{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T16:40:03Z","timestamp":1748364003468,"version":"3.41.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"vor","delay-in-days":366,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","pediatr-neonatol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics & Neonatology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.pedneo.2015.02.004","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T06:20:52Z","timestamp":1430202052000},"page":"393-401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Neurometabolic Disorders-Related Early Childhood Epilepsy: A Single-Center Experience in Saudi Arabia"],"prefix":"10.1016","volume":"56","author":[{"given":"Sarar","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebtessam M.","family":"El Melegy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iman","family":"Talaat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amany","family":"Hosny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled K.","family":"Abu-Amero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pedneo.2015.02.004_bib1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1528-1167.2010.02522.x","article-title":"Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005\u20132009","volume":"51","author":"Berg","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.pedneo.2015.02.004_bib2","series-title":"The metabolic and molecular bases of inherited diseases","first-page":"3","article-title":"Genetics, biochemistry, and molecular bases of variant human phenotypes","author":"Beaudet","year":"2001"},{"key":"10.1016\/j.pedneo.2015.02.004_bib3","first-page":"20","article-title":"Recognition and diagnostic approach to acute metabolic disorders in the neonatal period","volume":"11","author":"Mohamed","year":"2011","journal-title":"Sudan J Paediatr"},{"key":"10.1016\/j.pedneo.2015.02.004_bib4","first-page":"6","article-title":"Treatment strategies for acute metabolic disorders in neonates","volume":"11","author":"Mohamed","year":"2011","journal-title":"Sudan J Paediatr"},{"key":"10.1016\/j.pedneo.2015.02.004_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02913305","article-title":"Neurometabolic disorders","volume":"22","author":"Panagariya","year":"2007","journal-title":"Indian J Clin Biochem"},{"key":"10.1016\/j.pedneo.2015.02.004_bib6","series-title":"Epilepsy in children","first-page":"65","article-title":"Disorders of metabolism and neurodegenerative disorders associated with epilepsy","author":"Poll-The","year":"2004"},{"key":"10.1016\/j.pedneo.2015.02.004_bib7","article-title":"Infantile epileptic syndromes and metabolic etiologies","volume":"17","author":"Vigevano","year":"2002","journal-title":"J Child Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib8","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/01.nrl.0000340787.30542.41","article-title":"Epilepsy in inherited metabolic disorders","volume":"14","author":"Pascual","year":"2008","journal-title":"Neurologist"},{"key":"10.1016\/j.pedneo.2015.02.004_bib9","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11910-005-0010-7","article-title":"Seizures and metabolic diseases","volume":"5","author":"Pearl","year":"2005","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.pedneo.2015.02.004_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1684\/j.1950-6945.2005.tb00106.x","article-title":"Epilepsy in inborn errors of metabolism","volume":"7","author":"Wolf","year":"2005","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.pedneo.2015.02.004_bib11","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/ana.20079","article-title":"POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion","volume":"55","author":"Naviaux","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib12","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1212\/01.WNL.0000091888.26232.FE","article-title":"Slowly progressive spread of\u00a0the stroke-like lesions in MELAS","volume":"61","author":"Iizuka","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.pedneo.2015.02.004_bib13","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/B978-0-444-52891-9.00056-7","article-title":"Epilepsy in inborn errors of metabolism","volume":"111","author":"Bahi-Buisson","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib14","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.pediatrneurol.2009.02.018","article-title":"Mitochondrial encephalomyopathy lactic acidosis and strokelike episodes mimicking occipital idiopathic epilepsy","volume":"41","author":"Cesaroni","year":"2009","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib15","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.eplepsyres.2009.09.020","article-title":"Mitochondria, oxidative stress, and temporal lobe epilepsy","volume":"88","author":"Waldbaum","year":"2010","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.pedneo.2015.02.004_bib16","first-page":"58","article-title":"A clinical investigation of 228 patients with phenylketonuria in Mainland China","volume":"30","author":"Yanling","year":"1999","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"10.1016\/j.pedneo.2015.02.004_bib17","first-page":"745","article-title":"Causes of symptomatic epilepsy in two first years of life children hospitalized in 2006-2007 years","volume":"65","author":"Kroczka","year":"2008","journal-title":"Przegl Lek"},{"key":"10.1016\/j.pedneo.2015.02.004_bib18","first-page":"5","article-title":"Clinical profile of epilepsy during the first two years of life","volume":"22","author":"Khreisat","year":"2006","journal-title":"Pak J Med Sci"},{"key":"10.1016\/j.pedneo.2015.02.004_bib19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/ajmg.a.36180","article-title":"Sanfilippo syndrome, glucose-6-phosphate dehydrogenase deficiency and sickle cell\/\u03b2+ thalassemia in a child: the burden of consanguinity","volume":"164A","author":"Mohamed","year":"2014","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.pedneo.2015.02.004_bib20","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.pediatrneurol.2009.05.005","article-title":"Early myoclonic encephalopathy and nonketotic hyperglycinemia","volume":"41","author":"Rossi","year":"2009","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib21","series-title":"Epilepsy in children","first-page":"257","article-title":"Progressive myoclonus epilepsies","author":"Dravet","year":"2004"},{"key":"10.1016\/j.pedneo.2015.02.004_bib22","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/WCO.0b013e3282f7007e","article-title":"Epileptic syndromes in infancy and childhood","volume":"21","author":"Nabbout","year":"2008","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.pedneo.2015.02.004_bib23","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1111\/j.1528-1167.2008.01877.x","article-title":"Status epilepticus in children with Alpers disease caused by POLG1 mutations: EEG and MRI features","volume":"50","author":"Wolf","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.pedneo.2015.02.004_bib24","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/j.1528-1167.2007.01423.x","article-title":"Severe myoclonic epilepsy in infancy: a systematic review and a meta-analysis of individual patient data","volume":"49","author":"Kassa\u00ef","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.pedneo.2015.02.004_bib25","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.braindev.2012.11.010","article-title":"Metabolic epilepsy: an update","volume":"35","author":"Papetti","year":"2013","journal-title":"Brain Dev"},{"key":"10.1016\/j.pedneo.2015.02.004_bib26","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrneurol.2010.92","article-title":"Genetic evaluation and counseling for epilepsy","volume":"6","author":"Pal","year":"2010","journal-title":"Nat Rev Neurol"}],"container-title":["Pediatrics & Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957215000510?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957215000510?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T16:26:58Z","timestamp":1748363218000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875957215000510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S1875957215000510"],"URL":"https:\/\/doi.org\/10.1016\/j.pedneo.2015.02.004","relation":{},"ISSN":["1875-9572"],"issn-type":[{"type":"print","value":"1875-9572"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurometabolic Disorders-Related Early Childhood Epilepsy: A Single-Center Experience in Saudi Arabia","name":"articletitle","label":"Article Title"},{"value":"Pediatrics & Neonatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pedneo.2015.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}