{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:25:56Z","timestamp":1787577956683,"version":"build-2736575974"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","pediatr-neonatol.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pediatrics & Neonatology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.pedneo.2025.08.016","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:24:35Z","timestamp":1771028675000},"page":"523-531","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal transmission, neonatal outcomes, and predictors of adverse effects in congenital cytomegalovirus infection"],"prefix":"10.1016","volume":"67","author":[{"given":"Maria Teresa","family":"Garozzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basilio","family":"Pecorino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graziella","family":"Poli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Maiolino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Sciuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Scalia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martino","family":"Ruggieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Polizzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5231-7921","authenticated-orcid":false,"given":"Andrea D.","family":"Pratic\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pedneo.2025.08.016_bib1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/rmv.655","article-title":"Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection","volume":"20","author":"Cannon","year":"2010","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib2","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1128\/CMR.00062-12","article-title":"The \u201csilent\u201d global burden of congenital cytomegalovirus","volume":"26","author":"Manicklal","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.pedneo.2025.08.016_bib3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fped.2020.00013","article-title":"Congenital Cytomegalovirus Infection: A Narrative Review of the Issues in Screening and Management From a Panel of European Experts","volume":"8","author":"Lazzarotto","year":"2020","journal-title":"Front Pediatr"},{"key":"10.1016\/j.pedneo.2025.08.016_bib4","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1093\/infdis\/168.3.552","article-title":"Maternal age and congenital cytomegalovirus infection: screening of two diverse newborn populations, 1980\u20131990","volume":"168","author":"Fowler","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1016\/j.pedneo.2025.08.016_bib5","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/00006454-199108000-00008","article-title":"Cytomegalovirus and child daycare: risk factors for maternal infection","volume":"10","author":"Adler","year":"1991","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.pedneo.2025.08.016_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/rmv.535","article-title":"Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection","volume":"17","author":"Kenneson","year":"2007","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib7","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1001\/jama.289.8.1008","article-title":"Maternal immunity and prevention of congenital cytomegalovirus infection","volume":"289","author":"Fowler","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.pedneo.2025.08.016_bib8","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1128\/CMR.15.4.680-715.2002","article-title":"Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant","volume":"15","author":"Revello","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.pedneo.2025.08.016_bib9","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jcv.2007.10.015","article-title":"New advances in the diagnosis of congenital cytomegalovirus infection","volume":"41","author":"Lazzarotto","year":"2008","journal-title":"J Clin Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib10","doi-asserted-by":"crossref","first-page":"e0293869","DOI":"10.1371\/journal.pone.0293869","article-title":"Burden of sequelae and healthcare resource utilization in the first year of life in infants born with congenital cytomegalovirus (cCMV) infection in Germany: A retrospective statutory health insurance claims database analysis","volume":"18","author":"de Lepper","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.pedneo.2025.08.016_bib11","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/rmv.544","article-title":"New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection","volume":"17","author":"Dollard","year":"2007","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib12","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2458-5-70","article-title":"Washing our hands of the congenital cytomegalovirus disease epidemic","volume":"5","author":"Cannon","year":"2005","journal-title":"BMC Public Health"},{"issue":"Suppl 4","key":"10.1016\/j.pedneo.2025.08.016_bib13","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/j.jcv.2009.09.003","article-title":"Does hygiene counseling have an impact on the rate of CMV primary infection during pregnancy? Results of a 3-year prospective study in a French hospital","volume":"46","author":"Vauloup-Fellous","year":"2009","journal-title":"J Clin Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.bpobgyn.2016.10.005","article-title":"Fetal cytomegalovirus infection","volume":"38","author":"Leruez-Ville","year":"2017","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib15","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3390\/v10080405","article-title":"Maternal immunity and the natural history of congenital human cytomegalovirus infection","volume":"10","author":"Britt","year":"2018","journal-title":"Viruses"},{"key":"10.1016\/j.pedneo.2025.08.016_bib16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/audiolres15010002","article-title":"Predictive Factors for Hearing Loss in Congenital Cytomegalovirus Infection","volume":"15","author":"Corazzi","year":"2024","journal-title":"Audiol Res"},{"key":"10.1016\/j.pedneo.2025.08.016_bib17","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1111\/j.1471-0528.2009.02139.x","article-title":"A 2-year study on CMV infection during pregnancy in a French hospital","volume":"116","author":"Picone","year":"2009","journal-title":"BJOG"},{"key":"10.1016\/j.pedneo.2025.08.016_bib18","unstructured":"US Centers for Disease Control and Prevention (CDC). Cytomegalovirus (CMV) and congenital CMV infection. Atlanta, GA: Centers for Disease Control and Prevention. Available at https:\/\/www.cdc.gov\/cmv\/."},{"key":"10.1016\/j.pedneo.2025.08.016_bib19","unstructured":"World Health Organization (WHO). Congenital infections: CMV. Geneva, Switzerland: World Health Organization. Available at https:\/\/www.who.int\/."},{"key":"10.1016\/j.pedneo.2025.08.016_bib20","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1542\/peds.2014-1173","article-title":"Hearing loss and congenital CMV infection: a systematic review","volume":"134","author":"Goderis","year":"2014","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2025.08.016_bib21","doi-asserted-by":"crossref","first-page":"e177","DOI":"10.1016\/S1473-3099(17)30143-3","article-title":"Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy","volume":"17","author":"Rawlinson","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.pedneo.2025.08.016_bib22","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/INF.0b013e3181979a27","article-title":"Cytomegalovirus blood viral load and hearing loss in young children with congenital infection","volume":"28","author":"Ross","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.pedneo.2025.08.016_bib23","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000446690","article-title":"A prognostic neonatal neuroimaging scale for symptomatic congenital cytomegalovirus infection","volume":"110","author":"Alarcon","year":"2016","journal-title":"Neonatology"},{"key":"10.1016\/j.pedneo.2025.08.016_bib24","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/pd.4118","article-title":"A series of 238 cytomegalovirus primary infections during pregnancy: description and outcome","volume":"33","author":"Picone","year":"2013","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.pedneo.2025.08.016_bib25","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jcv.2005.09.015","article-title":"Congenital cytomegalovirus infection following first trimester maternal infection: symptoms at birth and outcome","volume":"35","author":"Pass","year":"2006","journal-title":"J Clin Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib26","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1471-0528.2007.01651.x","article-title":"Congenital cytomegalovirus infection following primary maternal infection in the third trimester","volume":"115","author":"Gindes","year":"2008","journal-title":"BJOG"},{"key":"10.1016\/j.pedneo.2025.08.016_bib27","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jcv.2011.07.005","article-title":"Intrauterine transmission and clinical outcome of 248 pregnancies with primary cytomegalovirus infection in relation to gestational age","volume":"52","author":"Enders","year":"2011","journal-title":"J Clin Virol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib28","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jpeds.2007.12.049","article-title":"A 10-year prospective study of sensorineural hearing loss in children with congenital cytomegalovirus infection","volume":"153","author":"Foulon","year":"2008","journal-title":"J Pediatr"},{"key":"10.1016\/j.pedneo.2025.08.016_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2025.1597001","article-title":"Congenital toxoplasmosis: an observational retrospective study in the eastern sicily","volume":"13","author":"Garozzo","year":"2025","journal-title":"Front Pediatr"},{"key":"10.1016\/j.pedneo.2025.08.016_bib30","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/cid\/ciy1128","article-title":"Sequelae of congenital cytomegalovirus following maternal primary infections are limited to those acquired in the first trimester of pregnancy","volume":"69","author":"Faure-Bardon","year":"2019","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.pedneo.2025.08.016_bib31","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/acn3.51255","article-title":"Trait impulsivity in juvenile myoclonic epilepsy","volume":"8","author":"Shakeshaft","year":"2021","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib32","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1056\/NEJM200105033441804","article-title":"Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity","volume":"344","author":"Boppana","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pedneo.2025.08.016_bib33","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1056\/NEJMoa1404599","article-title":"Valganciclovir for symptomatic congenital cytomegalovirus disease","volume":"372","author":"Kimberlin","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.pedneo.2025.08.016_bib34","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1542\/peds.2005-0629","article-title":"Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns","volume":"117","author":"Lanari","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2025.08.016_bib35","doi-asserted-by":"crossref","first-page":"F280","DOI":"10.1136\/adc.2007.119230","article-title":"Congenital cytomegalovirus: association between dried blood spot viral load and hearing loss","volume":"93","author":"Walter","year":"2008","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.pedneo.2025.08.016_bib36","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/uog.9008","article-title":"Neurodevelopment following fetal growth restriction and its relationship with antepartum parameters of placental dysfunction","volume":"37","author":"Baschat","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib37","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.brainres.2011.01.032","article-title":"Differential effects of intrauterine growth restriction on brain structure and development in preterm infants: a magnetic resonance imaging study","volume":"1382","author":"Padilla","year":"2011","journal-title":"Brain Res"},{"key":"10.1016\/j.pedneo.2025.08.016_bib38","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1542\/peds.90.6.862","article-title":"Progressive hearing loss in infants with asymptomatic congenital cytomegalovirus infection","volume":"90","author":"Williamson","year":"1992","journal-title":"Pediatrics"},{"key":"10.1016\/j.pedneo.2025.08.016_bib39","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1007\/s00247-011-2120-5","article-title":"Brain magnetic resonance findings in symptomatic congenital cytomegalovirus infection","volume":"41","author":"Manara","year":"2011","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.pedneo.2025.08.016_bib40","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.braindev.2013.04.001","article-title":"Role of cerebral ultrasound and magnetic resonance imaging in newborns with congenital cytomegalovirus infection","volume":"36","author":"Capretti","year":"2014","journal-title":"Brain Dev"},{"key":"10.1016\/j.pedneo.2025.08.016_bib41","first-page":"36","article-title":"Congenital cytomegalovirus infection","volume":"1","author":"Demmler","year":"1994","journal-title":"Semin Pediatr Neurol"},{"issue":"Suppl 4","key":"10.1016\/j.pedneo.2025.08.016_bib42","doi-asserted-by":"crossref","first-page":"S182","DOI":"10.1093\/cid\/cit609","article-title":"Congenital cytomegalovirus infection: audiologic outcome","volume":"57","author":"Fowler","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.pedneo.2025.08.016_bib43","first-page":"275","article-title":"[Accidental ethyl alcohol intoxication in a 30-day-old infant. Clinical findings and neurological follow-up]","volume":"59","author":"Palano","year":"2007","journal-title":"Minerva Pediatr"}],"container-title":["Pediatrics & Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957226000288?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1875957226000288?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T12:46:56Z","timestamp":1787575616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1875957226000288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1875957226000288"],"URL":"https:\/\/doi.org\/10.1016\/j.pedneo.2025.08.016","relation":{},"ISSN":["1875-9572"],"issn-type":[{"value":"1875-9572","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal transmission, neonatal outcomes, and predictors of adverse effects in congenital cytomegalovirus infection","name":"articletitle","label":"Article Title"},{"value":"Pediatrics & Neonatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pedneo.2025.08.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Taiwan Pediatric Association. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}