{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T09:45:49Z","timestamp":1777974349692,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T00:00:00Z","timestamp":1583798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"KK Hospital"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","pediatr-neonatol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics & Neonatology"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.pedneo.2020.03.003","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T22:42:22Z","timestamp":1584052942000},"page":"385-392","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A single-center observational study on congenital diaphragmatic hernia: Outcome, predictors of mortality and experience from a tertiary perinatal center in Singapore"],"prefix":"10.1016","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1046-1674","authenticated-orcid":false,"given":"Wan-Yee","family":"Teo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavani","family":"Sriram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AA Abdul","family":"Alim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5861-8191","authenticated-orcid":false,"given":"Xucong","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.S.","family":"Rajadurai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pedneo.2020.03.003_bib1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0095-5108(18)30201-X","article-title":"Congenital diaphragmatic hernia. Epidemiology and outcome","volume":"23","author":"Langham","year":"1996","journal-title":"Clin Perinatol"},{"issue":"3","key":"10.1016\/j.pedneo.2020.03.003_bib2","article-title":"Late versus early surgical correction for congenital diaphragmatic hernia in newborn infants","author":"Moyer","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.pedneo.2020.03.003_bib3","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1164\/rccm.200204-304CC","article-title":"Congenital diaphragmatic hernia","volume":"166","author":"Bohn","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.pedneo.2020.03.003_bib4","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/0022-3468(95)90042-X","article-title":"Congenital diaphragmatic hernia: survival treated with very delayed surgery, spontaneous respiration, and no chest tube","volume":"30","author":"Wung","year":"1995","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib5","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s003830200006","article-title":"Congenital diaphragmatic hernia: experience without extracorporeal membrane oxygenation","volume":"18","author":"Al-Shanafey","year":"2002","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.pedneo.2020.03.003_bib6","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/jpc.12508","article-title":"Congenital diaphragmatic hernia","volume":"50","author":"Leeuwen","year":"2014","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.pedneo.2020.03.003_bib7","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/jpsu.2003.50194","article-title":"Analysis of an improved survival rate for congenital diaphragmatic hernia","volume":"38","author":"Downard","year":"2003","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jpedsurg.2003.11.009","article-title":"Impact of a current treatment protocol on outcome of high-risk congenital diaphragmatic hernia","volume":"39","author":"Bagolan","year":"2004","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib9","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1016\/j.jpedsurg.2008.12.021","article-title":"Congenital Diaphragmatic Hernia Study Group. Factors associated with survival in infants with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenation: a report from the Congenital Diaphragmatic Hernia Study Group","volume":"44","author":"Seetharamaiah","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0022-3468(97)90104-4","article-title":"Mortality among infants with high-risk congenital diaphragmatic hernia in Singapore","volume":"32","author":"Chan","year":"1997","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib11","first-page":"715","article-title":"Congenital diaphragmatic hernia in a developing country","volume":"49","author":"Bhat","year":"2008","journal-title":"Singapore Med J"},{"key":"10.1016\/j.pedneo.2020.03.003_bib12","doi-asserted-by":"crossref","first-page":"e651","DOI":"10.1542\/peds.2006-3040","article-title":"Defect size determines survival in infants with congenital diaphragmatic hernia","volume":"120","author":"Lally","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2020.03.003_bib13","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/0022-3468(94)90290-9","article-title":"Congenital diaphragmatic hernia and associated anomalies: their incidence, identification, and impact on prognosis","volume":"29","author":"Fauza","year":"1994","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib14","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.ajog.2007.07.001","article-title":"Liver position and lung-to-head ratio for prediction of extracorporeal membrane oxygenation and survival in isolated left congenital diaphragmatic hernia","volume":"197","author":"Hedrick","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.pedneo.2020.03.003_bib15","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.ajog.2006.04.004","article-title":"FETO Task Group. Fetal lung-to-head ratio in the prediction of survival in severe left-sided diaphragmatic hernia treated by fetal endoscopic tracheal occlusion (FETO)","volume":"195","author":"Jani","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.pedneo.2020.03.003_bib16","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.jpedsurg.2011.03.046","article-title":"Late gestation fetal magnetic resonance imaging-derived total lung volume predicts postnatal survival and need for extracorporeal membrane oxygenation support in isolated congenital diaphragmatic hernia","volume":"46","author":"Lee","year":"2011","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib17","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/sj.jp.7211257","article-title":"Canadian Neonatal Network. SNAP-II predicts mortality among infants with congenital diaphragmatic hernia","volume":"25","author":"Skarsgard","year":"2005","journal-title":"J Perinatol"},{"key":"10.1016\/j.pedneo.2020.03.003_bib18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1159\/000319064","article-title":"Survival in congenital diaphragmatic hernia: use of predictive equations in the ECMO population","volume":"99","author":"Hoffman","year":"2011","journal-title":"Neonatology"},{"key":"10.1016\/j.pedneo.2020.03.003_bib19","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/jpsu.2001.20032","article-title":"Estimating disease severity of congenital diaphragmatic hernia in the first 5 minutes of life","volume":"36","author":"Congenital Diaphragmatic Hernia Study Group","year":"2001","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib20","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.jpedsurg.2018.11.014","article-title":"Prognostic value of the oxygenation index to predict survival and timing of surgery in infants with congenital diaphragmatic hernia","volume":"54","author":"Tan","year":"2019","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib21","first-page":"142","article-title":"Early outcome of congenital diaphragmatic hernia in a Malaysian tertiary centre","volume":"49","author":"Rohana","year":"2008","journal-title":"Singapore Med J"},{"key":"10.1016\/j.pedneo.2020.03.003_bib22","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.jpedsurg.2004.01.032","article-title":"Apparent truth about congenital diaphragmatic hernia: a population-based database is needed to establish benchmarking for clinical outcomes for CDH","volume":"39","author":"Ontario Congenital Anomalies Study Group","year":"2004","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib23","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1001\/jama.1994.03510290064038","article-title":"A prospective study of the outcome for fetuses with diaphragmatic hernia","volume":"271","author":"Harrison","year":"1994","journal-title":"JAMA"},{"key":"10.1016\/j.pedneo.2020.03.003_bib24","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1542\/peds.112.3.532","article-title":"Nihilism in the 1990s: the true mortality of congenital diaphragmatic hernia","volume":"112","author":"Stege","year":"2003","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.pedneo.2020.03.003_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000399.pub2","article-title":"Nitric oxide for respiratory failure in infants born at or near term","author":"Finer","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.pedneo.2020.03.003_bib26","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1542\/peds.99.6.838","article-title":"Inhaled nitric oxide and hypoxic respiratory failure in infants with congenital diaphragmatic hernia. The Neonatal Inhaled Nitric Oxide Study Group (NINOS)","volume":"99","year":"1997","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2020.03.003_bib27","doi-asserted-by":"crossref","first-page":"e420","DOI":"10.1542\/peds.2013-2644","article-title":"Inhaled nitric oxide use in neonates with congenital diaphragmatic hernia","volume":"134","author":"Campbell","year":"2014","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2020.03.003_bib28","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/pd.654","article-title":"Congenital diaphragmatic hernia: an evaluation of the prognostic value of the lung-to-head ratio and other prenatal parameters","volume":"23","author":"Laudy","year":"2003","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.pedneo.2020.03.003_bib29","first-page":"131","article-title":"Prediction of outcome in infants with congenital diaphragmatic hernia or severe diaphragmatic eventration","volume":"45","author":"Yao","year":"2004","journal-title":"Acta Paediatr Taiwan"},{"key":"10.1016\/j.pedneo.2020.03.003_bib30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jpedsurg.2010.09.060","article-title":"Protocolized management of infants with congenital diaphragmatic hernia: effect on survival","volume":"46","author":"Antonoff","year":"2011","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.pedneo.2020.03.003_bib31","article-title":"Congenital diaphragmatic hernia: 25 years of shared knowledge; what about survival?","author":"Lakshminrusimha","year":"2019","journal-title":"J Pediatr (Rio J)"}],"container-title":["Pediatrics & Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957220300425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957220300425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T14:54:43Z","timestamp":1761749683000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875957220300425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S1875957220300425"],"URL":"https:\/\/doi.org\/10.1016\/j.pedneo.2020.03.003","relation":{},"ISSN":["1875-9572"],"issn-type":[{"value":"1875-9572","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A single-center observational study on congenital diaphragmatic hernia: Outcome, predictors of mortality and experience from a tertiary perinatal center in Singapore","name":"articletitle","label":"Article Title"},{"value":"Pediatrics & Neonatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pedneo.2020.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Taiwan Pediatric Association. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}