{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:01:18Z","timestamp":1775145678943,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:00:00Z","timestamp":1766448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Government of Japan Ministry of Education Culture Sports Science and Technology","doi-asserted-by":"publisher","award":["22K12768"],"award-info":[{"award-number":["22K12768"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.pdpdt.2025.105330","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T08:09:50Z","timestamp":1766563790000},"page":"105330","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Monte Carlo-based estimation of NIR-PDT efficacy with and without breast compression in early-stage breast cancer"],"prefix":"10.1016","volume":"57","author":[{"given":"Yugo","family":"Minegishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8257-3085","authenticated-orcid":false,"given":"Yasutomo","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pdpdt.2025.105330_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.breast.2024.103862","article-title":"Survival feature and trend of female breast cancer: a comprehensive review of survival analysis from cancer registration data","volume":"79","author":"Tang","year":"2025","journal-title":"Breast"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0002","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bbe.2024.01.002","article-title":"Breast cancer diagnosis: a systematic review","volume":"44","author":"Wen","year":"2024","journal-title":"Biocybern. Biomed. Eng"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0003","doi-asserted-by":"crossref","DOI":"10.1186\/bcr2092","article-title":"Breast cancer tumor growth estimated through mammography screening data","volume":"10","author":"Weedon-Fekj\u00e6r","year":"2008","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0004","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.2214\/AJR.09.3568","article-title":"Breast cancers not detected at MRI: review of false-negative lesions","volume":"194","author":"Shimauchi","year":"2010","journal-title":"Am. J. Roentgenol"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0005","article-title":"Recent progress on NIR-II photothermal therapy","volume":"9","author":"Zhang","year":"2021","journal-title":"Front. Chem"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0006","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1021\/acs.accounts.9b00273","article-title":"Near-infrared photoimmunotherapy of cancer","volume":"52","author":"Kobayashi","year":"2019","journal-title":"Acc. Chem. Res"},{"issue":"13","key":"10.1016\/j.pdpdt.2025.105330_bib0007","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.3390\/cancers15133400","article-title":"In vitro comparative study of near-infrared photoimmunotherapy and photodynamic therapy","volume":"15","author":"Yamashita","year":"2023","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0008","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1021\/cr5004198","article-title":"Nanoparticles in photodynamic therapy","volume":"115","author":"Lucky","year":"2015","journal-title":"Chem. Rev"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0009","doi-asserted-by":"crossref","first-page":"18965","DOI":"10.1021\/acs.langmuir.5c01514","article-title":"Gold-enhanced lanthanide nanomedicine for near-infrared photodynamic therapy","volume":"41","author":"Ali","year":"2025","journal-title":"Langmuir"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2025.104498","article-title":"Fluorescence molecular imaging-guided photodynamic therapy for early breast cancer in the prone position: feasibility evaluation with Monte Carlo simulations","volume":"52","author":"Minegishi","year":"2025","journal-title":"Photodiagnosis Photodyn. Ther"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0011","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.30.S3.S34110","article-title":"Prediction of the photodynamic therapy effect using digital breast phantoms from patients with breast cancer via Monte Carlo simulations","volume":"30","author":"Minegishi","year":"2025","journal-title":"J. Biomed. Opt"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0012","doi-asserted-by":"crossref","first-page":"41100","DOI":"10.1021\/acsami.9b16237","article-title":"Upconversion system with quantum dots as sensitizer: improved photoluminescence and PDT efficiency","volume":"11","author":"Song","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0013","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1002\/mp.14826","article-title":"Dataset of patient-derived digital breast phantoms for in silico studies in breast computed tomography, digital breast tomosynthesis, and digital mammography","volume":"48","author":"Sarno","year":"2021","journal-title":"Med. Phys"},{"issue":"11","key":"10.1016\/j.pdpdt.2025.105330_bib0014","doi-asserted-by":"crossref","first-page":"961","DOI":"10.3390\/diagnostics10110961","article-title":"Monte Carlo modeling of shortwave-infrared fluorescence photon migration in voxelized Media for the detection of breast cancer","volume":"10","author":"Iida","year":"2020","journal-title":"Diagnostics"},{"issue":"6","key":"10.1016\/j.pdpdt.2025.105330_bib0015","article-title":"Optical properties of normal and cancerous human skin in the visible and near-infrared spectral range","volume":"11","author":"Vladimirovna Salomatina","year":"2006","journal-title":"J. Biomed. Opt"},{"issue":"2","key":"10.1016\/j.pdpdt.2025.105330_bib0016","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4103\/tjps.TJPS_2_17","article-title":"Measurement of epidermis, dermis, and total skin thicknesses from six different body regions with a new ethical histometric technique","volume":"26","author":"Oltulu","year":"2018","journal-title":"Turk. J. Plast. Surg."},{"issue":"11","key":"10.1016\/j.pdpdt.2025.105330_bib0017","doi-asserted-by":"crossref","first-page":"R37","DOI":"10.1088\/0031-9155\/58\/11\/R37","article-title":"Optical properties of biological tissues: a review","volume":"58","author":"Jacques","year":"2013","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0018","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10549-007-9582-z","article-title":"Diffuse optical imaging of the healthy and diseased breast: a systematic review","volume":"108","author":"Leff","year":"2008","journal-title":"Breast Cancer Res. Treat"},{"issue":"9","key":"10.1016\/j.pdpdt.2025.105330_bib0019","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1088\/0031-9155\/35\/9\/010","article-title":"Optical properties of normal and diseased human breast tissues in the visible and near infrared","volume":"35","author":"Peters","year":"1990","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0020","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/jnci\/djh164","article-title":"Ductal carcinoma in situ, complexities and challenges","volume":"96","author":"Leonard","year":"2004","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0021","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3233\/THC-2007-15404","article-title":"Mechanics of the normal woman's breast","volume":"15","author":"Gefen","year":"2007","journal-title":"Technol. Health Care."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0022","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1109\/10.730440","article-title":"Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: fixed-focus and antenna-array sensors","volume":"45","author":"Hagness","year":"1998","journal-title":"IEEE Trans. Biomed. Eng"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0023","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1021\/acsnano.0c00043","article-title":"Semiconducting polymer nanoparticles as theranostic system for near-infrared-II fluorescence imaging and photothermal therapy under safe laser fluence","volume":"14","author":"Yang","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0024","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1111\/j.1365-2133.2008.08882.x","article-title":"Guidelines for topical photodynamic therapy: update","volume":"159","author":"Morton","year":"2008","journal-title":"Br. J. Dermatol"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0025","doi-asserted-by":"crossref","DOI":"10.1117\/1.3562540","article-title":"Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas","volume":"16","author":"Valentine","year":"2011","journal-title":"J. Biomed. Opt"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0026","doi-asserted-by":"crossref","first-page":"7168","DOI":"10.1364\/AO.37.007168","article-title":"Modeling of photosensitizer fluorescence emission and photobleaching for photodynamic therapy dosimetry","volume":"37","author":"Farrell","year":"1998","journal-title":"Appl. Opt"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0027","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1007\/s003300000465","article-title":"Role of ultrasonography in the detection of intraductal spread of breast cancer: correlation with pathologic findings, mammography and MR imaging","volume":"10","author":"Satake","year":"2000","journal-title":"Eur. Radiol"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0028","unstructured":"https:\/\/www.uclahealth.org\/departments\/radiology\/education\/breast-imaging-teaching-resources\/screening-mammogram\/positioning-and-technique?utm_source=chatgpt.com, 2025 [Accessed October 7, 2025]."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0029","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12905-015-0185-2","article-title":"Pain-preventing strategies in mammography: an observational study of simultaneously recorded pain and breast mechanics throughout the entire breast compression cycle","volume":"15","author":"de Groot","year":"2015","journal-title":"BMC Womens Health"},{"issue":"68","key":"10.1016\/j.pdpdt.2025.105330_bib0030","doi-asserted-by":"crossref","first-page":"113194","DOI":"10.18632\/oncotarget.20179","article-title":"Avoiding thermal injury during near-infrared photoimmunotherapy (NIR-PIT): the importance of NIR light power density","volume":"8","author":"Okuyama","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0031","doi-asserted-by":"crossref","first-page":"3873","DOI":"10.1038\/s41598-019-39502-w","article-title":"Deep-tissue optical imaging of near cellular-sized features","volume":"9","author":"Dang","year":"2019","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.pdpdt.2025.105330_bib0032","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.20.2.026002","article-title":"Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance","volume":"20","author":"Kolste","year":"2015","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0033","series-title":"Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86684E","article-title":"Pressure distribution in mammography: compression of breasts with malignant tumor masses","author":"F\u00f6rnvik","year":"2013"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0034","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.30.1.018001","article-title":"Photosensitizer spatial heterogeneity and its impact on personalized interstitial photodynamic therapy treatment planning","volume":"30","author":"Saeidi","year":"2025","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2025.104689","article-title":"Are blood flow and blood volume predictors of localized photosensitizer accumulation in the brain?","volume":"54","author":"Saeidi","year":"2025","journal-title":"Photodiagn. Photodyn. Ther."},{"issue":"1","key":"10.1016\/j.pdpdt.2025.105330_bib0036","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12880-025-01698-x","article-title":"Study on heterogeneity of vascularity and cellularity via multiparametric MRI habitat imaging in breast cancer","volume":"25","author":"Zhang","year":"2025","journal-title":"BMC Med. Imaging"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0037","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3390\/ph12040163","article-title":"Fighting hypoxia to improve PDT","volume":"12","author":"Larue","year":"2019","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.pdpdt.2025.105330_bib0038","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2020.01040","article-title":"Bioengineering the oxygen-deprived tumor microenvironment within a three-dimensional platform for studying tumor-immune interactions","volume":"8","author":"Bhattacharya","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0039","first-page":"9694","article-title":"Investigating the impact of oxygen concentration and blood flow variation on photodynamic therapy","author":"Penjweini","year":"2016","journal-title":"SPIE Proc."},{"key":"10.1016\/j.pdpdt.2025.105330_bib0040","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.29.2.025001","article-title":"Simulating photodynamic therapy for the treatment of glioblastoma using Monte Carlo radiative transport","volume":"29","author":"Finlayson","year":"2024","journal-title":"J. Biomed. Opt"},{"issue":"2","key":"10.1016\/j.pdpdt.2025.105330_bib0041","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.acra.2013.10.009","article-title":"Blood flow reduction in breast tissue due to mammographic compression","volume":"21","author":"Busch","year":"2014","journal-title":"Acad. Radiol."},{"issue":"12","key":"10.1016\/j.pdpdt.2025.105330_bib0042","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1364\/BOE.4.002911","article-title":"Hemodynamic signature of breast cancer under fractional mammographic compression using a dynamic diffuse optical tomography system","volume":"4","author":"Carp","year":"2013","journal-title":"Biomed. Opt. Expr."},{"issue":"4","key":"10.1016\/j.pdpdt.2025.105330_bib0043","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1109\/2944.577320","article-title":"Effects of compression on soft tissue optical properties","volume":"2","author":"Chan","year":"1996","journal-title":"IEEE J. Sel. Top. Quantum Electron."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025008609?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100025008609?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T15:21:14Z","timestamp":1775143274000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100025008609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":43,"alternative-id":["S1572100025008609"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.105330","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monte Carlo-based estimation of NIR-PDT efficacy with and without breast compression in early-stage breast cancer","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2025.105330","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105330"}}