{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T05:25:39Z","timestamp":1793856339662,"version":"4.6.1"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Photodiagnosis and Photodynamic Therapy"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.pdpdt.2026.105597","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:12:06Z","timestamp":1785539526000},"page":"105597","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Spatial heterogeneity of retinal structural and microvascular alterations across different degrees of myopia: a 17-sector ETDRS analysis using wide-field SS-OCTA"],"prefix":"10.1016","volume":"61","author":[{"given":"Hongyue","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuehua","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junguo","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.pdpdt.2026.105597_bib0001","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmology."},{"issue":"7","key":"10.1016\/j.pdpdt.2026.105597_bib0002","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/eye.2016.47","article-title":"Advances of optical coherence tomography in myopia and pathologic myopia","volume":"30","author":"Ng","year":"2016","journal-title":"Eye"},{"key":"10.1016\/j.pdpdt.2026.105597_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2017.11.003","article-title":"Optical coherence tomography angiography","volume":"64","author":"Spaide","year":"2018","journal-title":"Prog. Retinal Eye Res."},{"key":"10.1016\/j.pdpdt.2026.105597_bib0004","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40942-015-0005-8","article-title":"A review of optical coherence tomography angiography (OCTA)","volume":"1","author":"de Carlo","year":"2015","journal-title":"Int. J. Retina Vitr."},{"key":"10.1016\/j.pdpdt.2026.105597_bib0005","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.preteyeres.2017.07.002","article-title":"Optical coherence tomography angiography: a comprehensive review of current methods and clinical applications","volume":"60","author":"Kashani","year":"2017","journal-title":"Prog. Retinal Eye Res."},{"issue":"2","key":"10.1016\/j.pdpdt.2026.105597_bib0006","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/eye.2017.181","article-title":"An overview of the clinical applications of optical coherence tomography angiography","volume":"32","author":"Tan","year":"2018","journal-title":"Eye"},{"key":"10.1016\/j.pdpdt.2026.105597_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2026.105424","article-title":"Macular microvascular remodeling in non-pathological high myopia revealed by optical coherence tomography angiography","volume":"58","author":"Zhu","year":"2026","journal-title":"Photodiagnosis. Photodyn. Ther."},{"issue":"6","key":"10.1016\/j.pdpdt.2026.105597_bib0008","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1038\/s41433-020-0824-1","article-title":"Alterations in optical coherence tomography angiography findings in patients with high myopia","volume":"34","author":"Ucak","year":"2020","journal-title":"Eye"},{"issue":"2","key":"10.1016\/j.pdpdt.2026.105597_bib0009","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-013571","article-title":"Vascular flow density in pathological myopia: an optical coherence tomography angiography study","volume":"7","author":"Mo","year":"2017","journal-title":"BMJ Open."},{"issue":"8","key":"10.1016\/j.pdpdt.2026.105597_bib0010","first-page":"1419","article-title":"Vessel density, retinal thickness, and choriocapillaris vascular flow in myopic eyes on OCT angiography. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle","volume":"256","author":"Milani","year":"2018","journal-title":"Ophthalmologie"},{"issue":"5","key":"10.1016\/j.pdpdt.2026.105597_bib0011","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1136\/bjophthalmol-2020-317632","article-title":"Quantitative OCT angiography of the retinal microvasculature and choriocapillaris in highly myopic eyes with myopic macular degeneration","volume":"106","author":"Zheng","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.pdpdt.2026.105597_bib0012","doi-asserted-by":"crossref","unstructured":"Su, L., Ji, Y.S., Tong, N., Sarraf, D., He, X., Sun, X., Xu, X., & Sadda, S.R. (2020). Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 258(6), 1173\u20131180. https:\/\/doi.org\/10.1007\/s00417-020-04639-2.","DOI":"10.1007\/s00417-020-04639-2"},{"issue":"16","key":"10.1016\/j.pdpdt.2026.105597_bib0013","first-page":"5736","article-title":"Changes in macular vascular density and retinal thickness in young myopic adults without pathological changes: an OCTA study","volume":"26","author":"Meng","year":"2022","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"9","key":"10.1016\/j.pdpdt.2026.105597_bib0014","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1038\/s41433-019-0438-7","article-title":"Association between retinal microvasculature and optic disc alterations in high myopia","volume":"33","author":"He","year":"2019","journal-title":"Eye"},{"issue":"1","key":"10.1016\/j.pdpdt.2026.105597_bib0015","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1159\/000543975","article-title":"Longitudinal changes in macular vessel density in high myopia on optical coherence tomography angiography","volume":"68","author":"Wu","year":"2025","journal-title":"Ophthalmic. Res."},{"issue":"6","key":"10.1016\/j.pdpdt.2026.105597_bib0016","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3109\/09286586.2011.602508","article-title":"Retinal vessel caliber and myopic retinopathy: the blue mountains eye study","volume":"18","author":"Li","year":"2011","journal-title":"Ophthalmic. Epidemiol."},{"issue":"14","key":"10.1016\/j.pdpdt.2026.105597_bib0017","doi-asserted-by":"crossref","first-page":"6020","DOI":"10.1167\/iovs.16-19542","article-title":"Retinal microvasculature alteration in high myopia","volume":"57","author":"Yang","year":"2016","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"10.1016\/j.pdpdt.2026.105597_bib0018","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ajo.2016.10.018","article-title":"Retinal microvascular network and microcirculation assessments in high myopia","volume":"174","author":"Li","year":"2017","journal-title":"Am. J. Ophthalmol."},{"issue":"12","key":"10.1016\/j.pdpdt.2026.105597_bib0019","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1038\/s41433-019-0573-1","article-title":"Deep perifoveal vessel density as an indicator of capillary loss in high myopia","volume":"33","author":"Cheng","year":"2019","journal-title":"Eye"},{"key":"10.1016\/j.pdpdt.2026.105597_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.mvr.2021.104169","article-title":"Thickness, vessel density of retina and choroid on OCTA in young adults (18-24 years old)","volume":"136","author":"Xiuyan","year":"2021","journal-title":"Microvasc. Res."},{"issue":"3","key":"10.1016\/j.pdpdt.2026.105597_bib0021","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/s41433-023-02712-8","article-title":"Correlation of the macular microvasculature to the axial length in pediatric patients with high axial refractive errors","volume":"38","author":"Shuaib","year":"2024","journal-title":"Eye"},{"key":"10.1016\/j.pdpdt.2026.105597_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.pdpdt.2024.104240","article-title":"Wide-field swept-source optical coherence tomography angiography (SS-OCTA) in the assessment of retinal vessel density and thickness in 4-to 16-year-old myopic children","volume":"48","author":"Mu","year":"2024","journal-title":"Photodiagnosis. Photodyn. Ther."},{"issue":"8","key":"10.1016\/j.pdpdt.2026.105597_bib0023","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.1167\/iovs.18-26085","article-title":"Photoreceptor degeneration is correlated with the deterioration of macular retinal sensitivity in high myopia","volume":"60","author":"Wang","year":"2019","journal-title":"Invest. Ophthalmol. Visual Sci."},{"issue":"4","key":"10.1016\/j.pdpdt.2026.105597_bib0024","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1167\/iovs.61.4.45","article-title":"Deep retinal capillary plexus decreasing correlated with the outer retinal layer alteration and visual acuity impairment in pathological myopia","volume":"61","author":"Ye","year":"2020","journal-title":"Invest. Ophthalmol. Visual Sci."},{"key":"10.1016\/j.pdpdt.2026.105597_bib0025","doi-asserted-by":"crossref","DOI":"10.1186\/s12880-026-02480-3","article-title":"Peripheral instability gradient in macular thickness measurements across five optical coherence tomography systems: a prospective cross-sectional study of inter-device agreement and clinical monitoring risk","author":"Akkan","year":"2026","journal-title":"BMC Med. Imaging"},{"key":"10.1016\/j.pdpdt.2026.105597_bib0026","article-title":"Advanced ultrawide-field optical coherence tomography angiography identifies previously undetectable changes in biomechanics-related parameters in nonpathological myopic fundus","volume":"10","author":"Zhang","year":"2022","journal-title":"Front. Bioeng. Biotechnol."}],"container-title":["Photodiagnosis and Photodynamic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100026002644?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1572100026002644?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T04:50:28Z","timestamp":1793854228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1572100026002644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":26,"alternative-id":["S1572100026002644"],"URL":"https:\/\/doi.org\/10.1016\/j.pdpdt.2026.105597","relation":{},"ISSN":["1572-1000"],"issn-type":[{"value":"1572-1000","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spatial heterogeneity of retinal structural and microvascular alterations across different degrees of myopia: a 17-sector ETDRS analysis using wide-field SS-OCTA","name":"articletitle","label":"Article Title"},{"value":"Photodiagnosis and Photodynamic Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pdpdt.2026.105597","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105597"}}