{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:12:40Z","timestamp":1789690360272,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002402","name":"Sun Yat-sen University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020084","name":"Guangzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["2021\\u201302\\u201301\\u201304\\u20130203"],"award-info":[{"award-number":["2021\\u201302\\u201301\\u201304\\u20130203"]}],"id":[{"id":"10.13039\/501100020084","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.pdpdt.2025.105287","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T15:14:57Z","timestamp":1763651697000},"page":"105287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Analysis of colour defects and microvascular abnormalities in dysthyroid optic neuropathy using optical coherence tomography angiography"],"prefix":"10.1016","volume":"56","author":[{"given":"Jiaqi","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuxian","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingtong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6605-4736","authenticated-orcid":false,"given":"Peng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pdpdt.2025.105287_bib0001","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/S0161-6420(88)32978-7","article-title":"Dysthyroid optic neuropathy. The crowded orbital apex syndrome","volume":"95","author":"Neigel","year":"1988","journal-title":"Ophthalmology"},{"key":"10.1016\/j.pdpdt.2025.105287_bib0002","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/112067211002000226","article-title":"Visual neuropraxia and progressive vision loss from thyroid-associated stretch optic neuropathy","volume":"20","author":"Soni","year":"2010","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0003","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1115\/1.1324667","article-title":"Tissue-level thresholds for axonal damage in an experimental model of Central nervous system white matter injury","volume":"122","author":"Bain","year":"2000","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0004","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1089\/089771501300227305","article-title":"Dynamic stretch correlates to both morphological abnormalities and electrophysiological impairment in a model of traumatic axonal injury","volume":"18","author":"Bain","year":"2001","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.pdpdt.2025.105287_bib0005","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1038\/s41433-024-02967-9","article-title":"The changing landscape of thyroid eye disease: current clinical advances and future outlook","volume":"38","author":"Moledina","year":"2024","journal-title":"Eye (L.)"},{"key":"10.1016\/j.pdpdt.2025.105287_bib0006","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.survophthal.2023.11.009","article-title":"Diagnostic methods for dysthyroid optic neuropathy: a systematic review and analysis","volume":"69","author":"Sio","year":"2024","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0007","article-title":"Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) for assessing thyroid-associated ophthalmopathy activity","volume":"53","author":"Huihui","year":"2025","journal-title":"Photodiagnosis. Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0008","first-page":"43","article-title":"Automated evaluation of parapapillary choroidal microvasculature in thyroid eye disease","author":"Hidayet","year":"2023","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0009","article-title":"Comprehensive visualization of choroidal alterations in thyroid eye disease with ultra-widefield OCT angiography","volume":"66","author":"Yi","year":"2025","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0010","article-title":"A window to the brain-the enduring impact of vision research","volume":"15","author":"George","year":"2025","journal-title":"Brain Sci."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0011","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1159\/000443828","article-title":"The 2016 European Thyroid Association\/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' Orbitopathy","volume":"5","author":"Bartalena","year":"2016","journal-title":"Eur. Thyroid. J."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0012","first-page":"261","article-title":"A diagnostic model based on color vision examination for dysthyroid optic neuropathy using Hardy-Rand-Rittler color plates","author":"Jiaqi","year":"2023","journal-title":"Graefe's Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0013","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00417-012-2073-x","article-title":"Comparison between Hardy-Rand-Rittler 4th edition and Ishihara color plate tests for detection of dyschromatopsia in optic neuropathy","volume":"251","author":"Huna-Baron","year":"2013","journal-title":"Graefe's Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0014","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1016\/j.ophtha.2015.06.013","article-title":"Ability of bottle cap color to facilitate accurate patient-physician communication regarding medication identity in patients with glaucoma","volume":"122","author":"P","year":"2015","journal-title":"Ophthalmology."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0015","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/17469899.2017.1276444","article-title":"Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management","volume":"12","author":"Blandford","year":"2017","journal-title":"Expert. Rev. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0016","unstructured":"Henry B.B., Petros P., Tomasz B., David S.C., Peter J.D., Angela M.L., Ilse M., Mario S., Marius N.S.JT. Management of thyroid eye disease: a consensus statement by the american thyroid association and the european thyroid association. 2022; 32."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0017","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1136\/bjo.2006.094607","article-title":"Clinical features of dysthyroid optic neuropathy: a European Group on Graves' Orbitopathy (EUGOGO) survey","volume":"91","author":"McKeag","year":"2007","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0018","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11082068","article-title":"Dysthyroid optic neuropathy: treatment with additional intravenous methylprednisolone pulses after the basic schedule is associated with stabilization or further improvement of clinical outcome","volume":"11","author":"Pelewicz","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0019","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/01.IOP.0000083645.19368.99","article-title":"Transcaruncular orbital decompression for dysthyroid optic neuropathy","volume":"19","author":"Perry","year":"2003","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0020","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1089\/thy.2013.0445","article-title":"Therapeutic outcomes of high-dose intravenous steroids in the treatment of dysthyroid optic neuropathy","volume":"24","author":"Curr\u00f2","year":"2014","journal-title":"Thyroid"},{"key":"10.1016\/j.pdpdt.2025.105287_bib0021","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jcjo.2013.10.006","article-title":"Optic neuropathy in thyroid eye disease: results of the balanced decompression technique","volume":"49","author":"Baril","year":"2014","journal-title":"Can. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0022","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.ajo.2010.11.001","article-title":"Predictability of visual function and nerve fiber layer thickness by cross-sectional areas of extraocular muscles in graves ophthalmopathy","volume":"151","author":"Wei","year":"2011","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00041327-199703000-00001","article-title":"Evaluation of a significantly shorter version of the Farnsworth-Munsell 100-hue test in patients with three different optic neuropathies","volume":"17","author":"Nichols","year":"1997","journal-title":"J. Neuro-Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0024","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1007\/s00417-021-05227-8","article-title":"A pathological indicator for dysthyroid optic neuropathy: tritan color vision deficiency","volume":"259","author":"Aylin","year":"2021","journal-title":"Graefes. Arch. Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0025","article-title":"Subclinical dysthyroid optic neuropathy: tritan deficiency as an early sign of dysthyroid optic neuropathy","author":"Garip Kuebler","year":"2020","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0026","doi-asserted-by":"crossref","DOI":"10.1530\/ETJ-24-0315","article-title":"Differentiation versus dysfunction: thyroid hormone, deiodinases and retinal photoreceptors","volume":"14","author":"Ng","year":"2025","journal-title":"Eur. Thyroid. J."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0027","first-page":"298","article-title":"Quantitative diagnosis of defective color vision. A comparative evaluation of the Ishihara test, the Farnsworth dichotomous test and the Hardy-Rand-Rittler polychromatic plates","volume":"51","author":"Crone","year":"1961","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0028","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1444-0938.2006.00015.x","article-title":"The new Richmond HRR pseudoisochromatic test for colour vision is better than the Ishihara test","volume":"89","author":"Cole","year":"2010","journal-title":"Clin. Exp. Optom."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0029","doi-asserted-by":"crossref","first-page":"A186","DOI":"10.1364\/JOSAA.31.00A186","article-title":"Comparison of the Richmond HRR 4th edition and Farnsworth-Munsell 100 Hue Test for quantitative assessment of tritan color deficiencies","volume":"31","author":"Foote","year":"2014","journal-title":"J. Opt. Soc. Am. Opt. Image Sci."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0030","article-title":"Accuracy of four commonly used color vision tests in the identification of cone disorders","volume":"20","author":"Alberta","year":"2013","journal-title":"Ophthalmic. Epidemiol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0031","doi-asserted-by":"crossref","unstructured":"Stephen J DJCEO. Clinical colour vision tests. 2004; 87.","DOI":"10.1111\/j.1444-0938.2004.tb05057.x"},{"key":"10.1016\/j.pdpdt.2025.105287_bib0032","unstructured":"French A., Rose K., Cornell E., Thompson K. The evolution of colour vision testing: the evolution of colour vision testing, 2008."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0033","first-page":"272","article-title":"Keeping an eye on Parkinson's disease: color vision and outer retinal thickness as simple and non-invasive biomarkers","author":"Lin","year":"2025","journal-title":"J. Neurol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0034","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/nrn2094","article-title":"The machinery of colour vision","volume":"8","author":"Solomon","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0035","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0166-2236(98)01245-4","article-title":"Neuronal chemistry and functional organization in the primate visual system","volume":"21","author":"Hendry","year":"1998","journal-title":"Trends. Neurosci."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0036","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1080\/01676830.2020.1846761","article-title":"Reddy Pappuru R. Retinal vascularity, nerve fiber, and ganglion cell layer thickness in thyroid eye disease on optical coherence tomography angiography","volume":"41","author":"Dave","year":"2022","journal-title":"Orbit."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0037","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s40662-022-00301-6","article-title":"Peripapillary structural and microvascular alterations in early dysthyroid optic neuropathy","volume":"9","author":"Wu","year":"2022","journal-title":"Eye Vis."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0038","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/13816810490498341","article-title":"Color vision testing","volume":"25","author":"Melamud","year":"2004","journal-title":"Ophthalmic. Genet."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0039","first-page":"195","article-title":"Colour vision defects acquired in diseases of the eye","volume":"17","author":"Cox","year":"1960","journal-title":"Br. J. Physiol. Opt."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0040","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0039-6257(87)90070-1","article-title":"Acquired dyschromatopsias","volume":"32","author":"Hart","year":"1987","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2025.105287_bib0041","first-page":"276","article-title":"Clinical colour vision tests","volume":"87","author":"DS","year":"2010","journal-title":"Clin. Exp. Optom."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157210002500818X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S157210002500818X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:42:28Z","timestamp":1789688548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S157210002500818X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":41,"alternative-id":["S157210002500818X"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.105287","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of colour defects and microvascular abnormalities in dysthyroid optic neuropathy using optical coherence tomography angiography","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.105287","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105287"}}