{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T09:05:37Z","timestamp":1791968737138,"version":"4.3.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22277038"],"award-info":[{"award-number":["22277038"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Hubei Province Natural Science Foundation","doi-asserted-by":"publisher","award":["2022CFB854"],"award-info":[{"award-number":["2022CFB854"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003464","name":"Hainan Normal University","doi-asserted-by":"publisher","award":["2024B29"],"award-info":[{"award-number":["2024B29"]}],"id":[{"id":"10.13039\/501100003464","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003464","name":"Hainan Normal University","doi-asserted-by":"publisher","award":["XJ2022A03"],"award-info":[{"award-number":["XJ2022A03"]}],"id":[{"id":"10.13039\/501100003464","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012554","name":"Hubei Provincial Department of Education","doi-asserted-by":"publisher","award":["B2023195"],"award-info":[{"award-number":["B2023195"]}],"id":[{"id":"10.13039\/100012554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012554","name":"Hubei Provincial Department of Education","doi-asserted-by":"publisher","award":["Q20223103"],"award-info":[{"award-number":["Q20223103"]}],"id":[{"id":"10.13039\/100012554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pesticide Biochemistry and Physiology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.pestbp.2025.106311","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T16:09:30Z","timestamp":1737994170000},"page":"106311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Design and synthesis of sulfur-containing pseudilin analogs and their biological activity evaluation"],"prefix":"10.1016","volume":"208","author":[{"given":"Jili","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aidong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pestbp.2025.106311_bb0005","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.3390\/molecules28031403","article-title":"The multifaceted MEP pathway: towards new therapeutic perspectives","volume":"28","author":"Allamand","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.pestbp.2025.106311_bb0010","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF00394363","article-title":"Autotoxic antibiotic production by a marine Chromobacterium","volume":"27","author":"Andersen","year":"1974","journal-title":"Mar. Biol."},{"key":"10.1016\/j.pestbp.2025.106311_bb0015","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ab.2004.10.011","article-title":"A colorimetric assay for the determination of 4-diphosphocytidyl-2-C-methyl-D-erythritol 4-phosphate synthase activity","volume":"337","author":"Bernal","year":"2005","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0020","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1021\/acs.chemrev.5b00484","article-title":"The halogen Bond","volume":"116","author":"Cavallo","year":"2016","journal-title":"Chem. Rev."},{"key":"10.1016\/j.pestbp.2025.106311_bb0025","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/00010694-196604000-00002","article-title":"The importance of sulfur as a plant nutrient in world crop production","volume":"101","author":"Coleman","year":"1966","journal-title":"Soil Sci."},{"key":"10.1016\/j.pestbp.2025.106311_bb0030","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s41061-017-0169-9","article-title":"Sulfur-containing agrochemicals","volume":"375","author":"Devendar","year":"2017","journal-title":"Top Curr. Chem. (Z)"},{"key":"10.1016\/j.pestbp.2025.106311_bb0035","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1039\/c1np00063b","article-title":"Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis","volume":"28","author":"Dickschat","year":"2011","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.pestbp.2025.106311_bb0040","doi-asserted-by":"crossref","first-page":"5675","DOI":"10.1021\/acs.chemrev.6b00537","article-title":"The methylerythritol phosphate pathway to isoprenoids","volume":"117","author":"Frank","year":"2017","journal-title":"Chem. Rev."},{"key":"10.1016\/j.pestbp.2025.106311_bb0045","first-page":"35","article-title":"Sulfur in pesticide action and metabolism","volume":"158","author":"Fukuto","year":"1981","journal-title":"Am. Chem. Soc."},{"key":"10.1016\/j.pestbp.2025.106311_bb0050","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1111\/j.1742-4658.2006.05133.x","article-title":"The crystal structure of a plant 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase exhibits a distinct quaternary structure compared to bacterial homologues and a possible role in feedback regulation for cytidine monophosphate","volume":"273","author":"Gabrielsen","year":"2006","journal-title":"FEBS J."},{"key":"10.1016\/j.pestbp.2025.106311_bb0055","doi-asserted-by":"crossref","first-page":"4960","DOI":"10.1021\/cr400265z","article-title":"Chromone: a valid scaffold in medicinal chemistry","volume":"114","author":"Gaspar","year":"2014","journal-title":"Chem. Rev."},{"key":"10.1016\/j.pestbp.2025.106311_bb0060","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1351\/pac199567081487","article-title":"Pesticides report 32: detection and significance of active metabolites of agrochemicals and related xenobiotics in animals (technical report)","volume":"67","author":"Hollingworth","year":"1995","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0065","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1002\/ps.7553","article-title":"Sulfur-based functional groups in agrochemistry","volume":"79","author":"Jeanguenat","year":"2023","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2025.106311_bb0070","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.bmc.2015.12.014","article-title":"Synthetic approaches to the 2010-2014 new agrochemicals","volume":"24","author":"Jeanmart","year":"2016","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0075","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1002\/anie.201309557","article-title":"Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD","volume":"53","author":"Kunfermann","year":"2014","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.pestbp.2025.106311_bb0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/17415990310001612290","article-title":"Sulfur chemistry in crop protection","volume":"25","author":"Lamberth","year":"2004","journal-title":"J. Sulfur Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0085","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2174\/0929867053363540","article-title":"Bioisosterism: a useful strategy for molecular modification and drug design","volume":"12","author":"Lima","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0090","doi-asserted-by":"crossref","first-page":"8042","DOI":"10.1002\/anie.200903743","article-title":"Total synthesis of pentabromo- and pentachloropseudilin, and synthetic analogues--allosteric inhibitors of myosin ATPase","volume":"48","author":"Martin","year":"2009","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.pestbp.2025.106311_bb0095","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1111\/jipb.13076","article-title":"An update on the function and regulation of methylerythritol phosphate and mevalonate pathways and their evolutionary dynamics","volume":"63","author":"Pu","year":"2021","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.pestbp.2025.106311_bb0100","doi-asserted-by":"crossref","first-page":"7941","DOI":"10.1021\/acs.jmedchem.6b01720","article-title":"Chromone as a privileged scaffold in drug discovery: recent advances","volume":"60","author":"Reis","year":"2017","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0105","doi-asserted-by":"crossref","first-page":"6451","DOI":"10.1073\/pnas.97.12.6451","article-title":"Biosynthesis of terpenoids: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase of Arabidopsis thaliana","volume":"97","author":"Rohdich","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.pestbp.2025.106311_bb0110","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1021\/acschembio.7b00004","article-title":"Mechanism of allosteric inhibition of the enzyme IspD by three different classes of ligands","volume":"12","author":"Schwab","year":"2017","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.pestbp.2025.106311_bb0115","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1126\/science.1137786","article-title":"Chimeras of two isoprenoid synthases catalyze all four coupling reactions in isoprenoid biosynthesis","volume":"316","author":"Thulasiram","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.pestbp.2025.106311_bb0120","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1146\/annurev-arplant-050312-120116","article-title":"Network analysis of the MVA and MEP pathways for isoprenoid synthesis","volume":"64","author":"Vranov\u00e1","year":"2013","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.pestbp.2025.106311_bb0125","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1039\/C8OB02994F","article-title":"I2\/DMSO-mediated multicomponent reaction of O-hydroxyaryl methyl ketones, Rongalite, and DMSO: access to C3-sulfenylated Chromones","volume":"17","author":"Wang","year":"2019","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0130","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1021\/acs.jafc.9b08057","article-title":"Synthesis and evaluation of halogenated 5-(2-Hydroxyphenyl)pyrazoles as Pseudilin analogues targeting the enzyme IspD in the Methylerythritol phosphate pathway","volume":"68","author":"Wang","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0135","article-title":"Design, synthesis, and herbicidal activity of indole-3-carboxylic acid derivatives as potential transport inhibitor response 1 antagonists","volume":"10","author":"Wang","year":"2022","journal-title":"Front. Chem."},{"key":"10.1016\/j.pestbp.2025.106311_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2024.105769","article-title":"Design, synthesis and activity evaluation of pseudilin analogs against cyanobacteria as IspD inhibitors","volume":"199","author":"Wang","year":"2024","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pestbp.2025.106311_bb0145","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/ps.7810","article-title":"Design and synthesis of fosmidomycin analogs containing aza-linkers and their biological activity evaluation","volume":"80","author":"Wu","year":"2024","journal-title":"Pest Manag. Sci."}],"container-title":["Pesticide Biochemistry and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357525000240?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357525000240?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T20:17:52Z","timestamp":1740514672000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048357525000240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":29,"alternative-id":["S0048357525000240"],"URL":"https:\/\/doi.org\/10.1016\/j.pestbp.2025.106311","relation":{},"ISSN":["0048-3575"],"issn-type":[{"value":"0048-3575","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Design and synthesis of sulfur-containing pseudilin analogs and their biological activity evaluation","name":"articletitle","label":"Article Title"},{"value":"Pesticide Biochemistry and Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pestbp.2025.106311","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106311"}}