{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:40:43Z","timestamp":1793018443444,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.pdpdt.2026.105451","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:12:34Z","timestamp":1774487554000},"page":"105451","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Evaluation of the efficacy and safety of photodynamic therapy after laser pretreatment for treating cervical high-grade intraepithlial lesions in patients of childbearing age: a non-randomized controlled prospective study"],"prefix":"10.1016","volume":"59","author":[{"given":"Mengting","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuxiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyin","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxuan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baohua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.pdpdt.2026.105451_bib0001","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2020.101980","article-title":"Photodynamic therapy as an alternative treatment in patients with invasive cutaneous SCC where surgery is not feasible: single center experience","volume":"32","author":"Zhang","year":"2020","journal-title":"Photodiagnosis Photodyn. Ther."},{"issue":"1","key":"10.1016\/j.pdpdt.2026.105451_bib0003","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jncc.2024.01.006","article-title":"Cancer incidence and mortality in China, 2022","volume":"4","author":"Han","year":"2024","journal-title":"J. Natl. Cancer Center"},{"key":"10.1016\/j.pdpdt.2026.105451_bib0004","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2024.1480983","article-title":"Cervical intraepithelial neoplasia and cervical cancer in Hunan province, China, 2020-2023","volume":"14","author":"Zhou","year":"2024","journal-title":"Front. Oncol."},{"issue":"5","key":"10.1016\/j.pdpdt.2026.105451_bib0005","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1470-2045(08)70103-7","article-title":"Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study","volume":"9","author":"McCredie","year":"2008","journal-title":"Lancet Oncol."},{"issue":"1","key":"10.1016\/j.pdpdt.2026.105451_bib0006","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ygyno.2020.01.023","article-title":"The risk of cervical cancer after cervical intraepithelial neoplasia grade 3: a population-based cohort study with 80,442 women","volume":"157","author":"Loopik","year":"2020","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"10.1016\/j.pdpdt.2026.105451_bib0007","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.soncn.2019.02.003","article-title":"Cervical cancer: an overview of pathophysiology and management","volume":"35","author":"Johnson","year":"2019","journal-title":"Semin. Oncol. Nurs."},{"issue":"6","key":"10.1016\/j.pdpdt.2026.105451_bib0008","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1007\/s00404-012-2493-1","article-title":"Assessment of cervical intraepithelial neoplasia (CIN) with colposcopic biopsy and efficacy of loop electrosurgical excision procedure (LEEP)","volume":"286","author":"Duesing","year":"2012","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0009","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.2147\/IJWH.S468086","article-title":"Differential analysis of pregnancy outcomes after treatment of HIFU and LEEP in patients with cervical high-grade squamous intraepithelial lesions","volume":"16","author":"Shen","year":"2024","journal-title":"Int. J. Womens Health"},{"issue":"4","key":"10.1016\/j.pdpdt.2026.105451_bib0010","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s00404-022-06807-7","article-title":"Certification as dysplasia unit and its impact on large loop electrosurgical excision (LEEP)","volume":"307","author":"Hanczuk","year":"2023","journal-title":"Arch. Gynecol. Obstet."},{"issue":"18","key":"10.1016\/j.pdpdt.2026.105451_bib0011","doi-asserted-by":"crossref","first-page":"9054","DOI":"10.7150\/thno.62479","article-title":"Recent advances in photosensitizers as multifunctional theranostic agents for imaging-guided photodynamic therapy of cancer","volume":"11","author":"Sarbadhikary","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.pdpdt.2026.105451_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2020.12.073","article-title":"Combination of talaporfin photodynamic therapy and poly (ADP-Ribose) polymerase (PARP) inhibitor in gastric cancer","volume":"539","author":"Tanaka","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.pdpdt.2026.105451_bib0013","article-title":"HPV negative conversion following Hiporfin PDT for HPV associated HSIL in the female lower reproductive tract","volume":"15","author":"Liu","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejogrb.2025.114026","article-title":"Comparison of 5-ALA-PDT and LEEP for cervical squamous intraepithelial neoplasia: a systematic review and meta-analysis","volume":"311","author":"Li","year":"2025","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"4","key":"10.1016\/j.pdpdt.2026.105451_bib0015","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/ijgc-2022-004213","volume":"33","author":"Kesic","year":"2023","journal-title":"Int. J. Gynecol. Cancer."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2022.102993","article-title":"Chinese expert consensus on the clinical applications of aminolevulinic acid-based photodynamic therapy in female lower genital tract diseases (2022)","volume":"39","author":"Qiu","year":"2022","journal-title":"Photodiagnosis Photodyn. Ther."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2024.104017","article-title":"Efficacy and influencing factors of CO2 laser, topical photodynamic therapy versus therapy combined with CO2 laser pretreatment for vaginal low-grade squamous intraepithelial lesions with high-risk HPV infection","volume":"46","author":"Li","year":"2024","journal-title":"Photodiagnosis Photodyn. Ther."},{"issue":"1","key":"10.1016\/j.pdpdt.2026.105451_bib0018","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0020-7292(99)00162-9","article-title":"Treatment outcomes for squamous intraepithelial lesions","volume":"68","author":"Nuovo","year":"2000","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.pdpdt.2026.105451_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2023.103721","article-title":"Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions","volume":"43","author":"Feng","year":"2023","journal-title":"Photodiagnosis Photodyn. Ther."},{"issue":"5","key":"10.1016\/j.pdpdt.2026.105451_bib0020","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1002\/ijc.35450","article-title":"Efficacy of ALA-PDT in treating cervical low-grade squamous intraepithelial lesions with high-risk HPV patients: a multicentre randomized controlled trial","volume":"157","author":"Wei","year":"2025","journal-title":"Int. J. Cancer"}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100026001183?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100026001183?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:25:05Z","timestamp":1793017505000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100026001183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":20,"alternative-id":["S1572100026001183"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2026.105451","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of the efficacy and safety of photodynamic therapy after laser pretreatment for treating cervical high-grade intraepithlial lesions in patients of childbearing age: a non-randomized controlled prospective study","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2026.105451","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105451"}}