosis: from diagnosis to management","volume":"2014","author":"Kashyap","year":"2014","journal-title":"Pulm. Med."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104556_bib0008","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1378\/chest.102.4.990","article-title":"Endobronchial tuberculosis. Clinical and bronchoscopic features in 121 cases","volume":"102","author":"Lee","year":"1992","journal-title":"Chest"},{"issue":"12","key":"10.1016\/j.pdpdt.2025.104556_bib0009","first-page":"1163","article-title":"A comprehensive comparison of Ziehl-Neelsen and fluorescence microscopy for the diagnosis of tuberculosis in a resource-poor urban setting","volume":"7","author":"Kivihya-Ndugga","year":"2003","journal-title":"Int. J. Tuberc. Lung Dis."},{"issue":"515","key":"10.1016\/j.pdpdt.2025.104556_bib0010","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaw8287","article-title":"A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough","volume":"11","author":"Ahmad","year":"2019","journal-title":"Sci. Transl. Med."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104556_bib0011","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S1473-3099(18)30613-3","article-title":"Clinical utility of existing and second-generation interferon-\u03b3 release assays for diagnostic evaluation of tuberculosis: an observational cohort study","volume":"19","author":"Whitworth","year":"2019","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0012","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.mimet.2015.11.016","article-title":"Serodiagnostic potential of immuno-PCR using a cocktail of mycobacterial antigen 85B, ESAT-6 and cord factor in tuberculosis patients","volume":"120","author":"Singh","year":"2016","journal-title":"J. Microbiol. Methods"},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104556_bib0013","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1111\/resp.13316","article-title":"GeneXpert MTB\/RIF for rapid diagnosis and rifampin resistance detection of endobronchial tuberculosis","volume":"23","author":"Zhang","year":"2018","journal-title":"Respirology."},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104556_bib0014","doi-asserted-by":"crossref","DOI":"10.1177\/0300060520921640","article-title":"Performance of the Xpert\u00ae MTB\/RIF assay in the rapid diagnosis of tracheobronchial tuberculosis using bronchial washing fluid","volume":"48","author":"Song","year":"2020","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0015","article-title":"Diagnostic efficacy of Xpert MTB\/RIF assay in bronchoalveolar lavage fluid for tracheobronchial tuberculosis: a retrospective analysis","volume":"8","author":"Sun","year":"2021","journal-title":"Front. Med. (Lausanne)"},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104556_bib0016","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/09273948.2019.1655581","article-title":"The emerging challenge of diagnosing drug-resistant tubercular uveitis: experience of 110 eyes from North India","volume":"29","author":"Sharma","year":"2021","journal-title":"Ocul. Immunol. Inflamm."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104556_bib0017","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1364\/BOE.10.003533","article-title":"Identifying non-muscle-invasive and muscle-invasive bladder cancer based on blood serum surface-enhanced Raman spectroscopy","volume":"10","author":"Chen","year":"2019","journal-title":"Biomed. Opt. Express."},{"issue":"7","key":"10.1016\/j.pdpdt.2025.104556_bib0018","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1039\/C5CS00466G","article-title":"Development of deep subsurface Raman spectroscopy for medical diagnosis and disease monitoring","volume":"45","author":"Matousek","year":"2016","journal-title":"Chem. Soc. Rev."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104556_bib0019","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s10555-018-9770-9","article-title":"Applications of Raman spectroscopy in cancer diagnosis","volume":"37","author":"Auner","year":"2018","journal-title":"Cancer Metastasis Rev."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104556_bib0020","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1021\/acschemneuro.7b00413","article-title":"An emerging tool in neurodegenerative disease research and diagnosis","volume":"9","author":"Devitt","year":"2018","journal-title":"ACS. Chem. Neurosci."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0021","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.pdpdt.2018.10.014","article-title":"Analysis of tuberculosis disease through Raman spectroscopy and machine learning","volume":"24","author":"Khan","year":"2018","journal-title":"Photodiagnosis. Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.tube.2022.102251","article-title":"Raman spectroscopy and machine learning-based optical probe for tuberculosis diagnosis via sputum","volume":"136","author":"Ullah","year":"2022","journal-title":"Tuberculosis. (Edinb)"},{"issue":"2","key":"10.1016\/j.pdpdt.2025.104556_bib0023","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1378\/chest.117.2.385","article-title":"Bronchoscopic assessment of the evolution of endobronchial tuberculosis","volume":"117","author":"Chung","year":"2000","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.pdpdt.2025.104556_bib0024","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2478\/jtim-2022-0059","article-title":"Antibiotic stewardship: dead bugs do not mutate","volume":"10","author":"Martin-Loeches","year":"2022","journal-title":"J. Transl. Int. Med."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104556_bib0025","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1515\/jtim-2017-0030","article-title":"Bronchial wash gene xpert MTB\/RIF in lower lung field tuberculosis: sensitive, superior, and rapid in comparison with conventional diagnostic techniques","volume":"5","author":"Patil","year":"2017","journal-title":"J. Transl. Int. Med."},{"issue":"10","key":"10.1016\/j.pdpdt.2025.104556_bib0026","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1111\/resp.13316","article-title":"GeneXpert MTB\/RIF for rapid diagnosis and rifampin resistance detection of endobronchial tuberculosis","volume":"23","author":"Zhang","year":"2018","journal-title":"Respirology."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0027","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.saa.2019.04.055","article-title":"Raman spectroscopic discrimination of normal and cancerous lung tissues","volume":"219","author":"Sinica","year":"2019","journal-title":"Spectrochim. Acta a Mol. Biomol. Spectrosc."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104556_bib0028","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1080\/05704920701551530","article-title":"Raman spectroscopy of biological tissues","volume":"42","author":"Movasaghi Z","year":"2007","journal-title":"Appl. Spectrosc. Rev."},{"issue":"13","key":"10.1016\/j.pdpdt.2025.104556_bib0029","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1056\/NEJMoa1213261","article-title":"Analysis of circulating tumor DNA to monitor metastatic breast cancer","volume":"368","author":"Dawson","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.pdpdt.2025.104556_bib0030","doi-asserted-by":"crossref","first-page":"4977","DOI":"10.2147\/IJN.S167996","article-title":"Surface-enhanced Raman spectroscopy of blood serum based on gold nanoparticles for tumor stages detection and histologic grades classification of oral squamous cell carcinoma","volume":"13","author":"Xue","year":"2018","journal-title":"Int. J. Nanomedicine"},{"issue":"224","key":"10.1016\/j.pdpdt.2025.104556_bib0031","doi-asserted-by":"crossref","first-page":"224ra24","DOI":"10.1126\/scitranslmed.3007094","article-title":"Detection of circulating tumor DNA in early- and late-stage human malignancies","volume":"6","author":"Bettegowda","year":"2014","journal-title":"Sci. Transl. Med."},{"issue":"15","key":"10.1016\/j.pdpdt.2025.104556_bib0032","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1111\/j.1742-4658.2012.08651.x","article-title":"Normal and cancer cell metabolism: lymphocytes and lymphoma","volume":"279","author":"Altman","year":"2012","journal-title":"FEBS. J."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.104556_bib0033","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF00225648","article-title":"The metabolic environment of cancer","volume":"81","author":"Argil\u00e9s","year":"1988","journal-title":"Mol. Cell Biochem."},{"issue":"11","key":"10.1016\/j.pdpdt.2025.104556_bib0034","doi-asserted-by":"crossref","first-page":"4918","DOI":"10.1158\/0008-5472.CAN-08-4806","article-title":"Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry","volume":"69","author":"Hirayama","year":"2009","journal-title":"Cancer Res."},{"issue":"3","key":"10.1016\/j.pdpdt.2025.104556_bib0035","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.mad.2003.12.003","article-title":"Autophagy and aging\u2013importance of amino acid levels","volume":"125","author":"Dr\u00f6ge","year":"2004","journal-title":"Mech. Ageing Dev."},{"issue":"23","key":"10.1016\/j.pdpdt.2025.104556_bib0036","doi-asserted-by":"crossref","first-page":"15171","DOI":"10.1021\/acs.analchem.9b03960","article-title":"Revealing the metabolic activity of persisters in mycobacteria by single-cell D2O raman imaging spectroscopy","volume":"91","author":"Ueno","year":"2019","journal-title":"Anal. Chem."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025000857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T05:24:14Z","timestamp":1760073854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100025000857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":36,"alternative-id":["S1572100025000857"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104556","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Performance of Raman Spectroscopy in biopsy tissue for rapid diagnosis of Tracheobronchial Tuberculosis: A prospective study","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104556","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104556"}}