{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:09:06Z","timestamp":1793311746822,"version":"4.5.0"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U25A20631"],"award-info":[{"award-number":["U25A20631"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pesticide Biochemistry and Physiology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.pestbp.2026.107182","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T02:23:54Z","timestamp":1779675834000},"page":"107182","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Rapid bactericidal and nematicidal activity of a ternary quaternary ammonium formulation via membrane disruption in bacteria and cuticle damage in Bursaphelenchus xylophilus"],"prefix":"10.1016","volume":"221","author":[{"given":"Mengyao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuewen","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongchao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingce","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Likun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chonglin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojie","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pestbp.2026.107182_bb0005","doi-asserted-by":"crossref","first-page":"9478","DOI":"10.1039\/D4TB00841C","article-title":"Advances in ionic liquid-based antimicrobial wound healing platforms","volume":"12","author":"Abdollahi","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.pestbp.2026.107182_bb0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1439-0329.2011.00733.x","article-title":"Insect vectors of the pinewood nematode: A review of the biology and ecology of Monochamus species","author":"Akbulut","year":"2012","journal-title":"For. Pathol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0015","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1111\/ppa.13875","article-title":"Pine wilt disease: a global threat to forestry","volume":"73","author":"Back","year":"2024","journal-title":"Plant Pathol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0020","series-title":"Pine Wilt Disease","author":"Bo","year":"2008"},{"key":"10.1016\/j.pestbp.2026.107182_bb0025","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00778-24","article-title":"Distinct biogeographic patterns for bacteria and fungi in association with Bursaphelenchus xylophilus nematodes and infested pinewood","volume":"12","author":"Cao","year":"2024","journal-title":"Microbiol. Spectrum"},{"key":"10.1016\/j.pestbp.2026.107182_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.140584","article-title":"Ecotoxicity and rapid degradation of quaternary ammonium compounds (QACs) subjected to combined vacuum UV and UV-C treatment","volume":"346","author":"Flanjak","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.pestbp.2026.107182_bb0035","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF02348216","article-title":"Physiological process of the symptom development and resistance mechanism in pine wilt disease","volume":"2","author":"Fukuda","year":"1997","journal-title":"J. For. Res."},{"key":"10.1016\/j.pestbp.2026.107182_bb0040","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1146\/annurev-phyto-081211-172910","article-title":"Pine wood nematode, Bursaphelenchus xylophilus","volume":"51","author":"Futai","year":"2013","journal-title":"Annu. Rev. Phytopathol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2024.116215","article-title":"Effective ciprofloxacin cationic antibacterial agent against persister bacteria with low hemolytic toxicity","volume":"267","author":"Gao","year":"2024","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.pestbp.2026.107182_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2025.178902","article-title":"Predicting high-risk zones for pine wood nematodes invasion: integrating climate suitability, host availability, and vector dominance","volume":"969","author":"Guo","year":"2025","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.pestbp.2026.107182_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/cells12040543","article-title":"Molecular defense response of Bursaphelenchus xylophilus to the nematophagous fungus Arthrobotrys robusta","volume":"12","author":"Hao","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.pestbp.2026.107182_bb0060","doi-asserted-by":"crossref","first-page":"6977","DOI":"10.1021\/acsnano.4c14689","article-title":"Enhancing antibiotic-resistant bacterial infection therapy: self-assembling gemini quaternary ammonium-functionalized peptide nanoassemblies with multiple antibacterial mechanisms","volume":"19","author":"He","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.pestbp.2026.107182_bb0065","doi-asserted-by":"crossref","first-page":"22047","DOI":"10.1021\/acs.jmedchem.5c02054","article-title":"Cheap, fast, safe, sustainable, and positively irresistible: the future of cationic amphiphilic disinfectant development","volume":"68","author":"Hedges","year":"2025","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.pestbp.2026.107182_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.117965","article-title":"The role of xylene as a nematicide formulation and its synergistic effects with abamectin in the management of pine wood nematodes","volume":"292","author":"Kang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.pestbp.2026.107182_bb0075","doi-asserted-by":"crossref","first-page":"7814","DOI":"10.1021\/acs.biomac.4c01099","article-title":"Antimicrobial macrocycles - synthesis, characterization, and activity comparison with their linear polycationic analogues","volume":"25","author":"Kopiasz","year":"2024","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.pestbp.2026.107182_bb0080","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.emcon.2022.06.005","article-title":"A surface sampling and liquid chromatography mass spectrometry method for the analysis of quaternary ammonium compounds collected from public transportation buses in New Jersey","volume":"8","author":"Lazofsky","year":"2022","journal-title":"Emerg. Contam."},{"key":"10.1016\/j.pestbp.2026.107182_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.126343","article-title":"Legacy pollution of floodplain soils with quaternary ammonium compounds - insights into vertical distribution, historical trends and suspected microplastic carriers","volume":"375","author":"Lennartz","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.pestbp.2026.107182_bb0090","doi-asserted-by":"crossref","first-page":"10299","DOI":"10.1021\/acs.jmedchem.5c00454","article-title":"Important role of triphenylamine in modulating the antibacterial performance relationships of antimicrobial peptide mimics by alkyl chain engineering","volume":"68","author":"Li","year":"2025","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.pestbp.2026.107182_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcis.2025.137891","article-title":"Unveiling the multifaceted mechanisms of action in nonionic and cationic biocide combinations against gram-negative bacteria","volume":"696","author":"Liao","year":"2025","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.pestbp.2026.107182_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.163781","article-title":"Low concentration quaternary ammonium compounds promoted antibiotic resistance gene transfer via plasmid conjugation","volume":"887","author":"Liu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.pestbp.2026.107182_bb0105","doi-asserted-by":"crossref","first-page":"8395","DOI":"10.1039\/D5TB00083A","article-title":"Compiling modules of photosensitizers and quaternary phosphonium blocks into material networks via a co-polymerization strategy: an effective way to fabricate antimicrobial agents against drug resistance","volume":"13","author":"Lv","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.pestbp.2026.107182_bb0110","doi-asserted-by":"crossref","first-page":"13781","DOI":"10.1021\/acsnano.4c02031","article-title":"Biomass-based, dual enzyme-responsive nanopesticides: eco-friendly and efficient control of pine wood nematode disease","volume":"18","author":"Ma","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.pestbp.2026.107182_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.177233","article-title":"Eco-friendly biocontrol of pine wilt disease: enhancing tree defense with Bacillus subtilis JCK-1398 for sustainable forest management","volume":"955","author":"Mannaa","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.pestbp.2026.107182_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13595-024-01233-y","article-title":"Improving monitoring and management methods is of the utmost importance in countries at risk of invasion by the pinewood nematode","volume":"81","author":"Robinet","year":"2024","journal-title":"Ann. For. Sci."},{"key":"10.1016\/j.pestbp.2026.107182_bb0125","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1002\/ps.8633","article-title":"Evidence for Bxy-npr-21 on controlling juveniles\u2019 growth and modulating male sexual arousal: from molecules to behaviors","volume":"81","author":"Shao","year":"2025","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.pestbp.2026.107182_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2025.128282","article-title":"Sugar-inducible promoters mitigate the fitness cost of engineered Serratia marcescens in the control of Monochamus alternatus","volume":"300","author":"Sheng","year":"2025","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.pestbp.2026.107182_bb0135","doi-asserted-by":"crossref","first-page":"6748","DOI":"10.1111\/pce.15655","article-title":"Comprehensive insights into pinewood nematode effectors: evolutionary diversity, functional roles, and implications for pine wilt disease management","volume":"48","author":"Song","year":"2025","journal-title":"Plant Cell Environ."},{"key":"10.1016\/j.pestbp.2026.107182_bb0140","doi-asserted-by":"crossref","first-page":"11707","DOI":"10.1021\/acs.est.4c02380","article-title":"Occurrence and distribution of antibacterial quaternary ammonium compounds in Chinese estuaries revealed by machine learning-assisted mass spectrometric analysis","volume":"58","author":"Su","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0145","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s10144-009-0145-5","article-title":"Individual-based modeling of the spread of pine wilt disease: vector beetle dispersal and the Allee effect","volume":"51","author":"Takasu","year":"2009","journal-title":"Popul. Ecol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0150","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.84621","article-title":"Hypoxia-induced tracheal elasticity in vector beetle facilitates the loading of pinewood nematode","volume":"12","author":"Tang","year":"2023","journal-title":"eLife"},{"key":"10.1016\/j.pestbp.2026.107182_bb0155","article-title":"Framework for modelling economic impacts of invasive species, applied to pine wood nematode in Europe","volume":"7","author":"Tarek","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.pestbp.2026.107182_bb0160","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10658-011-9924-x","article-title":"Pine wilt disease: a threat to European forestry","volume":"133","author":"Vicente","year":"2012","journal-title":"Eur. J. Plant Pathol."},{"key":"10.1016\/j.pestbp.2026.107182_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142948","article-title":"Unraveling the interactions of Esteya vermicola, pinewood nematode, and pine hosts: insights into population dynamics and molecular responses","volume":"363","author":"Wang","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.pestbp.2026.107182_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2025.123206","article-title":"Synergistic effects of quaternary ammonium compounds and antibiotics on the evolution of antibiotic resistance","volume":"275","author":"Wang","year":"2025","journal-title":"Water Res."},{"key":"10.1016\/j.pestbp.2026.107182_bb0175","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20133342","article-title":"Bacterial communities and virulence associated with pine wood nematode Bursaphelenchus xylophilus from different Pinus spp.","volume":"20","author":"Xue","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.pestbp.2026.107182_bb0180","series-title":"Pine Wilt Disease in China, (Pine Wilt Disease)","author":"Zhao","year":"2008"},{"key":"10.1016\/j.pestbp.2026.107182_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.141386","article-title":"Quaternary ammonium salts for water treatment with balanced rate of sterilization and degradation","volume":"352","author":"Zhou","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.pestbp.2026.107182_bb0190","doi-asserted-by":"crossref","DOI":"10.1038\/s41597-025-04460-8","article-title":"Chromosome-level genome assembly of the pine wood nematode carrier Arhopalus unicolor","volume":"12","author":"Zou","year":"2025","journal-title":"Sci. Data"}],"container-title":["Pesticide Biochemistry and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526002439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0048357526002439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T13:44:47Z","timestamp":1785159887000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0048357526002439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":38,"alternative-id":["S0048357526002439"],"URL":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107182","relation":{},"ISSN":["0048-3575"],"issn-type":[{"value":"0048-3575","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid bactericidal and nematicidal activity of a ternary quaternary ammonium formulation via membrane disruption in bacteria and cuticle damage in Bursaphelenchus xylophilus","name":"articletitle","label":"Article Title"},{"value":"Pesticide Biochemistry and Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107182","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107182"}}