{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:42:36Z","timestamp":1791042156267,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Peptides"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.peptides.2011.08.003","type":"journal-article","created":{"date-parts":[[2011,8,17]],"date-time":"2011-08-17T00:55:28Z","timestamp":1313542528000},"page":"1866-1871","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat"],"prefix":"10.1016","volume":"32","author":[{"given":"Luigi","family":"Brunetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Di Nisio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Recinella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Chiavaroli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Leone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Ferrante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giustino","family":"Orlando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Vacca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.peptides.2011.08.003_bib0005","doi-asserted-by":"crossref","first-page":"4687","DOI":"10.1210\/en.2007-0175","article-title":"Chemerin is a novel adipokine associated with obesity and metabolic syndrome","volume":"148","author":"Bozaoglu","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.peptides.2011.08.003_bib0010","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1177\/039463200501800203","article-title":"The regulation of feeding: a cross talk between peripheral and central signalling","volume":"18","author":"Brunetti","year":"2005","journal-title":"Int J Immunopathol Pharmacol"},{"issue":"Suppl. 5","key":"10.1016\/j.peptides.2011.08.003_bib0015","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1038\/sj.ijo.0801913","article-title":"The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis","volume":"25","author":"Cone","year":"2001","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.peptides.2011.08.003_bib0020","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.febslet.2008.03.037","article-title":"AdipoR1 mediates the anorexigenic and insulin\/leptin-like actions of adiponectin in the hypothalamus","volume":"582","author":"Coope","year":"2008","journal-title":"FEBS Lett"},{"key":"10.1016\/j.peptides.2011.08.003_bib0025","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/glia.10181","article-title":"Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation","volume":"41","author":"Croitoru-Lamoury","year":"2003","journal-title":"Glia"},{"key":"10.1016\/j.peptides.2011.08.003_bib0030","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.2337\/db06-1506","article-title":"Omentin plasma levels and gene expression are decreased in obesity","volume":"56","author":"de Souza Batista","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.peptides.2011.08.003_bib0035","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/abbs\/gmp091","article-title":"Proteolytic regulatory mechanism of chemerin bioactivity","volume":"41","author":"Du","year":"2009","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"10.1016\/j.peptides.2011.08.003_bib0040","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0896-6273(00)80656-X","article-title":"Leptin activates hypothalamic CART neurons projecting to the spinal cord","volume":"21","author":"Elias","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.peptides.2011.08.003_bib0045","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1210\/en.2009-1098","article-title":"Chemerin exacerbates glucose intolerance in mouse models of obesity and diabetes","volume":"151","author":"Ernst","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.peptides.2011.08.003_bib0050","doi-asserted-by":"crossref","first-page":"9603","DOI":"10.1073\/pnas.92.21.9603","article-title":"Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease","volume":"92","author":"Faucheux","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.peptides.2011.08.003_bib0055","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1179\/016164104225017622","article-title":"The evolution of omentum transposition: from lymphedema to spinal cord, stroke and Alzheimer's disease","volume":"26","author":"Goldsmith","year":"2004","journal-title":"Neurol Res"},{"key":"10.1016\/j.peptides.2011.08.003_bib0060","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1113\/jphysiol.2009.172510","article-title":"Regulation of visceral adipose tissue-derived serine protease inhibitor by nutritional status, metformin, gender and pituitary factors in rat white adipose tissue","volume":"587","author":"Gonz\u00e1lez","year":"2009","journal-title":"J Physiol"},{"key":"10.1016\/j.peptides.2011.08.003_bib0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/1082","article-title":"Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons","volume":"1","author":"Hahn","year":"1998","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.peptides.2011.08.003_bib0070","doi-asserted-by":"crossref","first-page":"10610","DOI":"10.1073\/pnas.0504703102","article-title":"Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity","volume":"102","author":"Hida","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.peptides.2011.08.003_bib0075","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1172\/JCI29126","article-title":"Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome","volume":"116","author":"Kadowaki","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.peptides.2011.08.003_bib0080","first-page":"68","article-title":"Interacting appetite-regulating pathways in the hypothalamic regulation of body weight","volume":"20","author":"Kalra","year":"1999","journal-title":"Endocr Rev"},{"key":"10.1016\/j.peptides.2011.08.003_bib0085","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1385\/ENDO:22:1:49","article-title":"Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin","volume":"22","author":"Kalra","year":"2003","journal-title":"Endocrine"},{"key":"10.1016\/j.peptides.2011.08.003_bib0090","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.2337\/diab.41.11.1422","article-title":"Spontaneous long-term hyperglycemic rat with diabetic complications Otsuka Long-Evans Tokushima Fatty (OLETF) strain","volume":"41","author":"Kawano","year":"1992","journal-title":"Diabetes"},{"key":"10.1016\/j.peptides.2011.08.003_bib0095","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.bbrc.2005.11.039","article-title":"Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes","volume":"339","author":"Kl\u00f6ting","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.peptides.2011.08.003_bib0100","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.peptides.2011.08.003_bib0105","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1743-7075-7-27","article-title":"Circulating omentin concentration increases after weight loss","volume":"7","author":"Moreno-Navarrete","year":"2010","journal-title":"Nutr Metab"},{"key":"10.1016\/j.peptides.2011.08.003_bib0110","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.cmet.2005.10.009","article-title":"Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons","volume":"2","author":"Morton","year":"2005","journal-title":"Cell Metab"},{"key":"10.1016\/j.peptides.2011.08.003_bib0115","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2007"},{"key":"10.1016\/j.peptides.2011.08.003_bib0120","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s002219900289","article-title":"A second look at the barriers of the medial basal hypothalamus","volume":"132","author":"Peruzzo","year":"2000","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.peptides.2011.08.003_bib0125","doi-asserted-by":"crossref","first-page":"741","DOI":"10.2119\/2008-00058.Rabe","article-title":"Adipokines and insulin resistance","volume":"14","author":"Rabe","year":"2008","journal-title":"Mol Med"},{"key":"10.1016\/j.peptides.2011.08.003_bib0130","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neulet.2010.05.018","article-title":"A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus","volume":"479","author":"Sahu","year":"2010","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.peptides.2011.08.003_bib0135","doi-asserted-by":"crossref","first-page":"R1293","DOI":"10.1152\/ajpregu.90948.2008","article-title":"Phosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax)","volume":"296","author":"S\u00e1nchez","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.peptides.2011.08.003_bib0140","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3940(97)00163-8","article-title":"The arcuate nucleus as a primary site of satiety effect of leptin in rats","volume":"224","author":"Satoh","year":"1997","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.peptides.2011.08.003_bib0145","doi-asserted-by":"crossref","first-page":"531","DOI":"10.2337\/diab.45.4.531","article-title":"Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob\/ob mice","volume":"45","author":"Schwartz","year":"1996","journal-title":"Diabetes"},{"key":"10.1016\/j.peptides.2011.08.003_bib0150","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.2337\/diab.46.12.2119","article-title":"Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus","volume":"46","author":"Schwartz","year":"1997","journal-title":"Diabetes"},{"key":"10.1016\/j.peptides.2011.08.003_bib0155","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/35007534","article-title":"Central nervous system control of food intake","volume":"404","author":"Schwartz","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.peptides.2011.08.003_bib0160","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1210\/jc.2007-1853","article-title":"Serum levels of the adipokine vaspin in relation to metabolic and renal parameters","volume":"93","author":"Seeger","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.peptides.2011.08.003_bib0165","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/377530a0","article-title":"The role of neuropeptide Y in the antiobesity action of the obese gene product","volume":"377","author":"Stephens","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.peptides.2011.08.003_bib0170","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1210\/en.2004-1397","article-title":"Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y\/agouti-related protein neurons","volume":"146","author":"Takahashi","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.peptides.2011.08.003_bib0175","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.febslet.2008.01.023","article-title":"Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes","volume":"582","author":"Takahashi","year":"2008","journal-title":"FEBS Lett"},{"key":"10.1016\/j.peptides.2011.08.003_bib0180","first-page":"783","article-title":"Binding characteristics and distribution of lactoferrin receptors in the gut and choroid plexus in newborn calves","volume":"44","author":"Talukder","year":"2006","journal-title":"Indian J Exp Biol"},{"key":"10.1016\/j.peptides.2011.08.003_bib0185","doi-asserted-by":"crossref","first-page":"5063","DOI":"10.1210\/endo.138.11.5651","article-title":"Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob\/ob mice","volume":"138","author":"Thornton","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.peptides.2011.08.003_bib0190","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1210\/er.2006-0033","article-title":"Adipose tissue-derived factors: impact on health and disease","volume":"27","author":"Trujillo","year":"2006","journal-title":"Endocr Rev"},{"key":"10.1016\/j.peptides.2011.08.003_bib0195","doi-asserted-by":"crossref","first-page":"23456","DOI":"10.1074\/jbc.M103162200","article-title":"Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall","volume":"276","author":"Tsuji","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.peptides.2011.08.003_bib0200","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1084\/jem.20030382","article-title":"Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids","volume":"198","author":"Wittamer","year":"2003","journal-title":"J Exp Med"},{"key":"10.1016\/j.peptides.2011.08.003_bib0205","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/S0899-9007(00)00454-8","article-title":"Adiposity signals and the control of energy homeostasis","volume":"16","author":"Woods","year":"2000","journal-title":"Nutrition"},{"key":"10.1016\/j.peptides.2011.08.003_bib0210","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1152\/ajpendo.00572.2004","article-title":"Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action","volume":"290","author":"Yang","year":"2006","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.peptides.2011.08.003_bib0215","doi-asserted-by":"crossref","first-page":"372","DOI":"10.2337\/db07-1045","article-title":"Serum vaspin concentrations in human obesity and type 2 diabetes","volume":"57","author":"Youn","year":"2008","journal-title":"Diabetes"}],"container-title":["Peptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196978111003226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196978111003226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T09:21:33Z","timestamp":1759310493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196978111003226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":43,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0196978111003226"],"URL":"https:\/\/doi.org\/10.1016\/j.peptides.2011.08.003","relation":{},"ISSN":["0196-9781"],"issn-type":[{"value":"0196-9781","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat","name":"articletitle","label":"Article Title"},{"value":"Peptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.peptides.2011.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}