{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:39:23Z","timestamp":1786995563547,"version":"build-2736575974"},"reference-count":6,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013105","name":"Shanghai Rising-Star Program","doi-asserted-by":"publisher","award":["24QA2702500"],"award-info":[{"award-number":["24QA2702500"]}],"id":[{"id":"10.13039\/501100013105","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007279","name":"Shanghai Municipal Health Bureau","doi-asserted-by":"publisher","award":["202362"],"award-info":[{"award-number":["202362"]}],"id":[{"id":"10.13039\/501100007279","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003347","name":"Fudan University","doi-asserted-by":"publisher","award":["XXRC2214"],"award-info":[{"award-number":["XXRC2214"]}],"id":[{"id":"10.13039\/501100003347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82374204"],"award-info":[{"award-number":["82374204"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["2022YQ059"],"award-info":[{"award-number":["2022YQ059"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.pdpdt.2025.104624","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T17:28:29Z","timestamp":1746725309000},"page":"104624","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Raman spectroscopy assisted diagnosis and photodynamic therapy efficacy evaluation of actinic keratosis: Case report"],"prefix":"10.1016","volume":"53","author":[{"given":"Rongyi","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongjun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8076-9578","authenticated-orcid":false,"given":"Minfeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.pdpdt.2025.104624_bib0001","doi-asserted-by":"crossref","first-page":"e209","DOI":"10.1016\/j.jaad.2021.02.082","article-title":"Guidelines of care for the management of actinic keratosis","volume":"85","author":"Eisen","year":"2021","journal-title":"J. Am. Acad. Dermatol."},{"issue":"5","key":"10.1016\/j.pdpdt.2025.104624_bib0002","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.7150\/thno.92621","article-title":"Cancer diagnosis using label-free SERS-based exosome analysis","volume":"14","author":"Liu","year":"2024","journal-title":"Theranostics"},{"key":"10.1016\/j.pdpdt.2025.104624_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.127283","article-title":"Raman spectroscopy for cell analysis: retrospect and prospect","volume":"285","author":"Xu","year":"2025","journal-title":"Talanta"},{"issue":"11","key":"10.1016\/j.pdpdt.2025.104624_bib0004","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1002\/bip.21037","article-title":"The molecular structure and physical properties of elastin fibers as revealed by Raman microspectroscopy","volume":"89","author":"Green","year":"2008","journal-title":"Biopolymers"},{"issue":"6","key":"10.1016\/j.pdpdt.2025.104624_bib0005","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1038\/sj.jid.5700647","article-title":"Accumulation of elafin in actinic elastosis of sun-damaged skin: elafin binds to elastin and prevents elastolytic degradation","volume":"127","author":"Muto","year":"2007","journal-title":"J. Invest. Dermatol."},{"issue":"11","key":"10.1016\/j.pdpdt.2025.104624_bib0006","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1177\/00037028221101634","article-title":"Raman spectroscopy study of skin biopsies from patients with Parkinson's Disease: trends in alpha-synuclein aggregation from the Amide I region","volume":"76","author":"Leon-Bejarano","year":"2022","journal-title":"Appl. Spectrosc."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025001565?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025001565?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T05:30:13Z","timestamp":1760074213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100025001565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":6,"alternative-id":["S1572100025001565"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104624","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Raman spectroscopy assisted diagnosis and photodynamic therapy efficacy evaluation of actinic keratosis: Case report","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.104624","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"104624"}}