{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T02:12:39Z","timestamp":1760926359242,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2018ZX09J18105-003"],"award-info":[{"award-number":["2018ZX09J18105-003"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Protein Expression and Purification"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.pep.2023.106370","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T21:20:14Z","timestamp":1694553614000},"page":"106370","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Generation and characterization of a monoclonal antibody against FGFR3 that protects mice from BoNT\/A"],"prefix":"10.1016","volume":"213","author":[{"given":"Xianghua","family":"Xiong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujin","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinglun","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weicai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huipeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodong","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.pep.2023.106370_bib1","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1006\/jmbi.1999.2945","article-title":"Sequence homology and structural analysis of the clostridial neurotoxins","volume":"291","author":"Lacy","year":"1999","journal-title":"J. Mol. Biol."},{"issue":"2","key":"10.1016\/j.pep.2023.106370_bib2","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/infdis\/jit449","article-title":"A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins","volume":"209","author":"Barash","year":"2014","journal-title":"JID (J. Infect. Dis.)"},{"issue":"6","key":"10.1016\/j.pep.2023.106370_bib3","doi-asserted-by":"crossref","first-page":"517","DOI":"10.4161\/mabs.3.6.17621","article-title":"Antibodies for biodefense","volume":"3","author":"Froude","year":"2011","journal-title":"mAbs"},{"issue":"6442","key":"10.1016\/j.pep.2023.106370_bib4","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/365160a0","article-title":"Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25","volume":"365","author":"Blasi","year":"1993","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.pep.2023.106370_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nsb879","article-title":"Translocation of botulinum neurotoxin light chain protease through the heavy chain channel","volume":"10","author":"Koriazova","year":"2003","journal-title":"Nat. Struct. Biol."},{"issue":"4","key":"10.1016\/j.pep.2023.106370_bib6","doi-asserted-by":"crossref","first-page":"683","DOI":"10.3390\/toxins2040683","article-title":"Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells","volume":"2","author":"Popoff","year":"2010","journal-title":"Toxins"},{"issue":"1","key":"10.1016\/j.pep.2023.106370_bib7","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-87331-7","article-title":"Characterization of clostridium botulinum neurotoxin serotype A (BoNT\/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay","volume":"11","author":"James","year":"2021","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.pep.2023.106370_bib8","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1111\/j.1471-4159.2009.06093.x","article-title":"Cell entry strategy of clostridial neurotoxins","volume":"109","author":"Binz","year":"2009","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.pep.2023.106370_bib9","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1021\/jacs.6b09534","article-title":"Glycans confer specificity to the recognition of ganglioside receptors by botulinum neurotoxin A","volume":"139","author":"Hamark","year":"2017","journal-title":"J. Am. Chem. Soc."},{"issue":"8","key":"10.1016\/j.pep.2023.106370_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000129","article-title":"Crystal structure of botulinum neurotoxin type a in complex with the cell surface co-receptor GT1b - insight into the toxin-neuron interaction","volume":"4","author":"Stenmark","year":"2008","journal-title":"PLoS Pathog."},{"issue":"8","key":"10.1016\/j.pep.2023.106370_bib11","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1016\/j.febslet.2006.02.074","article-title":"The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves","volume":"580","author":"Mahrhold","year":"2006","journal-title":"FEBS Lett."},{"issue":"5","key":"10.1016\/j.pep.2023.106370_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/toxins8050154","article-title":"Botulinum neurotoxin serotype A recognizes its protein receptor SV2 by a different mechanism than botulinum neurotoxin B synaptotagmin","volume":"8","author":"Weisemann","year":"2016","journal-title":"Toxins"},{"issue":"7","key":"10.1016\/j.pep.2023.106370_bib13","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.febslet.2014.02.034","article-title":"Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A","volume":"588","author":"Strotmeier","year":"2014","journal-title":"FEBS Lett."},{"issue":"7481","key":"10.1016\/j.pep.2023.106370_bib14","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nature12732","article-title":"Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A","volume":"505","author":"Benoit","year":"2014","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.pep.2023.106370_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003369","article-title":"Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT\/A)","volume":"9","author":"Jacky","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.pep.2023.106370_bib16","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.neuro.2020.02.009","article-title":"Endocytosis, trafficking and exocytosis of intact full-length botulinum neurotoxin type a in cultured rat neurons","volume":"78","author":"Valois","year":"2020","journal-title":"Neurotoxicology"},{"issue":"7","key":"10.1016\/j.pep.2023.106370_bib17","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1021\/ac504716v","article-title":"Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F\/A)","volume":"87","author":"Kalb","year":"2015","journal-title":"Anal. Chem."},{"issue":"7","key":"10.1016\/j.pep.2023.106370_bib18","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.3390\/toxins7072354","article-title":"A highly specific monoclonal antibody for botulinum neurotoxin type A-cleaved SNAP25","volume":"7","author":"Rheaume","year":"2015","journal-title":"Toxins"},{"issue":"1","key":"10.1016\/j.pep.2023.106370_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pep.2006.04.008","article-title":"Expression and purification of recombinant human fibroblast growth factor receptor in Escherichia coli","volume":"49","author":"Ryu","year":"2006","journal-title":"Protein Expr. Purif."},{"key":"10.1016\/j.pep.2023.106370_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2020.112871","article-title":"Production and characterization of a neutralizing antibody against botulinum neurotoxin A","volume":"487","author":"Xiong","year":"2020","journal-title":"J. Immunol. Methods"},{"issue":"2","key":"10.1016\/j.pep.2023.106370_bib21","first-page":"5","article-title":"\u4eba\u7a81\u89e6\u56ca\u6ce1\u86cb\u767d2C\u5355\u514b\u9686\u6297\u4f53\u7684\u5236\u5907\u53ca\u9274\u5b9a","volume":"29","author":"\u90b1\u8bed\u8fdb","year":"2018","journal-title":"\u751f\u7269\u6280\u672f\u901a\u8baf"}],"container-title":["Protein Expression and Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046592823001419?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046592823001419?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T01:57:46Z","timestamp":1760925466000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1046592823001419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":21,"alternative-id":["S1046592823001419"],"URL":"https:\/\/doi.org\/10.1016\/j.pep.2023.106370","relation":{},"ISSN":["1046-5928"],"issn-type":[{"type":"print","value":"1046-5928"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation and characterization of a monoclonal antibody against FGFR3 that protects mice from BoNT\/A","name":"articletitle","label":"Article Title"},{"value":"Protein Expression and Purification","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pep.2023.106370","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106370"}}