{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T20:44:15Z","timestamp":1747169055047,"version":"3.40.5"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Protein Expression and Purification"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.pep.2024.106462","type":"journal-article","created":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T07:07:29Z","timestamp":1711782449000},"page":"106462","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Synthesis of BLF1-containing trimethyl chitosan nanoparticles and evaluation of its immunogenicity and protection in syrian mice by oral and subcutaneous injections"],"prefix":"10.1016","volume":"219","author":[{"given":"Ayoub","family":"fazeli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9416-3104","authenticated-orcid":false,"given":"Hosein","family":"Honari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davoud","family":"Sadeghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Bakhtiari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.pep.2024.106462_bib1","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1046\/j.1462-2920.2003.00471.x","article-title":"Diversity and significance of Burkholderia species occupying diverse ecological niches","volume":"5","author":"Coenye","year":"2003","journal-title":"Environ. Microbiol."},{"issue":"5841","key":"10.1016\/j.pep.2024.106462_bib2","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1126\/science.317.5841.1022","article-title":"Racing to defuse a bacterial time bomb","volume":"317","author":"Stone","year":"2007","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.pep.2024.106462_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2180-10-28","article-title":"Identification of tomato plant as a novel host model for Burkholderia pseudomallei","volume":"10","author":"Lee","year":"2010","journal-title":"BMC Microbiol."},{"issue":"6","key":"10.1016\/j.pep.2024.106462_bib4","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.4269\/ajtmh.2010.10-0038","article-title":"Increasing incidence of human melioidosis in Northeast Thailand","volume":"82","author":"Limmathurotsakul","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pep.2024.106462_bib5","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3389\/fmicb.2011.00198","article-title":"Development of vaccines against Burkholderia pseudomallei","volume":"2","author":"Patel","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.pep.2024.106462_bib6","series-title":"Open Forum Infectious Diseases","article-title":"Clinical epidemiology of 7126 melioidosis patients in Thailand and the implications for a national notifiable diseases surveillance system","author":"Hantrakun","year":"2019"},{"issue":"5","key":"10.1016\/j.pep.2024.106462_bib7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1751-0813.1952.tb05138.x","article-title":"Melioidosis in sheep in Queensland: description of an outbreak","volume":"28","author":"Cottew","year":"1952","journal-title":"Aust. Vet. J."},{"issue":"6057","key":"10.1016\/j.pep.2024.106462_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1126\/science.1211915","article-title":"A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A","volume":"334","author":"Cruz-Migoni","year":"2011","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.pep.2024.106462_bib9","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1042\/BST20120057","article-title":"BLF1, the first Burkholderia pseudomallei toxin, connects inhibition of host protein synthesis with melioidosis","volume":"40","author":"Hautbergue","year":"2012","journal-title":"Biochem. Soc. Trans."},{"issue":"39","key":"10.1016\/j.pep.2024.106462_bib10","doi-asserted-by":"crossref","first-page":"14240","DOI":"10.1073\/pnas.0403302101","article-title":"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei","volume":"101","author":"Holden","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"8","key":"10.1016\/j.pep.2024.106462_bib11","doi-asserted-by":"crossref","first-page":"774","DOI":"10.4161\/viru.26399","article-title":"Ribosome-inactivating proteins: Potent poisons and molecular tools","volume":"4","author":"Walsh","year":"2013","journal-title":"Virulence"},{"issue":"8","key":"10.1016\/j.pep.2024.106462_bib12","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/j.clinthera.2010.07.020","article-title":"Progress toward development of vaccines against melioidosis: a review","volume":"32","author":"Sarkar-Tyson","year":"2010","journal-title":"Clin. Therapeut."},{"key":"10.1016\/j.pep.2024.106462_bib13","first-page":"477","article-title":"Melioidosis: where do we stand in the development of an effective vaccine?","author":"Muruato","year":"2016","journal-title":"Future Medicine"},{"key":"10.1016\/j.pep.2024.106462_bib14","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jconrel.2022.11.015","article-title":"Oral vaccination using microdevices to deliver \u03b1-GalCer adjuvanted vaccine afford a mucosal immune response","volume":"353","author":"Carlsen","year":"2023","journal-title":"J. Contr. Release"},{"issue":"3","key":"10.1016\/j.pep.2024.106462_bib15","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.vaccine.2013.11.069","article-title":"Nanoparticle vaccines","volume":"32","author":"Zhao","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.pep.2024.106462_bib16","series-title":"Practical Aspects of Vaccine Development","first-page":"329","article-title":"Conventional and nontraditional delivery methods and routes of vaccine administration","author":"Diotti","year":"2022"},{"issue":"9","key":"10.1016\/j.pep.2024.106462_bib17","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1517\/17425247.2015.1018175","article-title":"Polymeric nanoparticle drug delivery technologies for oral delivery applications","volume":"12","author":"Pridgen","year":"2015","journal-title":"Expet Opin. Drug Deliv."},{"issue":"1\u20132","key":"10.1016\/j.pep.2024.106462_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0168-3659(00)00339-4","article-title":"Biodegradable polymeric nanoparticles as drug delivery devices","volume":"70","author":"Soppimath","year":"2001","journal-title":"J. Contr. Release"},{"issue":"1","key":"10.1016\/j.pep.2024.106462_bib19","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2165\/00137696-200301010-00004","article-title":"The role of chitosan in drug delivery","volume":"1","author":"Fini","year":"2003","journal-title":"Am. J. Drug Deliv."},{"issue":"4","key":"10.1016\/j.pep.2024.106462_bib20","first-page":"193","article-title":"Preparation and characterization of trimethyl chitosan nanospheres encapsulated with tetanus toxoid for nasal immunization studies","volume":"18","author":"Zarifpour","year":"2013","journal-title":"Pharmaceut. Sci."},{"issue":"2","key":"10.1016\/j.pep.2024.106462_bib21","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/prep.1998.1007","article-title":"Recombinant and truncated tetanus neurotoxin light chain: cloning, expression, purification, and proteolytic activity","volume":"15","author":"Tonello","year":"1999","journal-title":"Protein Expr. Purif."},{"issue":"3","key":"10.1016\/j.pep.2024.106462_bib22","first-page":"212","article-title":"IpaD-loaded N-trimethyl chitosan nanoparticles can efficiently protect Guinea pigs against Shigella flexneri","volume":"16","author":"Akbari","year":"2019","journal-title":"Iranian Journal of Immunology"},{"issue":"5","key":"10.1016\/j.pep.2024.106462_bib23","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/infdis\/159.5.890","article-title":"Melioidosis: a major cause of community-acquired septicemia in northeastern Thailand","volume":"159","author":"Chaowagul","year":"1989","journal-title":"JID (J. Infect. Dis.)"},{"volume":"vol. 13","year":"2001","author":"Xu","key":"10.1016\/j.pep.2024.106462_bib24"},{"key":"10.1016\/j.pep.2024.106462_bib25","doi-asserted-by":"crossref","first-page":"562","DOI":"10.3389\/fimmu.2018.00562","article-title":"Trimethyl chitosan nanoparticles encapsulated protective antigen protects the mice against anthrax","volume":"9","author":"Malik","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.pep.2024.106462_bib26","doi-asserted-by":"crossref","first-page":"8769","DOI":"10.2147\/IJN.S149774","article-title":"Oral immunization of mice with Omp31-loaded N-trimethyl chitosan nanoparticles induces high protection against Brucella melitensis infection","volume":"12","author":"Abkar","year":"2017","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.pep.2024.106462_bib27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jconrel.2018.03.013","article-title":"N-trimethyl chitosan nanoparticles and CSKSSDYQC peptide: N-trimethyl chitosan conjugates enhance the oral bioavailability of gemcitabine to treat breast cancer","volume":"277","author":"Chen","year":"2018","journal-title":"J. Contr. Release"},{"issue":"12","key":"10.1016\/j.pep.2024.106462_bib28","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1080\/21645515.2015.1053663","article-title":"Enteric trimethyl chitosan nanoparticles containing hepatitis B surface antigen for oral delivery","volume":"11","author":"Farhadian","year":"2015","journal-title":"Hum. Vaccines Immunother."},{"issue":"1\u20132","key":"10.1016\/j.pep.2024.106462_bib29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jconrel.2005.11.014","article-title":"Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system","volume":"111","author":"Amidi","year":"2006","journal-title":"J. Contr. Release"},{"issue":"7","key":"10.1016\/j.pep.2024.106462_bib30","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1021\/es60130a004","article-title":"Trimmed Spearman-Karber method for estimating median lethal concentrations in toxicity bioassays","volume":"11","author":"Hamilton","year":"1977","journal-title":"Environmental Science & Technology"}],"container-title":["Protein Expression and Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046592824000342?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046592824000342?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T20:07:57Z","timestamp":1714853277000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1046592824000342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":30,"alternative-id":["S1046592824000342"],"URL":"https:\/\/doi.org\/10.1016\/j.pep.2024.106462","relation":{},"ISSN":["1046-5928"],"issn-type":[{"type":"print","value":"1046-5928"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of BLF1-containing trimethyl chitosan nanoparticles and evaluation of its immunogenicity and protection in syrian mice by oral and subcutaneous injections","name":"articletitle","label":"Article Title"},{"value":"Protein Expression and Purification","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pep.2024.106462","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106462"}}