{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:36:15Z","timestamp":1793370975916,"version":"4.5.0"},"reference-count":141,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Peptides"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.peptides.2020.170389","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T21:53:57Z","timestamp":1598478837000},"page":"170389","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Estrogen and gut satiety hormones in vagus-hindbrain axis"],"prefix":"10.1016","volume":"133","author":[{"given":"Kuei-Pin","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen E.","family":"Raybould","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.peptides.2020.170389_bib0005","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/ejcn.2014.86","article-title":"Global differences between women and men in the prevalence of obesity: is there an association with gender inequality?","volume":"68","author":"Garawi","year":"2014","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.peptides.2020.170389_bib0010","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1093\/ajcn\/49.2.252","article-title":"Menstrual cycle and voluntary food intake","volume":"49","author":"Gong","year":"1989","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.peptides.2020.170389_bib0015","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1093\/ajcn\/49.6.1164","article-title":"Reduction of food intake in the ovulatory phase of the menstrual cycle","volume":"49","author":"Lyons","year":"1989","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.peptides.2020.170389_bib0020","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/ajcn\/57.1.43","article-title":"Changes in dietary intake, urinary nitrogen, and urinary volume across the menstrual cycle","volume":"57","author":"Fong","year":"1993","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.peptides.2020.170389_bib0025","doi-asserted-by":"crossref","first-page":"3312","DOI":"10.1210\/jc.2004-1344","article-title":"Sex hormone suppression reduces resting energy expenditure and {beta}-adrenergic support of resting energy expenditure","volume":"90","author":"Day","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0030","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0960-0760(03)00360-1","article-title":"Sources of estrogen and their importance","volume":"86","author":"Simpson","year":"2003","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.peptides.2020.170389_bib0035","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1006\/hbeh.2002.1835","article-title":"Cyclic estradiol treatment normalizes body weight and restores physiological patterns of spontaneous feeding and sexual receptivity in ovariectomized rats","volume":"42","author":"Asarian","year":"2002","journal-title":"Horm. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0040","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/ijo.2008.25","article-title":"Increased visceral fat and decreased energy expenditure during the menopausal transition","volume":"32","author":"Lovejoy","year":"2008","journal-title":"Int. J. Obes. (Lond)."},{"key":"10.1016\/j.peptides.2020.170389_bib0045","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1210\/en.2008-1405","article-title":"Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity","volume":"150","author":"Rogers","year":"2009","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0050","doi-asserted-by":"crossref","first-page":"12735","DOI":"10.1073\/pnas.97.23.12735","article-title":"Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity","volume":"97","author":"Jones","year":"2000","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.peptides.2020.170389_bib0055","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/oby.2009.273","article-title":"Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice","volume":"18","author":"Hwang","year":"2010","journal-title":"Obesity."},{"key":"10.1016\/j.peptides.2020.170389_bib0060","doi-asserted-by":"crossref","first-page":"e46057","DOI":"10.1371\/journal.pone.0046057","article-title":"Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory t cell population in adipose tissue","volume":"7","author":"Pettersson","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.peptides.2020.170389_bib0065","doi-asserted-by":"crossref","first-page":"e261","DOI":"10.1038\/nutd.2017.6","article-title":"The role of sex and body weight on the metabolic effects of high-fat diet in C57BL\/6N mice","volume":"7","author":"Ingvorsen","year":"2017","journal-title":"Nutr. Diabetes"},{"key":"10.1016\/j.peptides.2020.170389_bib0070","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3389\/fphys.2017.00032","article-title":"Long term high fat diet treatment: an appropriate approach to study the sex-specificity of the autonomic and cardiovascular responses to obesity in mice","volume":"8","author":"Bruder-Nascimento","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0075","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13293-018-0208-4","article-title":"Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice","volume":"9","author":"Paruthiyil","year":"2018","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.peptides.2020.170389_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.112894","article-title":"Sex differences in response to short-term high fat diet in mice","author":"Huang","year":"2020","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0085","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1210\/er.2012-1055","article-title":"The role of estrogens in control of energy balance and glucose homeostasis","volume":"34","author":"Mauvais-Jarvis","year":"2013","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.peptides.2020.170389_bib0090","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.tem.2015.06.003","article-title":"Estrogens and the control of energy homeostasis: a brain perspective","volume":"26","author":"L\u00f3pez","year":"2015","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0095","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1093\/humupd\/dmw045","article-title":"Ovarian hormones and obesity","volume":"23","author":"Leeners","year":"2017","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.peptides.2020.170389_bib0100","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.97.23.12729","article-title":"Increased adipose tissue in male and female estrogen receptor-\u03b1 knockout mice","volume":"97","author":"Heine","year":"2000","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.peptides.2020.170389_bib0105","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1210\/endo.142.11.8504","article-title":"Deficits in E2-Dependent control of feeding, weight gain, and cholecystokinin satiation in ER-\u03b1 null mice","volume":"142","author":"Geary","year":"2001","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0110","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1006\/bbrc.2000.3827","article-title":"Obesity and disturbed lipoprotein profile in estrogen Receptor-\u03b1-Deficient male mice","volume":"278","author":"Ohlsson","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.peptides.2020.170389_bib0115","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1359\/jbmr.2001.16.8.1388","article-title":"Female estrogen receptor \u03b2\u2212\/\u2212 mice are partially protected against age-related trabecular bone loss","volume":"16","author":"Windahl","year":"2001","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0120","article-title":"Metabolic actions of estrogen receptor Beta (ER\u03b2) are mediated by a negative cross-talk with PPAR\u03b3","volume":"4","author":"Ludwig","year":"2008","journal-title":"PLoS Genet."},{"key":"10.1016\/j.peptides.2020.170389_bib0125","doi-asserted-by":"crossref","first-page":"31292","DOI":"10.1074\/jbc.M110.147850","article-title":"Estrogen Receptor-\u03b2-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice","volume":"285","author":"Yepuru","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.peptides.2020.170389_bib0130","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.yfrne.2009.04.011","article-title":"Membrane estradiol signaling in the brain","volume":"30","author":"Micevych","year":"2009","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.peptides.2020.170389_bib0135","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.yhbeh.2018.03.001","article-title":"Interactions between estrogen receptors and metabotropic glutamate receptors and their impact on drug addiction in females","volume":"104","author":"Tonn Eisinger","year":"2018","journal-title":"Horm. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0140","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1152\/physrev.00024.2016","article-title":"Membrane and nuclear estrogen receptor alpha actions: from tissue specificity to medical implications","volume":"97","author":"Arnal","year":"2017","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.peptides.2020.170389_bib0145","doi-asserted-by":"crossref","DOI":"10.2337\/db17-1342","article-title":"Membrane-initiated estrogen receptor signaling mediates metabolic homeostasis via central activation of protein phosphatase 2A","volume":"67","author":"Ueda","year":"2018","journal-title":"Diabetes."},{"key":"10.1016\/j.peptides.2020.170389_bib0150","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev.physiol.70.113006.100518","article-title":"Estrogen Signaling through the Transmembrane G Protein\u2013Coupled Receptor GPR30","volume":"70","author":"Prossnitz","year":"2008","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0155","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1210\/en.2008-0623","article-title":"Deletion of the g protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice","volume":"150","author":"M\u00e5rtensson","year":"2009","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0160","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1095\/biolreprod.108.071175","article-title":"GPR30 does not mediate estrogenic responses in reproductive organs in mice","volume":"80","author":"Otto","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.peptides.2020.170389_bib0165","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1210\/en.2008-1488","article-title":"expression pattern of g protein-coupled receptor 30 in LacZ reporter mice","volume":"150","author":"Isensee","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.peptides.2020.170389_bib0170","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.yhbeh.2014.09.001","article-title":"GPER1 (GPR30) knockout mice display reduced anxiety and altered stress response in a sex and paradigm dependent manner","volume":"66","author":"Kastenberger","year":"2014","journal-title":"Horm. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0175","doi-asserted-by":"crossref","first-page":"34302","DOI":"10.1038\/srep34302","article-title":"GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro","volume":"6","author":"Wang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.peptides.2020.170389_bib0180","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1161\/CIRCRESAHA.108.190892","article-title":"Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity","volume":"104","author":"Haas","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0185","doi-asserted-by":"crossref","first-page":"4136","DOI":"10.1210\/en.2013-1357","article-title":"GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state","volume":"154","author":"Sharma","year":"2013","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0190","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.yhbeh.2014.02.004","article-title":"Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis","volume":"66","author":"Davis","year":"2014","journal-title":"Horm. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0195","doi-asserted-by":"crossref","first-page":"eaau5956","DOI":"10.1126\/scitranslmed.aau5956","article-title":"Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes","volume":"12","author":"Sharma","year":"2020","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.peptides.2020.170389_bib0200","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.cell.2015.03.022","article-title":"Vagal sensory neuron subtypes that differentially control breathing","volume":"161","author":"Chang","year":"2015","journal-title":"Cell."},{"key":"10.1016\/j.peptides.2020.170389_bib0205","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.cell.2016.05.011","article-title":"Sensory neurons that detect stretch and nutrients in the digestive system","volume":"166","author":"Williams","year":"2016","journal-title":"Cell."},{"key":"10.1016\/j.peptides.2020.170389_bib0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2019.10.031","article-title":"Genetic identification of vagal sensory neurons that control feeding","volume":"179","author":"Bai","year":"2019","journal-title":"Cell."},{"key":"10.1016\/j.peptides.2020.170389_bib0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2019.04.096","article-title":"An atlas of vagal sensory neurons and their molecular specialization","volume":"27","author":"Kupari","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.peptides.2020.170389_bib0220","first-page":"431","article-title":"Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat","volume":"530","author":"Zhu","year":"2001","journal-title":"J. Physiol. (Paris)"},{"key":"10.1016\/j.peptides.2020.170389_bib0225","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/nrgastro.2013.29","article-title":"Extrinsic primary afferent signalling in the gut","volume":"10","author":"Brookes","year":"2013","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.peptides.2020.170389_bib0230","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1152\/physrev.00039.2015","article-title":"Vagal afferent innervation of the airways in health and disease","volume":"96","author":"Mazzone","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.peptides.2020.170389_bib0235","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/s41575-018-0062-1","article-title":"The metabolic role of vagal afferent innervation","volume":"15","author":"Waise","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.peptides.2020.170389_bib0240","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0006-8993(91)90562-A","article-title":"Excitatory effects of cholecystokinin octapeptide on rat nodose ganglion cells in vitro","volume":"556","author":"Dun","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0245","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2982.2009.01430.x","article-title":"Glucagon-like peptide-1 inhibits voltage-gated potassium currents in mouse nodose ganglion neurons","volume":"22","author":"Gaisano","year":"2010","journal-title":"Neurogastroenterol. Motil."},{"key":"10.1016\/j.peptides.2020.170389_bib0250","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1210\/en.2004-1266","article-title":"The role of the vagal nerve in peripheral PYY3\u201336-Induced feeding reduction in rats","volume":"146","author":"Koda","year":"2005","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0255","doi-asserted-by":"crossref","first-page":"C427","DOI":"10.1152\/ajpcell.00439.2005","article-title":"Leptin and CCK modulate complementary background conductances to depolarize cultured nodose neurons","volume":"290","author":"Peters","year":"2006","journal-title":"Am. J. Physiol. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0260","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.physbeh.2014.03.011","article-title":"Putative roles of neuropeptides in vagal afferent signaling","volume":"136","author":"deLartigue","year":"2014","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.01.045","article-title":"Blunted vagal cocaine- and amphetamine-regulated transcript promotes hyperphagia and weight gain","volume":"30","author":"Lee","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.peptides.2020.170389_bib0270","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.cmet.2012.06.015","article-title":"Hindbrain neurons as an essential hub in the neuroanatomically distributed control of energy balance","volume":"16","author":"Grill","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0275","first-page":"A92","article-title":"OP291 modulation of gastric vagal afferent satiety signals by the mouse oesterus cycle and 17B-oestradiol: UEG week","author":"Kentish","year":"2014","journal-title":"2014 Oral Presentations, United Eur. Gastroenterol. Conf."},{"key":"10.1016\/j.peptides.2020.170389_bib0280","doi-asserted-by":"crossref","first-page":"E568","DOI":"10.1152\/ajpendo.00296.2018","article-title":"Deletion of leptin receptors in vagal afferent neurons disrupts estrogen signaling, body weight, food intake and hormonal controls of feeding in female mice","volume":"316","author":"Huang","year":"2019","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2016.01.041","article-title":"Effect of estrogen on vagal afferent projections to the brainstem in the female","volume":"1636","author":"Ciriello","year":"2016","journal-title":"Brain Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0290","doi-asserted-by":"crossref","first-page":"C654","DOI":"10.1152\/ajpcell.00059.2009","article-title":"17\u03b2-Estradiol restores excitability of a sexually dimorphic subset of myelinated vagal afferents in ovariectomized rats","volume":"297","author":"Qiao","year":"2009","journal-title":"Am. J. Physiol. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0295","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2006.09.035","article-title":"Sex-specific densities of estrogen receptors alpha and beta in the subnuclei of the nucleus tractus solitarius, hypoglossal nucleus and dorsal vagal motor nucleus weanling rats","volume":"1123","author":"Schlenker","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0300","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1210\/en.2007-0340","article-title":"Hindbrain administration of estradiol inhibits feeding and activates estrogen Receptor-\u03b1-Expressing cells in the nucleus tractus solitarius of ovariectomized rats","volume":"149","author":"Thammacharoen","year":"2008","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0305","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s11062-017-9631-0","article-title":"Effects of hindbrain infusion of an estrogen receptor antagonist on estrogenic modulation of eating behavior","volume":"49","author":"Thammacharoen","year":"2017","journal-title":"Neurophysiology."},{"key":"10.1016\/j.peptides.2020.170389_bib0310","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1152\/physrev.00014.2005","article-title":"Cholecystokinin and gastrin receptors","volume":"86","author":"Dufresne","year":"2006","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.peptides.2020.170389_bib0315","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/245323a0","article-title":"Cholecystokinin elicits satiety in rats with open gastric fistulas","volume":"245","author":"GIBBS","year":"1973","journal-title":"Nature."},{"key":"10.1016\/j.peptides.2020.170389_bib0320","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1126\/science.7268408","article-title":"Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat","volume":"213","author":"Smith","year":"1981","journal-title":"Science (80-.)"},{"key":"10.1016\/j.peptides.2020.170389_bib0325","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000147837","article-title":"Anatomical relationship between vagal afferent fibers and CCK-Immunoreactive entero-endocrine cells in the rat small intestinal mucosa","volume":"156","author":"Berthoud","year":"1996","journal-title":"Cells Tissues Organs (Print)"},{"key":"10.1016\/j.peptides.2020.170389_bib0330","doi-asserted-by":"crossref","first-page":"R972","DOI":"10.1152\/ajpregu.1993.264.5.R972","article-title":"Suppression of sham feeding by intraintestinal nutrients is not correlated with plasma cholecystokinin elevation","volume":"264","author":"Brenner","year":"1993","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0335","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/S0016-5085(99)70399-9","article-title":"Expression of cholecystokinin a receptors in neurons innervating the rat stomach and intestine","volume":"117","author":"Sternini","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.peptides.2020.170389_bib0340","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/ar.10026","article-title":"Vagal afferents innervating the gastrointestinal tract and CCKA-receptor immunoreactivity","volume":"266","author":"Patterson","year":"2002","journal-title":"Anat. Rec."},{"key":"10.1016\/j.peptides.2020.170389_bib0345","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/55.1.291s","article-title":"CCK antagonists and CCK-monoamine interactions in the control of satiety","volume":"55","author":"Cooper","year":"1992","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.peptides.2020.170389_bib0350","doi-asserted-by":"crossref","first-page":"R1005","DOI":"10.1152\/ajpregu.00646.2003","article-title":"Abdominal vagal mediation of the satiety effects of CCK in rats","volume":"286","author":"Reidelberger","year":"2004","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0355","first-page":"G1002","article-title":"Characterization of CCKA receptor affinity states and Ca2+ signal transduction in vagal nodose ganglia","volume":"282","author":"Lankisch","year":"2002","journal-title":"Am. J. Physiol. Liver Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0360","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.22-15-06380.2002","article-title":"Cholecystokinin tunes firing of an electrically distinct subset of arcuate nucleus neurons by activating A-Type potassium channels","volume":"22","author":"Burdakov","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.peptides.2020.170389_bib0365","doi-asserted-by":"crossref","first-page":"5237","DOI":"10.1210\/en.2010-0504","article-title":"Role of transient receptor potential channels in cholecystokinin-induced activation of cultured vagal afferent neurons","volume":"151","author":"Zhao","year":"2010","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0370","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.122058","article-title":"TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons","volume":"4","author":"Wang","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.peptides.2020.170389_bib0375","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/0196-9781(94)90050-7","article-title":"Cholecystokinin and estradiol synergistically potentiate satiety in rats","volume":"15","author":"Dulawa","year":"1994","journal-title":"Peptides."},{"key":"10.1016\/j.peptides.2020.170389_bib0380","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/j.1365-2826.1990.tb00643.x","article-title":"Involvement of Cholecystokinin in food intake: III. Oestradiol potentiates the inhibitory effect of cholecystokinin octapeptide on food intake in ovariectomized rats","volume":"2","author":"Lind\u00e9n","year":"1990","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.peptides.2020.170389_bib0385","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0031-9384(93)90387-U","article-title":"Modulation of the satiety effect of cholecystokinin by estradiol","volume":"53","author":"Butera","year":"1993","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0390","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0031-9384(94)90196-1","article-title":"Cyclic estradiol replacement increases the satiety effect of CCK-8 in ovariectomized rats","volume":"56","author":"Geary","year":"1994","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0395","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0196-9781(99)00025-X","article-title":"Endogenous cholecystokinin\u2019s satiating action increases during estrus in female rats","volume":"20","author":"Eckel","year":"1999","journal-title":"Peptides."},{"key":"10.1016\/j.peptides.2020.170389_bib0400","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0196-9781(99)00024-8","article-title":"Cyclic estradiol treatment phasically potentiates endogenous cholecystokinin\u2019s satiating action in ovariectomized rats","volume":"20","author":"Asarian","year":"1999","journal-title":"Peptides."},{"key":"10.1016\/j.peptides.2020.170389_bib0405","doi-asserted-by":"crossref","first-page":"5656","DOI":"10.1210\/en.2007-0341","article-title":"Estradiol enhances cholecystokinin-dependent lipid-induced satiation and activates estrogen Receptor-\u03b1-Expressing cells in the nucleus tractus solitarius of ovariectomized rats","volume":"148","author":"Asarian","year":"2007","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0410","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.neuroscience.2017.06.049","article-title":"A tale of two circuits: CCKNTS neuron stimulation controls appetite and induces opposing motivational states by projections to distinct brain regions","volume":"358","author":"Roman","year":"2017","journal-title":"Neuroscience."},{"key":"10.1016\/j.peptides.2020.170389_bib0415","doi-asserted-by":"crossref","first-page":"e12225","DOI":"10.7554\/eLife.12225","article-title":"Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit","volume":"5","author":"Agostino","year":"2016","journal-title":"Elife."},{"key":"10.1016\/j.peptides.2020.170389_bib0420","doi-asserted-by":"crossref","first-page":"11905","DOI":"10.1038\/ncomms11905","article-title":"Genetically and functionally defined NTS to PBN brain circuits mediating anorexia","volume":"7","author":"Roman","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.peptides.2020.170389_bib0425","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1037\/0735-7044.110.4.823","article-title":"Central implants of dilute estradiol enhance the satiety effect of CCK-8","volume":"110","author":"Butera","year":"1996","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.peptides.2020.170389_bib0430","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5115\/acb.2012.45.1.1","article-title":"A review on gastric leptin: the exocrine secretion of a gastric hormone","volume":"45","author":"Cammisotto","year":"2012","journal-title":"Anat. Cell Biol."},{"key":"10.1016\/j.peptides.2020.170389_bib0435","doi-asserted-by":"crossref","DOI":"10.1530\/JOE-14-0404","article-title":"20 YEARS OF LEPTIN: connecting leptin signaling to biological function","volume":"223","author":"Allison","year":"2014","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.peptides.2020.170389_bib0440","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/nrd3757","article-title":"Leptin revisited: its mechanism of action and potential for treating diabetes","volume":"11","author":"Coppari","year":"2012","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.peptides.2020.170389_bib0445","doi-asserted-by":"crossref","DOI":"10.1038\/nrn.2017.168","article-title":"Leptin and the maintenance of elevated body weight","volume":"19","author":"Pan","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.peptides.2020.170389_bib0450","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1210\/endo.143.1.8589","article-title":"Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake","volume":"143","author":"Grill","year":"2002","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0455","first-page":"E496","article-title":"Endogenous leptin receptor signaling in the medial nucleus tractus solitarius affects meal size and potentiates intestinal satiation signals","volume":"303","author":"Kanoski","year":"2012","journal-title":"Am. J. Physiol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0460","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.cmet.2009.10.009","article-title":"Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation","volume":"11","author":"Hayes","year":"2010","journal-title":"Cell Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0465","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3940(02)00023-X","article-title":"Leptin receptor expression in nodose ganglion cells projecting to the rat gastric fundus","volume":"320","author":"Peiser","year":"2002","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.peptides.2020.170389_bib0470","doi-asserted-by":"crossref","first-page":"R1544","DOI":"10.1152\/ajpregu.00811.2005","article-title":"Leptin and CCK selectively activate vagal afferent neurons innervating the stomach and duodenum","volume":"290","author":"Peters","year":"2006","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0475","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.molmet.2014.06.003","article-title":"Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity","volume":"3","author":"deLartigue","year":"2014","journal-title":"Mol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0480","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.cmet.2006.06.010","article-title":"Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells","volume":"4","author":"Kievit","year":"2006","journal-title":"Cell Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0485","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.physbeh.2014.10.032","article-title":"Chronic exposure to Low dose bacterial lipopolysaccharide inhibits leptin signaling in vagal afferent neurons","volume":"139","author":"deLa Serre","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.peptides.2020.170389_bib0490","first-page":"E291","article-title":"HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms","volume":"296","author":"White","year":"2009","journal-title":"Am. J. Physiol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0495","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.cmet.2011.09.011","article-title":"Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance","volume":"14","author":"Loh","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0500","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.1210\/en.2004-0726","article-title":"Region-specific leptin resistance within the hypothalamus of diet-induced obese mice","volume":"145","author":"M\u00fcnzberg","year":"2004","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0505","doi-asserted-by":"crossref","first-page":"e32967","DOI":"10.1371\/journal.pone.0032967","article-title":"Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats","volume":"7","author":"deLartigue","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.peptides.2020.170389_bib0510","doi-asserted-by":"crossref","first-page":"R186","DOI":"10.1152\/ajpregu.1998.275.1.R186","article-title":"Chronic administration of OB protein decreases food intake by selectively reducing meal size in female rats","volume":"275","author":"Eckel","year":"1998","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0515","first-page":"E955","article-title":"Does estradiol mediate leptin\u2019s effects on adiposity and body weight?","volume":"276","author":"Pelleymounter","year":"1999","journal-title":"Am. J. Physiol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0520","first-page":"E315","article-title":"Increased weight gain after ovariectomy is not a consequence of leptin resistance","volume":"280","author":"Chen","year":"2001","journal-title":"Am. J. Physiol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0525","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1080\/09168451.2015.1018123","article-title":"The daidzein- and estradiol- induced anorectic action in CCK or leptin receptor deficiency rats","volume":"79","author":"Fujitani","year":"2015","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.peptides.2020.170389_bib0530","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1210\/en.2015-1594","article-title":"Leptin signaling is not required for anorexigenic estradiol effects in female mice","volume":"157","author":"Kim","year":"2016","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0535","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nm1525","article-title":"Anorectic estrogen mimics leptin\u2019s effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals","volume":"13","author":"Gao","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.peptides.2020.170389_bib0540","doi-asserted-by":"crossref","first-page":"E817","DOI":"10.1152\/ajpendo.00733.2007","article-title":"Cross-talk between estrogen and leptin signaling in the hypothalamus","volume":"294","author":"Gao","year":"2008","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0545","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/j.metabol.2014.07.015","article-title":"GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus","volume":"63","author":"Kwon","year":"2014","journal-title":"Metabolism"},{"key":"10.1016\/j.peptides.2020.170389_bib0550","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1038\/sj.ijo.0801806","article-title":"Estrogen deficiency causes central leptin insensitivity and increased hypothalamic neuropeptide Y","volume":"25","author":"Ainslie","year":"2001","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.peptides.2020.170389_bib0555","doi-asserted-by":"crossref","DOI":"10.2337\/diabetes.52.3.682","article-title":"Differential sensitivity to central leptin and insulin in male and female rats","volume":"52","author":"Clegg","year":"2003","journal-title":"Diabetes."},{"key":"10.1016\/j.peptides.2020.170389_bib0560","doi-asserted-by":"crossref","first-page":"978","DOI":"10.2337\/diabetes.55.04.06.db05-1339","article-title":"Gonadal hormones determine sensitivity to central leptin and insulin","volume":"55","author":"Clegg","year":"2006","journal-title":"Diabetes."},{"key":"10.1016\/j.peptides.2020.170389_bib0565","doi-asserted-by":"crossref","first-page":"4447","DOI":"10.1210\/en.2014-1342","article-title":"Estradiol prevents fat accumulation and overcomes leptin resistance in female high-fat diet mice","volume":"155","author":"Litwak","year":"2014","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0570","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1210\/en.2004-0129","article-title":"Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats","volume":"145","author":"Meli","year":"2004","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0575","first-page":"328","article-title":"Physiologic estradiol levels enhance hypothalamic expression of the long form of the leptin receptor in intact rats, J. Nutr","volume":"15","author":"Rocha","year":"2004","journal-title":"Biochem."},{"key":"10.1016\/j.peptides.2020.170389_bib0580","doi-asserted-by":"crossref","DOI":"10.1128\/MCB.06712-11","article-title":"Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals","volume":"32","author":"He","year":"2012","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.peptides.2020.170389_bib0585","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1152\/physrev.00034.2006","article-title":"The physiology of glucagon-like peptide 1","volume":"87","author":"Holst","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.peptides.2020.170389_bib0590","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1385\/JMN:18:1-2:07","article-title":"Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier","volume":"18","author":"Kastin","year":"2002","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.peptides.2020.170389_bib0595","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/sj.ijo.0802206","article-title":"Entry of exendin-4 into brain is rapid but may be limited at high doses","volume":"27","author":"Kastin","year":"2003","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.peptides.2020.170389_bib0600","doi-asserted-by":"crossref","DOI":"10.2337\/db18-0729","article-title":"Preproglucagon neurons in the nucleus of the solitary tract are the main source of brain GLP-1, mediate stress-induced hypophagia, and limit unusually large intakes of food","volume":"68","author":"Holt","year":"2019","journal-title":"Diabetes."},{"key":"10.1016\/j.peptides.2020.170389_bib0605","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1016\/j.celrep.2019.05.055","article-title":"Distinct neural sites of GLP-1R expression mediate physiological versus pharmacological control of incretin action","volume":"27","author":"Varin","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.peptides.2020.170389_bib0610","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2005.03.011","article-title":"The inhibitory effects of peripheral administration of peptide YY3\u201336 and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal\u2013brainstem\u2013hypothalamic pathway","volume":"1044","author":"Abbott","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.peptides.2020.170389_bib0615","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41467-017-02488-y","article-title":"GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose","volume":"9","author":"Iwasaki","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.peptides.2020.170389_bib0620","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1210\/en.2005-0473","article-title":"Peripheral Exendin-4 and peptide YY3\u201336 synergistically reduce food intake through different mechanisms in mice","volume":"146","author":"Talsania","year":"2005","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0625","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1210\/en.2008-1221","article-title":"Intrameal hepatic portal and intraperitoneal infusions of glucagon-like Peptide-1 reduce spontaneous meal size in the rat via different mechanisms","volume":"150","author":"R\u00fcttimann","year":"2009","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0630","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1111\/j.1365-2826.2012.02364.x","article-title":"Vagal afferents mediate early satiation and prevent flavour avoidance learning in response to intraperitoneally infused Exendin-4","volume":"24","author":"Labouesse","year":"2012","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.peptides.2020.170389_bib0635","doi-asserted-by":"crossref","DOI":"10.2337\/db15-0973","article-title":"Knockdown of GLP-1 receptors in vagal afferents affects normal food intake and glycemia","volume":"65","author":"Krieger","year":"2016","journal-title":"Diabetes."},{"key":"10.1016\/j.peptides.2020.170389_bib0640","doi-asserted-by":"crossref","first-page":"R885","DOI":"10.1152\/ajpregu.00520.2015","article-title":"GLP-1 and weight loss: unraveling the diverse neural circuitry","volume":"310","author":"Kanoski","year":"2016","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0645","doi-asserted-by":"crossref","first-page":"4059","DOI":"10.1210\/en.2007-1743","article-title":"Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain Glucagon-Like-Peptide-1 receptor stimulation","volume":"149","author":"Hayes","year":"2008","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0650","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119034","article-title":"Activation of the GLP-1 receptors in the nucleus of the solitary tract reduces food reward behavior and targets the mesolimbic system","volume":"10","author":"Richard","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.peptides.2020.170389_bib0655","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1038\/npp.2016.246","article-title":"Endogenous Glucagon-like Peptide-1 Receptor Signaling in the Nucleus Tractus Solitarius is Required for Food Intake Control","volume":"42","author":"Alhadeff","year":"2017","journal-title":"Neuropsychopharmacology."},{"key":"10.1016\/j.peptides.2020.170389_bib0660","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1210\/en.2008-1479","article-title":"Endogenous hindbrain glucagon-like Peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling","volume":"150","author":"Hayes","year":"2009","journal-title":"Endocrinology."},{"key":"10.1016\/j.peptides.2020.170389_bib0665","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.cmet.2011.02.001","article-title":"Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like Peptide-1 receptor activation","volume":"13","author":"Hayes","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.peptides.2020.170389_bib0670","doi-asserted-by":"crossref","first-page":"R465","DOI":"10.1152\/ajpregu.00179.2014","article-title":"Hindbrain nucleus tractus solitarius glucagon-like peptide-1 receptor signaling reduces appetitive and motivational aspects of feeding","volume":"307","author":"Alhadeff","year":"2014","journal-title":"Am. J. Physiol. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0675","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2012.05.008","article-title":"Estradiol increases body weight loss and gut-peptide satiation after Roux-en-Y gastric bypass in ovariectomized rats","volume":"143","author":"Asarian","year":"2012","journal-title":"Gastroenterology."},{"key":"10.1016\/j.peptides.2020.170389_bib0680","doi-asserted-by":"crossref","DOI":"10.1152\/ajpregu.00446.2012","article-title":"Sex differences in the physiology of eating","volume":"305","author":"Asarian","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.peptides.2020.170389_bib0685","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1038\/nm.3009","article-title":"Targeted estrogen delivery reverses the metabolic syndrome","volume":"18","author":"Finan","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.peptides.2020.170389_bib0690","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s00125-014-3478-3","article-title":"GLP-1\u2013oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice","volume":"58","author":"Schwenk","year":"2015","journal-title":"Diabetologia."},{"key":"10.1016\/j.peptides.2020.170389_bib0695","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1172\/JCI80941","article-title":"Estrogen receptor\u2013\u03b1 in medial amygdala neurons regulates body weight","volume":"125","author":"Xu","year":"2015","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.peptides.2020.170389_bib0700","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.neuropharm.2016.07.039","article-title":"GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight","volume":"110","author":"Vogel","year":"2016","journal-title":"Neuropharmacology."},{"key":"10.1016\/j.peptides.2020.170389_bib0705","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.yhbeh.2017.05.012","article-title":"Estradiol modulates the anorexic response to central glucagon-like peptide 1","volume":"93","author":"Maske","year":"2017","journal-title":"Horm. Behav."}],"container-title":["Peptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196978120301388?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0196978120301388?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T09:27:36Z","timestamp":1759310856000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0196978120301388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":141,"alternative-id":["S0196978120301388"],"URL":"https:\/\/doi.org\/10.1016\/j.peptides.2020.170389","relation":{},"ISSN":["0196-9781"],"issn-type":[{"value":"0196-9781","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Estrogen and gut satiety hormones in vagus-hindbrain axis","name":"articletitle","label":"Article Title"},{"value":"Peptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.peptides.2020.170389","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"170389"}}